• Xie F, Dai S, Zhao Y, Huang P, Yu S, Ren B, Wang Q, Ji Z, Alterovitz G, Zhang Q, Zhang J, Chen X, Jiang L, Song F, Liu H, Ausubel FM, Liu X, Dai H, Zhang L Generation of Fluorinated Amychelin Siderophores against Pseudomonas aeruginosa Infections by a Combination of Genome Mining and Mutasynthesis. Cell Chem Biol. 2020;27(12):1532-1543.e6 - PMID: 33186541 - DOI: 10.1016/j.chembiol.2020.10.009

  • Lee K, Escobar I, Jang Y, Kim W, Ausubel FM, Mylonakis E In the Model Host Caenorhabditis elegans, Sphingosine-1-Phosphate-Mediated Signaling Increases Immunity toward Human Opportunistic Bacteria. Int J Mol Sci. 2020;21(21):ePub - PMID: 33105563 - PMCID: PMC7672543 - DOI: 10.3390/ijms21217813

  • Khader R, Tharmalingam N, Mishra B, Felix L, Ausubel FM, Kelso MJ, Mylonakis E Characterization of Five Novel Anti-MRSA Compounds Identified Using a Whole-Animal Caenorhabditis elegans/Galleria mellonella Sequential-Screening Approach. Antibiotics (Basel). 2020;9(8):ePub - PMID: 32726955 - PMCID: PMC7459823 - DOI: 10.3390/antibiotics9080449

  • Kim W, Zou G, Pan W, Fricke N, Faizi HA, Kim SM, Khader R, Li S, Lee K, Escorba I, Vlahovska PM, Gao H, Ausubel FM, Mylonakis E The Neutrally Charged Diarylurea Compound PQ401 Kills Antibiotic-Resistant and Antibiotic-Tolerant Staphylococcus aureus. MBio. 2020;11(3):ePub - PMID: 32605985 - PMCID: PMC7327171 - DOI: 10.1128/mBio.01140-20

  • Vasquez-Rifo A, Veksler-Lublinsky I, Cheng Z, Ausubel FM, Ambros V The Pseudomonas aeruginosa accessory genome elements influence virulence towards Caenorhabditis elegans. Genome Biol. 2019;20(1):270 - PMID: 31823826 - PMCID: PMC6902481 - DOI: 10.1186/s13059-019-1890-1

  • Kim W, Zou G, Hari TPA, Wilt IK, Zhu W, Galle N, Faizi HA, Hendricks GL, Tori K, Pan W, Huang X, Steele AD, Csatary EE, Dekarske MM, Rosen JL, Ribeiro NQ, Lee K, Port J, Fuchs BB, Vlahovska PM, Wuest WM, Gao H, Ausubel FM, Mylonakis E A selective membrane-targeting repurposed antibiotic with activity against persistent methicillin-resistant Staphylococcus aureus. Proc Natl Acad Sci U S A. 2019;116(33):16529-16534 - PMID: 31358625 - PMCID: PMC6697817 - DOI: 10.1073/pnas.1904700116

  • Ausubel FM Tracing My Roots: How I Became a Plant Biologist. Annu Rev Genet. 2018;52:1-20 - PMID: 30192637 - DOI: 10.1146/annurev-genet-120417-031722

  • Kim W, Steele AD, Zhu W, Csatary EE, Fricke N, Dekarske MM, Jayamani E, Pan W, Kwon B, Sinitsa IF, Rosen JL, Conery AL, Fuchs BB, Vlahovska PM, Ausubel FM, Gao H, Wuest WM, Mylonakis E Discovery and Optimization of nTZDpa as an Antibiotic Effective Against Bacterial Persisters. ACS Infect Dis. 2018;4(11):1540-1545 - PMID: 30132650 - PMCID: PMC6468991 - DOI: 10.1021/acsinfecdis.8b00161

  • Kim W, Zhu W, Hendricks GL, Van Tyne D, Steele AD, Keohane CE, Fricke N, Conery AL, Shen S, Pan W, Lee K, Rajamuthiah R, Fuchs BB, Vlahovska PM, Wuest WM, Gilmore MS, Gao H, Ausubel FM, Mylonakis E A new class of synthetic retinoid antibiotics effective against bacterial persisters. Nature. 2018;556(7699):103-107 - PMID: 29590091 - PMCID: PMC6462414 - DOI: 10.1038/nature26157

  • Haller S, Franchet A, Hakkim A, Chen J, Drenkard E, Yu S, Schirmeier S, Li Z, Martins N, Ausubel FM, Liégeois S, Ferrandon D Quorum-sensing regulator RhlR but not its autoinducer RhlI enablesPseudomonasto evade opsonization. EMBO Rep. 2018;19(5):ePub - PMID: 29523648 - PMCID: PMC5934776 - DOI: 10.15252/embr.201744880

  • Yuen GJ, Ausubel FM Both live and dead Enterococci activate Caenorhabditis elegans host defense via immune and stress pathways. Virulence. 2018;9(1):0 - PMID: 29436902 - PMCID: PMC5955442 - DOI: 10.1080/21505594.2018.1438025

  • Koeva M, Gutu AD, Hebert W, Wager JD, Yonker LM, O'Toole GA, Ausubel FM, Moskowitz SM, Joseph-McCarthy D An Anti-Persister Strategy for the Treatment of Chronic Pseudomonas aeruginosa Infections. Antimicrob Agents Chemother. 2017;61(12):ePub - PMID: 28923873 - PMCID: PMC5700368 - DOI: 10.1128/AAC.00987-17

  • Cezairliyan B, Ausubel FM Investment in secreted enzymes during nutrient-limited growth is utility dependent. Proc Natl Acad Sci U S A. 2017;114(37):E7796-E7802 - PMID: 28847943 - PMCID: PMC5604031 - DOI: 10.1073/pnas.1708580114

  • Jayamani E, Tharmalingam N, Rajamuthiah R, Coleman JJ, Kim W, Okoli I, Hernandez AM, Lee K, Nau GJ, Ausubel FM, Mylonakis E Characterization of a Francisella tularensis-Caenorhabditis elegans pathosystem for the evaluation of therapeutic compounds. Antimicrob Agents Chemother. 2017;61(9):ePub - PMID: 28652232 - PMCID: PMC5571314 - DOI: 10.1128/AAC.00310-17

  • Urbach JM, Ausubel FM The NBS-LRR architectures of plant R-proteins and metazoan NLRs evolved in independent events. Proc Natl Acad Sci U S A. 2017;114(5):1063-1068 - PMID: 28096345 - PMCID: PMC5293065 - DOI: 10.1073/pnas.1619730114

  • Gregory KE, Samuel BS, Houghteling P, Shan G, Ausubel FM, Sadreyev RI, Walker WA Influence of maternal breast milk ingestion on acquisition of the intestinal microbiome in preterm infants. Microbiome. 2016;4(1):68 - PMID: 28034306 - PMCID: PMC5200970 - DOI: 10.1186/s40168-016-0214-x

  • McEwan DL, Feinbaum RL, Stroustrup N, Haas W, Conery AL, Anselmo A, Sadreyev R, Ausubel FM Tribbles ortholog NIPI-3 and bZIP transcription factor CEBP-1 regulate a Caenorhabditis elegans intestinal immune surveillance pathway. BMC Biol. 2016;14(1):105 - PMID: 27927200 - PMCID: PMC5143455 - DOI: 10.1186/s12915-016-0334-6

  • Newman M, Ausubel FM Introduction to Gene Editing and Manipulation Using CRISPR/Cas9 Technology. Curr Protoc Mol Biol. 2016;115:31.4.1-6 - PMID: 27366890 - PMCID: PMC4963815 - DOI: 10.1002/cpmb.14

  • Liu S, Bartnikas LM, Volko SM, Ausubel FM, Tang D Mutation of the Glucosinolate Biosynthesis Enzyme Cytochrome P450 83A1 Monooxygenase Increases Camalexin Accumulation and Powdery Mildew Resistance. Front Plant Sci. 2016;7:227 - PMID: 26973671 - PMCID: PMC4774424 - DOI: 10.3389/fpls.2016.00227

  • Kim W, Fricke N, Conery AL, Fuchs BB, Rajamuthiah R, Jayamani E, Vlahovska PM, Ausubel FM, Mylonakis E NH125 kills methicillin-resistant Staphylococcus aureus persisters by lipid bilayer disruption. Future Med Chem. 2016;8(3):257-69 - PMID: 26910612 - PMCID: PMC4976882 - DOI: 10.4155/fmc.15.189

  • Dolla NK, Chen C, Larkins-Ford J, Rajamuthiah R, Jagadeesan S, Conery AL, Ausubel FM, Mylonakis E, Bremner JB, Lewis K, Kelso MJ On the Mechanism of Berberine-INF55 (5-Nitro-2-phenylindole) Hybrid Antibacterials. Aust J Chem. 2016;67:1471-1480 - PMID: 26806960 - PMCID: PMC4720975 - DOI: 10.1071/CH14426

  • Rajamuthiah R, Jayamani E, Majed H, Conery AL, Kim W, Kwon B, Fuchs BB, Kelso MJ, Ausubel FM, Mylonakis E Antibacterial properties of 3-(phenylsulfonyl)-2-pyrazinecarbonitrile. Bioorg Med Chem Lett. 2015;25(22):5203-7 - PMID: 26459212 - PMCID: PMC4718707 - DOI: 10.1016/j.bmcl.2015.09.066

  • Cervone F, Ausubel FM, Lorenzo G Enhancing immunity by engineering DAMPs. Oncotarget. 2015;6(30):28523-4 - PMID: 26387132 - PMCID: PMC4745668 - DOI: 10.18632/oncotarget.5251

  • Haney CH, Ausubel FM MICROBIOME. Plant microbiome blueprints. Science. 2015;349(6250):788-9 - PMID: 26293938 - DOI: 10.1126/science.aad0092

  • Groen SC, Humphrey PT, Chevasco D, Ausubel FM, Pierce NE, Whiteman NK Pseudomonas syringae enhances herbivory by suppressing the reactive oxygen burst in Arabidopsis. J Insect Physiol. 2016;84:90-102 - PMID: 26205072 - PMCID: PMC4721946 - DOI: 10.1016/j.jinsphys.2015.07.011

  • Rajamuthiah R, Jayamani E, Conery AL, Fuchs BB, Kim W, Johnston T, Vilcinskas A, Ausubel FM, Mylonakis E A Defensin from the Model Beetle Tribolium castaneum Acts Synergistically with Telavancin and Daptomycin against Multidrug Resistant Staphylococcus aureus. PLoS One. 2015;10(6):e0128576 - PMID: 26062137 - PMCID: PMC4465704 - DOI: 10.1371/journal.pone.0128576

  • Kim W, Conery AL, Rajamuthiah R, Fuchs BB, Ausubel FM, Mylonakis E Identification of an Antimicrobial Agent Effective against Methicillin-Resistant Staphylococcus aureus Persisters Using a Fluorescence-Based Screening Strategy. PLoS One. 2015;10(6):e0127640 - PMID: 26039584 - PMCID: PMC4454602 - DOI: 10.1371/journal.pone.0127640

  • Haney CH, Samuel BS, Bush J, Ausubel FM Associations with rhizosphere bacteria can confer an adaptive advantage to plants. Nat Plants. 2015;1(6):ePub - PMID: 27019743 - PMCID: PMC4806546 - DOI: 10.1038/nplants.2015.51

  • Haney CH, Samuel BS, Bush J, Ausubel FM Associations with rhizosphere bacteria can confer an adaptive advantage to plants. Nat Plants. 2015;1:15051 - PMID: 27250003

  • Zhang XC, Millet YA, Cheng Z, Bush J, Ausubel FM Jasmonate signalling in Arabidopsis involves SGT1b-HSP70-HSP90 chaperone complexes. Nat Plants. 2015;1:ePub - PMID: 27054042 - PMCID: PMC4819967 - DOI: 10.1038/nplants.2015.49

  • Rajamuthiah R, Fuchs BB, Conery AL, Kim W, Jayamani E, Kwon B, Ausubel FM, Mylonakis E Repurposing Salicylanilide Anthelmintic Drugs to Combat Drug Resistant Staphylococcus aureus. PLoS One. 2015;10(4):e0124595 - PMID: 25897961 - PMCID: PMC4405337 - DOI: 10.1371/journal.pone.0124595

