Value of the history and stool occult blood test in selection of patients for upper endoscopy in Zimbabwe.

Peroxynitrite-induced rat colitis--a new model of colonic inflammation.

Nonreceptor tyrosine kinases in aggregation-mediated cell activation.

Malignant epithelioid hemangioendothelioma of the tibia associated with a bone infarct in a patient who had Gaucher disease. A case report.

Enzyme replacement therapy for Gaucher disease: skeletal responses to macrophage-targeted glucocerebrosidase.

Atheroembolic renal failure after invasive procedures. Natural history based on 52 histologically proven cases.

Clustered syk tyrosine kinase domains trigger phagocytosis.

Transgenic expression of tpr-met oncogene leads to development of mammary hyperplasia and tumors.

Paracoccidioidomycosis of bones and joints. A clinical, radiologic, and pathologic study of 9 cases.

SEK1/MKK4 is required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development.

Membrane compartmentation is required for efficient T cell activation.

Tumor induction of VEGF promoter activity in stromal cells.

Health information in the developing world.

Membrane compartmentation and the response to antigen.

A paradoxical reduction in susceptibility to colonic injury upon targeted transgenic ablation of goblet cells.

Fractalkine is an epithelial and endothelial cell-derived chemoattractant for intraepithelial lymphocytes in the small intestinal mucosa.

Microbiology. How to get along--friendly microbes in a hostile world.

Mechanisms of NSAID-induced gastrointestinal injury defined using mutant mice.

TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome.

Gaucher disease. New approaches to an ancient disease.

Hepatitis C virus replication is directly inhibited by IFN-alpha in a full-length binary expression system.

L-histidine decarboxylase decreases its own transcription through downregulation of ERK activity.

Role of tumor necrosis factor receptor 2 (TNFR2) in colonic epithelial hyperplasia and chronic intestinal inflammation in mice.

Identification of a novel Ras-regulated proapoptotic pathway.

Decreased bone density in splenectomized Gaucher patients receiving enzyme replacement therapy.

Transforming growth factor-beta mediates intestinal healing and susceptibility to injury in vitro and in vivo through epithelial cells.

Essential role for Vav1 in activation, but not development, of gammadelta T cells.

Colonic epithelial functional phenotype varies with type and phase of experimental colitis.

Homer-3 regulates activation of serum response element in T cells via its EVH1 domain.

Paradoxical roles of different nitric oxide synthase isoforms in colonic injury.

Chemotherapy- and radiotherapy-induced intestinal damage is regulated by intestinal trefoil factor.

The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death.

Discs large (Dlg1) complexes in lymphocyte activation.

Wave2 activates serum response element via its VCA region and functions downstream of Rac.

Bioluminescence resonance energy transfer identify scaffold protein CNK1 interactions in intact cells.

GRIM-19 interacts with nucleotide oligomerization domain 2 and serves as downstream effector of anti-bacterial function in intestinal epithelial cells.

Commensal flora: wolf in sheep's clothing.

PDZ domains and the politics of polarity in lymphocytes.

Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognition.

Large-scale screens for cDNAs with in vivo activity.

Nore1B regulates TCR signaling via Ras and Carma1.

CARMA1 is critical for the development of allergic airway inflammation in a murine model of asthma.

Immune cell transcriptome datasets reveal novel leukocyte subset-specific genes and genes associated with allergic processes.

Isolation and analysis of lipid rafts in cell-cell interactions.

Ca2+/calmodulin-dependent protein kinase II is a modulator of CARMA1-mediated NF-kappaB activation.

A molecular-properties-based approach to understanding PDZ domain proteins and PDZ ligands.

Paeonol attenuates TNBS-induced colitis by inhibiting NF-kappaB and STAT1 transactivation.

Centaurin beta1 down-regulates nucleotide-binding oligomerization domains 1- and 2-dependent NF-kappaB activation.

Bcl10 is phosphorylated on Ser138 by Ca2+/calmodulin-dependent protein kinase II.

ABCA3 inactivation in mice causes respiratory failure, loss of pulmonary surfactant, and depletion of lung phosphatidylglycerol.

Vav proteins control MyD88-dependent oxidative burst.

Discs-large homolog 1 regulates smooth muscle orientation in the mouse ureter.

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.

Molecular pathogenesis of inflammatory bowel disease: genotypes, phenotypes and personalized medicine.

Unravelling the pathogenesis of inflammatory bowel disease.

