Discovery of nitrate-CPK-NLP signalling in central nutrient-growth networks.

Liu KH, Niu Y, Konishi M, Wu Y, Du H, Sun Chung H, Li L, Boudsocq M, McCormack M, Maekawa S, Ishida T, Zhang C, Shokat K, Yanagisawa S, Sheen J
Nature. 2017;545(7654):311-316 - PMID: 28489820 - PMCID: PMC5823009

MAPK Assays in Arabidopsis MAMP-PRR Signal Transduction.

Chung HS, Sheen J
Methods Mol Biol. 2017;1578:155-166 - PMID: 28220422

Novel links in the plant TOR kinase signaling network.

Xiong Y, Sheen J
Curr Opin Plant Biol. 2015;28:83-91 - PMID: 26476687 - PMCID: PMC4612364

Targeted Plant Genome Editing via the CRISPR/Cas9 Technology.

Li JF, Zhang D, Sheen J
Methods Mol Biol. 2015;1284:239-55 - PMID: 25757776

Pathogen-secreted proteases activate a novel plant immune pathway.

Cheng Z, Li JF, Niu Y, Zhang XC, Woody OZ, Xiong Y, Djonovi? S, Millet Y, Bush J, McConkey BJ, Sheen J, Ausubel FM
Nature. 2015;521(7551):213-6 - PMID: 25731164 - PMCID: PMC4433409

Cas9-Based Genome Editing in Arabidopsis and Tobacco.

Li JF, Zhang D, Sheen J
Methods Enzymol. 2014;546C:459-472 - PMID: 25398353

AGROBEST: an efficient Agrobacterium-mediated transient expression method for versatile gene function analyses in Arabidopsis seedlings.

Wu HY, Liu KH, Wang YC, Wu JF, Chiu WL, Chen CY, Wu SH, Sheen J, Lai EM
Plant Methods. 2014;10:19 - PMID: 24987449 - PMCID: PMC4076510

Epinecidin-1 has immunomodulatory effects, facilitating its therapeutic use in a mouse model of Pseudomonas aeruginosa sepsis.

Pan CY, Chen JC, Sheen JF, Lin TL, Chen JY
Antimicrob Agents Chemother. 2014;58(8):4264-4274 - PMID: 24820078 - PMCID: PMC4135991

Master Regulators in Plant Glucose Signaling Networks.

Sheen J
2014;57(2):67-79 - PMID: 25530701 - PMCID: PMC4270195

Epitope-tagged protein-based artificial miRNA screens for optimized gene silencing in plants.

Li JF, Zhang D, Sheen J
Nat Protoc. 2014;9(4):939-49 - PMID: 24675734 - PMCID: PMC4208271

TOR Signaling Networks in Plant Growth and Metabolism.

Xiong Y, Sheen J
Plant Physiol. 2014;164(2):499-512 - PMID: 24385567 - PMCID: PMC3912084

Ancient signals: comparative genomics of green plant CDPKs.

Hamel LP, Sheen J, Séguin A
Trends Plant Sci. 2013;19(2):79-89 - PMID: 24342084 - PMCID: PMC3932502

Pseudomonas syringae Effector HopF2 Suppresses Arabidopsis Immunity by Targeting BAK1.

Zhou J, Wu S, Chen X, Liu C, Sheen J, Shan L, He P
Plant J. 2013;77(2):235-45 - PMID: 24237140 - PMCID: PMC4224013

The cytokinin side chain commands shooting.

Sheen J
Dev Cell. 2013;27(4):371-2 - PMID: 24286823 - PMCID: PMC3887519

Plant immune response to pathogens differs with changing temperatures.

Cheng C, Gao X, Feng B, Sheen J, Shan L, He P
Nat Commun. 2013;4:2530 - PMID: 24067909 - PMCID: PMC3901997

Dislodgement of port-A catheters in pediatric oncology patients: 11 years of experience.

Wang SC, Tsai CH, Hou CP, Lee SY, Ko SF, Hsiao CC, Chen YC, Chuang JH, Sheen JM
World J Surg Oncol. 2013;11(1):191 - PMID: 23941644 - PMCID: PMC3765137

Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9.

Li JF, Norville JE, Aach J, McCormack M, Zhang D, Bush J, Church GM, Sheen J
Nat Biotechnol. 2013;31(8):688-91 - PMID: 23929339 - PMCID: PMC4078740

Moving beyond translation: glucose-TOR signaling in the transcriptional control of cell cycle.

Xiong Y, Sheen J
Cell Cycle. 2013;12(13):1989-90 - PMID: 23759578 - PMCID: PMC3737295

The hybrid four-CBS-domain KIN?? subunit functions as the canonical ? subunit of the plant energy sensor SnRK1.

