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Foley JE, Maeder ML, Pearlberg J, Joung JK, Peterson RT, Yeh JR

Targeted mutagenesis in zebrafish using customized zinc-finger nucleases.
Nat Protoc. 2009;4(12):1855-67 - PMID: 20010934 - PMCID: PMC2814337 - DOI: 10.1038/nprot.2009.209

Sebastiani P, Montano M, Puca A, Solovieff N, Kojima T, Wang MC, Melista E, Meltzer M, Fischer SE, Andersen S, Hartley SH, Sedgewick A, Arai Y, Bergman A, Barzilai N, Terry DF, Riva A, Anselmi CV, Malovini A, Kitamoto A, Sawabe M, Arai T, Gondo Y, Steinberg MH, Hirose N, Atzmon G, Ruvkun G, Baldwin CT, Perls TT

RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans.
PLoS One. 2009;4(12):e8210 - PMID: 20011587 - PMCID: PMC2788130 - DOI: 10.1371/journal.pone.0008210

Hett EC, Hung DT

Targeting multiple biofilm pathways.
Chem Biol. 2009;16(12):1216-8 - PMID: 20064430 - DOI: 10.1016/j.chembiol.2009.12.003

Brass AL, Huang IC, Benita Y, John SP, Krishnan MN, Feeley EM, Ryan BJ, Weyer JL, van der Weyden L, Fikrig E, Adams DJ, Xavier RJ, Farzan M, Elledge SJ

The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus.
Cell. 2009;139(7):1243-54 - PMID: 20064371 - PMCID: PMC2824905 - DOI: 10.1016/j.cell.2009.12.017

Voytas DF, Joung JK

Plant science. DNA binding made easy.
Science. 2009;326(5959):1491-2 - PMID: 20007890 - PMCID: PMC7814878 - DOI: 10.1126/science.1183604

Bruckner RJ, Mansy SS, Ricardo A, Mahadevan L, Szostak JW

Flip-flop-induced relaxation of bending energy: implications for membrane remodeling.
Biophys J. 2009;97(12):3113-22 - PMID: 20006948 - PMCID: PMC2793357 - DOI: 10.1016/j.bpj.2009.09.025

Stanley SA, Hung DT

Toward a systems-level analysis of infection biology: a new method for conducting genetic screens in human cells.
Sci Transl Med. 2009;1(11):11ps13 - PMID: 20371455 - DOI: 10.1126/scitranslmed.3000550

Fujii H, Chinnusamy V, Rodrigues A, Rubio S, Antoni R, Park SY, Cutler SR, Sheen J, Rodriguez PL, Zhu JK

In vitro reconstitution of an abscisic acid signalling pathway.
Nature. 2009;462(7273):660-4 - PMID: 19924127 - PMCID: PMC2803041 - DOI: 10.1038/nature08599

Imielinski M, Baldassano RN, Griffiths A, Russell RK, Annese V, Dubinsky M, Kugathasan S, Bradfield JP, Walters TD, Sleiman P, Kim CE, Muise A, Wang K, Glessner JT, Saeed S, Zhang H, Frackelton EC, Hou C, Flory JH, Otieno G, Chiavacci RM, Grundmeier R, Castro M, Latiano A, Dallapiccola B, Stempak J, Abrams DJ, Taylor K, McGovern D, , Silber G, Wrobel I, Quiros A, , Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmuda MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO, Murtha MT, Regueiro MD, Rotter JI, Schumm LP, Steinhart AH, Targan SR, Xavier RJ, , Libioulle C, Sandor C, Lathrop M, Belaiche J, Dewit O, Gut I, Heath S, Laukens D, Mni M, Rutgeerts P, Van Gossum A, Zelenika D, Franchimont D, Hugot JP, de Vos M, Vermeire S, Louis E, , , Cardon LR, Anderson CA, Drummond H, Nimmo E, Ahmad T, Prescott NJ, Onnie CM, Fisher SA, Marchini J, Ghori J, Bumpstead S, Gwillam R, Tremelling M, Delukas P, Mansfield J, Jewell D, Satsangi J, Mathew CG, Parkes M, Georges M, Daly MJ, Heyman MB, Ferry GD, Kirschner B, Lee J, Essers J, Grand R, Stephens M, Levine A, Piccoli D, Van Limbergen J, Cucchiara S, Monos DS, Guthery SL, Denson L, Wilson DC, Grant SF, Daly M, Silverberg MS, Satsangi J, Hakonarson H

