Publications for All Faculty
Concentration-driven growth of model protocell membranes.
The LRR and RING Domain Protein LRSAM1 Is an E3 Ligase Crucial for Ubiquitin-Dependent Autophagy of Intracellular Salmonella Typhimurium.
Cell Host Microbe. 2012;12(6):778-90 - PMID: 23245322 - PMCID: PMC3785244 - DOI: 10.1016/j.chom.2012.10.019
Reply to Guy et al.: Support for a bottleneck in the 2011 Escherichia coli O104:H4 outbreak in Germany.
Proc Natl Acad Sci U S A. 2012;109(52):E3629-30 - PMID: 23479789 - PMCID: PMC3535640 - DOI: 10.1073/pnas.1209419110
Concentration-driven growth of model protocell membranes.
Stem Cell Signaling in Immunity and Development.
Cold Spring Harb Symp Quant Biol. 2012;77:75-81 - PMID: 23174766 - DOI: 10.1101/sqb.2012.77.014837
Measurement of Phagocytosis, Phagosome Acidification, and Intracellular Killing of Staphylococcus aureus.
Curr Protoc Immunol. 2012;Chapter 14:14.30.1-14.30.12 - PMID: 23129153 - DOI: 10.1002/0471142735.im1430s99
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
Combination of Radiation and Burn Injury Alters [18F] 2-Fluoro-2-Deoxy-D-Glucose Uptake in Mice.
J Burn Care Res. 2012;33(6):723-30 - PMID: 23143615 - PMCID: PMC3673011 - DOI: 10.1097/BCR.0b013e31825d678f
A High-content Imaging Workflow to Study Grb2 Signaling Complexes by Expression Cloning.
A high-content imaging workflow to study Grb2 signaling complexes by expression cloning.
Prediction of C. elegans Longevity Genes by Human and Worm Longevity Networks.
PLoS One. 2012;7(10):e48282 - PMID: 23144747 - PMCID: PMC3483217 - DOI: 10.1371/journal.pone.0048282
Common alleles that influence autophagy and the risk for inflammatory bowel disease.
Curr Opin Immunol. 2012;24(5):522-9 - PMID: 23041451 - DOI: 10.1016/j.coi.2012.08.001
Engineering Designer Transcription Activator--Like Effector Nucleases (TALENs) by REAL or REAL-Fast Assembly.
Curr Protoc Mol Biol. 2012;Chapter 12:Unit12.15 - PMID: 23026907 - PMCID: PMC3753116 - DOI: 10.1002/0471142727.mb1215s100
Imaging C-Fos Gene Expression in Burns Using Lipid Coated Spion Nanoparticles.
Adv J Mol Imaging. 2012;2(4):31-37 - PMID: 24995147 - PMCID: PMC4076698 - DOI: 10.4236/ami.2012.24005
The Two-Component Sensor KinB Acts as a Phosphatase to Regulate Pseudomonas aeruginosa Virulence.
Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment.
Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes.
Proc Natl Acad Sci U S A. 2012;109(43):17537-42 - PMID: 22988082 - PMCID: PMC3491454 - DOI: 10.1073/pnas.1202870109
Essential cell autonomous role for interferon regulatory factor 1 in interferon-?-mediated inhibition of norovirus replication in macrophages.
Evaluation of OPEN Zinc Finger Nucleases for Direct Gene Targeting of the ROSA26 Locus in Mouse Embryos.
Measuring the cost of care for children with acute burn injury.
J Trauma Acute Care Surg. 2012;73(3 Suppl 2):S229-33 - PMID: 22929551 - DOI: 10.1097/TA.0b013e318265c88a
Impact of hand burns on health-related quality of life in children younger than 5 years.
J Trauma Acute Care Surg. 2012;73(3 Suppl 2):S197-204 - PMID: 22929547 - DOI: 10.1097/TA.0b013e318265c7ff
The American Burn Association/Shriners Hospitals for Children Burn Outcomes Program: A progress report at 15 years.