  • Benedetti M, Pontiggia D, Raggi S, Cheng Z, Scaloni F, Ferrari S, Ausubel FM, Cervone F, De Lorenzo G Plant immunity triggered by engineered in vivo release of oligogalacturonides, damage-associated molecular patterns. Proc Natl Acad Sci U S A. 2015;112(17):5533-8 - PMID: 25870275 - PMCID: PMC4418913 - DOI: 10.1073/pnas.1504154112

  • Cheng Z, Li JF, Niu Y, Zhang XC, Woody OZ, Xiong Y, Djonovi? S, Millet Y, Bush J, McConkey BJ, Sheen J, Ausubel FM Pathogen-secreted proteases activate a novel plant immune pathway. Nature. 2015;521(7551):213-6 - PMID: 25731164 - PMCID: PMC4433409 - DOI: 10.1038/nature14243

  • Iscla I, Wray R, Blount P, Larkins-Ford J, Conery AL, Ausubel FM, Ramu S, Kavanagh A, Huang JX, Blaskovich MA, Cooper MA, Obregon-Henao A, Orme I, Tjandra ES, Stroeher UH, Brown MH, Macardle C, van Holst N, Ling Tong C, Slattery AD, Gibson CT, Raston CL, Boulos RA A new antibiotic with potent activity targets MscL. J Antibiot (Tokyo). 2015;68(7):453-62 - PMID: 25649856 - PMCID: PMC4430313 - DOI: 10.1038/ja.2015.4

  • Kirienko NV, Ausubel FM, Ruvkun G Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa. Proc Natl Acad Sci U S A. 2015;112(6):1821-6 - PMID: 25624506 - PMCID: PMC4330731 - DOI: 10.1073/pnas.1424954112

  • Jayamani E, Rajamuthiah R, Larkins-Ford J, Fuchs BB, Conery AL, Vilcinskas A, Ausubel FM, Mylonakis E Insect-derived Cecropins Display Activity Against Acinetobacter baumannii in a Whole-Animal High-Throughput Caenorhabditis elegans Model. Antimicrob Agents Chemother. 2015;59(3):1728-37 - PMID: 25583713 - PMCID: PMC4325797 - DOI: 10.1128/AAC.04198-14

  • Zhang XC, Millet Y, Ausubel FM, Borowsky M Next-Gen Sequencing-Based Mapping and Identification of Ethyl Methanesulfonate-Induced Mutations in Arabidopsis thaliana. Curr Protoc Mol Biol. 2014;108:7.18.1-16 - PMID: 25271717 - DOI: 10.1002/0471142727.mb0718s108

  • Ausubel FM Twists and turns: my career path and concerns about the future. Genetics. 2014;198(2):431-4 - PMID: 25316778 - PMCID: PMC4196596 - DOI: 10.1534/genetics.114.169102

  • Mammarella ND, Cheng Z, Fu ZQ, Daudi A, Bolwell GP, Dong X, Ausubel FM Apoplastic peroxidases are required for salicylic acid-mediated defense against Pseudomonas syringae. Phytochemistry. 2015;112:110-121 - PMID: 25096754 - PMCID: PMC4314520 - DOI: 10.1016/j.phytochem.2014.07.010

  • Pukkila-Worley R, Feinbaum RL, McEwan DL, Conery AL, Ausubel FM The Evolutionarily Conserved Mediator Subunit MDT-15/MED15 Links Protective Innate Immune Responses and Xenobiotic Detoxification. PLoS Pathog. 2014;10(5):e1004143 - PMID: 24875643 - PMCID: PMC4038581 - DOI: 10.1371/journal.ppat.1004143

  • Kirienko NV, Cezairliyan BO, Ausubel FM, Powell JR Pseudomonas aeruginosa PA14 Pathogenesis in Caenorhabditis elegans. Methods Mol Biol. 2014;1149:653-69 - PMID: 24818940 - DOI: 10.1007/978-1-4939-0473-0_50

  • Conery AL, Larkins-Ford J, Ausubel FM, Kirienko NV High-Throughput Screening for Novel Anti-Infectives Using a C. elegans Pathogenesis Model. Curr Protoc Chem Biol. 2014;6(1):25-37 - PMID: 24652621 - PMCID: PMC4021578 - DOI: 10.1002/9780470559277.ch130160

  • Yuen GJ, Ausubel FM Enterococcus infection biology: Lessons from invertebrate host models. J Microbiol. 2014;52(3):200-10 - PMID: 24585051 - PMCID: PMC4556283 - DOI: 10.1007/s12275-014-4011-6

  • Rajamuthiah R, Fuchs BB, Jayamani E, Kim Y, Larkins-Ford J, Conery A, Ausubel FM, Mylonakis E Whole Animal Automated Platform for Drug Discovery against Multi-Drug Resistant Staphylococcus aureus. PLoS One. 2014;9(2):e89189 - PMID: 24586584 - PMCID: PMC3929655 - DOI: 10.1371/journal.pone.0089189

  • Groen SC, Whiteman NK, Bahrami AK, Wilczek AM, Cui J, Russell JA, Cibrian-Jaramillo A, Butler IA, Rana JD, Huang GH, Bush J, Ausubel FM, Pierce NE Pathogen-Triggered Ethylene Signaling Mediates Systemic-Induced Susceptibility to Herbivory in Arabidopsis. Plant Cell. 2013;25(11):4755-66 - PMID: 24285796 - PMCID: PMC3875748 - DOI: 10.1105/tpc.113.113415

  • Ausubel FM Virulence profile: Frederick M Ausubel. Virulence. 2013;4(8):730-3 - PMID: 24481134 - PMCID: PMC3925705 - DOI: 10.4161/viru.26579

  • Kirienko NV, Kirienko DR, Larkins-Ford J, Wählby C, Ruvkun G, Ausubel FM Pseudomonas aeruginosa Disrupts Caenorhabditis elegans Iron Homeostasis, Causing a Hypoxic Response and Death. Cell Host Microbe. 2013;13(4):406-16 - PMID: 23601103 - PMCID: PMC3641844 - DOI: 10.1016/j.chom.2013.03.003

  • Kirienko NV, Kirienko DR, Larkins-Ford J, Wählby C, Ruvkun G, Ausubel FM Pseudomonas aeruginosa Disrupts Caenorhabditis elegans Iron Homeostasis, Causing a Hypoxic Response and Death. Cell Host Microbe. 2013;13(4):406-16 - PMID: 23601103 - PMCID: PMC3641844 - DOI: 10.1016/j.chom.2013.03.003

  • Djonovi? S, Urbach JM, Drenkard E, Bush J, Feinbaum R, Ausubel JL, Traficante D, Risech M, Kocks C, Fischbach MA, Priebe GP, Ausubel FM Trehalose biosynthesis promotes Pseudomonas aeruginosa pathogenicity in plants. PLoS Pathog. 2013;9(3):e1003217 - PMID: 23505373 - PMCID: PMC3591346 - DOI: 10.1371/journal.ppat.1003217

  • Cezairliyan B, Vinayavekhin N, Grenfell-Lee D, Yuen GJ, Saghatelian A, Ausubel FM Identification of Pseudomonas aeruginosa Phenazines that Kill Caenorhabditis elegans. PLoS Pathog. 2013;9(1):e1003101 - PMID: 23300454 - PMCID: PMC3536714 - DOI: 10.1371/journal.ppat.1003101

  • Danna CH, Zhang XC, Khatri A, Bent AF, Ronald PC, Ausubel FM FLS2-Mediated Responses to Ax21-Derived Peptides: Response to the Mueller et al. Commentary. Plant Cell. 2012;24(8):3174-6 - PMID: 22923675 - PMCID: PMC3462622 - DOI: 10.1105/tpc.112.099275

  • Feinbaum RL, Urbach JM, Liberati NT, Djonovic S, Adonizio A, Carvunis AR, Ausubel FM Genome-Wide Identification of Pseudomonas aeruginosa Virulence-Related Genes Using a Caenorhabditis elegans Infection Model. PLoS Pathog. 2012;8(7):e1002813 - PMID: 22911607 - PMCID: PMC3406104 - DOI: 10.1371/journal.ppat.1002813

  • Whiteman NK, Gloss AD, Sackton TB, Groen SC, Humphrey PT, Lapoint RT, Sønderby IE, Halkier BA, Kocks C, Ausubel FM, Pierce NE Genes Involved in the Evolution of Herbivory By A Leaf-Mining, Drosophilid Fly. Genome Biol Evol. 2012;4(9):900-16 - PMID: 22813779 - PMCID: PMC3516228 - DOI: 10.1093/gbe/evs063

  • Yao Y, Danna CH, Ausubel FM, Kovalchuk I Perception of volatiles produced by UVC-irradiated plants alters the response to viral infection in naïve neighboring plants. Plant Signal Behav. 2012;7(7):741-5 - PMID: 22751319 - PMCID: PMC3583953 - DOI: 10.4161/psb.20406

  • Pukkila-Worley R, Feinbaum R, Kirienko NV, Larkins-Ford J, Conery AL, Ausubel FM Stimulation of Host Immune Defenses by a Small Molecule Protects C. elegans from Bacterial Infection. PLoS Genet. 2012;8(6):e1002733 - PMID: 22719261 - PMCID: PMC3375230 - DOI: 10.1371/journal.pgen.1002733

  • Wählby C, Kamentsky L, Liu ZH, Riklin-Raviv T, Conery AL, O'Rourke EJ, Sokolnicki KL, Visvikis O, Ljosa V, Irazoqui JE, Golland P, Ruvkun G, Ausubel FM, Carpenter AE An image analysis toolbox for high-throughput C. elegans assays. Nat Methods. 2012;9(7):714-6 - PMID: 22522656 - PMCID: PMC3433711 - DOI: 10.1038/nmeth.1984

  • McEwan DL, Kirienko NV, Ausubel FM Host Translational Inhibition by Pseudomonas aeruginosa Exotoxin A Triggers an Immune Response in Caenorhabditis elegans. Cell Host Microbe. 2012;11(4):364-74 - PMID: 22520464 - PMCID: PMC3334877 - DOI: 10.1016/j.chom.2012.02.007

  • O'Brien JA, Daudi A, Finch P, Butt VS, Whitelegge JP, Souda P, Ausubel FM, Bolwell GP A Peroxidase-Dependent Apoplastic Oxidative Burst in Cultured Arabidopsis Cells Functions in MAMP-Elicited Defense. Plant Physiol. 2012;158(4):2013-27 - PMID: 22319074 - PMCID: PMC3320203 - DOI: 10.1104/pp.111.190140

  • Daudi A, Cheng Z, O'Brien JA, Mammarella N, Khan S, Ausubel FM, Bolwell GP The apoplastic oxidative burst peroxidase in Arabidopsis is a major component of pattern-triggered immunity. Plant Cell. 2012;24(1):275-87 - PMID: 22247251 - PMCID: PMC3289579 - DOI: 10.1105/tpc.111.093039

  • Pukkila-Worley R, Ausubel FM Immune defense mechanisms in the Caenorhabditis elegans intestinal epithelium. Curr Opin Immunol. 2012;24(1):3-9 - PMID: 22236697 - PMCID: PMC3660727 - DOI: 10.1016/j.coi.2011.10.004

  • Yao Y, Danna CH, Zemp FJ, Titov V, Ciftci ON, Przybylski R, Ausubel FM, Kovalchuk I UV-C-irradiated Arabidopsis and tobacco emit volatiles that trigger genomic instability in neighboring plants. Plant Cell. 2011;23(10):3842-52 - PMID: 22028460 - PMCID: PMC3229153 - DOI: 10.1105/tpc.111.089003

  • Limmer S, Haller S, Drenkard E, Lee J, Yu S, Kocks C, Ausubel FM, Ferrandon D Pseudomonas aeruginosa RhlR is required to neutralize the cellular immune response in a Drosophila melanogaster oral infection model. Proc Natl Acad Sci U S A. 2011;108(42):17378-83 - PMID: 21987808 - PMCID: PMC3198323 - DOI: 10.1073/pnas.1114907108

  • Slatko BE, Kieleczawa J, Ju J, Gardner AF, Hendrickson CL, Ausubel FM automated DNA sequencing technology. Curr Protoc Mol Biol. 2011;Chapter 7:Unit7.2 - PMID: 21987057 - DOI: 10.1002/0471142727.mb0702s96

  • Pukkila-Worley R, Ausubel FM, Mylonakis E Candida albicans infection of Caenorhabditis elegans induces antifungal immune defenses. PLoS Pathog. 2011;7(6):e1002074 - PMID: 21731485 - PMCID: PMC3121877 - DOI: 10.1371/journal.ppat.1002074

