Publications for All Faculty
Translation elongation defects activate the Caenorhabditis elegans ZIP-2 bZIP transcription factor-mediated toxin defense.
Decreased SynMuv B gene activity in response to viral infection leads to activation of the antiviral RNAi pathway in C. elegans.
Prenatal maternal infection promotes maternal microchimeric cells to alter infection risk in male offspring.
Hydrogen sulfide mediates the interaction between C. elegans and Actinobacteria from its natural microbial environment.
Development of an FKBP12-recruiting chemical-induced proximity DNA-encoded library and its application to discover an autophagy potentiator.
Discovery of a Pseudomonas aeruginosa-specific small molecule targeting outer membrane protein OprH-LPS interaction by a multiplexed screen.
ABA-activated low-nanomolar Ca2+-CPK signalling controls root cap cycle plasticity and stress adaptation.
Spatially restricted immune and microbiota-driven adaptation of the gut.
Chemical tools to expand the ligandable proteome: Diversity-oriented synthesis-based photoreactive stereoprobes.
Perturbation-specific transcriptional mapping for unbiased target elucidation of antibiotics.
Commensal consortia decolonize Enterobacteriaceae via ecological control.
Polymeric Nanocarriers Autonomously Cross the Plant Cell Wall and Enable Protein Delivery for Stress Sensing.
Determination of chlorothalonil in vegetables/fruits using liquid chromatography-tandem mass spectrometry with a discharge adapter interface.
Emerging biochemical, microbial and immunological evidence in the search for why HLA-B∗27 confers risk for spondyloarthritis.
B cell tolerance and autoimmunity: Lessons from repertoires.
Small-molecule probe for IBD risk variant GPR65 I231L alters cytokine signaling networks through positive allosteric modulation.
Caenorhabditis elegans SynMuv B gene activity is down-regulated during a viral infection to enhance RNA interference.
Mutations in nucleotide metabolism genes bypass proteasome defects in png-1/NGLY1-deficient Caenorhabditis elegans.
The centrosomal protein FGFR1OP controls myosin function in murine intestinal epithelial cells.
3-Hydroxykynurenine targets kainate receptors to promote defense against infection.
Discovery of disease-adapted bacterial lineages in inflammatory bowel diseases.
CMTR-1 RNA methyltransferase mutations activate widespread expression of a dopaminergic neuron-specific mitochondrial complex I gene.
Perturbation-Specific Transcriptional Mapping facilitates unbiased target elucidation of antibiotics.
An esophagus cell atlas reveals dynamic rewiring during active eosinophilic esophagitis and remission.
Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension.
