Publications for All Faculty
A comprehensive collection of experimentally validated primers for Polymerase Chain Reaction quantitation of murine transcript abundance.
Genome-wide SNP genotyping highlights the role of natural selection in Plasmodium falciparum population divergence.
The Nore1B/Mst1 complex restrains antigen receptor-induced proliferation of naïve T cells.
A metasystem of framework model organisms to study emergence of new host-microbe adaptations.
Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway.
Microsporidia are natural intracellular parasites of the nematode Caenorhabditis elegans.
Impact of oxandrolone treatment on acute outcomes after severe burn injury.
Role for beta-catenin and HOX transcription factors in Caenorhabditis elegans and mammalian host epithelial-pathogen interactions.
Fat metabolism links germline stem cells and longevity in C. elegans.
ABCA12 maintains the epidermal lipid permeability barrier by facilitating formation of ceramide linoleic esters.
Sugar sensing and signaling.
The most conserved genome segments for life detection on Earth and other planets.
Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant.
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells.
The perfect storm of tiny RNAs.
A microfluidics approach for the isolation of nucleated red blood cells (NRBCs) from the peripheral blood of pregnant women.
Selection of cyclic peptide aptamers to HCV IRES RNA using mRNA display.
Temporal cytokine profiles in severely burned patients: a comparison of adults and children.
The AtrbohD-mediated oxidative burst elicited by oligogalacturonides in Arabidopsis is dispensable for the activation of defense responses effective against Botrytis cinerea.
Myelinated, synapsing cultures of murine spinal cord--validation as an in vitro model of the central nervous system.
Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7.
Thermostability of model protocell membranes.
Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease.
Targeting innate immunity for CV benefit
RNA interference screen for human genes associated with West Nile virus infection.
Convergent energy and stress signaling.
Genome-wide association studies: a new window into immune-mediated diseases.
Genome-wide association studies: a new window into immune-mediated diseases.
MAST3: a novel IBD risk factor that modulates TLR4 signaling.
Hoxc6 is overexpressed in gastrointestinal carcinoids and interacts with JunD to regulate tumor growth.
Molecular association between beta-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/beta-catenin signaling.
The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response.
Detection of mutations in EGFR in circulating lung-cancer cells.
Attenuation of Pseudomonas aeruginosa virulence by medicinal plants in a Caenorhabditis elegans model system.
Bacterial effectors target the common signaling partner BAK1 to disrupt multiple MAMP receptor-signaling complexes and impede plant immunity.
Rapid open-source engineering of customized zinc-finger nucleases for highly efficient gene modification.
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.
Early supplemental parenteral nutrition is associated with increased infectious complications in critically ill trauma patients.
Tiny RNA: Where do we come from? What are we? Where are we going?
Zinc-finger nucleases: the next generation emerges.
Animal models for host-pathogen interactions.
Template-directed synthesis of a genetic polymer in a model protocell.
Identification of Caenorhabditis elegans genes regulating longevity using enhanced RNAi-sensitive strains.
Quantitation of autophagy by luciferase release assay.
Murine intramyocellular lipids quantified by NMR act as metabolic biomarkers in burn trauma.
cDNA sequences for transcription factors and signaling proteins of the hemichordate Saccoglossus kowalevskii: efficacy of the expressed sequence tag (EST) approach for evolutionary and developmental studies of a new organism.
Activation of defense response pathways by OGs and Flg22 elicitors in Arabidopsis seedlings.
Genetic identification of HSD-1, a conserved steroidogenic enzyme that directs larval development in Caenorhabditis elegans.
SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter.
Neither hide nor hair: the difficulty of identifying useful disease biomarkers.
Expression and evolutionary features of the hexokinase gene family in Arabidopsis.
Cytokinin and auxin interaction in root stem-cell specification during early embryogenesis.
The microRNA miR-1 regulates a MEF-2-dependent retrograde signal at neuromuscular junctions.
Unexpected failure rates for modular assembly of engineered zinc fingers.
Estimating glutathione synthesis with deuterated water: a model for peptide biosynthesis.
The exonuclease ERI-1 has a conserved dual role in 5.8S rRNA processing and RNAi.
Spinophilin and the immune synapse.
Ribosomal synthesis of N-methyl peptides.
Comparing insertion libraries in two Pseudomonas aeruginosa strains to assess gene essentiality.
Increased uncoupling protein 1 mRNA expression in mice brown adipose tissue after burn injury.
Burn-related metabolic and signaling changes in rat brain.
A pathway sensor for genome-wide screens of intracellular proteolytic cleavage.
Microfluidic leukocyte isolation for gene expression analysis in critically ill hospitalized patients.
Models of Caenorhabditis elegans infection by bacterial and fungal pathogens.
A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein.
Comparison of zinc finger nucleases for use in gene targeting in mammalian cells.
Engineering Cys2His2 zinc finger domains using a bacterial cell-based two-hybrid selection system.
Defining molecular classifications and targets in gastroenteropancreatic neuroendocrine tumors through DNA microarray analysis.
Improvement of bone disease by imiglucerase (Cerezyme) therapy in patients with skeletal manifestations of type 1 Gaucher disease: results of a 48-month longitudinal cohort study.
Equilibrium separation and filtration of particles using differential inertial focusing.
Autophagy as an important process in gut homeostasis and Crohn's disease pathogenesis.
Metal-ion catalyzed polymerization in the eutectic phase in water-ice: a possible approach to template-directed RNA polymerization.
DAF-16-dependent suppression of immunity during reproduction in Caenorhabditis elegans.
Invention, innovation, entrepreneurship in academic medical centers.
Phagocytosis and comparative innate immunity: learning on the fly.
Reduced rate of adenosine triphosphate synthesis by in vivo 31P nuclear magnetic resonance spectroscopy and downregulation of PGC-1beta in distal skeletal muscle following burn.
IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis.
Dual control of nuclear EIN3 by bifurcate MAPK cascades in C2H4 signalling.
Influence of age on the association of retinol-binding protein 4 with metabolic syndrome.
Gene-centric association mapping of chromosome 3p implicates MST1 in IBD pathogenesis.
Defective signal transduction in B lymphocytes lacking presenilin proteins.
Identification of host proteins required for HIV infection through a functional genomic screen.
MicroRNA-183 family conservation and ciliated neurosensory organ expression.
Mannose-binding lectin enhances Toll-like receptors 2 and 6 signaling from the phagosome.
SNPping away at the pathogenesis of Crohn's disease.
Miniprimer PCR, a new lens for viewing the microbial world.
Molecular and functional analysis of the antigen receptor of Art v 1-specific helper T lymphocytes.
DNA-binding specificity is a major determinant of the activity and toxicity of zinc-finger nucleases.
DLG1 is an anchor for the E3 ligase MARCH2 at sites of cell-cell contact.