DLGH1 is a negative regulator of T-lymphocyte proliferation.

DLG1 is an anchor for the E3 ligase MARCH2 at sites of cell-cell contact.

Wiskott Aldrich syndrome protein (WASP) and N-WASP are critical for T cell development.

AKAP13, a RhoA GTPase-specific guanine exchange factor, is a novel regulator of TLR2 signaling.

SNPping away at the pathogenesis of Crohn's disease.

Identification of host proteins required for HIV infection through a functional genomic screen.

Defective signal transduction in B lymphocytes lacking presenilin proteins.

Gene-centric association mapping of chromosome 3p implicates MST1 in IBD pathogenesis.

IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis.

Autophagy as an important process in gut homeostasis and Crohn's disease pathogenesis.

Improvement of bone disease by imiglucerase (Cerezyme) therapy in patients with skeletal manifestations of type 1 Gaucher disease: results of a 48-month longitudinal cohort study.

Defining molecular classifications and targets in gastroenteropancreatic neuroendocrine tumors through DNA microarray analysis.

Spinophilin and the immune synapse.

Neither hide nor hair: the difficulty of identifying useful disease biomarkers.

SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter.

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.

The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response.

Molecular association between beta-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/beta-catenin signaling.

Hoxc6 is overexpressed in gastrointestinal carcinoids and interacts with JunD to regulate tumor growth.

MAST3: a novel IBD risk factor that modulates TLR4 signaling.

Genome-wide association studies: a new window into immune-mediated diseases.

Genome-wide association studies: a new window into immune-mediated diseases.

CARMA3 mediates lysophosphatidic acid-stimulated cytokine secretion by bronchial epithelial cells.

RNA interference screen for human genes associated with West Nile virus infection.

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease.

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells.

Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant.

Role for beta-catenin and HOX transcription factors in Caenorhabditis elegans and mammalian host epithelial-pathogen interactions.

Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway.

The Nore1B/Mst1 complex restrains antigen receptor-induced proliferation of naïve T cells.

Rassf family of tumor suppressor polypeptides.

Differential requirement for CARMA1 in agonist-selected T-cell development.

On the level: IRGM gene function is all about expression.

HIF-1alpha and HIF-2alpha have divergent roles in colon cancer.

Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis.

A functional genomic screen identifies cellular cofactors of hepatitis C virus replication.

Selective activation of nuclear factor kappa B in the cochlea by sensory and inflammatory stress.

Selective activation of nuclear factor kappa B in the cochlea by sensory and inflammatory stress.

A novel hybrid yeast-human network analysis reveals an essential role for FNBP1L in antibacterial autophagy.

The cytoskeletal scaffold Shank3 is recruited to pathogen-induced actin rearrangements.

An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia.

Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions.

Identification of Atg5-dependent transcriptional changes and increases in mitochondrial mass in Atg5-deficient T lymphocytes.

Building complex biological networks based upon model organisms: mapping the human autophagy interactome via a hybrid yeast-human protein interaction network.

A genome-wide genetic screen for host factors required for hepatitis C virus propagation.

Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly.

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43.

Autophagy, immunity and human disease.

Common variants at five new loci associated with early-onset inflammatory bowel disease.

The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus.

Autophagy at the gut interface: mucosal responses to stress and the consequences for inflammatory bowel diseases.

Genome-wide association identifies multiple ulcerative colitis susceptibility loci.

Exploring the interplay of barrier function and leukocyte recruitment in intestinal inflammation by targeting fucosyltransferase VII and trefoil factor 3.

Gene enrichment profiles reveal T-cell development, differentiation, and lineage-specific transcription factors including ZBTB25 as a novel NF-AT repressor.

Differential expression of microRNA (miRNA) in chordoma reveals a role for miRNA-1 in Met expression.

Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine.

Characterization and analysis of human chordoma cell lines.

A genome-wide siRNA screen reveals multiple mTORC1 independent signaling pathways regulating autophagy under normal nutritional conditions.

Human leucine-rich repeat proteins: a genome-wide bioinformatic categorization and functional analysis in innate immunity.

A systems biology viewpoint on autophagy in health and disease.

Wnt signaling regulates mitochondrial physiology and insulin sensitivity.

Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease.

Human IRGM gene "to be or not to be".

NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis.

LRRK2 is involved in the IFN-gamma response and host response to pathogens.

Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection.

