Publications for All Faculty

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Tanoue T, Nagayama M, Roochana AJA, Zimmerman S, Ashenberg O, Jain T, Igarashi R, Sasajima S, Takeshita K, Hetherington N, Okahashi N, Ueda M, Konishi M, Nakayama Y, Minoda A, Skelly AN, Minokoshi Y, Pucci N, Mende DR, Arita M, Yamamoto H, Watanabe S, Miura K, Behie SW, Suda W, Sato T, Atarashi K, Matsushita M, Kajimura S, Plichta DR, Saito M, Xavier RJ, Honda K

Microbiota-mediated induction of beige adipocytes in response to dietary cues.
Nature. 2026;:ePub - PMID: 41781619 - PMCID: PMC13051337 - DOI: 10.1038/s41586-026-10205-3

Fiskin E, Eraslan G, Alora-Palli MB, Jain T, Leyva-Castillo JM, Kim S, Choe H, Lareau CA, Lau H, Finan EP, Teixeira-Soldano I, LaBere B, Chu A, Woods B, Chou J, Slyper M, Waldman J, Islam S, Schneider L, Phipatanakul W, Platt C, Rozenblatt-Rosen O, Delorey TM, Ashenberg O, Deguine J, Smith GP, Geha RS, Regev A, Xavier RJ

Multi-modal skin atlas identifies a multicellular immune-stromal community associated with disrupted cornification and specific T cell expansion in atopic dermatitis.
Nat Commun. 2026;17(1):ePub - PMID: 41741455 - PMCID: PMC13057205 - DOI: 10.1038/s41467-026-69587-7

Thurimella K, Wu E, Li C, Graham DB, Owens RM, Plichta DR, Sokol CL, Xavier RJ, Bacallado S

Identifying microbial protease allergens through protein language model-guided homology.
Cell Syst. 2026;17(3):101510 - PMID: 41722567 - PMCID: PMC13015258 - DOI: 10.1016/j.cels.2025.101510

Jaiswal A, Kooistra T, Pokatayev V, Bastos HN, Santos RF, Sarraf TR, Segerstolpe Å, Lin C, Amir-Zilberstein L, Twardus S, Shannon K, Murphy SP, Knipe R, Ganzleben IK, Black KE, Delorey TM, Graham DB, Hung YP, Hariri LP, Deguine J, Carvalho A, Medoff BD, Xavier RJ

Spatial transcriptomics reveals altered communities and drivers of aberrant epithelia and pro-fibrotic fibroblasts in interstitial lung diseases.
Cell Genom. 2026;6(3):101066 - PMID: 41576947 - PMCID: PMC12985369 - DOI: 10.1016/j.xgen.2025.101066

Rush JS, Wertheimer JD, Goldberg SD, Raymond D, Szuchnicki M, Baltus AJ, Branson J, Stratton CF, Patrick AN, Steele R, Adhikary S, Del Rosario A, Liu A, Gomersall NJ, Chung M, Ranaghan MJ, Gu X, Brandt M, Cao Z, Bebenek A, Oliver BA, Hoebe K, Szewczuk LM, Venable JD, Graham DB, Towne J, Xavier RJ

Human genetics guides the discovery of CARD9 inhibitors with anti-inflammatory activity.
Cell. 2026;189(5):1356-1370.e26 - PMID: 41547356 - PMCID: PMC12817910 - DOI: 10.1016/j.cell.2025.12.013

Ashenberg O, Xavier RJ

Bridging AI and biology: Foundation models meet human physiology and disease.
Med. 2026;7(1):100971 - PMID: 41519120 - DOI: 10.1016/j.medj.2025.100971

Pokatayev V, Jaiswal A, Shih AR, Segerstolpe Å, Li B, Creasey EA, Zhao Y, Lin C, Murphy S, Chou CH, Graham DB, Xavier RJ

Bidirectional CRISPR screens decode a GLIS3-dependent fibrotic cell circuit.
Nature. 2026;650(8103):997-1006 - PMID: 41501466 - PMCID: PMC12820784 - DOI: 10.1038/s41586-025-09907-x
Total: 7