Publications for All Faculty - 2022

  • Warrier T, Romano KP, Clatworthy AE, Hung DT Integrated genomics and chemical biology herald an era of sophisticated antibacterial discovery, from defining essential genes to target elucidation. Cell Chem Biol. 2022;29(5):716-729 - PMID: 35523184 - DOI: 10.1016/j.chembiol.2022.04.006

  • Thakku SG, Ackerman CM, Myhrvold C, Bhattacharyya RP, Livny J, Ma P, Gomez GI, Sabeti PC, Blainey PC, Hung DT Multiplexed detection of bacterial nucleic acids using Cas13 in droplet microarrays. PNAS Nexus. 2022;1(1):pgac021 - PMID: 35450424 - PMCID: PMC9013781 - DOI: 10.1093/pnasnexus/pgac021

  • Zhang SJ, Duzdevich D, Ding D, Szostak JW Freeze-thaw cycles enable a prebiotically plausible and continuous pathway from nucleotide activation to nonenzymatic RNA copying. Proc Natl Acad Sci U S A. 2022;119(17):e2116429119 - PMID: 35446612 - DOI: 10.1073/pnas.2116429119

  • Johannes F. Scheid, Basak Eraslan, Andrew Hudak, Eric Brown, Dallis Sergio, Toni Delorey, Devan Phillips, Ariel Lefkovith, Alison T. Jess, Lennard W. Duck, Charles O. Elson, Hera Vlamakis, Jacques Deguine, Ashwin Ananthakrishnan, Daniel B. Graham, Aviv Regev, Ramnik J. Xavier Remodeling of human colon plasma cell repertoire in ulcerative colitis. bioRxiv. 2022;:ePub - DOI: https://doi.org/10.1101/2022.02.14.480403

  • Szamosvári D, Bae M, Bang S, Tusi BK, Cassilly CD, Park SM, Graham DB, Xavier RJ, Clardy J Lyme Disease, Borrelia burgdorferi, and Lipid Immunogens. J Am Chem Soc. 2022;144(6):2474-2478 - PMID: 35129341 - DOI: 10.1021/jacs.1c12202

  • Jasso GJ, Jaiswal A, Varma M, Laszewski T, Grauel A, Omar A, Silva N, Dranoff G, Porter JA, Mansfield K, Cremasco V, Regev A, Xavier RJ, Graham DB Colon stroma mediates an inflammation-driven fibroblastic response controlling matrix remodeling and healing. PLoS Biol. 2022;20(1):e3001532 - PMID: 35085231 - PMCID: PMC8824371 - DOI: 10.1371/journal.pbio.3001532

  • Radakovic A, DasGupta S, Wright TH, Aitken HRM, Szostak JW Nonenzymatic assembly of active chimeric ribozymes from aminoacylated RNA oligonucleotides. Proc Natl Acad Sci U S A. 2022;119(7):ePub - PMID: 35140183 - PMCID: PMC8851484 - DOI: 10.1073/pnas.2116840119

  • Ding D, Zhou L, Giurgiu C, Szostak JW Kinetic explanations for the sequence biases observed in the nonenzymatic copying of RNA templates. Nucleic Acids Res. 2022;50(1):35-45 - PMID: 34893864 - PMCID: PMC8754633 - DOI: 10.1093/nar/gkab1202

  • Poulsen BE, Clatworthy AE, Hung DT The Use of Tn-Seq and the FiTnEss Analysis to Define the Core Essential Genome of Pseudomonas aeruginosa. Methods Mol Biol. 2022;2377:179-197 - PMID: 34709617 - DOI: 10.1007/978-1-0716-1720-5_10