  • Danna CH, Millet YA, Koller T, Han SW, Bent AF, Ronald PC, Ausubel FM The Arabidopsis flagellin receptor FLS2 mediates the perception of Xanthomonas Ax21 secreted peptides. Proc Natl Acad Sci U S A. 2011;108(22):9286-91 - PMID: 21576467 - PMCID: PMC3107323 - DOI: 10.1073/pnas.1106366108

  • Gopalan S, Ausubel FM A high throughput amenable Arabidopsis-P. aeruginosa system reveals a rewired regulatory module and the utility to identify potent anti-infectives. PLoS One. 2011;6(1):e16381 - PMID: 21283656 - PMCID: PMC3025032 - DOI: 10.1371/journal.pone.0016381

  • Raviv TR, Ljosa V, Conery AL, Ausubel FM, Carpenter AE, Golland P, Wählby C Morphology-guided graph search for untangling objects: C. elegans analysis. Med Image Comput Comput Assist Interv. 2010;13(Pt 3):634-41 - PMID: 20879454 - PMCID: PMC3050593 - DOI: 10.1007/978-3-642-15711-0_79

  • Irazoqui JE, Troemel ER, Feinbaum RL, Luhachack LG, Cezairliyan BO, Ausubel FM Distinct pathogenesis and host responses during infection of C. elegans by P. aeruginosa and S. aureus. PLoS Pathog. 2010;6:e1000982 - PMID: 20617181 - PMCID: PMC2895663 - DOI: 10.1371/journal.ppat.1000982

  • Wählby C, Riklin-Raviv T, Ljosa V, Conery AL, Golland P, Ausubel FM, Carpenter AE RESOLVING CLUSTERED WORMS VIA PROBABILISTIC SHAPE MODELS. Proc IEEE Int Symp Biomed Imaging. 2010;2010(14-17 April 2010):552-555 - PMID: 21383863 - PMCID: PMC3048333 - DOI: 10.1109/ISBI.2010.5490286

  • Tomkiewicz D, Casadei G, Larkins-Ford J, Moy TI, Garner J, Bremner JB, Ausubel FM, Lewis K, Kelso MJ Berberine-INF55 (5-nitro-2-phenylindole) hybrid antimicrobials: effects of varying the relative orientation of the berberine and INF55 components. Antimicrob Agents Chemother. 2010;54(8):3219-24 - PMID: 20498327 - PMCID: PMC2916310 - DOI: 10.1128/AAC.01715-09

  • Irazoqui JE, Ausubel FM 99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: Caenorhabditis elegans as a model to study tissues involved in host immunity and microbial pathogenesis. Clin Exp Immunol. 2010;160(1):48-57 - PMID: 20415851 - PMCID: PMC2841835 - DOI: 10.1111/j.1365-2249.2010.04122.x

  • Millet YA, Danna CH, Clay NK, Songnuan W, Simon MD, Werck-Reichhart D, Ausubel FM Innate immune responses activated in Arabidopsis roots by microbe-associated molecular patterns. Plant Cell. 2010;22(3):973-90 - PMID: 20348432 - PMCID: PMC2861455 - DOI: 10.1105/tpc.109.069658

  • Estes KA, Dunbar TL, Powell JR, Ausubel FM, Troemel ER bZIP transcription factor zip-2 mediates an early response to Pseudomonas aeruginosa infection in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2010;107(5):2153-8 - PMID: 20133860 - PMCID: PMC2836710 - DOI: 10.1073/pnas.0914643107

  • Irazoqui JE, Urbach JM, Ausubel FM Evolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebrates. Nat Rev Immunol. 2010;10(1):47-58 - PMID: 20029447 - PMCID: PMC2965059 - DOI: 10.1038/nri2689

  • Okoli I, Coleman JJ, Tampakakis E, Tempakakis E, An WF, Holson E, Wagner F, Conery AL, Larkins-Ford J, Wu G, Stern A, Ausubel FM, Mylonakis E Identification of antifungal compounds active against Candida albicans using an improved high-throughput Caenorhabditis elegans assay. PLoS One. 2009;4(9):e7025 - PMID: 19750012 - PMCID: PMC2737148 - DOI: 10.1371/journal.pone.0007025

  • Moy TI, Conery AL, Larkins-Ford J, Wu G, Mazitschek R, Casadei G, Lewis K, Carpenter AE, Ausubel FM High-throughput screen for novel antimicrobials using a whole animal infection model. ACS Chem Biol. 2009;4(7):527-33 - PMID: 19572548 - PMCID: PMC2745594 - DOI: 10.1021/cb900084v

  • Urbach JM, Wei T, Liberati N, Grenfell-Lee D, Villanueva J, Wu G, Ausubel FM Using PATIMDB to create bacterial transposon insertion mutant libraries. Curr Protoc Mol Biol. 2009;Chapter 19:Unit 19.7 - PMID: 19343706 - PMCID: PMC4492697 - DOI: 10.1002/0471142727.mb1907s86

  • Powell JR, Kim DH, Ausubel FM The G protein-coupled receptor FSHR-1 is required for the Caenorhabditis elegans innate immune response. Proc Natl Acad Sci U S A. 2009;106(8):2782-7 - PMID: 19196974 - PMCID: PMC2650343 - DOI: 10.1073/pnas.0813048106

  • Chandran D, Tai YC, Hather G, Dewdney J, Denoux C, Burgess DG, Ausubel FM, Speed TP, Wildermuth MC Temporal global expression data reveal known and novel salicylate-impacted processes and regulators mediating powdery mildew growth and reproduction on Arabidopsis. Plant Physiol. 2009;149(3):1435-51 - PMID: 19176722 - PMCID: PMC2649394 - DOI: 10.1104/pp.108.132985

  • Gopalan S, Ausubel FM A metasystem of framework model organisms to study emergence of new host-microbe adaptations. PLoS One. 2008;3(12):e3891 - PMID: 19066631 - PMCID: PMC2588659 - DOI: 10.1371/journal.pone.0003891

  • Troemel ER, Félix MA, Whiteman NK, Barrière A, Ausubel FM Microsporidia are natural intracellular parasites of the nematode Caenorhabditis elegans. PLoS Biol. 2008;6(12):2736-52 - PMID: 19071962 - PMCID: PMC2596862 - DOI: 10.1371/journal.pbio.0060309

  • Irazoqui JE, Ng A, Xavier RJ, Ausubel FM Role for beta-catenin and HOX transcription factors in Caenorhabditis elegans and mammalian host epithelial-pathogen interactions. Proc Natl Acad Sci U S A. 2008;105(45):17469-74 - PMID: 18981407 - PMCID: PMC2582251 - DOI: 10.1073/pnas.0809527105

  • Galletti R, Denoux C, Gambetta S, Dewdney J, Ausubel FM, De Lorenzo G, Ferrari S The AtrbohD-mediated oxidative burst elicited by oligogalacturonides in Arabidopsis is dispensable for the activation of defense responses effective against Botrytis cinerea. Plant Physiol. 2008;148(3):1695-706 - PMID: 18790995 - PMCID: PMC2577270 - DOI: 10.1104/pp.108.127845

  • Adonizio A, Leal SM, Ausubel FM, Mathee K Attenuation of Pseudomonas aeruginosa virulence by medicinal plants in a Caenorhabditis elegans model system. J Med Microbiol. 2008;57(Pt 7):809-813 - PMID: 18566137 - DOI: 10.1099/jmm.0.47802-0

  • Lemaitre B, Ausubel FM Animal models for host-pathogen interactions. Curr Opin Microbiol. 2008;11(3):249-50 - PMID: 18539076 - DOI: 10.1016/j.mib.2008.05.002

  • Denoux C, Galletti R, Mammarella N, Gopalan S, Werck D, De Lorenzo G, Ferrari S, Ausubel FM, Dewdney J Activation of defense response pathways by OGs and Flg22 elicitors in Arabidopsis seedlings. Mol Plant. 2008;1(3):423-45 - PMID: 19825551 - PMCID: PMC2954645 - DOI: 10.1093/mp/ssn019

  • Liberati NT, Urbach JM, Thurber TK, Wu G, Ausubel FM Comparing insertion libraries in two Pseudomonas aeruginosa strains to assess gene essentiality. Methods Mol Biol. 2008;416:153-69 - PMID: 18392966 - DOI: 10.1007/978-1-59745-321-9_10

  • Powell JR, Ausubel FM Models of Caenorhabditis elegans infection by bacterial and fungal pathogens. Methods Mol Biol. 2008;415:403-27 - PMID: 18370168 - DOI: 10.1007/978-1-59745-570-1_24

  • Miyata S, Begun J, Troemel ER, Ausubel FM DAF-16-dependent suppression of immunity during reproduction in Caenorhabditis elegans. Genetics. 2008;178(2):903-18 - PMID: 18245330 - PMCID: PMC2248360 - DOI: 10.1534/genetics.107.083923

  • Mylonakis E, Casadevall A, Ausubel FM Exploiting amoeboid and non-vertebrate animal model systems to study the virulence of human pathogenic fungi. PLoS Pathog. 2007;3(7):e101 - PMID: 17676994 - PMCID: PMC1933451 - DOI: 10.1371/journal.ppat.0030101

  • Kuchma SL, Brothers KM, Merritt JH, Liberati NT, Ausubel FM, O'Toole GA BifA, a cyclic-Di-GMP phosphodiesterase, inversely regulates biofilm formation and swarming motility by Pseudomonas aeruginosa PA14. J Bacteriol. 2007;189(22):8165-78 - PMID: 17586641 - PMCID: PMC2168662 - DOI: 10.1128/JB.00586-07

  • Mooij MJ, Drenkard E, Llamas MA, Vandenbroucke-Grauls CM, Savelkoul PH, Ausubel FM, Bitter W Characterization of the integrated filamentous phage Pf5 and its involvement in small-colony formation. Microbiology. 2007;153(Pt 6):1790-8 - PMID: 17526836 - PMCID: PMC3820363 - DOI: 10.1099/mic.0.2006/003533-0

  • Begun J, Gaiani JM, Rohde H, Mack D, Calderwood SB, Ausubel FM, Sifri CD Staphylococcal biofilm exopolysaccharide protects against Caenorhabditis elegans immune defenses. PLoS Pathog. 2007;3(4):e57 - PMID: 17447841 - PMCID: PMC1853117 - DOI: 10.1371/journal.ppat.0030057

  • Ferrari S, Galletti R, Denoux C, De Lorenzo G, Ausubel FM, Dewdney J Resistance to Botrytis cinerea induced in Arabidopsis by elicitors is independent of salicylic acid, ethylene, or jasmonate signaling but requires PHYTOALEXIN DEFICIENT3. Plant Physiol. 2007;144(1):367-79 - PMID: 17384165 - PMCID: PMC1913806 - DOI: 10.1104/pp.107.095596

  • Breger J, Fuchs BB, Aperis G, Moy TI, Ausubel FM, Mylonakis E Antifungal chemical compounds identified using a C. elegans pathogenicity assay. PLoS Pathog. 2007;3(2):e18 - PMID: 17274686 - PMCID: PMC1790726 - DOI: 10.1371/journal.ppat.0030018

  • Lewis K, Ausubel FM Prospects for plant-derived antibacterials. Nat Biotechnol. 2006;24(12):1504-7 - PMID: 17160050 - DOI: 10.1038/nbt1206-1504

  • Lee DG, Urbach JM, Wu G, Liberati NT, Feinbaum RL, Miyata S, Diggins LT, He J, Saucier M, Déziel E, Friedman L, Li L, Grills G, Montgomery K, Kucherlapati R, Rahme LG, Ausubel FM Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial. Genome Biol. 2006;7(10):R90 - PMID: 17038190 - PMCID: PMC1794565 - DOI: 10.1186/gb-2006-7-10-r90

  • Ball AR, Casadei G, Samosorn S, Bremner JB, Ausubel FM, Moy TI, Lewis K Conjugating berberine to a multidrug efflux pump inhibitor creates an effective antimicrobial. ACS Chem Biol. 2006;1(9):594-600 - PMID: 17168555 - DOI: 10.1021/cb600238x

  • Troemel ER, Chu SW, Reinke V, Lee SS, Ausubel FM, Kim DH p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans. PLoS Genet. 2006;2(11):e183 - PMID: 17096597 - PMCID: PMC1635533 - DOI: 10.1371/journal.pgen.0020183

