Publications for All Faculty
Hybridization-based capture of pathogen mRNA enables paired host-pathogen transcriptional analysis.
Genome-wide comparisons of gene expression in adult versus elderly burn patients.
Comprehensive analysis of chromosomal mobile genetic elements in the gut microbiome reveals phylum-level niche-adaptive gene pools.
The Pseudomonas aeruginosa accessory genome elements influence virulence towards Caenorhabditis elegans.
Simultaneous detection of genotype and phenotype enables rapid and accurate antibiotic susceptibility determination.
Non-enzymatic primer extension with strand displacement.
Associations between clinical characteristics and the development of multiple organ failure after severe burns in adult patients.
Lipid constituents of model protocell membranes.
Model-driven discovery of calcium-related protein-phosphatase inhibition in plant guard cell signaling.
Prebiotically Plausible 'Patching' of RNA Backbone Cleavage Through a 3'-5' Pyrophosphate Linkage.
A point of inflection and reflection on systems chemical biology.
ROS-based lethality of Caenorhabditis elegans mitochondrial electron transport mutants grown on Escherichia coli siderophore iron release mutants.
Transcriptional Atlas of Intestinal Immune Cells Reveals that Neuropeptide α-CGRP Modulates Group 2 Innate Lymphoid Cell Responses.
CRISPR DNA base editors with reduced RNA off-target and self-editing activities.
Developing Effective Alzheimer's Disease Therapies: Clinical Experience and Future Directions.
Distinct Tissue-Specific Roles for the Disease-Associated Autophagy Genes ATG16L2 and ATG16L1.
DNA polymerase activity on synthetic N3'→P5' phosphoramidate DNA templates.
Cytokine release and gastrointestinal symptoms after gluten challenge in celiac disease.
UV photostability of three 2-aminoazoles with key roles in prebiotic chemistry on the early earth.
Therapeutic Opportunities in Inflammatory Bowel Disease: Mechanistic Dissection of Host-Microbiome Relationships.
A selective membrane-targeting repurposed antibiotic with activity against persistent methicillin-resistant Staphylococcus aureus.
Predictive metabolomic profiling of microbial communities using amplicon or metagenomic sequences.
Template-directed Nonenzymatic Primer Extension Using 2-methylimidazole-activated Morpholino Derivatives of Guanosine and Cytidine.
A 96-Week Multinational Randomized Double-Blind Parallel-Group Clinical Trial Evaluating the Safety and Effectiveness of Bexagliflozin as a Monotherapy for Adults with Type 2 Diabetes.
Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss.
Default Activation and Nuclear Translocation of the Plant Cellular Energy Sensor SnRK1 Regulate Metabolic Stress Responses and Development.
Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis.
Case 22-2019: A 65-Year-Old Woman with Weakness, Dark Urine, and Dysphagia.
Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis.
Microbial genes and pathways in inflammatory bowel disease.
Mutations in pmrB confer cross-resistance between the LptD inhibitor POL7080 and colistin in Pseudomonas aeruginosa.
Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.
Nucleic Acid Extraction and Sequencing from Low-Biomass Synthetic Mars Analog Soils for In Situ Life Detection.
Nonenzymatic template-directed synthesis of mixed-sequence 3'-NP-DNA up to 25 nucleotides long inside model protocells.
Ruminococcus gnavus, a member of the human gut microbiome associated with Crohn's disease, produces an inflammatory polysaccharide.
RNA-guided DNA insertion with CRISPR-associated transposases.
A 24-week, randomized, double-blind, active-controlled clinical trial comparing bexagliflozin to sitagliptin as an adjunct to metformin for the treatment of type 2 diabetes in adults.
Regulation of Caenorhabditis elegans neuronal polarity by heterochronic genes.
Akkermansia muciniphila induces intestinal adaptive immune responses during homeostasis.
Correction: Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population.
Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases.
Conservation of the structure and function of bacterial tryptophan synthases.
Induction of the metal transporter ZIP8 by interferon gamma in intestinal epithelial cells: Potential role of metal dyshomeostasis in Crohn's disease.
Safety and Effectiveness of Bexagliflozin in Patients With Type 2 Diabetes Mellitus and Stage 3a/3b CKD.