Ramon M, Ruelens P, Li Y, Sheen J, Geuten K, Rolland F
Plant J. 2013;75(1):11-25 - PMID: 23551663

Comprehensive Protein-Based Artificial MicroRNA Screens for Effective Gene Silencing in Plants.

Li JF, Chung HS, Niu Y, Bush J, McCormack M, Sheen J
Plant Cell. 2013;25(5):1507-22 - PMID: 23645631 - PMCID: PMC3694689

Glucose-TOR signalling reprograms the transcriptome and activates meristems.

Xiong Y, McCormack M, Li L, Hall Q, Xiang C, Sheen J
Nature. 2013;496(7444):181-6 - PMID: 23542588 - PMCID: PMC4140196

Phosphorylation of D-allose by hexokinase involved in regulation of OsABF1 expression for growth inhibition in Oryza sativa L.

Fukumoto T, Kano A, Ohtani K, Inoue M, Yoshihara A, Izumori K, Tajima S, Shigematsu Y, Tanaka K, Ohkouchi T, Ishida Y, Nishizawa Y, Tada Y, Ichimura K, Gomi K, Yoo SD, Sheen J, Akimitsu K
Planta. 2013;237(5):1379-91 - PMID: 23397192

Bifurcation of Arabidopsis NLR Immune Signaling via Ca(2+)-Dependent Protein Kinases.

Gao X, Chen X, Lin W, Chen S, Lu D, Niu Y, Li L, Cheng C, McCormack M, Sheen J, Shan L, He P
PLoS Pathog. 2013;9(1):e1003127 - PMID: 23382673 - PMCID: PMC3561149

Stem Cell Signaling in Immunity and Development.

Lee H, Chah OK, Plotnikov J, Sheen J
Cold Spring Harb Symp Quant Biol. 2012;77:75-81 - PMID: 23174766

CDPKs in immune and stress signaling.

Boudsocq M, Sheen J
Trends Plant Sci. 2012;18(1):30-40 - PMID: 22974587 - PMCID: PMC3534830

Complexity in Differential Peptide-Receptor Signaling: Response to Segonzac et al. and Mueller et al. Commentaries.

Lee H, Khatri A, Plotnikov JM, Zhang XC, Sheen J
Plant Cell. 2012;24(8):3177-85 - PMID: 22923676 - PMCID: PMC3462623

An interview with Jen Sheen.

Sheen J
Trends Plant Sci. 2012;17(6):321-2 - PMID: 22860262

Transient expression assays for quantifying signaling output.

Niu Y, Sheen J
Methods Mol Biol. 2012;876:195-206 - PMID: 22576097

Targeted parallel sequencing of large genetically-defined genomic regions for identifying mutations in Arabidopsis.

Liu KH, McCormack M, Sheen J
Plant Methods. 2012;8(1):12 - PMID: 22462410 - PMCID: PMC3348062

DNA purification from multiple sources in plant research with homemade silica resins.

Li JF, Sheen J
Methods Mol Biol. 2012;862:53-9 - PMID: 22419488

Rapamycin and glucose-target of rapamycin (TOR) protein signaling in plants.

Xiong Y, Sheen J
J Biol Chem. 2011;287(4):2836-42 - PMID: 22134914 - PMCID: PMC3268441

Stress-responsive mitogen-activated protein kinases interact with the EAR motif of a poplar zinc finger protein and mediate its degradation through the 26S proteasome.

Hamel LP, Benchabane M, Nicole MC, Major IT, Morency MJ, Pelletier G, Beaudoin N, Sheen J, Séguin A
Plant Physiol. 2011;157(3):1379-93 - PMID: 21873571 - PMCID: PMC3252155

Protein kinase signaling networks in plant innate immunity.

Tena G, Boudsocq M, Sheen J
Curr Opin Plant Biol. 2011;14(5):519-29 - PMID: 21704551 - PMCID: PMC3191242

Stem-cell-triggered immunity through CLV3p-FLS2 signalling.

Lee H, Chah OK, Sheen J
Nature. 2011;473(7347):376-9 - PMID: 21499263 - PMCID: PMC3098311

Discover and connect cellular signaling.

Sheen J
Plant Physiol. 2010;154(2):562-6 - PMID: 20921185 - PMCID: PMC2949017

Differential innate immune signalling via Ca(2+) sensor protein kinases.