Common variants at five new loci associated with early-onset inflammatory bowel disease.
Nat Genet. 2009;41(12):1335-40 - PMID: 19915574 - PMCID: PMC3267927 - DOI: 10.1038/ng.489

O'Rourke EJ, Soukas AA, Carr CE, Ruvkun G

C. elegans major fats are stored in vesicles distinct from lysosome-related organelles.
Cell Metab. 2009;10(5):430-5 - PMID: 19883620 - PMCID: PMC2921818 - DOI: 10.1016/j.cmet.2009.10.002

Yagi H, Parekkadan B, Suganuma K, Soto-Gutierrez A, Tompkins RG, Tilles AW, Yarmush ML

Long-term superior performance of a stem cell/hepatocyte device for the treatment of acute liver failure.
Tissue Eng Part A. 2009;15(11):3377-88 - PMID: 19397469 - PMCID: PMC2792056 - DOI: 10.1089/ten.TEA.2008.0681

Heath RJ, Xavier RJ

Autophagy, immunity and human disease.
Curr Opin Gastroenterol. 2009;25(6):512-20 - PMID: 19826372 - PMCID: PMC2849745 - DOI: 10.1097/MOG.0b013e32833104f1

Lv B, Xu B, Feng Y, Peng K, Xu G, Du J, Zhang L, Zhang W, Zhang T, Zhu L, Ding H, Sheng Z, Welihinda A, Seed B, Chen Y

Exploration of O-spiroketal C-arylglucosides as novel and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors.
Bioorg Med Chem Lett. 2009;19(24):6877-81 - PMID: 19896374 - DOI: 10.1016/j.bmcl.2009.10.088

Lu XM, Hamrahi VF, Tompkins RG, Fischman AJ

Effect of insulin levels on the phosphorylation of specific amino acid residues in IRS-1: implications for burn-induced insulin resistance.
Int J Mol Med. 2009;24(4):531-8 - PMID: 19724894 - PMCID: PMC4084762 - DOI: 10.3892/ijmm_00000262

Stoddard FJ, Sorrentino EA, Ceranoglu TA, Saxe G, Murphy JM, Drake JE, Ronfeldt H, White GW, Kagan J, Snidman N, Sheridan RL, Tompkins RG

Preliminary evidence for the effects of morphine on posttraumatic stress disorder symptoms in one- to four-year-olds with burns.
J Burn Care Res. 2009;30(5):836-43 - PMID: 19692914 - DOI: 10.1097/BCR.0b013e3181b48102

Cobb JP, Moore EE, Hayden DL, Minei JP, Cuschieri J, Yang J, Li Q, Lin N, Brownstein BH, Hennessy L, Mason PH, Schierding WS, Dixon DJ, Tompkins RG, Warren HS, Schoenfeld DA, Maier RV

Validation of the riboleukogram to detect ventilator-associated pneumonia after severe injury.
Ann Surg. 2009;250(4):531-9 - PMID: 19730236 - PMCID: PMC3047595 - DOI: 10.1097/SLA.0b013e3181b8fbd5

Maslowski KM, Vieira AT, Ng A, Kranich J, Sierro F, Yu D, Schilter HC, Rolph MS, Mackay F, Artis D, Xavier RJ, Teixeira MM, Mackay CR