  • Bindschedler LV, Dewdney J, Blee KA, Stone JM, Asai T, Plotnikov J, Denoux C, Hayes T, Gerrish C, Davies DR, Ausubel FM, Bolwell GP Peroxidase-dependent apoplastic oxidative burst in Arabidopsis required for pathogen resistance. Plant J. 2006;47(6):851-63 - PMID: 16889645 - PMCID: PMC3233234 - DOI: 10.1111/j.1365-313X.2006.02837.x

  • Moy TI, Ball AR, Anklesaria Z, Casadei G, Lewis K, Ausubel FM Identification of novel antimicrobials using a live-animal infection model. Proc Natl Acad Sci U S A. 2006;103(27):10414-9 - PMID: 16801562 - PMCID: PMC1482800 - DOI: 10.1073/pnas.0604055103

  • Bush J, Jander G, Ausubel FM Prevention and control of pests and diseases. Methods Mol Biol. 2006;323:13-25 - PMID: 16739564 - DOI: 10.1385/1-59745-003-0:13

  • Kulasakara H, Lee V, Brencic A, Liberati N, Urbach J, Miyata S, Lee DG, Neely AN, Hyodo M, Hayakawa Y, Ausubel FM, Lory S Analysis of Pseudomonas aeruginosa diguanylate cyclases and phosphodiesterases reveals a role for bis-(3'-5')-cyclic-GMP in virulence. Proc Natl Acad Sci U S A. 2006;103(8):2839-44 - PMID: 16477007 - PMCID: PMC1413825 - DOI: 10.1073/pnas.0511090103

  • Liberati NT, Urbach JM, Miyata S, Lee DG, Drenkard E, Wu G, Villanueva J, Wei T, Ausubel FM An ordered, nonredundant library of Pseudomonas aeruginosa strain PA14 transposon insertion mutants. Proc Natl Acad Sci U S A. 2006;103(8):2833-8 - PMID: 16477005 - PMCID: PMC1413827 - DOI: 10.1073/pnas.0511100103

  • Ausubel FM Are innate immune signaling pathways in plants and animals conserved?. Nat Immunol. 2005;6(10):973-9 - PMID: 16177805 - DOI: 10.1038/ni1253

  • Mylonakis E, Moreno R, El Khoury JB, Idnurm A, Heitman J, Calderwood SB, Ausubel FM, Diener A Galleria mellonella as a model system to study Cryptococcus neoformans pathogenesis. Infect Immun. 2005;73(7):3842-50 - PMID: 15972469 - PMCID: PMC1168598 - DOI: 10.1128/IAI.73.7.3842-3850.2005

  • Diener AC, Ausubel FM RESISTANCE TO FUSARIUM OXYSPORUM 1, a dominant Arabidopsis disease-resistance gene, is not race specific. Genetics. 2005;171(1):305-21 - PMID: 15965251 - PMCID: PMC1456520 - DOI: 10.1534/genetics.105.042218

  • Bais HP, Prithiviraj B, Jha AK, Ausubel FM, Vivanco JM Mediation of pathogen resistance by exudation of antimicrobials from roots. Nature. 2005;434(7030):217-21 - PMID: 15759001 - DOI: 10.1038/nature03356

  • Sifri CD, Begun J, Ausubel FM The worm has turned--microbial virulence modeled in Caenorhabditis elegans. Trends Microbiol. 2005;13(3):119-27 - PMID: 15737730 - DOI: 10.1016/j.tim.2005.01.003

  • Chang JH, Urbach JM, Law TF, Arnold LW, Hu A, Gombar S, Grant SR, Ausubel FM, Dangl JL A high-throughput, near-saturating screen for type III effector genes from Pseudomonas syringae. Proc Natl Acad Sci U S A. 2005;102(7):2549-54 - PMID: 15701698 - PMCID: PMC549004 - DOI: 10.1073/pnas.0409660102

  • Begun J, Sifri CD, Goldman S, Calderwood SB, Ausubel FM Staphylococcus aureus virulence factors identified by using a high-throughput Caenorhabditis elegans-killing model. Infect Immun. 2005;73(2):872-7 - PMID: 15664928 - PMCID: PMC547013 - DOI: 10.1128/IAI.73.2.872-877.2005

  • Kim DH, Ausubel FM Evolutionary perspectives on innate immunity from the study of Caenorhabditis elegans. Curr Opin Immunol. 2005;17(1):4-10 - PMID: 15653303 - DOI: 10.1016/j.coi.2004.11.007

  • Cui J, Bahrami AK, Pringle EG, Hernandez-Guzman G, Bender CL, Pierce NE, Ausubel FM Pseudomonas syringae manipulates systemic plant defenses against pathogens and herbivores. Proc Natl Acad Sci U S A. 2005;102(5):1791-6 - PMID: 15657122 - PMCID: PMC547856 - DOI: 10.1073/pnas.0409450102

  • Garsin DA, Urbach J, Huguet-Tapia JC, Peters JE, Ausubel FM Construction of an Enterococcus faecalis Tn917-mediated-gene-disruption library offers insight into Tn917 insertion patterns. J Bacteriol. 2004;186(21):7280-9 - PMID: 15489440 - PMCID: PMC523214 - DOI: 10.1128/JB.186.21.7280-7289.2004

  • Rojo E, Martín R, Carter C, Zouhar J, Pan S, Plotnikova J, Jin H, Paneque M, Sánchez-Serrano JJ, Baker B, Ausubel FM, Raikhel NV VPEgamma exhibits a caspase-like activity that contributes to defense against pathogens. Curr Biol. 2004;14(21):1897-906 - PMID: 15530390 - DOI: 10.1016/j.cub.2004.09.056

  • Mylonakis E, Idnurm A, Moreno R, El Khoury J, Rottman JB, Ausubel FM, Heitman J, Calderwood SB Cryptococcus neoformans Kin1 protein kinase homologue, identified through a Caenorhabditis elegans screen, promotes virulence in mammals. Mol Microbiol. 2004;54(2):407-19 - PMID: 15469513 - DOI: 10.1111/j.1365-2958.2004.04310.x

  • Moy TI, Mylonakis E, Calderwood SB, Ausubel FM Cytotoxicity of hydrogen peroxide produced by Enterococcus faecium. Infect Immun. 2004;72(8):4512-20 - PMID: 15271910 - PMCID: PMC470665 - DOI: 10.1128/IAI.72.8.4512-4520.2004

  • Kim DH, Liberati NT, Mizuno T, Inoue H, Hisamoto N, Matsumoto K, Ausubel FM Integration of Caenorhabditis elegans MAPK pathways mediating immunity and stress resistance by MEK-1 MAPK kinase and VHP-1 MAPK phosphatase. Proc Natl Acad Sci U S A. 2004;101(30):10990-4 - PMID: 15256594 - PMCID: PMC503731 - DOI: 10.1073/pnas.0403546101

  • Tenor JL, McCormick BA, Ausubel FM, Aballay A Caenorhabditis elegans-based screen identifies Salmonella virulence factors required for conserved host-pathogen interactions. Curr Biol. 2004;14(11):1018-24 - PMID: 15182677 - DOI: 10.1016/j.cub.2004.05.050

  • Engelbert M, Mylonakis E, Ausubel FM, Calderwood SB, Gilmore MS Contribution of gelatinase, serine protease, and fsr to the pathogenesis of Enterococcus faecalis endophthalmitis. Infect Immun. 2004;72(6):3628-33 - PMID: 15155673 - PMCID: PMC415677 - DOI: 10.1128/IAI.72.6.3628-3633.2004

  • Mizuno T, Hisamoto N, Terada T, Kondo T, Adachi M, Nishida E, Kim DH, Ausubel FM, Matsumoto K The Caenorhabditis elegans MAPK phosphatase VHP-1 mediates a novel JNK-like signaling pathway in stress response. EMBO J. 2004;23(11):2226-34 - PMID: 15116070 - PMCID: PMC419906 - DOI: 10.1038/sj.emboj.7600226

  • Liberati NT, Fitzgerald KA, Kim DH, Feinbaum R, Golenbock DT, Ausubel FM Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response. Proc Natl Acad Sci U S A. 2004;101(17):6593-8 - PMID: 15123841 - PMCID: PMC404090 - DOI: 10.1073/pnas.0308625101

  • Apidianakis Y, Rahme LG, Heitman J, Ausubel FM, Calderwood SB, Mylonakis E Challenge of Drosophila melanogaster with Cryptococcus neoformans and role of the innate immune response. Eukaryot Cell. 2004;3(2):413-9 - PMID: 15075271 - PMCID: PMC387633 - DOI: 10.1128/ec.3.2.413-419.2004

  • Ferrari S, Plotnikova JM, De Lorenzo G, Ausubel FM Arabidopsis local resistance to Botrytis cinerea involves salicylic acid and camalexin and requires EDS4 and PAD2, but not SID2, EDS5 or PAD4. Plant J. 2003;35(2):193-205 - PMID: 12848825 - DOI: 10.1046/j.1365-313x.2003.01794.x

  • Garsin DA, Villanueva JM, Begun J, Kim DH, Sifri CD, Calderwood SB, Ruvkun G, Ausubel FM Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens. Science. 2003;300(5627):1921 - PMID: 12817143 - DOI: 10.1126/science.1080147

  • Garsin DA, Villanueva JM, Begun J, Kim DH, Sifri CD, Calderwood SB, Ruvkun G, Ausubel FM Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens. Science. 2003;300(5627):1921 - PMID: 12817143 - DOI: 10.1126/science.1080147

  • Mylonakis E, Ausubel FM, Tang RJ, Calderwood SB The art of serendipity: killing of Caenorhabditis elegans by human pathogens as a model of bacterial and fungal pathogenesis. Expert Rev Anti Infect Ther. 2003;1(1):167-73 - PMID: 15482109 - DOI: 10.1586/14787210.1.1.167

  • Miyata S, Casey M, Frank DW, Ausubel FM, Drenkard E Use of the Galleria mellonella caterpillar as a model host to study the role of the type III secretion system in Pseudomonas aeruginosa pathogenesis. Infect Immun. 2003;71(5):2404-13 - PMID: 12704110 - PMCID: PMC153283 - DOI: 10.1128/iai.71.5.2404-2413.2003

  • Sifri CD, Begun J, Ausubel FM, Calderwood SB Caenorhabditis elegans as a model host for Staphylococcus aureus pathogenesis. Infect Immun. 2003;71(4):2208-17 - PMID: 12654843 - PMCID: PMC152095 - DOI: 10.1128/iai.71.4.2208-2217.2003

  • Alonso JM, Stepanova AN, Solano R, Wisman E, Ferrari S, Ausubel FM, Ecker JR Five components of the ethylene-response pathway identified in a screen for weak ethylene-insensitive mutants in Arabidopsis. Proc Natl Acad Sci U S A. 2003;100(5):2992-7 - PMID: 12606727 - PMCID: PMC151454 - DOI: 10.1073/pnas.0438070100

  • Coleman FT, Mueschenborn S, Meluleni G, Ray C, Carey VJ, Vargas SO, Cannon CL, Ausubel FM, Pier GB Hypersusceptibility of cystic fibrosis mice to chronic Pseudomonas aeruginosa oropharyngeal colonization and lung infection. Proc Natl Acad Sci U S A. 2003;100(4):1949-54 - PMID: 12578988 - PMCID: PMC149939 - DOI: 10.1073/pnas.0437901100

  • Aballay A, Drenkard E, Hilbun LR, Ausubel FM Caenorhabditis elegans innate immune response triggered by Salmonella enterica requires intact LPS and is mediated by a MAPK signaling pathway. Curr Biol. 2003;13(1):47-52 - PMID: 12526744 - DOI: 10.1016/s0960-9822(02)01396-9

  • Ferrari S, Vairo D, Ausubel FM, Cervone F, De Lorenzo G Tandemly duplicated Arabidopsis genes that encode polygalacturonase-inhibiting proteins are regulated coordinately by different signal transduction pathways in response to fungal infection. Plant Cell. 2003;15(1):93-106 - PMID: 12509524 - PMCID: PMC143454 - DOI: 10.1105/tpc.005165

  • Mylonakis E, Ausubel FM, Perfect JR, Heitman J, Calderwood SB Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis. Proc Natl Acad Sci U S A. 2002;99(24):15675-80 - PMID: 12438649 - PMCID: PMC137775 - DOI: 10.1073/pnas.232568599