Boudsocq M, Willmann MR, McCormack M, Lee H, Shan L, He P, Bush J, Cheng SH, Sheen J
Nature. 2010;464(7287):418-22 - PMID: 20164835 - PMCID: PMC2841715

Protocol: a rapid and economical procedure for purification of plasmid or plant DNA with diverse applications in plant biology.

Li JF, Li L, Sheen J
Plant Methods. 2010;6(1):1 - PMID: 20180960 - PMCID: PMC2829548

Low glucose uncouples hexokinase1-dependent sugar signaling from stress and defense hormone abscisic acid and C2H4 responses in Arabidopsis.

Cho YH, Sheen J, Yoo SD
Plant Physiol. 2009;152(3):1180-2 - PMID: 20034964 - PMCID: PMC2832269

In vitro reconstitution of an abscisic acid signalling pathway.

Fujii H, Chinnusamy V, Rodrigues A, Rubio S, Antoni R, Park SY, Cutler SR, Sheen J, Rodriguez PL, Zhu JK
Nature. 2009;462(7273):660-4 - PMID: 19924127 - PMCID: PMC2803041

Emerging connections in the ethylene signaling network.

Yoo SD, Cho Y, Sheen J
Trends Plant Sci. 2009;14(5):270-9 - PMID: 19375376 - PMCID: PMC3063992

Sugar sensing and signaling.

Ramon M, Rolland F, Sheen J
Arabidopsis Book. 2008;6:e0117 - PMID: 22303242 - PMCID: PMC3243355

Convergent energy and stress signaling.

Baena-González E, Sheen J
Trends Plant Sci. 2008;13(9):474-82 - PMID: 18701338 - PMCID: PMC3075853

Bacterial effectors target the common signaling partner BAK1 to disrupt multiple MAMP receptor-signaling complexes and impede plant immunity.

Shan L, He P, Li J, Heese A, Peck SC, Nürnberger T, Martin GB, Sheen J
Cell Host Microbe. 2008;4(1):17-27 - PMID: 18621007 - PMCID: PMC2830012

Expression and evolutionary features of the hexokinase gene family in Arabidopsis.

Karve A, Rauh BL, Xia X, Kandasamy M, Meagher RB, Sheen J, Moore BD
Planta. 2008;228(3):411-25 - PMID: 18481082 - PMCID: PMC2953952

Cytokinin and auxin interaction in root stem-cell specification during early embryogenesis.

Müller B, Sheen J
Nature. 2008;453(7198):1094-7 - PMID: 18463635 - PMCID: PMC2601652

Dual control of nuclear EIN3 by bifurcate MAPK cascades in C2H4 signalling.

Yoo SD, Cho YH, Tena G, Xiong Y, Sheen J
Nature. 2008;451(7180):789-95 - PMID: 18273012 - PMCID: PMC3488589

Pseudomonas syringae type III effector AvrRpt2 alters Arabidopsis thaliana auxin physiology.

Chen Z, Agnew JL, Cohen JD, He P, Shan L, Sheen J, Kunkel BN
Proc Natl Acad Sci U S A. 2007;104(50):20131-6 - PMID: 18056646 - PMCID: PMC2148434

Arabidopsis cytokinin signaling pathway.

Müller B, Sheen J
Sci STKE. 2007;2007(407):cm5 - PMID: 17925576

Cytokinin signaling pathway.

Müller B, Sheen J
Sci STKE. 2007;2007(407):cm4 - PMID: 17925575

Advances in cytokinin signaling.

Müller B, Sheen J
Science. 2007;318(5847):68-9 - PMID: 17916725

The N-terminal region of Pseudomonas type III effector AvrPtoB elicits Pto-dependent immunity and has two distinct virulence determinants.

Xiao F, He P, Abramovitch RB, Dawson JE, Nicholson LK, Sheen J, Martin GB
Plant J. 2007;52(4):595-614 - PMID: 17764515 - PMCID: PMC2265002

A central integrator of transcription networks in plant stress and energy signalling.

Baena-González E, Rolland F, Thevelein JM, Sheen J
Nature. 2007;448(7156):938-42 - PMID: 17671505

Arabidopsis mesophyll protoplasts: a versatile cell system for transient gene expression analysis.

Yoo SD, Cho YH, Sheen J
Nat Protoc. 2007;2(7):1565-72 - PMID: 17585298

Intercepting host MAPK signaling cascades by bacterial type III effectors.

Shan L, He P, Sheen J
Cell Host Microbe. 2007;1(3):167-74 - PMID: 18005696

Elicitation and suppression of microbe-associated molecular pattern-triggered immunity in plant-microbe interactions.

He P, Shan L, Sheen J
Cell Microbiol. 2007;9(6):1385-96 - PMID: 17451411

Nuclear actions in innate immune signaling.