Failure and exploitation of autophagy in human pathologies-cellular integrity between inflammation, infection, and cell survival.

Control and manipulation of pathogens with an optical trap for live cell imaging of intercellular interactions.

Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology.

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

Crohn disease: a current perspective on genetics, autophagy and immunity.

Bacterial and host determinants of MAL activation upon EPEC infection: the roles of Tir, ABRA, and FLRT3.

Recurrent chromosomal copy number alterations in sporadic chordomas.

MyD88-dependent TLR1/2 signals educate dendritic cells with gut-specific imprinting properties.

A Francisella tularensis locus required for spermine responsiveness is necessary for virulence.

Genetics and pathogenesis of inflammatory bowel disease.

Use of an optical trap for study of host-pathogen interactions for dynamic live cell imaging.

Control of NOD2 and Rip2-dependent innate immune activation by GEF-H1.

Leucine-rich repeat (LRR) proteins: integrators of pattern recognition and signaling in immunity.

Phosphoprotein associated with glycosphingolipid-enriched microdomains differentially modulates SRC kinase activity in brain maturation.

HCV causes chronic endoplasmic reticulum stress leading to adaptation and interference with the unfolded protein response.

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease.

Genome-wide expression profiling implicates a MAST3-regulated gene set in colonic mucosal inflammation of ulcerative colitis patients.

Caspase 8 inhibits programmed necrosis by processing CYLD.

CARMA1 is necessary for optimal T cell responses in a murine model of allergic asthma.

Image-based genome-wide siRNA screen identifies selective autophagy factors.

Autophagy suppresses interleukin-1? (IL-1?) signaling by activation of p62 degradation via lysosomal and proteasomal pathways.

Genome-wide siRNA screen for mediators of NF-?B activation.

Tribbles 2 (Trib2) is a novel regulator of toll-like receptor 5 signaling.

ONCOGENIC KRAS REGULATES BMP4 EXPRESSION IN COLON CANCER CELL LINES.

Guidelines for the use and interpretation of assays for monitoring autophagy.

Nondegradative Role of Atg5-Atg12/ Atg16L1 Autophagy Protein Complex in Antiviral Activity of Interferon Gamma.

Autophagy and the immune system.

Regulation of monocyte functional heterogeneity by miR-146a and Relb.

Establishment and characterization of a novel chordoma cell line: CH22.

Helminth Infection Impairs Autophagy-Mediated Killing of Bacterial Enteropathogens by Macrophages.

Non-invasive mapping of the gastrointestinal microbiota identifies children with inflammatory bowel disease.

Case 23-2012.

Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes.

Enhanced Tim3 activity improves survival after influenza infection.

Enhanced Tim3 Activity Improves Survival after Influenza Infection.

p40phox Expression Regulates Neutrophil Recruitment and Function during the Resolution Phase of Intestinal Inflammation.

Essential cell autonomous role for interferon regulatory factor 1 in interferon-?-mediated inhibition of norovirus replication in macrophages.

Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes.

Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment.

Common alleles that influence autophagy and the risk for inflammatory bowel disease.

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

The LRR and RING Domain Protein LRSAM1 Is an E3 Ligase Crucial for Ubiquitin-Dependent Autophagy of Intracellular Salmonella Typhimurium.

Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans.

Angiotensin II Drives the Production of Tumor-Promoting Macrophages.

ATG5 regulates plasma cell differentiation.

Identification of a candidate therapeutic autophagy-inducing peptide.

Autophagy modulates Borrelia burgdorferi-induced production of interleukin-1? (IL-1?).

?-6 Polyunsaturated fatty acids extend life span through the activation of autophagy.

Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing.

Development of a Colon Cancer GEMM-Derived Orthotopic Transplant Model for Drug Discovery and Validation.

Cutting Edge: cell-autonomous control of IL-7 response revealed in a novel stage of precursor B cells.

Polarity gene discs large homolog 1 regulates the generation of memory T cells.

Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection.

Succinate is an inflammatory signal that induces IL-1? through HIF-1?.

Genome-wide Analysis of Immune System Genes by Expressed Sequence Tag Profiling.

From genetics of inflammatory bowel disease towards mechanistic insights.

Concomitant BRAF and PI3K/mTOR Blockade Is Required for Effective Treatment of BRAFV600E Colorectal Cancer.

How Does Genotype Influence Disease Phenotype in Inflammatory Bowel Disease?