  • Sifri CD, Mylonakis E, Singh KV, Qin X, Garsin DA, Murray BE, Ausubel FM, Calderwood SB Virulence effect of Enterococcus faecalis protease genes and the quorum-sensing locus fsr in Caenorhabditis elegans and mice. Infect Immun. 2002;70(10):5647-50 - PMID: 12228293 - PMCID: PMC128331 - DOI: 10.1128/iai.70.10.5647-5650.2002

  • Mylonakis E, Engelbert M, Qin X, Sifri CD, Murray BE, Ausubel FM, Gilmore MS, Calderwood SB The Enterococcus faecalis fsrB gene, a key component of the fsr quorum-sensing system, is associated with virulence in the rabbit endophthalmitis model. Infect Immun. 2002;70(8):4678-81 - PMID: 12117982 - PMCID: PMC128160 - DOI: 10.1128/iai.70.8.4678-4681.2002

  • Kim DH, Feinbaum R, Alloing G, Emerson FE, Garsin DA, Inoue H, Tanaka-Hino M, Hisamoto N, Matsumoto K, Tan MW, Ausubel FM A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity. Science. 2002;297(5581):623-6 - PMID: 12142542 - DOI: 10.1126/science.1073759

  • Cui J, Jander G, Racki LR, Kim PD, Pierce NE, Ausubel FM Signals involved in Arabidopsis resistance to Trichoplusia ni caterpillars induced by virulent and avirulent strains of the phytopathogen Pseudomonas syringae. Plant Physiol. 2002;129(2):551-64 - PMID: 12068100 - PMCID: PMC161673 - DOI: 10.1104/pp.010815

  • Drenkard E, Ausubel FM Pseudomonas biofilm formation and antibiotic resistance are linked to phenotypic variation. Nature. 2002;416(6882):740-3 - PMID: 11961556 - DOI: 10.1038/416740a

  • Kudva IT, Evans PS, Perna NT, Barrett TJ, DeCastro GJ, Ausubel FM, Blattner FR, Calderwood SB Polymorphic amplified typing sequences provide a novel approach to Escherichia coli O157:H7 strain typing. J Clin Microbiol. 2002;40(4):1152-9 - PMID: 11923324 - PMCID: PMC140341 - DOI: 10.1128/jcm.40.4.1152-1159.2002

  • Kudva IT, Evans PS, Perna NT, Barrett TJ, Ausubel FM, Blattner FR, Calderwood SB Strains of Escherichia coli O157:H7 differ primarily by insertions or deletions, not single-nucleotide polymorphisms. J Bacteriol. 2002;184(7):1873-9 - PMID: 11889093 - PMCID: PMC134921 - DOI: 10.1128/jb.184.7.1873-1879.2002

  • Asai T, Tena G, Plotnikova J, Willmann MR, Chiu WL, Gomez-Gomez L, Boller T, Ausubel FM, Sheen J MAP kinase signalling cascade in Arabidopsis innate immunity. Nature. 2002;415(6875):977-83 - PMID: 11875555 - DOI: 10.1038/415977a

  • Aballay A, Ausubel FM Caenorhabditis elegans as a host for the study of host-pathogen interactions. Curr Opin Microbiol. 2002;5(1):97-101 - PMID: 11834377 - DOI: 10.1016/s1369-5274(02)00293-x

  • Choi JY, Sifri CD, Goumnerov BC, Rahme LG, Ausubel FM, Calderwood SB Identification of virulence genes in a pathogenic strain of Pseudomonas aeruginosa by representational difference analysis. J Bacteriol. 2002;184(4):952-61 - PMID: 11807055 - PMCID: PMC134824 - DOI: 10.1128/jb.184.4.952-961.2002

  • Hendrickson EL, Plotnikova J, Mahajan-Miklos S, Rahme LG, Ausubel FM Differential roles of the Pseudomonas aeruginosa PA14 rpoN gene in pathogenicity in plants, nematodes, insects, and mice. J Bacteriol. 2001;183(24):7126-34 - PMID: 11717271 - PMCID: PMC95561 - DOI: 10.1128/JB.183.24.7126-7134.2001

  • Wildermuth MC, Dewdney J, Wu G, Ausubel FM Isochorismate synthase is required to synthesize salicylic acid for plant defence. Nature. 2001;414(6863):562-5 - PMID: 11734859 - DOI: 10.1038/35107108

  • Garsin DA, Sifri CD, Mylonakis E, Qin X, Singh KV, Murray BE, Calderwood SB, Ausubel FM A simple model host for identifying Gram-positive virulence factors. Proc Natl Acad Sci U S A. 2001;98(19):10892-7 - PMID: 11535834 - PMCID: PMC58570 - DOI: 10.1073/pnas.191378698

  • Yorgey P, Rahme LG, Tan MW, Ausubel FM The roles of mucD and alginate in the virulence of Pseudomonas aeruginosa in plants, nematodes and mice. Mol Microbiol. 2001;41(5):1063-76 - PMID: 11555287 - DOI: 10.1046/j.1365-2958.2001.02580.x

  • Jander G, Cui J, Nhan B, Pierce NE, Ausubel FM The TASTY locus on chromosome 1 of Arabidopsis affects feeding of the insect herbivore Trichoplusia ni. Plant Physiol. 2001;126(2):890-8 - PMID: 11402216 - PMCID: PMC111178 - DOI: 10.1104/pp.126.2.890

  • Aballay A, Ausubel FM Programmed cell death mediated by ced-3 and ced-4 protects Caenorhabditis elegans from Salmonella typhimurium-mediated killing. Proc Natl Acad Sci U S A. 2001;98(5):2735-9 - PMID: 11226309 - PMCID: PMC30208 - DOI: 10.1073/pnas.041613098

  • Ausubel FM Arabidopsis genome. A milestone in plant biology. Plant Physiol. 2000;124(4):1451-4 - PMID: 11115856 - PMCID: PMC1539293 - DOI: 10.1104/pp.124.4.1451

  • Plotnikova JM, Rahme LG, Ausubel FM Pathogenesis of the human opportunistic pathogen Pseudomonas aeruginosa PA14 in Arabidopsis. Plant Physiol. 2000;124(4):1766-74 - PMID: 11115892 - PMCID: PMC59873 - DOI: 10.1104/pp.124.4.1766

  • Drenkard E, Richter BG, Rozen S, Stutius LM, Angell NA, Mindrinos M, Cho RJ, Oefner PJ, Davis RW, Ausubel FM A simple procedure for the analysis of single nucleotide polymorphisms facilitates map-based cloning in Arabidopsis. Plant Physiol. 2000;124(4):1483-92 - PMID: 11115864 - PMCID: PMC1539302 - DOI: 10.1104/pp.124.4.1483

  • Tao Y, Yuan F, Leister RT, Ausubel FM, Katagiri F Mutational analysis of the Arabidopsis nucleotide binding site-leucine-rich repeat resistance gene RPS2. Plant Cell. 2000;12(12):2541-2554 - PMID: 11148296 - PMCID: PMC102236 - DOI: 10.1105/tpc.12.12.2541

  • Aballay A, Yorgey P, Ausubel FM Salmonella typhimurium proliferates and establishes a persistent infection in the intestine of Caenorhabditis elegans. Curr Biol. 2000;10(23):1539-42 - PMID: 11114525 - DOI: 10.1016/s0960-9822(00)00830-7

  • Clarke JD, Volko SM, Ledford H, Ausubel FM, Dong X Roles of salicylic acid, jasmonic acid, and ethylene in cpr-induced resistance in arabidopsis. Plant Cell. 2000;12(11):2175-90 - PMID: 11090217 - PMCID: PMC150166 - DOI: 10.1105/tpc.12.11.2175

  • Asai T, Stone JM, Heard JE, Kovtun Y, Yorgey P, Sheen J, Ausubel FM Fumonisin B1-induced cell death in arabidopsis protoplasts requires jasmonate-, ethylene-, and salicylate-dependent signaling pathways. Plant Cell. 2000;12(10):1823-36 - PMID: 11041879 - PMCID: PMC149122 - DOI: 10.1105/tpc.12.10.1823

  • Stone JM, Heard JE, Asai T, Ausubel FM Simulation of fungal-mediated cell death by fumonisin B1 and selection of fumonisin B1-resistant (fbr) Arabidopsis mutants. Plant Cell. 2000;12(10):1811-22 - PMID: 11041878 - PMCID: PMC149121 - DOI: 10.1105/tpc.12.10.1811

  • Dewdney J, Reuber TL, Wildermuth MC, Devoto A, Cui J, Stutius LM, Drummond EP, Ausubel FM Three unique mutants of Arabidopsis identify eds loci required for limiting growth of a biotrophic fungal pathogen. Plant J. 2000;24(2):205-18 - PMID: 11069695 - DOI: 10.1046/j.1365-313x.2000.00870.x

  • Ilag LL, Yadav RC, Huang N, Ronald PC, Ausubel FM Isolation and characterization of disease resistance gene homologues from rice cultivar IR64. Gene. 2000;255(2):245-55 - PMID: 11024284 - DOI: 10.1016/s0378-1119(00)00333-4

  • Mahajan-Miklos S, Rahme LG, Ausubel FM Elucidating the molecular mechanisms of bacterial virulence using non-mammalian hosts. Mol Microbiol. 2000;37(5):981-8 - PMID: 10972817 - DOI: 10.1046/j.1365-2958.2000.02056.x

  • Rahme LG, Ausubel FM, Cao H, Drenkard E, Goumnerov BC, Lau GW, Mahajan-Miklos S, Plotnikova J, Tan MW, Tsongalis J, Walendziewicz CL, Tompkins RG Plants and animals share functionally common bacterial virulence factors. Proc Natl Acad Sci U S A. 2000;97(16):8815-21 - PMID: 10922040 - PMCID: PMC34017 - DOI: 10.1073/pnas.97.16.8815

  • Jander G, Rahme LG, Ausubel FM Positive correlation between virulence of Pseudomonas aeruginosa mutants in mice and insects. J Bacteriol. 2000;182(13):3843-5 - PMID: 10851003 - PMCID: PMC94559 - DOI: 10.1128/jb.182.13.3843-3845.2000

  • Hendrickson EL, Guevera P, Peñaloza-Vàzquez A, Shao J, Bender C, Ausubel FM Virulence of the phytopathogen Pseudomonas syringae pv. maculicola is rpoN dependent. J Bacteriol. 2000;182(12):3498-507 - PMID: 10852883 - PMCID: PMC101941 - DOI: 10.1128/jb.182.12.3498-3507.2000

  • Hendrickson EL, Guevera P, Ausubel FM The alternative sigma factor RpoN is required for hrp activity in Pseudomonas syringae pv. maculicola and acts at the level of hrpL transcription. J Bacteriol. 2000;182(12):3508-16 - PMID: 10852884 - PMCID: PMC101944 - DOI: 10.1128/jb.182.12.3508-3516.2000

  • Tan MW, Ausubel FM Caenorhabditis elegans: a model genetic host to study Pseudomonas aeruginosa pathogenesis. Curr Opin Microbiol. 2000;3(1):29-34 - PMID: 10679415 - DOI: 10.1016/s1369-5274(99)00047-8

  • Jirage D, Tootle TL, Reuber TL, Frost LN, Feys BJ, Parker JE, Ausubel FM, Glazebrook J Arabidopsis thaliana PAD4 encodes a lipase-like gene that is important for salicylic acid signaling. Proc Natl Acad Sci U S A. 1999;96(23):13583-8 - PMID: 10557364 - PMCID: PMC23991 - DOI: 10.1073/pnas.96.23.13583

  • Cho RJ, Mindrinos M, Richards DR, Sapolsky RJ, Anderson M, Drenkard E, Dewdney J, Reuber TL, Stammers M, Federspiel N, Theologis A, Yang WH, Hubbell E, Au M, Chung EY, Lashkari D, Lemieux B, Dean C, Lipshutz RJ, Ausubel FM, Davis RW, Oefner PJ Genome-wide mapping with biallelic markers in Arabidopsis thaliana. Nat Genet. 1999;23(2):203-7 - PMID: 10508518 - DOI: 10.1038/13833

  • Tan MW, Rahme LG, Sternberg JA, Tompkins RG, Ausubel FM Pseudomonas aeruginosa killing of Caenorhabditis elegans used to identify P. aeruginosa virulence factors. Proc Natl Acad Sci U S A. 1999;96(5):2408-13 - PMID: 10051655 - PMCID: PMC26797 - DOI: 10.1073/pnas.96.5.2408

