About Us

In addition to inquiries into the origins of life, atherosclerosis, host-pathogen interactions, and physiological harbingers of advers outcomes, CCIB supports investigators at the hospital and across Boston through our autonomous cores that provide services in DNA sequencing, oligonucleotide synthesis and research laboratory automation.

Careers

Program: DNA Core
Date Posted: 2017-05-30
Description
The CCIB DNA Core has opened up a full-time position for a Research Technologist. As a member of the DNA Core, the ResearchTechnologist will provide standard and custom medium- to high-throughput sample processing services for various molecular biology and genomics applications, including maintenance of automated laboratory workstations, and will participate in the development, implementation and execution of automated molecular biology procedures and processes. The Research Technologist reports directly to Core Director, and/or managers of the core laboratory and is expected to work independently on assigned research with minimal guidance from a higher level staff member. The ideal candidate must be able to learn and work in a collaborative and fast-paced team environment, and to interact with all levels of staff and with researchers using our services. He/she will have good organizational and time management skills as well as an ability both to follow directions carefully and to solve common problems independently. We are looking for a team member who can learn quickly and is enthusiastic about laboratory automation instruments and devices and methodologies used to enable, expedite and increase the efficiency and effectiveness of scientific research. Review of applications will begin immediately and continue until the position is filled. Salary will be commensurate with the candidate’s experience and qualifications. The position typically requires a bachelor’s degree or higher plus three years of related experience, or an equivalent combination of education and experience.
Responsibilities
Develops, validates, and applies high-throughput methods for various scientific applications using and programming laboratory automation. Provides standard and custom medium- to high-throughput sample processing services for molecular biology and genomics applications (including but not limited to Custom Automation projects, Mouse Genotyping, 96-well Plasmid Preparation, High-Throughput Library Screening, and Next-Generation Sequencing (NGS) Library Preparation). Working with senior personnel, performs early research and development activity to create new core services that are robust, cost-effective and time efficient. Collaborates with core customers (senior scientists and postdoctoral research fellows) to transfer new assays and methods to automation platforms. Works closely with IT group and instrument vendors to develop and implement integration layers between automation platform and the LIMS systems. Develops project timelines and utilizes time management practices and tools to manage demands and deadlines and to deliver on key project milestones; proactively communicates impending changes in work, project schedules and experimental design. Accurately and consistently records experimental methods, materials and results in laboratory notebooks. Analyzes data, evaluates results, forms conclusions, and determines future experiments. Uses broad knowledge of molecular biology techniques to proactively troubleshoot assays, to resolve technical issues and challenges, and to perform data interpretation. Presents findings or comprehensive project status reviews at internal meetings. Applies advanced technical writing and graphical skills to produce documents and reports. Writes and implements standard operation procedures (SOPs). Determines all chemicals, reagents and supplies needed for a project; develops a strong knowledge of all related third-party vendors and their technologies and products. Maintains and troubleshoots liquid handling platforms, including cleanliness of work areas and instrument scheduling for various core and collaborator activities. Assists Core Director in cost modeling and in the analysis of yearly volumes of automation services for the core budget process. Flexibility in a fast-paced, changing environment; be willing to accept responsibilities outside of the initial job description. Establishes and maintains productive relationship with all core personnel; develops internal and external collaborations. For specific research services, works as a liaison between core laboratory and customers.
Requirements
Strong molecular biology background and good hands-on knowledge of the latest molecular biology methods Experience operating and programming liquid-handling robotics Proficiency in Microsoft Word, Excel, and PowerPoint Excellent general laboratory and organizational skills including the ability to multitask and to work independently and well as part of a team Superior time management skills Excellent communication skills (written and verbal) and orientation toward teamwork and collaboration Critical thinking, excellent data analysis and interpretation skills, good problem solving skills Preferred: Background in automated sample processing Ability to operate LIMS Experience in: Laboratory Automation/Liquid Handling; High-throughput sample processing; cDNA screening; Mouse Genotyping; Next-Generation sequencing methods and library preparation; Real-time PCR; Advanced molecular biology techniques used in Genomics Next-Generation Sequencing using Illumina instruments such as MiSeq Education: The candidate must have a bachelor’s degree or higher in the Life Sciences, with strong training in the theory and practice of molecular biology, plus a minimum of three years experience in a research environment (5 years preferred), or an equivalent combination of education and experience. Specific experience in programming and use of laboratory robotics for high-throughput sample processing is required. LIMS experience and/or familiarity with some of the technologies listed under Responsibilities is a plus. Some related work experience in a fast-paced and multi-tasked environment is preferred.