Conformational stability, vibrational spectra, HOMO-LUMO and NBO analysis of 1,3,4-thiadiazolidine-2,5-dithione with experimental (FT-IR and FT-Raman) techniques and scaled quantum mechanical calculations.

Card9 Mediates Intestinal Epithelial Cell Restitution, T-helper 17 Responses, and Control of Bacterial Infection in Mice.

Skin Microbiome Imbalance in Patients with STAT1/STAT3 Defects Impairs Innate Host Defense Responses.

Genetic risk factors for Clostridium difficile infection in ulcerative colitis.

Functional profiling of the gut microbiome in disease-associated inflammation.

Beclin 2 Functions in Autophagy, Degradation of G Protein-Coupled Receptors, and Metabolism.

Atg16l1 is Required for Autophagy in Intestinal Epithelial Cells and Protection of Mice from Salmonella Infection.

Deep Resequencing of GWAS Loci Identifies Rare Variants in CARD9, IL23R and RNF186 That Are Associated with Ulcerative Colitis.

Genetic Variants Synthesize to Produce Paneth Cell Phenotypes that Define Subtypes of Crohn's Disease.

Advances in inflammatory bowel disease pathogenesis: linking host genetics and the microbiome.

Novel Mechanism of Tumor Suppression by Polarity Gene Discs Large 1 (DLG1) Revealed in a Murine Model of Pediatric B-ALL.

Selective Modulation of Autophagy, Innate Immunity, and Adaptive Immunity by Small Molecules.

Long-Lasting Effects of BCG Vaccination on Both Heterologous Th1/Th17 Responses and Innate Trained Immunity.

Autophagy at the crossroads of metabolism and cellular defense.

Autophagy is redundant for the host defense against systemic Candida albicans infections.

Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia.

Autophagy is essential for cardiac morphogenesis during vertebrate development.

Differential Effect of Genetic Burden on Disease Phenotypes in Crohn's Disease and Ulcerative Colitis: Analysis of a North American Cohort.

SMAD3 gene variant is a risk factor for recurrent surgery in patients with Crohn's disease.

The Microbiome in Inflammatory Bowel Diseases: Current Status and the Future Ahead.

IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans.

Human Genome-Wide RNAi Screen Identifies an Essential Role for Inositol Pyrophosphates in Type-I Interferon Response.

The treatment-naive microbiome in new-onset Crohn's disease.

Genetic Polymorphisms in Metabolizing Enzymes Modifying the Association Between Smoking and Inflammatory Bowel Diseases.

Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense.

Dectin-1 dependent LC3 recruitment to phagosomes enhances fungicidal activity in macrophages.

Inflammatory Bowel Disease as a Model for Translating the Microbiome.

SLCO3A1, a Novel Crohn's Disease-Associated Gene, Regulates NF-?B Activity and Associates with Intestinal Perforation.

Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature.

Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells.

An alteration in ATG16L1 stability in Crohn disease.

Multivariate inference of pathway activity in host immunity and response to therapeutics.

mTOR- and HIF-1?-mediated aerobic glycolysis as metabolic basis for trained immunity.

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity.

Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

Immunochip SNP array identifies novel genetic variants conferring susceptibility to candidaemia.

Small-molecule control of cytokine function: new opportunities for treating immune disorders.

Transmembrane adaptor protein PAG/CBP is involved in both positive and negative regulation of mast cell signaling.

CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling.

An Image-Based Genetic Assay Identifies Genes in T1D Susceptibility Loci Controlling Cellular Antiviral Immunity in Mouse.

Genetics of immune-mediated disorders: from genome-wide association to molecular mechanism.

BCG-induced trained immunity in NK cells: Role for non-specific protection to infection.

Autophagy Controls BCG-Induced Trained Immunity and the Response to Intravesical BCG Therapy for Bladder Cancer.

Autophagy and checkpoints for intracellular pathogen defense.

Complex host genetics influence the microbiome in inflammatory bowel disease.

Early life environment and natural history of inflammatory bowel diseases.

Pyruvate Kinase M2 Regulates Hif-1? Activity and IL-1? Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages.

Disease-Specific Alterations in the Enteric Virome in Inflammatory Bowel Disease.

The Dynamics of the Human Infant Gut Microbiome in Development and in Progression toward Type 1 Diabetes.

A novel role for KLF14 in T regulatory cell differentiation.

Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature.