  • Tan MW, Mahajan-Miklos S, Ausubel FM Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis. Proc Natl Acad Sci U S A. 1999;96(2):715-20 - PMID: 9892699 - PMCID: PMC15202 - DOI: 10.1073/pnas.96.2.715

  • Mahajan-Miklos S, Tan MW, Rahme LG, Ausubel FM Molecular mechanisms of bacterial virulence elucidated using a Pseudomonas aeruginosa-Caenorhabditis elegans pathogenesis model. Cell. 1999;96(1):47-56 - PMID: 9989496 - DOI: 10.1016/s0092-8674(00)80958-7

  • Wong SM, Carroll PA, Rahme LG, Ausubel FM, Calderwood SB Modulation of expression of the ToxR regulon in Vibrio cholerae by a member of the two-component family of response regulators. Infect Immun. 1998;66(12):5854-61 - PMID: 9826365 - PMCID: PMC108741 - DOI: 10.1128/IAI.66.12.5854-5861.1998

  • Reuber TL, Plotnikova JM, Dewdney J, Rogers EE, Wood W, Ausubel FM Correlation of defense gene induction defects with powdery mildew susceptibility in Arabidopsis enhanced disease susceptibility mutants. Plant J. 1998;16(4):473-85 - PMID: 9881167 - DOI: 10.1046/j.1365-313x.1998.00319.x

  • Glazebrook J, Drenkard E, Preuss D, Ausubel FM Use of cleaved amplified polymorphic sequences (CAPS) as genetic markers in Arabidopsis thaliana. Methods Mol Biol. 1998;82:173-82 - PMID: 9664424 - DOI: 10.1385/0-89603-391-0:173

  • Volko SM, Boller T, Ausubel FM Isolation of new Arabidopsis mutants with enhanced disease susceptibility to Pseudomonas syringae by direct screening. Genetics. 1998;149(2):537-48 - PMID: 9611172 - PMCID: PMC1460196 - DOI: 10.1093/genetics/149.2.537

  • Kubasek WL, Ausubel FM, Shirley BW A light-independent developmental mechanism potentiates flavonoid gene expression in Arabidopsis seedlings. Plant Mol Biol. 1998;37(2):217-23 - PMID: 9617795 - DOI: 10.1023/a:1005977103116

  • Glazebrook J, Rogers EE, Ausubel FM Use of Arabidopsis for genetic dissection of plant defense responses. Annu Rev Genet. 1998;31:547-69 - PMID: 9442907 - DOI: 10.1146/annurev.genet.31.1.547

  • Pegues DA, Colby C, Hibberd PL, Cohen LG, Ausubel FM, Calderwood SB, Hooper DC The epidemiology of resistance to ofloxacin and oxacillin among clinical coagulase-negative staphylococcal isolates: analysis of risk factors and strain types. Clin Infect Dis. 1998;26(1):72-9 - PMID: 9455512 - DOI: 10.1086/516270

  • Rahme LG, Tan MW, Le L, Wong SM, Tompkins RG, Calderwood SB, Ausubel FM Use of model plant hosts to identify Pseudomonas aeruginosa virulence factors. Proc Natl Acad Sci U S A. 1997;94(24):13245-50 - PMID: 9371831 - PMCID: PMC24294 - DOI: 10.1073/pnas.94.24.13245

  • Li J, Kasper DL, Ausubel FM, Rosner B, Michel JL Inactivation of the alpha C protein antigen gene, bca, by a novel shuttle/suicide vector results in attenuation of virulence and immunity in group B Streptococcus. Proc Natl Acad Sci U S A. 1997;94(24):13251-6 - PMID: 9371832 - PMCID: PMC24295 - DOI: 10.1073/pnas.94.24.13251

  • Glazebrook J, Zook M, Mert F, Kagan I, Rogers EE, Crute IR, Holub EB, Hammerschmidt R, Ausubel FM Phytoalexin-deficient mutants of Arabidopsis reveal that PAD4 encodes a regulatory factor and that four PAD genes contribute to downy mildew resistance. Genetics. 1997;146(1):381-92 - PMID: 9136026 - PMCID: PMC1207952 - DOI: 10.1093/genetics/146.1.381

  • Rogers EE, Ausubel FM Arabidopsis enhanced disease susceptibility mutants exhibit enhanced susceptibility to several bacterial pathogens and alterations in PR-1 gene expression. Plant Cell. 1997;9(3):305-16 - PMID: 9090877 - PMCID: PMC156920 - DOI: 10.1105/tpc.9.3.305

  • Leister RT, Ausubel FM, Katagiri F Molecular recognition of pathogen attack occurs inside of plant cells in plant disease resistance specified by the Arabidopsis genes RPS2 and RPM1. Proc Natl Acad Sci U S A. 1996;93(26):15497-502 - PMID: 8986840 - PMCID: PMC26433 - DOI: 10.1073/pnas.93.26.15497

  • Calderwood SB, Baker MA, Carroll PA, Michel JL, Arbeit RD, Ausubel FM Use of cleaved amplified polymorphic sequences to distinguish strains of Staphylococcus epidermidis. J Clin Microbiol. 1996;34(11):2860-5 - PMID: 8897202 - PMCID: PMC229423 - DOI: 10.1128/JCM.34.11.2860-2865.1996

  • Rogers EE, Glazebrook J, Ausubel FM Mode of action of the Arabidopsis thaliana phytoalexin camalexin and its role in Arabidopsis-pathogen interactions. Mol Plant Microbe Interact. 1996;9(8):748-57 - PMID: 8870273 - DOI: 10.1094/mpmi-9-0748

  • Glazebrook J, Rogers EE, Ausubel FM Isolation of Arabidopsis mutants with enhanced disease susceptibility by direct screening. Genetics. 1996;143(2):973-82 - PMID: 8725243 - PMCID: PMC1207353 - DOI: 10.1093/genetics/143.2.973

  • Reuber TL, Ausubel FM Isolation of Arabidopsis genes that differentiate between resistance responses mediated by the RPS2 and RPM1 disease resistance genes. Plant Cell. 1996;8(2):241-9 - PMID: 8742710 - PMCID: PMC161094 - DOI: 10.1105/tpc.8.2.241

  • Reuber TL, Ausubel FM Differential mRNA display. Methods Cell Biol. 1996;49:431-40 - PMID: 8531774

  • Shirley BW, Kubasek WL, Storz G, Bruggemann E, Koornneef M, Ausubel FM, Goodman HM Analysis of Arabidopsis mutants deficient in flavonoid biosynthesis. Plant J. 1995;8(5):659-71 - PMID: 8528278 - DOI: 10.1046/j.1365-313x.1995.08050659.x

  • Rahme LG, Stevens EJ, Wolfort SF, Shao J, Tompkins RG, Ausubel FM Common virulence factors for bacterial pathogenicity in plants and animals. Science. 1995;268(5219):1899-902 - PMID: 7604262 - DOI: 10.1126/science.7604262

  • Ausubel FM, Katagiri F, Mindrinos M, Glazebrook J Use of Arabidopsis thaliana defense-related mutants to dissect the plant response to pathogens. Proc Natl Acad Sci U S A. 1995;92(10):4189-96 - PMID: 7753782 - PMCID: PMC41909 - DOI: 10.1073/pnas.92.10.4189

  • Staskawicz BJ, Ausubel FM, Baker BJ, Ellis JG, Jones JD Molecular genetics of plant disease resistance. Science. 1995;268(5211):661-7 - PMID: 7732374 - DOI: 10.1126/science.7732374

  • Hanfstingl U, Berry A, Kellogg EA, Costa JT, Rüdiger W, Ausubel FM Haplotypic divergence coupled with lack of diversity at the Arabidopsis thaliana alcohol dehydrogenase locus: roles for both balancing and directional selection?. Genetics. 1994;138(3):811-28 - PMID: 7851777 - PMCID: PMC1206230 - DOI: 10.1093/genetics/138.3.811

  • Mindrinos M, Katagiri F, Yu GL, Ausubel FM The A. thaliana disease resistance gene RPS2 encodes a protein containing a nucleotide-binding site and leucine-rich repeats. Cell. 1994;78(6):1089-99 - PMID: 7923358 - DOI: 10.1016/0092-8674(94)90282-8

  • Glazebrook J, Ausubel FM Isolation of phytoalexin-deficient mutants of Arabidopsis thaliana and characterization of their interactions with bacterial pathogens. Proc Natl Acad Sci U S A. 1994;91(19):8955-9 - PMID: 8090752 - PMCID: PMC44725 - DOI: 10.1073/pnas.91.19.8955

  • Greenberg JT, Guo A, Klessig DF, Ausubel FM Programmed cell death in plants: a pathogen-triggered response activated coordinately with multiple defense functions. Cell. 1994;77(4):551-63 - PMID: 8187175 - DOI: 10.1016/0092-8674(94)90217-8

  • Yu GL, Katagiri F, Ausubel FM Arabidopsis mutations at the RPS2 locus result in loss of resistance to Pseudomonas syringae strains expressing the avirulence gene avrRpt2. Mol Plant Microbe Interact. 1993;6(4):434-43 - PMID: 8400373 - DOI: 10.1094/mpmi-6-434

  • Susek RE, Ausubel FM, Chory J Signal transduction mutants of Arabidopsis uncouple nuclear CAB and RBCS gene expression from chloroplast development. Cell. 1993;74(5):787-99 - PMID: 7690685 - DOI: 10.1016/0092-8674(93)90459-4

  • Konieczny A, Ausubel FM A procedure for mapping Arabidopsis mutations using co-dominant ecotype-specific PCR-based markers. Plant J. 1993;4(2):403-10 - PMID: 8106085 - DOI: 10.1046/j.1365-313x.1993.04020403.x

  • Greenberg JT, Ausubel FM Arabidopsis mutants compromised for the control of cellular damage during pathogenesis and aging. Plant J. 1993;4(2):327-41 - PMID: 8220484 - DOI: 10.1046/j.1365-313x.1993.04020327.x

  • Melan MA, Dong X, Endara ME, Davis KR, Ausubel FM, Peterman TK An Arabidopsis thaliana lipoxygenase gene can be induced by pathogens, abscisic acid, and methyl jasmonate. Plant Physiol. 1993;101(2):441-50 - PMID: 7506426 - PMCID: PMC160590 - DOI: 10.1104/pp.101.2.441

  • Michel JL, Madoff LC, Olson K, Kling DE, Kasper DL, Ausubel FM Large, identical, tandem repeating units in the C protein alpha antigen gene, bca, of group B streptococci. Proc Natl Acad Sci U S A. 1992;89(21):10060-4 - PMID: 1438195 - PMCID: PMC50277 - DOI: 10.1073/pnas.89.21.10060

  • Kubasek WL, Shirley BW, McKillop A, Goodman HM, Briggs W, Ausubel FM Regulation of Flavonoid Biosynthetic Genes in Germinating Arabidopsis Seedlings. Plant Cell. 1992;4(10):1229-1236 - PMID: 12297632 - PMCID: PMC160210 - DOI: 10.1105/tpc.4.10.1229

  • Voytas DF, Cummings MP, Koniczny A, Ausubel FM, Rodermel SR copia-like retrotransposons are ubiquitous among plants. Proc Natl Acad Sci U S A. 1992;89(15):7124-8 - PMID: 1379734 - PMCID: PMC49658 - DOI: 10.1073/pnas.89.15.7124

  • Sun T, Goodman HM, Ausubel FM Cloning the Arabidopsis GA1 Locus by Genomic Subtraction. Plant Cell. 1992;4(2):119-128 - PMID: 12297643 - PMCID: PMC160113 - DOI: 10.1105/tpc.4.2.119

  • Huala E, Stigter J, Ausubel FM The central domain of Rhizobium leguminosarum DctD functions independently to activate transcription. J Bacteriol. 1992;174(4):1428-31 - PMID: 1735730 - PMCID: PMC206444 - DOI: 10.1128/jb.174.4.1428-1431.1992

  • Dickstein R, Scheirer DC, Fowle WH, Ausubel FM Nodules elicited by Rhizobium meliloti heme mutants are arrested at an early stage of development. Mol Gen Genet. 1991;230(3):423-32 - PMID: 1766439 - DOI: 10.1007/BF00280299

  • Keith B, Dong XN, Ausubel FM, Fink GR Differential induction of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase genes in Arabidopsis thaliana by wounding and pathogenic attack. Proc Natl Acad Sci U S A. 1991;88(19):8821-5 - PMID: 1681544 - PMCID: PMC52602 - DOI: 10.1073/pnas.88.19.8821