Default activation and nuclear translocation of the plant cellular energy sensor SnRK1 regulate metabolic stress responses and development.
Meiotic gatekeeper STRA8 suppresses autophagy by repressing Nr1d1 expression during spermatogenesis in mice.
Bacteroides-Derived Sphingolipids Are Critical for Maintaining Intestinal Homeostasis and Symbiosis.
Publisher Correction: Definitions and guidelines for research on antibiotic persistence.
Defining the core essential genome of Pseudomonas aeruginosa.
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis.
Tetraspanin CD82 Organizes Dectin-1 into Signaling Domains to Mediate Cellular Responses to Candida albicans.
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors.
Adaptive Evolution within Gut Microbiomes of Healthy People.
Endoplasmic reticulum-associated SKN-1A/Nrf1 mediates a cytoplasmic unfolded protein response and promotes longevity.
Gut Microbial Associations to Plasma Metabolites Linked to Cardiovascular Phenotypes and Risk: A Cross-Sectional Study.
Author Correction: Gut microbiome structure and metabolic activity in inflammatory bowel disease.
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression.
Gut Microbiota Regulation of T Cells During Inflammation and Autoimmunity.
Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study.
The mechanism of nonenzymatic template copying with imidazole-activated nucleotides.
Molybdenum cofactor transfer from bacteria to nematode mediates sulfite detoxification.
Rapid identification and phylogenetic classification of diverse bacterial pathogens in a multiplexed hybridization assay targeting ribosomal RNA.
Transfer of Sequence Information and Replication of Diimine Duplexes.
Salt-Inducible Kinases: Physiology, Regulation by cAMP, and Therapeutic Potential: (Trends Endocrinol. Metab. 29, 723-735, 2018).
Adopt a moratorium on heritable genome editing.
CRISPResso2 provides accurate and rapid genome editing sequence analysis.
Mitochondrial Dysfunction in C. elegans Activates Mitochondrial Relocalization and Nuclear Hormone Receptor-Dependent Detoxification Genes.
Engineered CRISPR-Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing.
Spatial and Temporal Mapping of Human Innate Lymphoid Cells Reveals Elements of Tissue Specificity.
Rhizobium induces DNA damage in Caenorhabditis elegans intestinal cells.
Integration of nutrient, energy, light and hormone signalling via TOR in plants.
SLC39A8 missense variant is associated with Crohn's disease but does not have a major impact on gut microbiome composition in healthy subjects.
Single-Cell RNA Sequencing to Understand Host-Pathogen Interactions.
Using Imaging Flow Cytometry to Quantify and Optimize Giant Vesicle Production by Water-in-oil Emulsion Transfer Methods.
A defined commensal consortium elicits CD8 T cells and anti-cancer immunity.
Engineering of CRISPR-Cas12b for human genome editing.
The Crohn's disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response.
Noncanonical ATG8-ABS3 interaction controls senescence in plants.
Coenzyme Q10 protects against burn-induced mitochondrial dysfunction and impaired insulin signaling in mouse skeletal muscle.
Invertible promoters mediate bacterial phase variation, antibiotic resistance, and host adaptation in the gut
Core-Shell Modeling of Light Scattering by Vesicles: Effect of Size, Contents, and Lamellarity.
Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response.
Template-directed catalysis of a multi-step reaction pathway for nonenzymatic RNA primer extension.
Genomic variation and strain-specific functional adaptation in the human gut microbiome during early life.
Mitogen-activated protein kinases MPK3 and MPK6 are required for stem cell maintenance in the Arabidopsis shoot apical meristem.
Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis.
Gut microbiome structure and metabolic activity in inflammatory bowel disease.
Single-cell RNA Sequencing of Blood and Ileal T cells From Patients With Crohn's Disease Reveals Tissue-specific Characteristics and Drug Targets.
A non-canonical autophagy-dependent role of the ATG16L1T300A variant in urothelial vesicular trafficking and uropathogenic Escherichia coli persistence.
Platelet transfusion increases risk for acute respiratory distress syndrome in non-massively transfused blunt trauma patients.