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43.
Nature. 2009;461(7268):1282-6 - PMID: 19865172 - PMCID: PMC3256734 - DOI: 10.1038/nature08530

Schrum JP, Ricardo A, Krishnamurthy M, Blain JC, Szostak JW

Efficient and rapid template-directed nucleic acid copying using 2'-amino-2',3'-dideoxyribonucleoside-5'-phosphorimidazolide monomers.
J Am Chem Soc. 2009;131(40):14560-70 - PMID: 19757789 - PMCID: PMC2759813 - DOI: 10.1021/ja906557v

Maeder ML, Thibodeau-Beganny S, Sander JD, Voytas DF, Joung JK

Oligomerized pool engineering (OPEN): an 'open-source' protocol for making customized zinc-finger arrays.
Nat Protoc. 2009;4(10):1471-501 - PMID: 19798082 - PMCID: PMC2858690 - DOI: 10.1038/nprot.2009.98

Okoli I, Coleman JJ, Tampakakis E, Tempakakis E, An WF, Holson E, Wagner F, Conery AL, Larkins-Ford J, Wu G, Stern A, Ausubel FM, Mylonakis E

Identification of antifungal compounds active against Candida albicans using an improved high-throughput Caenorhabditis elegans assay.
PLoS One. 2009;4(9):e7025 - PMID: 19750012 - PMCID: PMC2737148 - DOI: 10.1371/journal.pone.0007025

Mansy SS, Szostak JW

Reconstructing the emergence of cellular life through the synthesis of model protocells.
Cold Spring Harb Symp Quant Biol. 2009;74:47-54 - PMID: 19734203 - DOI: 10.1101/sqb.2009.74.014

Ricardo A, Szostak JW

Origin of life on earth.
Sci Am. 2009;301(3):54-61 - PMID: 19708528 - DOI: 10.1038/scientificamerican0909-54

Lin S, Horning DP, Szostak JW, Chaput JC

Conformational analysis of DNA repair intermediates by time-resolved fluorescence spectroscopy.
J Phys Chem A. 2009;113(35):9585-7 - PMID: 19673467 - PMCID: PMC2733762 - DOI: 10.1021/jp906746w

Stanley SA, Hung DT

Chemical tools for dissecting bacterial physiology and virulence.
Biochemistry. 2009;48(37):8776-86 - PMID: 19653697 - DOI: 10.1021/bi9009083

Tzika AA, Mintzopoulos D, Mindrinos M, Zhang J, Rahme LG, Tompkins RG

Microarray analysis suggests that burn injury results in mitochondrial dysfunction in human skeletal muscle.
Int J Mol Med. 2009;24(3):387-92 - PMID: 19639232 - PMCID: PMC3207251 - DOI: 10.3892/ijmm_00000244

Haydock GS and MW Freeman

Screening for hyperlipidemia. In: Goroll A and Mulley A, eds.
Primary Care Medicine, 6th Edition. 2009;:ePub

M Freeman, Consultant editor, 4th edition. Buckley, Rita

What to do about high cholesterol
President and Fellows of Harvard College. Harvard Health Publications. 2009;:ePub

MW Freeman

Approach to the patient with hypercholesterolemia. In: Goroll A, May L, Mulley A, eds
Primary Care Medicine, 6th Edition. 2009;:ePub

Li Q, Brass AL, Ng A, Hu Z, Xavier RJ, Liang TJ, Elledge SJ

A genome-wide genetic screen for host factors required for hepatitis C virus propagation.
Proc Natl Acad Sci U S A. 2009;106(38):16410-5 - PMID: 19717417 - PMCID: PMC2752535 - DOI: 10.1073/pnas.0907439106

Huett A, Xavier R

Building complex biological networks based upon model organisms: mapping the human autophagy interactome via a hybrid yeast-human protein interaction network.
Autophagy. 2009;5(6):884-6 - PMID: 19535904 - DOI: 10.4161/auto.9094