  • Michel JL, Madoff LC, Kling DE, Kasper DL, Ausubel FM Cloned alpha and beta C-protein antigens of group B streptococci elicit protective immunity. Infect Immun. 1991;59(6):2023-8 - PMID: 1674738 - PMCID: PMC257960 - DOI: 10.1128/IAI.59.6.2023-2028.1991

  • Richards EJ, Goodman HM, Ausubel FM The centromere region of Arabidopsis thaliana chromosome 1 contains telomere-similar sequences. Nucleic Acids Res. 1991;19(12):3351-7 - PMID: 1648204 - PMCID: PMC328334 - DOI: 10.1093/nar/19.12.3351

  • Feinbaum RL, Storz G, Ausubel FM High intensity and blue light regulated expression of chimeric chalcone synthase genes in transgenic Arabidopsis thaliana plants. Mol Gen Genet. 1991;226(3):449-56 - PMID: 2038307 - DOI: 10.1007/BF00260658

  • Konieczny A, Voytas DF, Cummings MP, Ausubel FM A superfamily of Arabidopsis thaliana retrotransposons. Genetics. 1991;127(4):801-9 - PMID: 1709409 - PMCID: PMC1204407 - DOI: 10.1093/genetics/127.4.801

  • Dong X, Mindrinos M, Davis KR, Ausubel FM Induction of Arabidopsis defense genes by virulent and avirulent Pseudomonas syringae strains and by a cloned avirulence gene. Plant Cell. 1991;3(1):61-72 - PMID: 1824335 - PMCID: PMC159979 - DOI: 10.1105/tpc.3.1.61

  • Huala E, Moon AL, Ausubel FM Aerobic inactivation of Rhizobium meliloti NifA in Escherichia coli is mediated by lon and two newly identified genes, snoB and snoC. J Bacteriol. 1991;173(1):382-90 - PMID: 1846139 - PMCID: PMC207197 - DOI: 10.1128/jb.173.1.382-390.1991

  • Voytas DF, Konieczny A, Cummings MP, Ausubel FM The structure, distribution and evolution of the Ta1 retrotransposable element family of Arabidopsis thaliana. Genetics. 1990;126(3):713-21 - PMID: 2174394 - PMCID: PMC1204225 - DOI: 10.1093/genetics/126.3.713

  • Albright LM, Huala E, Ausubel FM Prokaryotic signal transduction mediated by sensor and regulator protein pairs. Annu Rev Genet. 1990;23:311-36 - PMID: 2694934 - DOI: 10.1146/annurev.ge.23.120189.001523

  • Straus D, Ausubel FM Genomic subtraction for cloning DNA corresponding to deletion mutations. Proc Natl Acad Sci U S A. 1990;87(5):1889-93 - PMID: 2408039 - PMCID: PMC53589 - DOI: 10.1073/pnas.87.5.1889

  • Honma MA, Asomaning M, Ausubel FM Rhizobium meliloti nodD genes mediate host-specific activation of nodABC. J Bacteriol. 1990;172(2):901-11 - PMID: 2298703 - PMCID: PMC208518 - DOI: 10.1128/jb.172.2.901-911.1990

  • Chory J, Peto C, Feinbaum R, Pratt L, Ausubel F Arabidopsis thaliana mutant that develops as a light-grown plant in the absence of light. Cell. 1989;58(5):991-9 - PMID: 2776216 - DOI: 10.1016/0092-8674(89)90950-1

  • Bloch CA, Thorne GM, Ausubel FM General method for site-directed mutagenesis in Escherichia coli O18ac:K1:H7: deletion of the inducible superoxide dismutase gene, sodA, does not diminish bacteremia in neonatal rats. Infect Immun. 1989;57(7):2141-8 - PMID: 2543632 - PMCID: PMC313853 - DOI: 10.1128/IAI.57.7.2141-2148.1989

  • Huala E, Ausubel FM The central domain of Rhizobium meliloti NifA is sufficient to activate transcription from the R. meliloti nifH promoter. J Bacteriol. 1989;171(6):3354-65 - PMID: 2722751 - PMCID: PMC210058 - DOI: 10.1128/jb.171.6.3354-3365.1989

  • Albright LM, Ronson CW, Nixon BT, Ausubel FM Identification of a gene linked to Rhizobium meliloti ntrA whose product is homologous to a family to ATP-binding proteins. J Bacteriol. 1989;171(4):1932-41 - PMID: 2703463 - PMCID: PMC209842 - DOI: 10.1128/jb.171.4.1932-1941.1989

  • Olszewski NE, Gast RT, Ausubel FM A dual-labeling method for identifying differentially expressed genes: use in the identification of cDNA clones that hybridize to RNAs whose abundance in tomato flowers is potentially regulated by gibberellins. Gene. 1989;77(1):155-62 - PMID: 2663653 - DOI: 10.1016/0378-1119(89)90369-7

  • de Bruijn FJ, Rossbach S, Schneider M, Ratet P, Messmer S, Szeto WW, Ausubel FM, Schell J Rhizobium meliloti 1021 has three differentially regulated loci involved in glutamine biosynthesis, none of which is essential for symbiotic nitrogen fixation. J Bacteriol. 1989;171(3):1673-82 - PMID: 2563998 - PMCID: PMC209797 - DOI: 10.1128/jb.171.3.1673-1682.1989

  • Debellé F, Maillet F, Vasse J, Rosenberg C, de Billy F, Truchet G, Dénarié J, Ausubel FM Interference between Rhizobium meliloti and Rhizobium trifolii nodulation genes: genetic basis of R. meliloti dominance. J Bacteriol. 1988;170(12):5718-27 - PMID: 2848012 - PMCID: PMC211674 - DOI: 10.1128/jb.170.12.5718-5727.1988

  • Voytas DF, Ausubel FM A copia-like transposable element family in Arabidopsis thaliana. Nature. 1988;336(6196):242-4 - PMID: 2904123 - DOI: 10.1038/336242a0

  • Olszewski NE, Martin FB, Ausubel FM Specialized binary vector for plant transformation: expression of the Arabidopsis thaliana AHAS gene in Nicotiana tabacum. Nucleic Acids Res. 1988;16(22):10765-82 - PMID: 3060849 - PMCID: PMC338938 - DOI: 10.1093/nar/16.22.10765

  • Dickstein R, Bisseling T, Reinhold VN, Ausubel FM Expression of nodule-specific genes in alfalfa root nodules blocked at an early stage of development. Genes Dev. 1988;2(6):677-87 - PMID: 3417147 - DOI: 10.1101/gad.2.6.677

  • Feinbaum RL, Ausubel FM Transcriptional regulation of the Arabidopsis thaliana chalcone synthase gene. Mol Cell Biol. 1988;8(5):1985-92 - PMID: 3386631 - PMCID: PMC363377 - DOI: 10.1128/mcb.8.5.1985

  • Richards EJ, Ausubel FM Isolation of a higher eukaryotic telomere from Arabidopsis thaliana. Cell. 1988;53(1):127-36 - PMID: 3349525 - DOI: 10.1016/0092-8674(88)90494-1

  • Dunn K, Dickstein R, Feinbaum R, Burnett BK, Peterman TK, Thoidis G, Goodman HM, Ausubel FM Developmental regulation of nodule-specific genes in alfalfa root nodules. Mol Plant Microbe Interact. 1988;1(2):66-74 - PMID: 2908768 - DOI: 10.1094/mpmi-1-066

  • Honma MA, Ausubel FM Rhizobium meliloti has three functional copies of the nodD symbiotic regulatory gene. Proc Natl Acad Sci U S A. 1987;84(23):8558-62 - PMID: 3479806 - PMCID: PMC299584 - DOI: 10.1073/pnas.84.23.8558

  • Ronson CW, Astwood PM, Nixon BT, Ausubel FM Deduced products of C4-dicarboxylate transport regulatory genes of Rhizobium leguminosarum are homologous to nitrogen regulatory gene products. Nucleic Acids Res. 1987;15(19):7921-34 - PMID: 3671068 - PMCID: PMC306317 - DOI: 10.1093/nar/15.19.7921

  • Ronson CW, Nixon BT, Ausubel FM Conserved domains in bacterial regulatory proteins that respond to environmental stimuli. Cell. 1987;49(5):579-81 - PMID: 3555840 - DOI: 10.1016/0092-8674(87)90530-7

  • Ronson CW, Nixon BT, Albright LM, Ausubel FM Rhizobium meliloti ntrA (rpoN) gene is required for diverse metabolic functions. J Bacteriol. 1987;169(6):2424-31 - PMID: 3034856 - PMCID: PMC212082 - DOI: 10.1128/jb.169.6.2424-2431.1987

  • Wilson KJ, Anjaiah V, Nambiar PT, Ausubel FM Isolation and characterization of symbiotic mutants of bradyrhizobium sp. (Arachis) strain NC92: mutants with host-specific defects in nodulation and nitrogen fixation. J Bacteriol. 1987;169(5):2177-86 - PMID: 3032910 - PMCID: PMC212124 - DOI: 10.1128/jb.169.5.2177-2186.1987

  • Szeto WW, Nixon BT, Ronson CW, Ausubel FM Identification and characterization of the Rhizobium meliloti ntrC gene: R. meliloti has separate regulatory pathways for activation of nitrogen fixation genes in free-living and symbiotic cells. J Bacteriol. 1987;169(4):1423-32 - PMID: 2881918 - PMCID: PMC211963 - DOI: 10.1128/jb.169.4.1423-1432.1987

  • Marvel DJ, Torrey JG, Ausubel FM Rhizobium symbiotic genes required for nodulation of legume and nonlegume hosts. Proc Natl Acad Sci U S A. 1987;84(5):1319-23 - PMID: 16593814 - PMCID: PMC304419 - DOI: 10.1073/pnas.84.5.1319

  • Earl CD, Ronson CW, Ausubel FM Genetic and structural analysis of the Rhizobium meliloti fixA, fixB, fixC, and fixX genes. J Bacteriol. 1987;169(3):1127-36 - PMID: 3029021 - PMCID: PMC211910 - DOI: 10.1128/jb.169.3.1127-1136.1987

  • Buikema WJ, Klingensmith JA, Gibbons SL, Ausubel FM Conservation of structure and location of Rhizobium meliloti and Klebsiella pneumoniae nifB genes. J Bacteriol. 1987;169(3):1120-6 - PMID: 3029020 - PMCID: PMC211909 - DOI: 10.1128/jb.169.3.1120-1126.1987

  • Gussin GN, Ronson CW, Ausubel FM Regulation of nitrogen fixation genes. Annu Rev Genet. 1987;20:567-91 - PMID: 3545064 - DOI: 10.1146/annurev.ge.20.120186.003031

  • Chory J, Voytas DF, Olszewski NE, Ausubel FM Gibberellin-Induced Changes in the Populations of Translatable mRNAs and Accumulated Polypeptides in Dwarfs of Maize and Pea. Plant Physiol. 1987;83(1):15-23 - PMID: 16665192 - PMCID: PMC1056291 - DOI: 10.1104/pp.83.1.15

  • Bloch CA, Ausubel FM Paraquat-mediated selection for mutations in the manganese-superoxide dismutase gene sodA. J Bacteriol. 1986;168(2):795-8 - PMID: 3023287 - PMCID: PMC213554 - DOI: 10.1128/jb.168.2.795-798.1986

  • Nixon BT, Ronson CW, Ausubel FM Two-component regulatory systems responsive to environmental stimuli share strongly conserved domains with the nitrogen assimilation regulatory genes ntrB and ntrC. Proc Natl Acad Sci U S A. 1986;83(20):7850-4 - PMID: 3020561 - PMCID: PMC386820 - DOI: 10.1073/pnas.83.20.7850

  • Lang-Unnasch N, Dunn K, Ausubel FM Symbiotic nitrogen fixation: developmental genetics of nodule formation. Cold Spring Harb Symp Quant Biol. 1986;50:555-63 - PMID: 3868494 - DOI: 10.1101/sqb.1985.050.01.068

  • Ausubel FM Biological nitrogen fixation: recent advances and future prospects. Regul Toxicol Pharmacol. 1986;6(1):1-10 - PMID: 3704206 - DOI: 10.1016/0273-2300(86)90035-8

  • Marvel DJ, Kuldau G, Hirsch A, Richards E, Torrey JG, Ausubel FM Conservation of nodulation genes between Rhizobium meliloti and a slow-growing Rhizobium strain that nodulates a nonlegume host. Proc Natl Acad Sci U S A. 1985;82(17):5841-5 - PMID: 16593600 - PMCID: PMC390649 - DOI: 10.1073/pnas.82.17.5841

