Publications for All Faculty
Mitochondrial dysfunction induces RNA interference in C. elegans through a pathway homologous to the mammalian RIG-I antiviral response.
TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41.
Plasma proteomics reveals tissue-specific cell death and mediators of cell-cell interactions in severe COVID-19 patients.
Generation of Fluorinated Amychelin Siderophores against Pseudomonas aeruginosa Infections by a Combination of Genome Mining and Mutasynthesis.
TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41.
A missense variant in SLC39A8 confers risk for Crohn's disease by disrupting manganese homeostasis and intestinal barrier integrity.
Multi-biomarker Prediction Models for Multiple Infection Episodes Following Blunt Trauma.
USP15 Deubiquitinates CARD9 to Downregulate C-Type Lectin Receptor-Mediated Signaling.
Solid-Phase Synthesis of Sequence-Defined Informational Oligomers.
In the Model Host Caenorhabditis elegans, Sphingosine-1-Phosphate-Mediated Signaling Increases Immunity toward Human Opportunistic Bacteria.
Nanopore sequencing at Mars, Europa, and microgravity conditions.
Nonenzymatic RNA-templated Synthesis of N3'→P5' Phosphoramidate DNA.
Multi-"-Omics" Profiling in Patients With Quiescent Inflammatory Bowel Disease Identifies Biomarkers Predicting Relapse.
Potentially Prebiotic Activation Chemistry Compatible with Nonenzymatic RNA Copying.
Assembly of a ribozyme ligase from short oligomers by nonenzymatic ligation.
Linking strain engraftment in fecal microbiota transplantation with maintenance of remission in Crohn's disease.
The Human and Mouse Enteric Nervous System at Single-Cell Resolution.
Technologies and Computational Analysis Strategies for CRISPR Applications.
Growth and the Microbiome - Integrating Global Health with Basic Science.
Beth Cindy Levine (1960-2020).
Lysosomal activity regulates Caenorhabditis elegans mitochondrial dynamics through vitamin B12 metabolism.
Characterization of Five Novel Anti-MRSA Compounds Identified Using a Whole-Animal Caenorhabditis elegans/Galleria mellonella Sequential-Screening Approach.
Genome and sequence determinants governing the expression of horizontally acquired DNA in bacteria.
Response to Comment on "RNA-guided DNA insertion with CRISPR-associated transposases".
A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing.
Template-directed copying of RNA by non-enzymatic ligation.
Cholesterol Metabolism by Uncultured Human Gut Bacteria Influences Host Cholesterol Level.
Cell Type- and Stimulation-Dependent Transcriptional Programs Regulated by Atg16L1 and Its Crohn's Disease Risk Variant T300A.
The Neutrally Charged Diarylurea Compound PQ401 Kills Antibiotic-Resistant and Antibiotic-Tolerant Staphylococcus aureus.
Bulk Self-Assembly of Giant, Unilamellar Vesicles.
A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors.
Deep sequencing of non-enzymatic RNA primer extension.
Adaptive evolution of virulence and persistence in carbapenem-resistant Klebsiella pneumoniae.
Ultraviolet-Driven Deamination of Cytidine Ribonucleotides Under Planetary Conditions.
Massively multiplexed nucleic acid detection with Cas13.
Synthesis of phosphoramidate-linked DNA by a modified DNA polymerase.
Megakaryocytes contain extranuclear histones and may be a source of platelet-associated histones during sepsis.
Defining trained immunity and its role in health and disease.
Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons.
In vitro selection of ribozyme ligases that use prebiotically plausible 2-aminoimidazole-activated substrates.
Pathway paradigms revealed from the genetics of inflammatory bowel disease.
Global chemical effects of the microbiome include new bile-acid conjugations.
An immune-cell signature of bacterial sepsis.
Primary nitrate responses via calcium signalling and diverse protein phosphorylation.
Intestinal microbes influence development of thymic lymphocytes in early life.
Growth effects of N-acylethanolamines on gut bacteria reflect altered bacterial abundances in inflammatory bowel disease.
Translation and Cross-Cultural Validation of the English Young Adult Burn Outcome Questionnaire (YABOQ) in Spanish.
A model for the emergence of RNA from a prebiotically plausible mixture of ribonucleotides, arabinonucleotides and 2'-deoxynucleotides.
Large phenotypic enhancement of structured random RNA pools.
A Twelve-Week, Randomized, Double-Blind, Placebo-Controlled, Four-Arm Dose-Finding Phase 2 Study Evaluating Bexagliflozin as a Monotherapy for Adults with Type 2 Diabetes.
A large-scale chemical-genetic strategy enables design of antimicrobial combination chemotherapy in Mycobacteria.
Use of narrative concepts in the EHR to validate genetic determinants of treatment response in a virtual inflammatory bowel disease cohort.
Prospective Validation of a Transcriptomic Metric in Severe Trauma.