Xu B, Lv B, Feng Y, Xu G, Du J, Welihinda A, Sheng Z, Seed B, Chen Y

O-Spiro C-aryl glucosides as novel sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors.
Bioorg Med Chem Lett. 2009;19(19):5632-5 - PMID: 19700318 - DOI: 10.1016/j.bmcl.2009.08.030

Barczak AK, Hung DT

Productive steps toward an antimicrobial targeting virulence.
Curr Opin Microbiol. 2009;12(5):490-6 - PMID: 19631578 - PMCID: PMC2763366 - DOI: 10.1016/j.mib.2009.06.012

Tamehiro N, Mujawar Z, Zhou S, Zhuang DZ, Hornemann T, von Eckardstein A, Fitzgerald ML

Cell polarity factor Par3 binds SPTLC1 and modulates monocyte serine palmitoyltransferase activity and chemotaxis.
J Biol Chem. 2009;284(37):24881-90 - PMID: 19592499 - PMCID: PMC2757191 - DOI: 10.1074/jbc.M109.014365

Stephenson LM, Miller BC, Ng A, Eisenberg J, Zhao Z, Cadwell K, Graham DB, Mizushima NN, Xavier R, Virgin HW, Swat W

Identification of Atg5-dependent transcriptional changes and increases in mitochondrial mass in Atg5-deficient T lymphocytes.
Autophagy. 2009;5(5):625-35 - PMID: 19276668 - PMCID: PMC3737142 - DOI: 10.4161/auto.5.5.8133

Budin I, Bruckner RJ, Szostak JW

Formation of protocell-like vesicles in a thermal diffusion column.
J Am Chem Soc. 2009;131(28):9628-9 - PMID: 19601679 - PMCID: PMC2710859 - DOI: 10.1021/ja9029818

Moy TI, Conery AL, Larkins-Ford J, Wu G, Mazitschek R, Casadei G, Lewis K, Carpenter AE, Ausubel FM

High-throughput screen for novel antimicrobials using a whole animal infection model.
ACS Chem Biol. 2009;4(7):527-33 - PMID: 19572548 - PMCID: PMC2745594 - DOI: 10.1021/cb900084v

Elenko MP, Szostak JW, van Oijen AM

Single-molecule imaging of an in vitro-evolved RNA aptamer reveals homogeneous ligand binding kinetics.
J Am Chem Soc. 2009;131(29):9866-7 - PMID: 19572753 - PMCID: PMC2716146 - DOI: 10.1021/ja901880v

Ip WK, Takahashi K, Ezekowitz RA, Stuart LM

Mannose-binding lectin and innate immunity.
Immunol Rev. 2009;230(1):9-21 - PMID: 19594626 - DOI: 10.1111/j.1600-065X.2009.00789.x

Raychaudhuri S, Plenge RM, Rossin EJ, Ng AC, , Purcell SM, Sklar P, Scolnick EM, Xavier RJ, Altshuler D, Daly MJ

Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions.
PLoS Genet. 2009;5(6):e1000534 - PMID: 19557189 - PMCID: PMC2694358 - DOI: 10.1371/journal.pgen.1000534

Zou J, Maeder ML, Mali P, Pruett-Miller SM, Thibodeau-Beganny S, Chou BK, Chen G, Ye Z, Park IH, Daley GQ, Porteus MH, Joung JK, Cheng L

Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells.
Cell Stem Cell. 2009;5(1):97-110 - PMID: 19540188 - PMCID: PMC2720132 - DOI: 10.1016/j.stem.2009.05.023

Curran SP, Wu X, Riedel CG, Ruvkun G

A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants.
Nature. 2009;459(7250):1079-84 - PMID: 19506556 - PMCID: PMC2716045 - DOI: 10.1038/nature08106

Leb VM, Jahn-Schmid B, Kueng HJ, Schmetterer KG, Haiderer D, Neunkirchner A, Fischer GF, Hartl A, Thalhamer J, Steinberger P, Bohle B, Seed B, Pickl WF