J Trauma Acute Care Surg. 2012;73(3 Suppl 2):S173-8 - PMID: 22929544 - DOI: 10.1097/TA.0b013e318265c53e
Previous burn injury predisposes mice to lipopolysaccharide-induced changes in glucose metabolism.
J Burn Care Res. 2012;33(5):683-9 - PMID: 22961012 - PMCID: PMC3441057 - DOI: 10.1097/BCR.0b013e31825d6a86
Safety and dosing of bevacizumab (avastin) for the treatment of recurrent respiratory papillomatosis.
Ann Otol Rhinol Laryngol. 2012;121(9):587-93 - PMID: 23012897 - DOI: 10.1177/000348941212100905
Complexity in Differential Peptide-Receptor Signaling: Response to Segonzac et al. and Mueller et al. Commentaries.
FLS2-Mediated Responses to Ax21-Derived Peptides: Response to the Mueller et al. Commentary.
p40phox Expression Regulates Neutrophil Recruitment and Function during the Resolution Phase of Intestinal Inflammation.
Multicomponent assembly of proposed DNA precursors in water.
Enhanced Tim3 Activity Improves Survival after Influenza Infection.
Enhanced Tim3 activity improves survival after influenza infection.
New insights into siRNA amplification and RNAi.
A synthetic biology framework for programming eukaryotic transcription functions.
Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes.
Cell Host Microbe. 2012;12(2):223-32 - PMID: 22901542 - PMCID: PMC3864037 - DOI: 10.1016/j.chom.2012.06.006
Multicomponent assembly of proposed DNA precursors in water.
Gram-Negative Bacterial Infection in Thigh Abscess Can Migrate to Distant Burn Depending on Burn Depth.
Interdiscip Perspect Infect Dis. 2012;2012:567140 - PMID: 22899912 - PMCID: PMC3412104 - DOI: 10.1155/2012/567140
Genome-Wide Identification of Pseudomonas aeruginosa Virulence-Related Genes Using a Caenorhabditis elegans Infection Model.
PLoS Pathog. 2012;8(7):e1002813 - PMID: 22911607 - PMCID: PMC3406104 - DOI: 10.1371/journal.ppat.1002813
Genes Involved in the Evolution of Herbivory By A Leaf-Mining, Drosophilid Fly.
TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria.
Induction of cytoprotective pathways is central to the extension of lifespan conferred by multiple longevity pathways.
PLoS Genet. 2012;8(7):e1002792 - PMID: 22829775 - PMCID: PMC3400582 - DOI: 10.1371/journal.pgen.1002792
Eradication of bacterial persisters with antibiotic-generated hydroxyl radicals.
Proc Natl Acad Sci U S A. 2012;109(30):12147-52 - PMID: 22778419 - PMCID: PMC3409745 - DOI: 10.1073/pnas.1203735109
EGL-9 Controls C. elegans Host Defense Specificity through Prolyl Hydroxylation-Dependent and -Independent HIF-1 Pathways.
PLoS Pathog. 2012;8(7):e1002798 - PMID: 22792069 - PMCID: PMC3390412 - DOI: 10.1371/journal.ppat.1002798
Perception of volatiles produced by UVC-irradiated plants alters the response to viral infection in naïve neighboring plants.
Case 23-2012.
N Engl J Med. 2012;367(4):363-73 - PMID: 22830467 - DOI: 10.1056/NEJMcpc1109275
Non-invasive mapping of the gastrointestinal microbiota identifies children with inflammatory bowel disease.
Non-invasive mapping of the gastrointestinal microbiota identifies children with inflammatory bowel disease.
Helminth Infection Impairs Autophagy-Mediated Killing of Bacterial Enteropathogens by Macrophages.
MUT-16 promotes formation of perinuclear Mutator foci required for RNA silencing in the C. elegans germline.
Stimulation of Host Immune Defenses by a Small Molecule Protects C. elegans from Bacterial Infection.
PLoS Genet. 2012;8(6):e1002733 - PMID: 22719261 - PMCID: PMC3375230 - DOI: 10.1371/journal.pgen.1002733
A framework for human microbiome research.
Structure, function and diversity of the healthy human microbiome.