Sheen J, He P
Cell. 2007;128(5):821-3 - PMID: 17350565

Glucose signaling through nuclear hexokinase1 complex in Arabidopsis.

Cho YH, Yoo SD, Sheen J
Plant Signal Behav. 2007;2(2):123-4 - PMID: 19704756 - PMCID: PMC2633915

The use of protoplasts to study innate immune responses.

He P, Shan L, Sheen J
Methods Mol Biol. 2006;354:1-9 - PMID: 17172739

Regulatory functions of nuclear hexokinase1 complex in glucose signaling.

Cho YH, Yoo SD, Sheen J
Cell. 2006;127(3):579-89 - PMID: 17081979

Sugar sensing and signaling in plants: conserved and novel mechanisms.

Rolland F, Baena-Gonzalez E, Sheen J
Annu Rev Plant Biol. 2006;57:675-709 - PMID: 16669778

Specific bacterial suppressors of MAMP signaling upstream of MAPKKK in Arabidopsis innate immunity.

He P, Shan L, Lin NC, Martin GB, Kemmerling B, Nürnberger T, Sheen J
Cell. 2006;125(3):563-75 - PMID: 16678099

Ancient signals: comparative genomics of plant MAPK and MAPKK gene families.

Hamel LP, Nicole MC, Sritubtim S, Morency MJ, Ellis M, Ehlting J, Beaudoin N, Barbazuk B, Klessig D, Lee J, Martin G, Mundy J, Ohashi Y, Scheel D, Sheen J, Xing T, Zhang S, Seguin A, Ellis BE
Trends Plant Sci. 2006;11(4):192-8 - PMID: 16537113

Sugar sensing and signalling networks in plants.

Rolland F, Sheen J
Biochem Soc Trans. 2005;33(Pt 1):269-71 - PMID: 15667323

Expression of an active tobacco mitogen-activated protein kinase kinase kinase enhances freezing tolerance in transgenic maize.

Shou H, Bordallo P, Fan JB, Yeakley JM, Bibikova M, Sheen J, Wang K
Proc Natl Acad Sci U S A. 2004;101(9):3298-303 - PMID: 14960727 - PMCID: PMC365784

Differential regulation of EIN3 stability by glucose and ethylene signalling in plants.

Yanagisawa S, Yoo SD, Sheen J
Nature. 2003;425(6957):521-5 - PMID: 14523448

Role of the Arabidopsis glucose sensor HXK1 in nutrient, light, and hormonal signaling.

Moore B, Zhou L, Rolland F, Hall Q, Cheng WH, Liu YX, Hwang I, Jones T, Sheen J
Science. 2003;300(5617):332-6 - PMID: 12690200

Sugar and hormone connections.

León P, Sheen J
Trends Plant Sci. 2003;8(3):110-6 - PMID: 12663220

A unique short-chain dehydrogenase/reductase in Arabidopsis glucose signaling and abscisic acid biosynthesis and functions.

Cheng WH, Endo A, Zhou L, Penney J, Chen HC, Arroyo A, Leon P, Nambara E, Asami T, Seo M, Koshiba T, Sheen J
Plant Cell. 2002;14(11):2723-43 - PMID: 12417697 - PMCID: PMC152723

Sugar sensing and signaling in plants.

Rolland F, Moore B, Sheen J
Plant Cell. 2002;14 Suppl:S185-205 - PMID: 12045277 - PMCID: PMC151255

Calcium signaling through protein kinases. The Arabidopsis calcium-dependent protein kinase gene family.

Cheng SH, Willmann MR, Chen HC, Sheen J
Plant Physiol. 2002;129(2):469-85 - PMID: 12068094 - PMCID: PMC1540234

Two-component signal transduction pathways in Arabidopsis.

Hwang I, Chen HC, Sheen J
Plant Physiol. 2002;129(2):500-15 - PMID: 12068096 - PMCID: PMC161668

Phosphorelay and transcription control in cytokinin signal transduction.

Sheen J
Science. 2002;296(5573):1650-2 - PMID: 12040183

MAP kinase signalling cascade in Arabidopsis innate immunity.

Asai T, Tena G, Plotnikova J, Willmann MR, Chiu WL, Gomez-Gomez L, Boller T, Ausubel FM, Sheen J
Nature. 2002;415(6875):977-83 - PMID: 11875555

Signal transduction in maize and Arabidopsis mesophyll protoplasts.

Sheen J
Plant Physiol. 2001;127(4):1466-75 - PMID: 11743090 - PMCID: PMC1540179

Dissection of abscisic acid signal transduction pathways in barley aleurone layers.

Shen Q, Gomez-Cadenas A, Zhang P, Walker-Simmons MK, Sheen J, Ho TH
Plant Mol Biol. 2001;47(3):437-48 - PMID: 11587514

Plant mitogen-activated protein kinase signaling cascades.

Tena G, Asai T, Chiu WL, Sheen J
Curr Opin Plant Biol. 2001;4(5):392-400 - PMID: 11597496

Two-component circuitry in Arabidopsis cytokinin signal transduction.

Hwang I, Sheen J
Nature. 2001;413(6854):383-9 - PMID: 11574878

Molecular identification of phenylalanine ammonia-lyase as a substrate of a specific constitutively active Arabidopsis CDPK expressed in maize protoplasts.

Cheng SH, Sheen J, Gerrish C, Bolwell GP
FEBS Lett. 2001;503(2-3):185-8 - PMID: 11513879

Isotopic assays for reporter gene activity.

Kingston RE, Sheen J, Moore D
Curr Protoc Pharmacol. 2001;Chapter 6:Unit 6.4 - PMID: 21965075

Isotopic assays for reporter gene activity.

Kingston RE, Sheen J, Moore D
Curr Protoc Mol Biol. 2001;Chapter 9:Unit9.7A - PMID: 18265285

Introduction of plasmid DNA into cells.

Seidman CE, Struhl K, Sheen J, Jessen T
Curr Protoc Mol Biol. 2001;Chapter 1:Unit1.8 - PMID: 18265047

Mesophyll-specific, light and metabolic regulation of the C4 PPCZm1 promoter in transgenic maize.

Kausch AP, Owen TP, Zachwieja SJ, Flynn AR, Sheen J
Plant Mol Biol. 2001;45(1):1-15 - PMID: 11247600

The role of hexokinase in plant sugar signal transduction and growth and development.

Xiao W, Sheen J, Jang JC
Plant Mol Biol. 2000;44(4):451-61 - PMID: 11197321

Fumonisin B1-induced cell death in arabidopsis protoplasts requires jasmonate-, ethylene-, and salicylate-dependent signaling pathways.

Asai T, Stone JM, Heard JE, Kovtun Y, Yorgey P, Sheen J, Ausubel FM
Plant Cell. 2000;12(10):1823-36 - PMID: 11041879 - PMCID: PMC149122

Analysis of Arabidopsis glucose insensitive mutants, gin5 and gin6, reveals a central role of the plant hormone ABA in the regulation of plant vegetative development by sugar.

Arenas-Huertero F, Arroyo A, Zhou L, Sheen J, León P
Genes Dev. 2000;14(16):2085-96 - PMID: 10950871 - PMCID: PMC316855


Sheen J
Annu Rev Plant Physiol Plant Mol Biol. 1999;50():187-217 - PMID: 15012208

Feedback control of gene expression.

Sheen J
Photosynth Res. 1994;39(3):427-38 - PMID: 24311134

Differential Expression in Bundle Sheath and Mesophyll Cells of Maize of Genes for Photosystem II Components Encoded by the Plastid Genome.

Sheen JY, Bogorad L
Plant Physiol. 1988;86(4):1020-6 - PMID: 16666025 - PMCID: PMC1054621

Differential expression of oxygen-evolving polypeptide genes in maize leaf cell types.

Sheen JY, Sayre RT, Bogorad L
Plant Mol Biol. 1987;9(3):217-26 - PMID: 24276970

Regulation of levels of nuclear transcripts for C4 photosynthesis in bundle sheath and mesophyll cells of maize leaves.

Sheen JY, Bogorad L
Plant Mol Biol. 1987;8(3):227-38 - PMID: 24301127

Expression of the ribulose-1,5-bisphosphate carboxylase large subunit gene and three small subunit genes in two cell types of maize leaves.

Sheen JY, Bogorad L
EMBO J. 1986;5(13):3417-22 - PMID: 16453739 - PMCID: PMC1167374

Differential expression of the ribulose bisphosphate carboxylase large subunit gene in bundle sheath and mesophyll cells of developing maize leaves is influenced by light.

Sheen JY, Bogorad L
Plant Physiol. 1985;79(4):1072-6 - PMID: 16664532 - PMCID: PMC1075029

Unequal crossing-over associated with asymmetrical synapsis between nomadic elements in the Drosophila melanogaster genome.

Goldberg ML, Sheen JY, Gehring WJ, Green MM
Proc Natl Acad Sci U S A. 1983;80(16):5017-21 - PMID: 16593354 - PMCID: PMC384179