Publications for All Faculty
Quantifying Risk Factors for Long-Term Sleep Problems After Burn Injury in Young Adults.
Accelerating research through reagent repositories: the genome editing example.
Pinpointing RNA-protein crosslinks with site-specific stable isotope labeled oligonucleotides.
Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition.
LXR agonism up-regulates the macrophage ABCA1/syntrophin protein complex which can bind apoA-I and stabilized ABCA1 protein, but complex loss does not inhibit lipid efflux.
Bidirectional direct sequencing of non-canonical RNA by two-dimensional analysis of mass chromatograms.
Gene Expression of Proresolving Lipid Mediator Pathways Is Associated With Clinical Outcomes in Trauma Patients.
Novel links in the plant TOR kinase signaling network.
Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation.
Genome Editing in Human Cells Using CRISPR/Cas Nucleases.
Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation.
Antibacterial properties of 3-(phenylsulfonyl)-2-pyrazinecarbonitrile.
CAUSEL: an epigenome- and genome-editing pipeline for establishing function of noncoding GWAS variants.
Dialogue between E. coli free radical pathways and the mitochondria of C. elegans.
Patiromer induces rapid and sustained potassium lowering in patients with chronic kidney disease and hyperkalemia.
The Gut Microbiome Contributes to a Substantial Proportion of the Variation in Blood Lipids.
A Noncanonical Autophagy Pathway Restricts Toxoplasma gondii Growth in a Strain-Specific Manner in IFN-?-Activated Human Cells.
A Noncanonical Autophagy Pathway Restricts Toxoplasma gondii Growth in a Strain-Specific Manner in IFN-?-Activated Human Cells.
ConStrains identifies microbial strains in metagenomic datasets.
Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses.
Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses.
Lipid signalling couples translational surveillance to systemic detoxification in Caenorhabditis elegans.
HIV infection induces structural and functional changes in high density lipoproteins.
Enhancing immunity by engineering DAMPs.
Is Real-Time Feedback of Burn-Specific Patient-Reported Outcome Measures in Clinical Settings Practical and Useful? A Pilot Study Implementing the Young Adult Burn Outcome Questionnaire.
piRNAs and piRNA-Dependent siRNAs Protect Conserved and Essential C. elegans Genes from Misrouting into the RNAi Pathway.
Continuous directed evolution of DNA-binding proteins to improve TALEN specificity.
Thermodynamic insights into 2-thiouridine-enhanced RNA hybridization.
Common Genetic Variants Influence Circulating Vitamin D Levels in Inflammatory Bowel Diseases.
MICROBIOME. Plant microbiome blueprints.
Growth dynamics of gut microbiota in health and disease inferred from single metagenomic samples.
Electrostatic Localization of RNA to Protocell Membranes by Cationic Hydrophobic Peptides.
Functional genomics identifies negative regulatory nodes controlling phagocyte oxidative burst.
Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics.
Body Mass Index, Genetic Susceptibility, and Risk of Complications Among Individuals with Crohn's Disease.
Role of Autophagy in the Maintenance of Intestinal Homeostasis.
Unwanted mutations: Standards needed for gene-editing errors.
Effect of Patiromer on Serum Potassium Level in Patients With Hyperkalemia and Diabetic Kidney Disease: The AMETHYST-DN Randomized Clinical Trial.
Stimulation of Liver X Receptor Has Potent Anti-HIV Effects in a Humanized Mouse Model.
Engineered CRISPR-Cas9 nucleases with altered PAM specificities.
Integrated Genomics of Crohn's Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy.
Dimeric CRISPR RNA-guided FokI-dCas9 nucleases (RFNs) directed by truncated gRNAs for highly specific genome editing.
A Defensin from the Model Beetle Tribolium castaneum Acts Synergistically with Telavancin and Daptomycin against Multidrug Resistant Staphylococcus aureus.
Identification of an Antimicrobial Agent Effective against Methicillin-Resistant Staphylococcus aureus Persisters Using a Fluorescence-Based Screening Strategy.
