Publications - Hung - 2025
Bond AN, Orzechowski M, Zhang S, Ben-Zion I, Lemmer A, Garry N, Lee K, Chen M, Delano K, Gath E, Golas AL, Nietupski R, Fitzgerald M, Ehrt S, Rubin EJ, Sassetti CM, Schnappinger D, Shoresh N, Hunt DK, Gomez JE, Hung DT
Reference-based chemical-genetic interaction profiling to elucidate small molecule mechanism of action in Mycobacterium tuberculosis. Nat Commun. 2025;16(1):9673 - PMID: 41184262 - PMCID: PMC12583738 - DOI: 10.1038/s41467-025-64662-xGoering ER, Clatworthy AE, Parada-Kusz M, Bagnall J, Hung DT
Kmo restricts Salmonella in a whole organism infection model by promoting macrophage lysosomal acidification through kainate receptor antagonism. PLoS Pathog. 2025;21(10):e1013273 - PMID: 41129589 - PMCID: PMC12571273 - DOI: 10.1371/journal.ppat.1013273Neo DM, Ben-Zion I, Bagnall J, Solomon MY, Bond AN, Gath E, Zhang S, Shoresh N, Gomez J, Hung DT
A Multiplexed, Target-Based Phenotypic Screening Platform Using CRISPR Interference in Mycobacterium abscessus. ACS Infect Dis. 2025;11(11):3263-3275 - PMID: 41139833 - PMCID: PMC12624723 - DOI: 10.1021/acsinfecdis.5c00623Penaranda C, Brenner EP, Clatworthy AE, Cosimi LA, Ravi J, Hung DT
Mapping genetic and phenotypic diversity of Pseudomonas aeruginosa across clinical and environmental isolation sites. bioRxiv. 2025;:ePub - PMID: 41040319 - PMCID: PMC12485682 - DOI: 10.1101/2025.09.22.677895Sullivan JR, Ferrara K, Barrick R, Romano KP, Warrier T, Hung DT
An Inducible CRISPRi system for phenotypic analysis of essential genes in Pseudomonas aeruginosa. bioRxiv. 2025;:ePub - PMID: 40964384 - PMCID: PMC12439951 - DOI: 10.1101/2025.09.11.675340