Modulation of allergen-specific T-lymphocyte function by virus-like particles decorated with HLA class II molecules.
J Allergy Clin Immunol. 2009;124(1):121-8 - PMID: 19500826 - DOI: 10.1016/j.jaci.2009.04.008

Benita Y, Kikuchi H, Smith AD, Zhang MQ, Chung DC, Xavier RJ

An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia.
Nucleic Acids Res. 2009;37(14):4587-602 - PMID: 19491311 - PMCID: PMC2724271 - DOI: 10.1093/nar/gkp425

Szostak JW

Origins of life: Systems chemistry on early Earth.
Nature. 2009;459(7244):171-2 - PMID: 19444196 - DOI: 10.1038/459171a

Luong MX, Tam J, Lin Q, Hagendoorn J, Moore KJ, Padera TP, Seed B, Fukumura D, Kucherlapati R, Jain RK

Lack of lymphatic vessel phenotype in LYVE-1/CD44 double knockout mice.
J Cell Physiol. 2009;219(2):430-7 - PMID: 19170073 - PMCID: PMC2665001 - DOI: 10.1002/jcp.21686

Townsend JA, Wright DA, Winfrey RJ, Fu F, Maeder ML, Joung JK, Voytas DF

High-frequency modification of plant genes using engineered zinc-finger nucleases.
Nature. 2009;459(7245):442-5 - PMID: 19404258 - PMCID: PMC2743854 - DOI: 10.1038/nature07845

Litovchick A, Szostak JW

Retraction for Litovchick and Szostak. "Selection of cyclic peptide aptamers to HCV IRES RNA using mRNA display".
Proc Natl Acad Sci U S A. 2009;106(17):7263 - PMID: 19380733 - PMCID: PMC2678432 - DOI: 10.1073/pnas.0903110106

Yoo SD, Cho Y, Sheen J

Emerging connections in the ethylene signaling network.
Trends Plant Sci. 2009;14(5):270-9 - PMID: 19375376 - PMCID: PMC3063992 - DOI: 10.1016/j.tplants.2009.02.007

Huett A, Leong JM, Podolsky DK, Xavier RJ

The cytoskeletal scaffold Shank3 is recruited to pathogen-induced actin rearrangements.
Exp Cell Res. 2009;315(12):2001-11 - PMID: 19371741 - PMCID: PMC2693461 - DOI: 10.1016/j.yexcr.2009.04.003

Warren HS, Elson CM, Hayden DL, Schoenfeld DA, Cobb JP, Maier RV, Moldawer LL, Moore EE, Harbrecht BG, Pelak K, Cuschieri J, Herndon DN, Jeschke MG, Finnerty CC, Brownstein BH, Hennessy L, Mason PH, Tompkins RG,

A genomic score prognostic of outcome in trauma patients.
Mol Med. 2009;15(7-8):220-7 - PMID: 19593405 - PMCID: PMC2707513 - DOI: 10.2119/molmed.2009.00027

Tran C, Ouk S, Clegg NJ, Chen Y, Watson PA, Arora V, Wongvipat J, Smith-Jones PM, Yoo D, Kwon A, Wasielewska T, Welsbie D, Chen CD, Higano CS, Beer TM, Hung DT, Scher HI, Jung ME, Sawyers CL

Development of a second-generation antiandrogen for treatment of advanced prostate cancer.
Science. 2009;324(5928):787-90 - PMID: 19359544 - PMCID: PMC2981508 - DOI: 10.1126/science.1168175

Zhu TF, Szostak JW

Preparation of large monodisperse vesicles.
PLoS One. 2009;4(4):e5009 - PMID: 19347043 - PMCID: PMC2661144 - DOI: 10.1371/journal.pone.0005009

Yin HN, Chai JK, Yu YM, Shen CA, Wu YQ, Yao YM, Liu H, Liang LM, Tompkins RG, Sheng ZY

