Publications - Hung - 2024
Romano KP, Bagnall J, Warrier T, Sullivan J, Ferrara K, Orzechowski M, Nguyen PH, Raines K, Livny J, Shoresh N, Hung DT Perturbation-specific transcriptional mapping for unbiased target elucidation of antibiotics. Proc Natl Acad Sci U S A. 2024;121(45):e2409747121 - PMID: 39467118 - PMCID: PMC11551328 - DOI: 10.1073/pnas.2409747121
Parada-Kusz M, Clatworthy AE, Goering ER, Blackwood SM, Shigeta JY, Mashin E, Salm EJ, Choi C, Combs S, Lee JSW, Rodriguez-Osorio C, Clish C, Tomita S, Hung DT 3-Hydroxykynurenine targets kainate receptors to promote defense against infection. Nat Chem Biol. 2024;:ePub - PMID: 38898166 - DOI: 10.1038/s41589-024-01635-z
Romano KP, Bagnall J, Warrier T, Sullivan J, Ferrara K, Orzechowski M, Nguyen PH, Raines K, Livny J, Shoresh N, Hung DT Perturbation-Specific Transcriptional Mapping facilitates unbiased target elucidation of antibiotics. bioRxiv. 2024;:ePub - PMID: 38712067 - PMCID: PMC11071498 - DOI: 10.1101/2024.04.25.590978
Poulsen BE, Warrier T, Barkho S, Bagnall J, Romano KP, White T, Yu X, Kawate T, Nguyen PH, Raines K, Ferrara K, Golas A, Fitzgerald M, Boeszoermenyi A, Kaushik V, Serrano-Wu M, Shoresh N, Hung DT "Multiplexed screen identifies a Pseudomonas aeruginosa -specific small molecule targeting the outer membrane protein OprH and its interaction with LPS". bioRxiv. 2024;:ePub - PMID: 38559044 - PMCID: PMC10980007 - DOI: 10.1101/2024.03.16.585348
Neo DM, Clatworthy AE, Hung DT A dual-plasmid CRISPR/Cas9-based method for rapid and efficient genetic disruption in Mycobacterium abscessus. J Bacteriol. 2024;206(3):e0033523 - PMID: 38319218 - PMCID: PMC10955840 - DOI: 10.1128/jb.00335-23
Sturm A, Sun P, Avila-Pacheco J, Clatworthy AE, Bloom-Ackermann Z, Wuo MG, Gomez JE, Jin S, Clish CB, Kiessling LL, Hung DT Genetic factors affecting storage and utilization of lipids during dormancy in Mycobacterium tuberculosis. MBio. 2024;15(2):e0320823 - PMID: 38236034 - PMCID: PMC10865790 - DOI: 10.1128/mbio.03208-23