FAQs

Staff

Lynelle Cortellini

Administrative Manager, Research

Marc Davignon

Systems Manager

Chris Kelleher

Facilities Manager

Chia-Chia Lu

Project Coordinator

Tara Thurber

Administrative Director, Research

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The Center for Computational and Integrative Biology

The Center for Computational and Integrative Biology
Massachusetts General Hospital
Richard B. Simches Research Center
185 Cambridge Street
7th Floor
Boston, MA 02114
Fax: 617.643.3328

Roger Albright

Senior Clinical Research Project Mgr

James Angstman

Research Technician II

Julian Banerji

Visiting Scientist

Kristina Belanger

Senior Research Technologist

Stephen Belmonte

Senior Research Technologist

Jason Bishai

Associate Computational Biologist

Priya Bowden

QA MGR, REG AFFAIRS/OPERATIONS

Peter Breen

Research Technician

Jennifer Bush

Greenhouse Manager

Zhifang Cao

Non-Clinical PhD

Sarah Carden

Research Fellow

Christopher Carr

Research Scientist (MIT)

Brent Cezairliyan

Research Fellow

Glen Cho

Research Team Leader I

Nicole Chumbler

Research Fellow

Linda Chun

Non-Clinical PhD

Hoo Sun Chung

Research Associate

Anne Clatworthy

Research Scientist II

Senya Combs

Research Tech I

Annie Lee Conery

Research Team Leader I

Lynelle Cortellini

Administrative Manager, Research

John Darga

Lab Manager

Sandip Datta

Research Scientist

Marc Davignon

Systems Manager

A. Nicole Desch

NON EMPLOYEE RESEARCH

Stacie Dodgson

Non Employee Research

Hao Du

Research Fellow

Daniel Duzdevich

Research Fellow

Karen Elmessadi

Research Technologist, Sequencing

Christoph Ernst

Research Fellow

Sylvia Fischer

Research Fellow

Michael Fitzgerald

Assistant Professor in Medicine

Shannon Fracchia

Clinical Fellow

Mason Freeman

Director, Translational Medicine Group

Elena Getmanova

Research Team Leader II

Constantin Giurgiu

Graduate Student

Daniel Graham

Non-Clinical PhD

Stefan Halvorsen

Research Technician II

Yuan-Di Halvorsen

Research Project Leader

Nitya Jain

Research Fellow

Wenzhi Jiang

Research Associate

Lin Jin

Graduate Student

Chris Kelleher

Facilities Manager

Seohyun (Chris) Kim

Graduate Student

Marina Kniazeva

Assistant in Molecular Biology

Parimal Korgaonkar

Sr. Research Technologist

Alexander Kovtun

Research Team Leader II

Victor Lelyveld

Research Fellow

Tsz (Jacky) Leung

Research Technician II

Lei Li

Research Associate

Li Li

Sr. Research Technologist

Xiaoyan Li

Clinical Trial Manager

Li Li

Research Fellow

Pauline Lim

Administrative Assistant

Hong Liu

Research Specialist

Huan Yi Liu

Research Lab Assistant

Kai Liu

Research Fellow

Ying Liu

Research Team Leader I

Steven Lombardo

Research Technologist

Chia-Chia Lu

Project Coordinator

Naifang Lu

Research Lab Manager

Chengwei Luo

Research Fellow

Matthew McCormack

Research Fellow

Deborah McEwan

Research Fellow

Michael Mirisola

Research Technician II

Andrew Moeller

Research Technologist

Vishnu Mohanan

Research Fellow

Toru Nakata

Research Fellow

Martin Newman

Research Fellow

Aylwin Ng

Instructor in Medicine, HMS; Assistant in Immunology, MGH

Derek O'Flaherty

Research Fellow

Tivoli Olsen

Research Fellow

Ayan Pal

Research Fellow

Nicholas Paquette

Research Technologist

Margarita Parada

Research Fellow

Geraldine Paulus

Research Fellow

Lydia Pazienza

Graduate Student

Christine Petersen

Non Employee - Research Fellow

Julia Plotnikov

Research Staff

Caryn Porter

Research Lab Manager

Brad Poulsen

Research Fellow

Diane Sacchetti

Administrative Assistant

Slim Sassi

Non-Clinical PhD

Prabhat Singhal

Research Associate

Anna Sokolovska

Research Fellow

Nicole Stange-Thomann

Research Team Leader II --> DNA Core Director

Kyle Strom

Research Fellow

Lin Sun

Senior Research Project Leader

Thomas Sundberg

Non-Employee Research

Jack Szostak

Principal Investigator

Caroline Tan

Research Specialist

Antoine Tanne

Research Fellow

Chia-Lun (Jack) Tsai

Research Team Leader II

Travis Walton

Graduate Student

Huajun Wang

Bioinformatics Specialist II

Qingyi Wang

Research Technologist

Anna Wang

Research Fellow

Kurt Warnhoff

Research Fellow

Wei Wei

Research Fellow

Yue Wu

Researcn Fellow

Baihua Xu

Research Team Leader I

Jinjin Xu

Research Fellow

Wenting Xu

Research Scholar

Junmei Yao

Research Lab Manager

Moran Yassour

Non-Employee Research

Ruiqiang Ye

Research Fellow

Shen (Peter) Yu

Research Fellow

Anna Zagieboylo

Research Technician I

Wen Zhang

Research Fellow

Guoling Zhou

Research Team Leader II

Lijun Zhou

Research Fellow