Regulation of signaling pathways downstream of IGF-I/insulin by androgen in skeletal muscle of glucocorticoid-treated rats.
J Trauma. 2009;66(4):1083-90 - PMID: 19359918 - PMCID: PMC4085982 - DOI: 10.1097/TA.0b013e31817e7420

Urbach JM, Wei T, Liberati N, Grenfell-Lee D, Villanueva J, Wu G, Ausubel FM

Using PATIMDB to create bacterial transposon insertion mutant libraries.
Curr Protoc Mol Biol. 2009;Chapter 19:Unit 19.7 - PMID: 19343706 - PMCID: PMC4492697 - DOI: 10.1002/0471142727.mb1907s86

Huett A, Ng A, Cao Z, Kuballa P, Komatsu M, Daly MJ, Podolsky DK, Xavier RJ

A novel hybrid yeast-human network analysis reveals an essential role for FNBP1L in antibacterial autophagy.
J Immunol. 2009;182(8):4917-30 - PMID: 19342671 - PMCID: PMC2752416 - DOI: 10.4049/jimmunol.0803050

Zhu TF, Szostak JW

Coupled growth and division of model protocell membranes.
J Am Chem Soc. 2009;131(15):5705-13 - PMID: 19323552 - PMCID: PMC2669828 - DOI: 10.1021/ja900919c

Chen JJ, Tsai CH, Cai X, Horhota AT, McLaughlin LW, Szostak JW

Enzymatic primer-extension with glycerol-nucleoside triphosphates on DNA templates.
PLoS One. 2009;4(3):e4949 - PMID: 19305495 - PMCID: PMC2654545 - DOI: 10.1371/journal.pone.0004949

Adams JC, Seed B, Lu N, Landry A, Xavier RJ

Selective activation of nuclear factor kappa B in the cochlea by sensory and inflammatory stress.
Neuroscience. 2009;160(2):530-9 - PMID: 19285117 - PMCID: PMC2673023 - DOI: 10.1016/j.neuroscience.2009.02.073

Adams JC, Seed B, Lu N, Landry A, Xavier RJ

Selective activation of nuclear factor kappa B in the cochlea by sensory and inflammatory stress.
Neuroscience. 2009;160(2):530-9 - PMID: 19285117 - PMCID: PMC2673023 - DOI: 10.1016/j.neuroscience.2009.02.073

Tai AW, Benita Y, Peng LF, Kim SS, Sakamoto N, Xavier RJ, Chung RT

A functional genomic screen identifies cellular cofactors of hepatitis C virus replication.
Cell Host Microbe. 2009;5(3):298-307 - PMID: 19286138 - PMCID: PMC2756022 - DOI: 10.1016/j.chom.2009.02.001

Foley JE, Yeh JR, Maeder ML, Reyon D, Sander JD, Peterson RT, Joung JK

Rapid mutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool ENgineering (OPEN).
PLoS One. 2009;4(2):e4348 - PMID: 19198653 - PMCID: PMC2634973 - DOI: 10.1371/journal.pone.0004348

Festen EA, Goyette P, Scott R, Annese V, Zhernakova A, Lian J, Lefèbvre C, Brant SR, Cho JH, Silverberg MS, Taylor KD, de Jong DJ, Stokkers PC, Mcgovern D, Palmieri O, Achkar JP, Xavier RJ, Daly MJ, Duerr RH, Wijmenga C, Weersma RK, Rioux JD

Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis.
Gut. 2009;58(6):799-804 - PMID: 19201773 - PMCID: PMC2757103 - DOI: 10.1136/gut.2008.166918

Powell JR, Kim DH, Ausubel FM

The G protein-coupled receptor FSHR-1 is required for the Caenorhabditis elegans innate immune response.
Proc Natl Acad Sci U S A. 2009;106(8):2782-7 - PMID: 19196974 - PMCID: PMC2650343 - DOI: 10.1073/pnas.0813048106