  • Buikema WJ, Szeto WW, Lemley PV, Orme-Johnson WH, Ausubel FM Nitrogen fixation specific regulatory genes of Klebsiella pneumoniae and Rhizobium meliloti share homology with the general nitrogen regulatory gene ntrC of K. pneumoniae. Nucleic Acids Res. 1985;13(12):4539-55 - PMID: 2989799 - PMCID: PMC321805 - DOI: 10.1093/nar/13.12.4539

  • Lang-Unnasch N, Ausubel FM Nodule-specific polypeptides from effective alfalfa root nodules and from ineffective nodules lacking nitrogenase. Plant Physiol. 1985;77(4):833-9 - PMID: 16664146 - PMCID: PMC1064615 - DOI: 10.1104/pp.77.4.833

  • Hirsch AM, Wilson KJ, Jones JD, Bang M, Walker VV, Ausubel FM Rhizobium meliloti nodulation genes allow Agrobacterium tumefaciens and Escherichia coli to form pseudonodules on alfalfa. J Bacteriol. 1984;158(3):1133-43 - PMID: 6327629 - PMCID: PMC215561 - DOI: 10.1128/JB.158.3.1133-1143.1984

  • Ausubel FM Regulation of nitrogen fixation genes. Cell. 1984;37(1):5-6 - PMID: 6373013 - DOI: 10.1016/0092-8674(84)90294-0

  • Szeto WW, Zimmerman JL, Sundaresan V, Ausubel FM A Rhizobium meliloti symbiotic regulatory gene. Cell. 1984;36(4):1035-43 - PMID: 6423287 - DOI: 10.1016/0092-8674(84)90053-9

  • Buikema WJ, Long SR, Brown SE, van den Bos RC, Earl C, Ausubel FM Physical and genetic characterization of Rhizobium meliloti symbiotic mutants. J Mol Appl Genet. 1984;2(3):249-60 - PMID: 6363587

  • de Bruijn FJ, Stroke IL, Marvel DJ, Ausubel FM Construction of a correlated physical and genetic map of the Klebsiella pneumoniae hisDGO region using transposon Tn5 mutagenesis. EMBO J. 1984;2(10):1831-8 - PMID: 6315405 - PMCID: PMC555367

  • Brown SE, Ausubel FM Mutations affecting regulation of the Klebsiella pneumoniae nifH (nitrogenase reductase) promotor. J Bacteriol. 1984;157(1):143-7 - PMID: 6360993 - PMCID: PMC215143 - DOI: 10.1128/JB.157.1.143-147.1984

  • Zimmerman JL, Szeto WW, Ausubel FM Molecular characterization of Tn5-induced symbiotic (Fix-) mutants of Rhizobium meliloti. J Bacteriol. 1983;156(3):1025-34 - PMID: 6196347 - PMCID: PMC217946 - DOI: 10.1128/JB.156.3.1025-1034.1983

  • Ow DW, Ausubel FM Conditionally replicating plasmid vectors that can integrate into the Klebsiella pneumoniae chromosome via bacteriophage P4 site-specific recombination. J Bacteriol. 1983;155(2):704-13 - PMID: 6307977 - PMCID: PMC217740 - DOI: 10.1128/JB.155.2.704-713.1983

  • Sundaresan V, Ow DW, Ausubel FM Activation of Klebsiella pneumoniae and Rhizobium meliloti nitrogenase promoters by gln (ntr) regulatory proteins. Proc Natl Acad Sci U S A. 1983;80(13):4030-4 - PMID: 6306658 - PMCID: PMC394194 - DOI: 10.1073/pnas.80.13.4030

  • Hirsch AM, Bang M, Ausubel FM Ultrastructural analysis of ineffective alfalfa nodules formed by nif::Tn5 mutants of Rhizobium meliloti. J Bacteriol. 1983;155(1):367-80 - PMID: 6575011 - PMCID: PMC217689 - DOI: 10.1128/JB.155.1.367-380.1983

  • Ow DW, Sundaresan V, Rothstein DM, Brown SE, Ausubel FM Promoters regulated by the glnG (ntrC) and nifA gene products share a heptameric consensus sequence in the -15 region. Proc Natl Acad Sci U S A. 1983;80(9):2524-8 - PMID: 6133280 - PMCID: PMC393858 - DOI: 10.1073/pnas.80.9.2524

  • Ruvkun GB, Long SR, Meade HM, van den Bos RC, Ausubel FM ISRm1: A Rhizobium meliloti insertion sequence that transposes preferentially into nitrogen fixation genes. J Mol Appl Genet. 1983;1(5):405-18 - PMID: 6296251

  • Sundaresan V, Jones JD, Ow DW, Ausubel FM Klebsiella pneumoniae nifA product activates the Rhizobium meliloti nitrogenase promoter. Nature. 1983;301(5902):728-32 - PMID: 6338395 - DOI: 10.1038/301728a0

  • Ow DW, Ausubel FM Regulation of nitrogen metabolism genes by nifA gene product in Klebsiella pneumoniae. Nature. 1983;301(5898):307-13 - PMID: 6337346 - DOI: 10.1038/301307a0

  • Earl CD, Ausubel FM The genetic engineering of nitrogen fixation. Nutr Rev. 1983;41(1):1-6 - PMID: 6302610 - DOI: 10.1111/j.1753-4887.1983.tb07114.x

  • Riedel GE, Brown SE, Ausubel FM Nitrogen fixation by Klebsiella pneumoniae is inhibited by certain multicopy hybrid nif plasmids. J Bacteriol. 1983;153(1):45-56 - PMID: 6336738 - PMCID: PMC217340 - DOI: 10.1128/JB.153.1.45-56.1983

  • Hirsch AM, Long SR, Bang M, Haskins N, Ausubel FM Structural studies of alfalfa roots infected with nodulation mutants of Rhizobium meliloti. J Bacteriol. 1982;151(1):411-9 - PMID: 7085566 - PMCID: PMC220253 - DOI: 10.1128/JB.151.1.411-419.1982

  • Ruvkun GB, Sundaresan V, Ausubel FM Directed transposon Tn5 mutagenesis and complementation analysis of Rhizobium meliloti symbiotic nitrogen fixation genes. Cell. 1982;29(2):551-9 - PMID: 6288262 - DOI: 10.1016/0092-8674(82)90171-4

  • Ruvkun GB, Sundaresan V, Ausubel FM Specific protection of nucleotides in the lac operator from DMS methylation and DNase I nicking by crude bacterial cell extracts. Gene. 1982;18(3):247-55 - PMID: 6290328 - DOI: 10.1016/0378-1119(82)90162-7

  • Ruvkun GB, Sundaresan V, Ausubel FM Directed transposon Tn5 mutagenesis and complementation analysis of Rhizobium meliloti symbiotic nitrogen fixation genes. Cell. 1982;29(2):551-9 - PMID: 6288262 - DOI: 10.1016/0092-8674(82)90171-4

  • Friedman AM, Long SR, Brown SE, Buikema WJ, Ausubel FM Construction of a broad host range cosmid cloning vector and its use in the genetic analysis of Rhizobium mutants. Gene. 1982;18(3):289-96 - PMID: 6290332 - DOI: 10.1016/0378-1119(82)90167-6

  • Ausubel FM Molecular genetics of symbiotic nitrogen fixation. Cell. 1982;29(1):1-2 - PMID: 6286135 - DOI: 10.1016/0092-8674(82)90082-4

  • de Bruijn FJ, Ausubel FM The cloning and transposon Tn5 mutagenesis of the glnA region of Klebsiella pneumoniae: identification of glnR, a gene involved in the regulation of the nif and hut operons. Mol Gen Genet. 1982;183(2):289-97 - PMID: 6120440 - DOI: 10.1007/BF00270631

  • Meade HM, Long SR, Ruvkun GB, Brown SE, Ausubel FM Physical and genetic characterization of symbiotic and auxotrophic mutants of Rhizobium meliloti induced by transposon Tn5 mutagenesis. J Bacteriol. 1982;149(1):114-22 - PMID: 6274841 - PMCID: PMC216598 - DOI: 10.1128/JB.149.1.114-122.1982

  • Ausubel FM, Cannon FC Molecular genetic analysis of Klebsiella pneumoniae nitrogen-fixation (nif) genes. Cold Spring Harb Symp Quant Biol. 1981;45 Pt 2:487-99 - PMID: 6266743 - DOI: 10.1101/sqb.1981.045.01.064

  • Sundaresan V, Ausubel FM Nucleotide sequence of the gene coding for the nitrogenase iron protein from Klebsiella pneumoniae. J Biol Chem. 1981;256(6):2808-12 - PMID: 6259144

  • Ow DW, Ausubel FM Recombinant P4 bacteriophages propagate as viable lytic phages or as autonomous plasmids in Klebsiella pneumoniae. Mol Gen Genet. 1981;180(1):165-75 - PMID: 6255293 - DOI: 10.1007/BF00267366

  • Ruvkun GB, Ausubel FM A general method for site-directed mutagenesis in prokaryotes. Nature. 1981;289(5793):85-8 - PMID: 6256652 - DOI: 10.1038/289085a0

  • Ruvkun GB, Ausubel FM A general method for site-directed mutagenesis in prokaryotes. Nature. 1981;289(5793):85-8 - PMID: 6256652 - DOI: 10.1038/289085a0

  • Ruvkun GB, Ausubel FM Interspecies homology of nitrogenase genes. Proc Natl Acad Sci U S A. 1980;77(1):191-5 - PMID: 6987649 - PMCID: PMC348234 - DOI: 10.1073/pnas.77.1.191

  • Ruvkun GB, Ausubel FM Interspecies homology of nitrogenase genes. Proc Natl Acad Sci U S A. 1980;77(1):191-5 - PMID: 6987649 - PMCID: PMC348234 - DOI: 10.1073/pnas.77.1.191

  • Ausubel FM, Bird SC, Durbin KJ, Janssen KA, Margolskee RF, Peskin AP Glutamine synthetase mutations which affect expression of nitrogen fixation genes in Klebsiella pneumoniae. J Bacteriol. 1979;140(2):597-606 - PMID: 40960 - PMCID: PMC216687 - DOI: 10.1128/JB.140.2.597-606.1979

  • Bedbrook JR, Lehrach H, Ausubel FM Directive segregation in the basis of colE1 plasmid incompatibility. Nature. 1979;281(5731):447-52 - PMID: 386132 - DOI: 10.1038/281447a0

  • Miller SS, Ausubel FM, Bogorad L Cyanobacterial ribonucleic acid polymerases recognize lambda promoters. J Bacteriol. 1979;140(1):246-50 - PMID: 159286 - PMCID: PMC216802 - DOI: 10.1128/JB.140.1.246-250.1979

  • Cannon FC, Riedel GE, Ausubel FM Overlapping sequences of Klebsiella pneumoniae nifDNA cloned and characterized. Mol Gen Genet. 1979;174(1):59-66 - PMID: 384162 - DOI: 10.1007/BF00433306

  • Riedel GE, Ausubel FM, Cannon FC Physical map of chromosomal nitrogen fixation (nif) genes of Klebsiella pneumoniae. Proc Natl Acad Sci U S A. 1979;76(6):2866-70 - PMID: 379866 - PMCID: PMC383710 - DOI: 10.1073/pnas.76.6.2866

  • Greer H, Ausubel FM Radiochemical identification of the kil gene product of bacteriophage lambda. Virology. 1979;95(2):577-80 - PMID: 462802 - DOI: 10.1016/0042-6822(79)90511-7

  • Cannon FC, Riedel GE, Ausubel FM Recombinant plasmid that carries part of the nitrogen fixation (nif) gene cluster of Klebsiella pneumoniae. Proc Natl Acad Sci U S A. 1977;74(7):2963-7 - PMID: 331321 - PMCID: PMC431364 - DOI: 10.1073/pnas.74.7.2963

  • Bedbrook JR, Ausubel FM Recombination between bacterial plasmids leading to the formation of plasmid multimers. Cell. 1976;9(4 PT 2):707-16 - PMID: 797459 - DOI: 10.1016/0092-8674(76)90134-3

  • Ausubel FM Radiochemical purification of bacteriophage lambda integrase. Nature. 1974;247(5437):152-4 - PMID: 4589454 - DOI: 10.1038/247152a0