CARMA3 Is Critical for the Initiation of Allergic Airway Inflammation.
Construction of a liposome dialyzer for the preparation of high-value, small-volume liposome formulations.
Rescue of DNA-PK Signaling and T-Cell Differentiation by Targeted Genome Editing in a prkdc Deficient iPSC Disease Model.
The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells.
Targeted Mutagenesis in Zebrafish Using CRISPR RNA-Guided Nucleases.
Natural bacterial communities serve as quantitative geochemical biosensors.
Associations with rhizosphere bacteria can confer an adaptive advantage to plants.
Associations with rhizosphere bacteria can confer an adaptive advantage to plants.
PhyloGene server for identification and visualization of co-evolving proteins using normalized phylogenetic profiles.
Genome editing technologies: defining a path to clinic.
An Integrative View of Microbiome-Host Interactions in Inflammatory Bowel Diseases.
Hypoxia drives transient site-specific copy gain and drug-resistant gene expression.
Jasmonate signalling in Arabidopsis involves SGT1b-HSP70-HSP90 chaperone complexes.
Do standard burn mortality formulae work on a population of severely burned children and adults?
Uncovering the Thermodynamics of Monomer Binding for RNA Replication.
Repurposing Salicylanilide Anthelmintic Drugs to Combat Drug Resistant Staphylococcus aureus.
Direct detection and drug-resistance profiling of bacteremias using inertial microfluidics.
Future Translational Applications From the Contemporary Genomics Era: A Scientific Statement From the American Heart Association.
Plant immunity triggered by engineered in vivo release of oligogalacturonides, damage-associated molecular patterns.
Discovery of a Small-Molecule Probe for V-ATPase Function.
Associations between host gene expression, the mucosal microbiome, and clinical outcome in the pelvic pouch of patients with inflammatory bowel disease.
Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells.
Targeted Plant Genome Editing via the CRISPR/Cas9 Technology.
Genomics of injury: The Glue Grant experience.
Simultaneous generation of many RNA-seq libraries in a single reaction.
Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature.
Pathogen-secreted proteases activate a novel plant immune pathway.
A novel role for KLF14 in T regulatory cell differentiation.
Chromatin regulation at the frontier of synthetic biology.
Replacing Uridine with 2-Thio-Uridine Enhances the Rate and Fidelity of Nonenzymatic RNA Primer Extension.
The Dynamics of the Human Infant Gut Microbiome in Development and in Progression toward Type 1 Diabetes.
Intake of farmed Atlantic salmon fed soybean oil increases hepatic levels of arachidonic acid-derived oxylipins and ceramides in mice.
A new antibiotic with potent activity targets MscL.
Exome Sequencing in Suspected Monogenic Dyslipidemias.
Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa.
Disease-Specific Alterations in the Enteric Virome in Inflammatory Bowel Disease.
Role of Protein Farnesylation in Burn-Induced Metabolic Derangements and Insulin Resistance in Mouse Skeletal Muscle.
Insect-derived Cecropins Display Activity Against Acinetobacter baumannii in a Whole-Animal High-Throughput Caenorhabditis elegans Model.
Pyruvate Kinase M2 Regulates Hif-1? Activity and IL-1? Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages.
Morbidity and Survival Probability in Burn Patients in Modern Burn Care.
Fanconi Anemia Gene Editing by the CRISPR/Cas9 System.
Mice are not men.
Generation of functional RNAs from inactive oligonucleotide complexes by non-enzymatic primer extension.
GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases.
A Zebrafish Model of Myelodysplastic Syndrome Produced Through tet2 Genomic Editing.
Autophagy and checkpoints for intracellular pathogen defense.
Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo.
Apoplastic peroxidases are required for salicylic acid-mediated defense against Pseudomonas syringae.
Simvastatin Reduces Burn Injury-Induced Splenic Apoptosis via Downregulation of the TNF-?/NF-?B Pathway.
Prediction of Multiple Infections After Severe Burn Trauma: A Prospective Cohort Study.
Survival From Burns in the New Millennium: 70 Years' Experience From a Single Institution.