Cheng X, Gupta A, Chen C, Tompkins RG, Rodriguez W, Toner M

Enhancing the performance of a point-of-care CD4+ T-cell counting microchip through monocyte depletion for HIV/AIDS diagnostics.
Lab Chip. 2009;9(10):1357-64 - PMID: 19417901 - PMCID: PMC4064257 - DOI: 10.1039/b818813k

Imamura T, Kikuchi H, Herraiz MT, Park DY, Mizukami Y, Mino-Kenduson M, Lynch MP, Rueda BR, Benita Y, Xavier RJ, Chung DC

HIF-1alpha and HIF-2alpha have divergent roles in colon cancer.
Int J Cancer. 2009;124(4):763-71 - PMID: 19030186 - PMCID: PMC2682346 - DOI: 10.1002/ijc.24032

Chen JJ, Cai X, Szostak JW

N2'-->p3' phosphoramidate glycerol nucleic acid as a potential alternative genetic system.
J Am Chem Soc. 2009;131(6):2119-21 - PMID: 19166350 - PMCID: PMC2722806 - DOI: 10.1021/ja809069b

Soukas AA, Kane EA, Carr CE, Melo JA, Ruvkun G

Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans.
Genes Dev. 2009;23(4):496-511 - PMID: 19240135 - PMCID: PMC2648650 - DOI: 10.1101/gad.1775409

Chandran D, Tai YC, Hather G, Dewdney J, Denoux C, Burgess DG, Ausubel FM, Speed TP, Wildermuth MC

Temporal global expression data reveal known and novel salicylate-impacted processes and regulators mediating powdery mildew growth and reproduction on Arabidopsis.
Plant Physiol. 2009;149(3):1435-51 - PMID: 19176722 - PMCID: PMC2649394 - DOI: 10.1104/pp.108.132985

Butcher RA, Ragains JR, Li W, Ruvkun G, Clardy J, Mak HY

Biosynthesis of the Caenorhabditis elegans dauer pheromone.
Proc Natl Acad Sci U S A. 2009;106(6):1875-9 - PMID: 19174521 - PMCID: PMC2631283 - DOI: 10.1073/pnas.0810338106

Huett A, McCarroll SA, Daly MJ, Xavier RJ

On the level: IRGM gene function is all about expression.
Autophagy. 2009;5(1):96-9 - PMID: 19029815 - PMCID: PMC3204672 - DOI: 10.4161/auto.5.1.7263

Clatworthy AE, Lee JS, Leibman M, Kostun Z, Davidson AJ, Hung DT

Pseudomonas aeruginosa infection of zebrafish involves both host and pathogen determinants.
Infect Immun. 2009;77(4):1293-303 - PMID: 19168742 - PMCID: PMC2663173 - DOI: 10.1128/IAI.01181-08

Neely AN, Gardner J, Durkee P, Warden GD, Greenhalgh DG, Gallagher JJ, Herndon DN, Tompkins RG, Kagan RJ

Are topical antimicrobials effective against bacteria that are highly resistant to systemic antibiotics?
J Burn Care Res. 2009;30(1):19-29 - PMID: 19060725 - DOI: 10.1097/BCR.0b013e3181921eed

Medoff BD, Sandall BP, Landry A, Nagahama K, Mizoguchi A, Luster AD, Xavier RJ

Differential requirement for CARMA1 in agonist-selected T-cell development.
Eur J Immunol. 2009;39(1):78-84 - PMID: 19130560 - PMCID: PMC2747028 - DOI: 10.1002/eji.200838734

Qian WJ, Liu T, Petyuk VA, Gritsenko MA, Petritis BO, Polpitiya AD, Kaushal A, Xiao W, Finnerty CC, Jeschke MG, Jaitly N, Monroe ME, Moore RJ, Moldawer LL, Davis RW, Tompkins RG, Herndon DN, Camp DG, Smith RD,

