Publications for All Faculty
Inosine, but none of the 8-oxo-purines, is a plausible component of a primordial version of RNA.
CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data.
Gut microbiota composition and functional changes in inflammatory bowel disease and irritable bowel syndrome.
TOR and RPS6 transmit light signals to enhance protein translation in deetiolating Arabidopsis seedlings.
An ATG16L1-dependent pathway promotes plasma membrane repair and limits Listeria monocytogenes cell-to-cell spread.
T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation.
T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation.
Temporal development of the gut microbiome in early childhood from the TEDDY study.
The human gut microbiome in early-onset type 1 diabetes from the TEDDY study.
DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity.
Antigen discovery and specification of immunodominance hierarchies for MHCII-restricted epitopes.
Catalysis of Template-directed Nonenzymatic RNA Copying by Iron (II).
GPR108, an NF-κB activator suppressed by TIRAP, negatively regulates TLR-triggered immune responses.
Endoplasmic Reticulum Homeostasis Is Modulated by the Forkhead Transcription Factor FKH-9 During Infection of Caenorhabditis elegans.
Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course.
Discovery of heterocyclic replacements for the coumarin core of anti-tubercular FadD32 inhibitors.
In vivo CRISPR editing with no detectable genome-wide off-target mutations.
Tracing My Roots: How I Became a Plant Biologist.
Protocells and RNA Self-Replication.
Salt-Inducible Kinases: Physiology, Regulation by cAMP, and Therapeutic Potential.
Discovery and Optimization of nTZDpa as an Antibiotic Effective Against Bacterial Persisters.
Carbapenem resistance caused by high-level expression of OXA-663 β-lactamase in an OmpK36-deficient Klebsiella pneumoniae clinical isolate.
TMEM41B is a novel regulator of autophagy and lipid mobilization.
Harnessing CRISPR Effectors for Infectious Disease Diagnostics.
Acceleration profiles and processing methods for parabolic flight.
An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities.
Impaired Aryl Hydrocarbon Receptor Ligand Production by the Gut Microbiota Is a Key Factor in Metabolic Syndrome.
TOR signaling in plants: conservation and innovation.
Recent Molecular Genetic Explorations of Caenorhabditis elegans MicroRNAs.
Strain-Level Analysis of Mother-to-Child Bacterial Transmission during the First Few Months of Life.
Nitric Oxide Engages an Anti-inflammatory Feedback Loop Mediated by Peroxiredoxin 5 in Phagocytes.
The causes and consequences of variation in human cytokine production in health.
Crystallographic observation of nonenzymatic RNA primer extension.
Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population.
Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses.
Long-term effects of patiromer for hyperkalaemia treatment in patients with mild heart failure and diabetic nephropathy on angiotensin-converting enzymes/angiotensin receptor blockers: results from AMETHYST-DN.
Sequencing nothing: Exploring failure modes of nanopore sensing and implications for life detection.
The surveillance of pre-mRNA splicing is an early step in C. elegans RNAi of endogenous genes.
Genetic Markers Predict Primary Nonresponse and Durable Response to Anti-Tumor Necrosis Factor Therapy in Ulcerative Colitis.
Copying of mixed sequence RNA templates inside model protocells.
Without Adaptive Immunity, There's a Cost to Responding STAT.
Impact of Genetic Variation on CRISPR-Cas Targeting.
Response to "Unexpected mutations after CRISPR-Cas9 editing in vivo".
A new class of synthetic retinoid antibiotics effective against bacterial persisters.
A common mechanism links activities of butyrate in the colon.
CarrierSeq: a sequence analysis workflow for low-input nanopore sequencing.
Whole-organism phenotypic screening for anti-infectives promoting host health.
Metagenomic mining of regulatory elements enables programmable species-selective gene expression.
Quorum-sensing regulator RhlR but not its autoinducer RhlI enablesPseudomonasto evade opsonization.
Fatty Acid/Phospholipid Blended Membranes: A Potential Intermediate State in Protocellular Evolution.
Both live and dead Enterococci activate Caenorhabditis elegans host defense via immune and stress pathways.
Preparation, Purification, and Use of Fatty Acid-containing Liposomes.
The expanding diversity of Mycobacterium tuberculosis drug targets.
A structural rationale for the enhanced catalysis of nonenzymatic RNA primer extension by a downstream oligonucleotide.
C1orf106 is a colitis risk gene that regulates stability of epithelial adherens junctions.
Strain Tracking Reveals the Determinants of Bacterial Engraftment in the Human Gut Following Fecal Microbiota Transplantation.
Strain Tracking Reveals the Determinants of Bacterial Engraftment in the Human Gut Following Fecal Microbiota Transplantation.
Host genetic variation and its microbiome interactions within the Human Microbiome Project.
Loss of Response to Anti-Tumor Necrosis Factor Alpha Therapy in Crohn's Disease Is Not Associated with Emergence of Novel Inflammatory Pathways.
Influence of multiplicative stochastic variation on translational elongation rates.
Genomic and expression analyses identify a disease modifying variant for fibrostenotic Crohn's disease.
Solvated-electron production using cyanocuprates is compatible with the UV-environment on a Hadean-Archaean Earth.
Dynamics of metatranscription in the inflammatory bowel disease gut microbiome.
Gene therapy comes of age.
Synthesis of a nonhydrolyzable nucleotide phosphoroimidazolide analogue that catalyzes nonenzymatic RNA primer extension.
Difference in clinical course, genetics, and the microbiome between familial and sporadic inflammatory bowel diseases.
Development of Clinical Process Measures for Pediatric Burn Care: Understanding Variation in Practice Patterns.
Mechanisms and Function of Autophagy in Intestinal Disease.
Rhizosphere-associated Pseudomonas induce systemic resistance to herbivores at the cost of susceptibility to bacterial pathogens.
Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease.