Highly efficient generation of heritable zebrafish gene mutations using homo- and heterodimeric TALENs.
Nucleic Acids Res. 2012;40(16):8001-10 - PMID: 22684503 - PMCID: PMC3439908 - DOI: 10.1093/nar/gks518
Photochemically driven redox chemistry induces protocell membrane pearling and division.
Proc Natl Acad Sci U S A. 2012;109(25):9828-32 - PMID: 22665773 - PMCID: PMC3382484 - DOI: 10.1073/pnas.1203212109
Cytokinin signaling networks
Annu Rev Plant Biology. . 2012;63:353-380
An interview with Jen Sheen.
Trends Plant Sci. 2012;17(6):321-2 - PMID: 22860262 - DOI: 10.1016/j.tplants.2012.03.006
Clinical review. Comparative effectiveness of drug treatments to prevent fragility fractures: a systematic review and network meta-analysis.
J Clin Endocrinol Metab. 2012;97(6):1871-80 - PMID: 22466336 - DOI: 10.1210/jc.2011-3060
Improved Somatic Mutagenesis in Zebrafish Using Transcription Activator-Like Effector Nucleases (TALENs).
Transient expression assays for quantifying signaling output.
Methods Mol Biol. 2012;876:195-206 - PMID: 22576097 - DOI: 10.1007/978-1-61779-809-2_16
Identification of novel inhibitors of M. tuberculosis growth using whole cell based high-throughput screening.
Penetration Resistance: PKR's Other Talent.
Immunity. 2012;36(5):695-6 - PMID: 22633454 - DOI: 10.1016/j.immuni.2012.05.010
In vitro selection of functional lantipeptides.
In vivo molecular imaging of murine embryonic stem cells delivered to a burn wound surface via Integra® scaffolding.
J Burn Care Res. 2012;33(2):e49-54 - PMID: 22540138 - PMCID: PMC3311992 - DOI: 10.1097/BCR.0b013e3182331d1c
The Caenorhabditis elegans RDE-10/RDE-11 Complex Regulates RNAi by Promoting Secondary siRNA Amplification.
An image analysis toolbox for high-throughput C. elegans assays.
PIWI Associated siRNAs and piRNAs Specifically Require the Caenorhabditis elegans HEN1 Ortholog henn-1.
PLoS Genet. 2012;8(4):e1002616 - PMID: 22536158 - PMCID: PMC3334881 - DOI: 10.1371/journal.pgen.1002616
Establishment and characterization of a novel chordoma cell line: CH22.
J Orthop Res. 2012;30(10):1666-73 - PMID: 22504929 - DOI: 10.1002/jor.22113
FLASH assembly of TALENs for high-throughput genome editing.
Regulation of monocyte functional heterogeneity by miR-146a and Relb.
Cell Rep. 2012;1(4):317-324 - PMID: 22545247 - PMCID: PMC3334310 - DOI: 10.1016/j.celrep.2012.02.009
RNA signatures allow rapid identification of pathogens and antibiotic susceptibilities.
Proc Natl Acad Sci U S A. 2012;109(16):6217-22 - PMID: 22474362 - PMCID: PMC3341018 - DOI: 10.1073/pnas.1119540109
Patterns of Care at End of Life in Children With Advanced Heart Disease.
Arch Pediatr Adolesc Med. 2012;166(8):745-8 - PMID: 22473887 - PMCID: PMC4119813 - DOI: 10.1001/archpediatrics.2011.1829
Autophagy and the immune system.
Annu Rev Immunol. 2012;30:611-46 - PMID: 22449030 - DOI: 10.1146/annurev-immunol-020711-074948
The changing pattern and implications of multiple organ failure after blunt injury with hemorrhagic shock*
Crit Care Med. 2012;40(4):1129-1135 - PMID: 22020243 - PMCID: PMC3343366 - DOI: 10.1097/CCM.0b013e3182376e9f
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses.
Host Translational Inhibition by Pseudomonas aeruginosa Exotoxin A Triggers an Immune Response in Caenorhabditis elegans.
Cell Host Microbe. 2012;11(4):364-74 - PMID: 22520464 - PMCID: PMC3334877 - DOI: 10.1016/j.chom.2012.02.007
Nondegradative Role of Atg5-Atg12/ Atg16L1 Autophagy Protein Complex in Antiviral Activity of Interferon Gamma.
Cell Host Microbe. 2012;11(4):397-409 - PMID: 22520467 - PMCID: PMC3348177 - DOI: 10.1016/j.chom.2012.03.002
Guidelines for the use and interpretation of assays for monitoring autophagy.
Benchmarking Outcomes in the Critically Injured Trauma Patient and the Effect of Implementing Standard Operating Procedures.
Ann Surg. 2012;255(5):993-9 - PMID: 22470077 - PMCID: PMC3327791 - DOI: 10.1097/SLA.0b013e31824f1ebc
Targeted parallel sequencing of large genetically-defined genomic regions for identifying mutations in Arabidopsis.
Clinical review. Risk factors for low bone mass-related fractures in men: a systematic review and meta-analysis.
J Clin Endocrinol Metab. 2012;97(6):1861-70 - PMID: 22466344 - DOI: 10.1210/jc.2011-3058
In Vitro Selection of Highly Modified Cyclic Peptides That Act as Tight Binding Inhibitors.
Apoptotic cells can deliver chemotherapeutics to engulfing macrophages and suppress inflammatory cytokine production.
J Biol Chem. 2012;287(19):16029-36 - PMID: 22433861 - PMCID: PMC3346138 - DOI: 10.1074/jbc.M112.340489
Integration of architectural and cytologic driven image algorithms for prostate adenocarcinoma identification.
Anal Cell Pathol (Amst). 2012;35(4):251-65 - PMID: 22425661 - PMCID: PMC4605585 - DOI: 10.3233/ACP-2012-0054
DNA purification from multiple sources in plant research with homemade silica resins.
Methods Mol Biol. 2012;862:53-9 - PMID: 22419488 - DOI: 10.1007/978-1-61779-609-8_5
Repression of Germline RNAi Pathways in Somatic Cells by Retinoblastoma Pathway Chromatin Complexes.
PLoS Genet. 2012;8(3):e1002542 - PMID: 22412383 - PMCID: PMC3297578 - DOI: 10.1371/journal.pgen.1002542
The mevalonate pathway regulates microRNA activity in Caenorhabditis elegans.
Proc Natl Acad Sci U S A. 2012;109(12):4568-73 - PMID: 22396595 - PMCID: PMC3311396 - DOI: 10.1073/pnas.1202421109
In Vivo Molecular Imaging of Murine Embryonic Stem Cells Delivered to a Burn Wound Surface via Integra® Scaffolding.
J Burn Care Res. 2012;33(2):e49-54 - PMID: 22441149 - PMCID: PMC3311992
ONCOGENIC KRAS REGULATES BMP4 EXPRESSION IN COLON CANCER CELL LINES.
Am J Physiol Gastrointest Liver Physiol. 2012;302(10):G1223-30 - PMID: 22383492 - PMCID: PMC3362092 - DOI: 10.1152/ajpgi.00047.2011
Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects.
Nucleic Acids Res. 2012;40(12):5560-8 - PMID: 22373919 - PMCID: PMC3384306 - DOI: 10.1093/nar/gks179
A Peroxidase-Dependent Apoplastic Oxidative Burst in Cultured Arabidopsis Cells Functions in MAMP-Elicited Defense.
Plant Physiol. 2012;158(4):2013-27 - PMID: 22319074 - PMCID: PMC3320203 - DOI: 10.1104/pp.111.190140
Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011.
Proc Natl Acad Sci U S A. 2012;109(8):3065-70 - PMID: 22315421 - PMCID: PMC3286951 - DOI: 10.1073/pnas.1121491109
Activated ribonucleotides undergo a sugar pucker switch upon binding to a single-stranded RNA template.
Severe injury is associated with insulin resistance, endoplasmic reticulum stress response, and unfolded protein response.
Ann Surg. 2012;255(2):370-8 - PMID: 22241293 - PMCID: PMC3395076 - DOI: 10.1097/SLA.0b013e31823e76e7
Attempts to define life do not help to understand the origin of life.
J Biomol Struct Dyn. 2012;29(4):599-600 - PMID: 22208251 - PMCID: PMC4208307 - DOI: 10.1080/073911012010524998
Survival of children with burn injuries.
Lancet. 2012;379(9820):983-4 - PMID: 22296811 - PMCID: PMC4019221 - DOI: 10.1016/S0140-6736(11)61626-7
Thermal Injury Activates eEF2k-Dependent eEF2 Pathway in Pediatric Patients.
JPEN J Parenter Enteral Nutr. 2012;36(5):596-602 - PMID: 22269896 - PMCID: PMC3580832 - DOI: 10.1177/0148607111422234
Tribbles 2 (Trib2) is a novel regulator of toll-like receptor 5 signaling.
HIV-1 Nef mobilizes lipid rafts in macrophages through a pathway that competes with ABCA1-dependent cholesterol efflux.
Genome-wide siRNA screen for mediators of NF-?B activation.
Proc Natl Acad Sci U S A. 2012;109(7):2467-72 - PMID: 22308454 - PMCID: PMC3289371 - DOI: 10.1073/pnas.1120542109
The apoplastic oxidative burst peroxidase in Arabidopsis is a major component of pattern-triggered immunity.
Immune defense mechanisms in the Caenorhabditis elegans intestinal epithelium.
Curr Opin Immunol. 2012;24(1):3-9 - PMID: 22236697 - PMCID: PMC3660727 - DOI: 10.1016/j.coi.2011.10.004
The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques.
Incidence of Catheter-Associated Bloodstream Infection After Introduction of Minocycline and Rifampin Antimicrobial-Coated Catheters in a Pediatric Burn Population.
J Burn Care Res. 2012;33(4):539-43 - PMID: 22210071 - DOI: 10.1097/BCR.0b013e31823c4cd5
STAT6 phosphorylation inhibitors block eotaxin-3 secretion in bronchial epithelial cells.
Bioorg Med Chem. 2012;20(2):750-8 - PMID: 22217933 - DOI: 10.1016/j.bmc.2011.12.006
SILAM for quantitative proteomics of liver Akt1/PKB? after burn injury.
Autophagy suppresses interleukin-1? (IL-1?) signaling by activation of p62 degradation via lysosomal and proteasomal pathways.
J Biol Chem. 2012;287(6):4033-40 - PMID: 22167182 - PMCID: PMC3281713 - DOI: 10.1074/jbc.M111.280065
Resuscitation-promoting factors are required for ?-lactam tolerance and the permeability barrier in Mycobacterium tuberculosis.
Antimicrob Agents Chemother. 2012;56(3):1591-4 - PMID: 22155826 - PMCID: PMC3294900 - DOI: 10.1128/AAC.06027-11
Rapamycin and glucose-target of rapamycin (TOR) protein signaling in plants.
J Biol Chem. 2012;287(4):2836-42 - PMID: 22134914 - PMCID: PMC3268441 - DOI: 10.1074/jbc.M111.300749
The Creating an Optimal Warfarin Nomogram (CROWN) Study.
Systematics-guided bioprospecting for bioactive microbial natural products.
Antonie Van Leeuwenhoek. 2012;101(1):55-66 - PMID: 22086462 - DOI: 10.1007/s10482-011-9671-1
PrimerBank: a PCR primer database for quantitative gene expression analysis, 2012 update.
Nucleic Acids Res. 2012;40(Database issue):D1144-9 - PMID: 22086960 - PMCID: PMC3245149 - DOI: 10.1093/nar/gkr1013
Down-regulation of glutatione S-transferase ? 4 (hGSTA4) in the muscle of thermally injured patients is indicative of susceptibility to bacterial infection.
Genome-wide expression profiling implicates a MAST3-regulated gene set in colonic mucosal inflammation of ulcerative colitis patients.
Control of NOD2 and Rip2-dependent innate immune activation by GEF-H1.
Total: 112