Large-scale multiplexed quantitative discovery proteomics enabled by the use of an (18)O-labeled "universal" reference sample.
J Proteome Res. 2009;8(1):290-9 - PMID: 19053531 - PMCID: PMC2752204 - DOI: 10.1021/pr800467r

Clay NK, Adio AM, Denoux C, Jander G, Ausubel FM

Glucosinolate metabolites required for an Arabidopsis innate immune response.
Science. 2009;323(5910):95-101 - PMID: 19095898 - PMCID: PMC2630859 - DOI: 10.1126/science.1164627

Avruch J, Xavier R, Bardeesy N, Zhang XF, Praskova M, Zhou D, Xia F

Rassf family of tumor suppressor polypeptides.
J Biol Chem. 2009;284(17):11001-5 - PMID: 19091744 - PMCID: PMC2670104 - DOI: 10.1074/jbc.R800073200

Nusbaum C, Ohsumi TK, Gomez J, Aquadro J, Victor TC, Warren RM, Hung DT, Birren BW, Lander ES, Jaffe DB

Sensitive, specific polymorphism discovery in bacteria using massively parallel sequencing.
Nat Methods. 2009;6(1):67-9 - PMID: 19079253 - PMCID: PMC2613166 - DOI: 10.1038/nmeth.1286

Sander JD, Zaback P, Joung JK, Voytas DF, Dobbs D

An affinity-based scoring scheme for predicting DNA-binding activities of modularly assembled zinc-finger proteins.
Nucleic Acids Res. 2009;37(2):506-15 - PMID: 19056825 - PMCID: PMC2632909 - DOI: 10.1093/nar/gkn962

Irimia D, Mindrinos M, Russom A, Xiao W, Wilhelmy J, Wang S, Heath JD, Kurn N, Tompkins RG, Davis RW, Toner M

Genome-wide transcriptome analysis of 150 cell samples.
Integr Biol (Camb). 2009;1(1):99-107 - PMID: 20023796 - PMCID: PMC3763906 - DOI: 10.1039/b814329c

Guttormsen HK, Stuart LM, Shi L, Carroll MC, Chen J, Kasper DL, Ezekowitz RA, Takahashi K

Deficiency of mannose-binding lectin greatly increases antibody response in a mouse model of vaccination.
Clin Immunol. 2009;130(3):264-71 - PMID: 18996748 - PMCID: PMC2660855 - DOI: 10.1016/j.clim.2008.09.012

Manning-Tobin JJ, Moore KJ, Seimon TA, Bell SA, Sharuk M, Alvarez-Leite JI, de Winther MP, Tabas I, Freeman MW

Loss of SR-A and CD36 activity reduces atherosclerotic lesion complexity without abrogating foam cell formation in hyperlipidemic mice.
Arterioscler Thromb Vasc Biol. 2009;29(1):19-26 - PMID: 18948635 - PMCID: PMC2666043 - DOI: 10.1161/ATVBAHA.108.176644

Fu F, Sander JD, Maeder M, Thibodeau-Beganny S, Joung JK, Dobbs D, Miller L, Voytas DF

Zinc Finger Database (ZiFDB): a repository for information on C2H2 zinc fingers and engineered zinc-finger arrays.
Nucleic Acids Res. 2009;37(Database issue):D279-83 - PMID: 18812396 - PMCID: PMC2686427 - DOI: 10.1093/nar/gkn606

Medoff BD, Landry AL, Wittbold KA, Sandall BP, Derby MC, Cao Z, Adams JC, Xavier RJ

CARMA3 mediates lysophosphatidic acid-stimulated cytokine secretion by bronchial epithelial cells.
Am J Respir Cell Mol Biol. 2009;40(3):286-94 - PMID: 18757306 - PMCID: PMC2645526 - DOI: 10.1165/rcmb.2008-0129OC
Total: 83