Publications for All Faculty
Lipoprotein Metabolism and the Treatment of Lipid Disorders, Chapter 42. In: DeGroot LJ and JL Jameson, eds
Control and manipulation of pathogens with an optical trap for live cell imaging of intercellular interactions.
Cancer. Germ cell genes and cancer.
Failure and exploitation of autophagy in human pathologies-cellular integrity between inflammation, infection, and cell survival.
The contribution of muscle to whole-body protein turnover throughout the course of burn injury in children.
av Integrin expression by DCs is required for Th17 cell differentiation and development of experimental autoimmune encephalomyelitis in mice.
Stem cells and burns: review and therapeutic implications.
Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences.
Chemoselective multicomponent one-pot assembly of purine precursors in water.
Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection.
LRRK2 is involved in the IFN-gamma response and host response to pathogens.
DNA ends: just the beginning (Nobel lecture).
Discover and connect cellular signaling.
Morphology-guided graph search for untangling objects: C. elegans analysis.
Mutation of the ATP cassette binding transporter A1 (ABCA1) C-terminus disrupts HIV-1 Nef binding but does not block the Nef enhancement of ABCA1 protein degradation.
Plasma proteome response to severe burn injury revealed by 18O-labeled "universal" reference-based quantitative proteomics.
Effect of simvastatin on burn-induced alterations in tissue specific glucose metabolism: implications for burn associated insulin resistance.
Mobility of plasmids.
Clinical microfluidics for neutrophil genomics and proteomics.
Human IRGM gene "to be or not to be".
Autonomous zinc-finger nuclease pairs for targeted chromosomal deletion.
Engineering single Cys2His2 zinc finger domains using a bacterial cell-based two-hybrid selection system.
Single-molecule binding experiments on long time scales.
Circulating Nef induces dyslipidemia in simian immunodeficiency virus-infected macaques by suppressing cholesterol efflux.
Burn injury reduces neutrophil directional migration speed in microfluidic devices.
Reactive bone marrow stromal cells attenuate systemic inflammation via sTNFR1.
Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease.
Wnt signaling regulates mitochondrial physiology and insulin sensitivity.
Distinct pathogenesis and host responses during infection of C. elegans by P. aeruginosa and S. aureus.
A systems biology viewpoint on autophagy in health and disease.
The transcription factor MafB antagonizes antiviral responses by blocking recruitment of coactivators to the transcription factor IRF3.
Bone marrow mesenchymal stromal cells attenuate organ injury induced by LPS and burn.
Mice lacking Dok-1, Dok-2, and Dok-3 succumb to aggressive histiocytic sarcoma.
Mesenchymal stem cells: Mechanisms of immunomodulation and homing.
Conformationally constrained spiro C-arylglucosides as potent and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors.
A genome-wide siRNA screen reveals multiple mTORC1 independent signaling pathways regulating autophagy under normal nutritional conditions.
Characterization and analysis of human chordoma cell lines.
Expanding roles for diverse physical phenomena during the origin of life.
Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine.
Differential expression of microRNA (miRNA) in chordoma reveals a role for miRNA-1 in Met expression.
RESOLVING CLUSTERED WORMS VIA PROBABILISTIC SHAPE MODELS.
Activating WASP mutations associated with X-linked neutropenia result in enhanced actin polymerization, altered cytoskeletal responses, and genomic instability in lymphocytes.
High frequency targeted mutagenesis in Arabidopsis thaliana using zinc finger nucleases.
Berberine-INF55 (5-nitro-2-phenylindole) hybrid antimicrobials: effects of varying the relative orientation of the berberine and INF55 components.
Helical apolipoproteins of high-density lipoprotein enhance phagocytosis by stabilizing ATP-binding cassette transporter A7.
The origins of cellular life.
Phagocytosis and phagosome acidification are required for pathogen processing and MyD88-dependent responses to Staphylococcus aureus.
MiR-33 contributes to the regulation of cholesterol homeostasis.
ZiFiT (Zinc Finger Targeter): an updated zinc finger engineering tool.
ortho-Substituted C-aryl glucosides as highly potent and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors.
Host-encoded reporters for the detection and purification of multiple enveloped viruses.
Gene enrichment profiles reveal T-cell development, differentiation, and lineage-specific transcription factors including ZBTB25 as a novel NF-AT repressor.
Identification of Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated muramyl dipeptide transporters.
99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: Caenorhabditis elegans as a model to study tissues involved in host immunity and microbial pathogenesis.
Effect of stalling after mismatches on the error catastrophe in nonenzymatic nucleic acid replication.
Innate immune responses activated in Arabidopsis roots by microbe-associated molecular patterns.
Binding of PDZ-RhoGEF to ATP-binding cassette transporter A1 (ABCA1) induces cholesterol efflux through RhoA activation and prevention of transporter degradation.
MLT-10 defines a family of DUF644 and proline-rich repeat proteins involved in the molting cycle of Caenorhabditis elegans.
Exploring the interplay of barrier function and leukocyte recruitment in intestinal inflammation by targeting fucosyltransferase VII and trefoil factor 3.
Genome-wide association identifies multiple ulcerative colitis susceptibility loci.
Isolation and characterization of circulating tumor cells from patients with localized and metastatic prostate cancer.
Differential innate immune signalling via Ca(2+) sensor protein kinases.
Analysis of high-throughput sequencing and annotation strategies for phage genomes.
The fast track to multidrug resistance.
ABC transporters, atherosclerosis and inflammation.
bZIP transcription factor zip-2 mediates an early response to Pseudomonas aeruginosa infection in Caenorhabditis elegans.
Protocol: a rapid and economical procedure for purification of plasmid or plant DNA with diverse applications in plant biology.
Early acute kidney injury predicts progressive renal dysfunction and higher mortality in severely burned adults.
Fluorosomes: a convenient new reagent to detect and block multivalent and complex receptor-ligand interactions.
Evolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebrates.
Autophagy at the gut interface: mucosal responses to stress and the consequences for inflammatory bowel diseases.
CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer.
Low glucose uncouples hexokinase1-dependent sugar signaling from stress and defense hormone abscisic acid and C2H4 responses in Arabidopsis.
PrimerBank: a resource of human and mouse PCR primer pairs for gene expression detection and quantification.
Short-term signatures of evolutionary change in the Salmonella enterica serovar typhimurium 14028 genome.
Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly.