Associations between host gene expression, the mucosal microbiome, and clinical outcome in the pelvic pouch of patients with inflammatory bowel disease.

Discovery of a Small-Molecule Probe for V-ATPase Function.

An Integrative View of Microbiome-Host Interactions in Inflammatory Bowel Diseases.

The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells.

CARMA3 Is Critical for the Initiation of Allergic Airway Inflammation.

Identification of an anti-inflammatory protein from Faecalibacterium prausnitzii, a commensal bacterium deficient in Crohn's disease.

Integrated Genomics of Crohn's Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy.

Role of Autophagy in the Maintenance of Intestinal Homeostasis.

Body Mass Index, Genetic Susceptibility, and Risk of Complications Among Individuals with Crohn's Disease.

Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics.

Functional genomics identifies negative regulatory nodes controlling phagocyte oxidative burst.

Growth dynamics of gut microbiota in health and disease inferred from single metagenomic samples.

Common Genetic Variants Influence Circulating Vitamin D Levels in Inflammatory Bowel Diseases.

Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses.

Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses.

ConStrains identifies microbial strains in metagenomic datasets.

A Noncanonical Autophagy Pathway Restricts Toxoplasma gondii Growth in a Strain-Specific Manner in IFN-?-Activated Human Cells.

A Noncanonical Autophagy Pathway Restricts Toxoplasma gondii Growth in a Strain-Specific Manner in IFN-?-Activated Human Cells.

The Gut Microbiome Contributes to a Substantial Proportion of the Variation in Blood Lipids.

Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation.

Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation.

Flow Cytometric Analysis of Mononuclear Phagocytes in Non-diseased Human Lung and Lung-draining Lymph Nodes.

Proton pump inhibitors affect the gut microbiome.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Sub-clinical detection of gut microbial biomarkers of obesity and type 2 diabetes.

New Regulatory Roles of Galectin-3 in the High-affinity IgE Receptor Signaling.

Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann-Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn's disease.

?v Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells.

Timothy C. Wang, MD: Our next AGA President.

Trained immunity: A program of innate immune memory in health and disease.

Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans.

Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans.

Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity.

Mechanisms of Pediatric Inflammatory Bowel Disease.

Clinical Activity and Quality of Life Indices Are Valid Across Ulcerative Colitis But Not Crohn's Disease Phenotypes.

Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease.

CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands.

Simultaneous Pathway Activity Inference and Gene Expression Analysis Using RNA Sequencing.

Development of Chemical Probes for Investigation of Salt-Inducible Kinase Function In Vivo.

Metagenomic Characterization of Microbial Communities In Situ Within the Deeper Layers of the Ileum in Crohn's Disease.

Natural history of the infant gut microbiome and impact of antibiotic treatment on bacterial strain diversity and stability.

Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans.

Genetic Coding Variant in GPR65 Alters Lysosomal pH and Links Lysosomal Dysfunction with Colitis Risk.

The T300A Crohn's disease risk polymorphism impairs function of the WD40 domain of ATG16L1.

Profiling DNA damage-induced phosphorylation in budding yeast reveals diverse signaling networks.

Microbiota as Therapeutic Targets.

Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62.

Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi.

Dysbiosis, inflammation, and response to treatment: a longitudinal study of pediatric subjects with newly diagnosed inflammatory bowel disease.

A pleiotropic missense variant in SLC39A8 is associated with Crohn's disease and human gut microbiome composition.

Understanding human immune function using the resources from the Human Functional Genomics Project.

A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis.

Characterization of candidate genes in inflammatory bowel disease-associated risk loci.

Increased Intestinal Microbial Diversity Following Fecal Microbiota Transplant for Active Crohn's Disease.

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.

Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease.

SIKs control osteocyte responses to parathyroid hormone.

Vedolizumab Therapy Is Associated with an Improvement in Sleep Quality and Mood in Inflammatory Bowel Diseases.

RNF166 Determines Recruitment of Adaptor Proteins during Antibacterial Autophagy.

Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity.

Host and Environmental Factors Influencing Individual Human Cytokine Responses.

A Functional Genomics Approach to Understand Variation in Cytokine Production in Humans.

Differential Effects of Environmental and Genetic Factors on T and B Cell Immune Traits.

Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity.

Visceral Adiposity, Genetic Susceptibility, and Risk of Complications Among Individuals with Crohn's Disease.

TMEM258 Is a Component of the Oligosaccharyltransferase Complex Controlling ER Stress and Intestinal Inflammation.

Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity.

The Csk-Associated Adaptor PAG Inhibits Effector T Cell Activation in Cooperation with Phosphatase PTPN22 and Dok Adaptors.

The Role of the Histone Methyltransferase Enhancer of Zeste Homolog 2 (EZH2) in the Pathobiological Mechanisms Underlying Inflammatory Bowel Disease (IBD).

The Ubiquitin Ligase Smurf1 Functions in Selective Autophagy of Mycobacterium tuberculosis and Anti-tuberculous Host Defense.

Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study.

A Microbiome Foundation for the Study of Crohn's Disease.

Maintenance of macrophage transcriptional programs and intestinal homeostasis by epigenetic reader SP140.

Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease.

Gut Microbiome Function Predicts Response to Anti-integrin Biologic Therapy in Inflammatory Bowel Diseases.

Epitope-specific immunotherapy targeting CD4-positive T cells in coeliac disease: two randomised, double-blind, placebo-controlled phase 1 studies.

Selective Induction of Homeostatic Th17 Cells in the Murine Intestine by Cholera Toxin Interacting with the Microbiota.

Dissecting the human microbiome with single-cell genomics.

E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP.

Fine-mapping inflammatory bowel disease loci to single-variant resolution.

Indoleacrylic Acid Produced by Commensal Peptostreptococcus Species Suppresses Inflammation.

Intestinal virome changes precede autoimmunity in type I diabetes-susceptible children.

Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine.

Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells.

Human genetic variation and the gut microbiome in disease.

SHANK3 Regulates Intestinal Barrier Function Through Modulating ZO-1 Expression Through the PKCε-dependent Pathway.

The Ubiquitin Ligase Smurf1 Functions in Selective Autophagy of Mycobacterium tuberculosis and Anti-tuberculous Host Defense.

Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9.

Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammation.

SHANK3 Regulates Intestinal Barrier Function Through Modulating ZO-1 Expression Through the PKCε-dependent Pathway.

Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease.

p40 (phox) -Deficient Mice Exhibit Impaired Bacterial Clearance and Enhanced Pro-inflammatory Responses during Salmonella enterica serovar Typhimurium Infection.

Transcription factor TFEB cell-autonomously modulates susceptibility to intestinal epithelial cell injury in vivo.

A role for bacterial urease in gut dysbiosis and Crohn's disease.

A single-cell survey of the small intestinal epithelium.

Mechanisms and Function of Autophagy in Intestinal Disease.

Difference in clinical course, genetics, and the microbiome between familial and sporadic inflammatory bowel diseases.

A novel Ruminococcus gnavus clade enriched in inflammatory bowel disease patients.

Dynamics of metatranscription in the inflammatory bowel disease gut microbiome.

Genomic and expression analyses identify a disease modifying variant for fibrostenotic Crohn's disease.

Loss of Response to Anti-Tumor Necrosis Factor Alpha Therapy in Crohn's Disease Is Not Associated with Emergence of Novel Inflammatory Pathways.

Host genetic variation and its microbiome interactions within the Human Microbiome Project.

Strain Tracking Reveals the Determinants of Bacterial Engraftment in the Human Gut Following Fecal Microbiota Transplantation.

C1orf106 is a colitis risk gene that regulates stability of epithelial adherens junctions.

A common mechanism links activities of butyrate in the colon.

Without Adaptive Immunity, There's a Cost to Responding STAT.

Genetic Markers Predict Primary Nonresponse and Durable Response to Anti-Tumor Necrosis Factor Therapy in Ulcerative Colitis.

Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses.

Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population.

The causes and consequences of variation in human cytokine production in health.

Nitric Oxide Engages an Anti-inflammatory Feedback Loop Mediated by Peroxiredoxin 5 in Phagocytes.

Strain-Level Analysis of Mother-to-Child Bacterial Transmission during the First Few Months of Life.

Impaired Aryl Hydrocarbon Receptor Ligand Production by the Gut Microbiota Is a Key Factor in Metabolic Syndrome.

TMEM41B is a novel regulator of autophagy and lipid mobilization.

Salt-Inducible Kinases: Physiology, Regulation by cAMP, and Therapeutic Potential.

Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course.

Antigen discovery and specification of immunodominance hierarchies for MHCII-restricted epitopes.

The human gut microbiome in early-onset type 1 diabetes from the TEDDY study.

T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation.