Marco Colonna, MD, is an Investigator at Massachusetts General Hospital, an institute member of the Broad Institute of MIT and Harvard, and a member of the Center for Integrated Solutions for Infectious Diseases since 2026 following an extensive tenure as a professor at Washington University School of Medicine in St. Louis. He trained in internal medicine at the University of Parma, Italy, and is a leading and highly cited immunologist recognized for the breadth of his research and his innovative contributions to the field.

He has made foundational contributions to the understanding of innate immunity, including the discovery of innate lymphoid cells, plasmacytoid dendritic cells, the TREM receptor family, and leukocyte immunoglobulin-like receptors (LILRs). He is the senior author of more than 150 original research articles and over 120 reviews and commentaries, and his work has been cited more than 140,000 times. His current research spans mucosal immunology, cancer immunology, neuroimmunology and neurodegeneration. He is an elected member of the National Academy of Sciences and the American Academy of Arts and Sciences.