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Xu W, Rush JS, Graham DB, Cao Z, Xavier RJ

USP15 Deubiquitinates CARD9 to Downregulate C-Type Lectin Receptor-Mediated Signaling.
Immunohorizons. 2020;4(10):670-678 - PMID: 33093067 - PMCID: PMC7758836 - DOI: 10.4049/immunohorizons.2000036

Strom KR, Szostak JW

Solid-Phase Synthesis of Sequence-Defined Informational Oligomers.
J Org Chem. 2020;85(21):13929-13938 - PMID: 33064001 - PMCID: PMC9594334 - DOI: 10.1021/acs.joc.0c01977

Lee K, Escobar I, Jang Y, Kim W, Ausubel FM, Mylonakis E

In the Model Host Caenorhabditis elegans, Sphingosine-1-Phosphate-Mediated Signaling Increases Immunity toward Human Opportunistic Bacteria.
Int J Mol Sci. 2020;21(21):ePub - PMID: 33105563 - PMCID: PMC7672543 - DOI: 10.3390/ijms21217813

Carr CE, Bryan NC, Saboda KN, Bhattaru SA, Ruvkun G, Zuber MT

Nanopore sequencing at Mars, Europa, and microgravity conditions.
NPJ Microgravity. 2020;6(1):24 - PMID: 34489469 - DOI: 10.1038/s41526-020-00113-9

O'Flaherty DK, Zhou L, Szostak JW

Nonenzymatic RNA-templated Synthesis of N3'→P5' Phosphoramidate DNA.
Bio Protoc. 2020;10(17):e3734 - PMID: 33659395 - PMCID: PMC7842504 - DOI: 10.21769/BioProtoc.3734

Borren NZ, Plichta D, Joshi AD, Bonilla G, Sadreyev R, Vlamakis H, Xavier RJ, Ananthakrishnan AN

Multi-"-Omics" Profiling in Patients With Quiescent Inflammatory Bowel Disease Identifies Biomarkers Predicting Relapse.
Inflamm Bowel Dis. 2020;26(10):1524-1532 - PMID: 32766830 - PMCID: PMC7500522 - DOI: 10.1093/ibd/izaa183

Zhang SJ, Duzdevich D, Szostak JW

Potentially Prebiotic Activation Chemistry Compatible with Nonenzymatic RNA Copying.
J Am Chem Soc. 2020;142(35):14810-14813 - PMID: 32794700 - PMCID: PMC9594304 - DOI: 10.1021/jacs.0c05300

Zhou L, O'Flaherty DK, Szostak JW

Assembly of a ribozyme ligase from short oligomers by nonenzymatic ligation.
J Am Chem Soc. 2020;142(37):15961-15965 - PMID: 32820909 - PMCID: PMC9594310 - DOI: 10.1021/jacs.0c06722

Kong L, Lloyd-Price J, Vatanen T, Seksik P, Beaugerie L, Simon T, Vlamakis H, Sokol H, Xavier RJ

Linking strain engraftment in fecal microbiota transplantation with maintenance of remission in Crohn's disease.
Gastroenterology. 2020;159(6):2193-2202.e5 - PMID: 32860788 - PMCID: PMC7725862 - DOI: 10.1053/j.gastro.2020.08.045

Drokhlyansky E, Smillie CS, Van Wittenberghe N, Ericsson M, Griffin GK, Eraslan G, Dionne D, Cuoco MS, Goder-Reiser MN, Sharova T, Kuksenko O, Aguirre AJ, Boland GM, Graham D, Rozenblatt-Rosen O, Xavier RJ, Regev A

The Human and Mouse Enteric Nervous System at Single-Cell Resolution.
Cell. 2020;182(6):1606-1622.e23 - PMID: 32888429 - PMCID: PMC8358727 - DOI: 10.1016/j.cell.2020.08.003

Clement K, Hsu JY, Canver MC, Joung JK, Pinello L

Technologies and Computational Analysis Strategies for CRISPR Applications.
Mol Cell. 2020;79(1):11-29 - PMID: 32619467 - PMCID: PMC7497852 - DOI: 10.1016/j.molcel.2020.06.012

Kurt IC, Zhou R, Iyer S, Garcia SP, Miller BR, Langner LM, Grünewald J, Joung JK

CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells.
Nat Biotechnol. 2021;39(1):41-46 - PMID: 32690971 - PMCID: PMC7854778 - DOI: 10.1038/s41587-020-0609-x

Hu S, Vich Vila A, Gacesa R, Collij V, Stevens C, Fu JM, Wong I, Talkowski ME, Rivas MA, Imhann F, Bolte L, van Dullemen H, Dijkstra G, Visschedijk MC, Festen EA, Xavier RJ, Fu J, Daly MJ, Wijmenga C, Zhernakova A, Kurilshikov A, Weersma RK

Whole exome sequencing analyses reveal gene-microbiota interactions in the context of IBD.
Gut. 2021;70(2):285-296 - PMID: 32651235 - PMCID: PMC7815889 - DOI: 10.1136/gutjnl-2019-319706

Xavier RJ

Growth and the Microbiome - Integrating Global Health with Basic Science.
N Engl J Med. 2020;383(4):391-393 - PMID: 32706538 - DOI: 10.1056/NEJMe2017496

Virgin HW, Cuervo AM, Xavier RJ

Beth Cindy Levine (1960-2020).
Science. 2020;369(6502):378 - PMID: 32703867 - DOI: 10.1126/science.abd6216

Wei W, Ruvkun G

Lysosomal activity regulates Caenorhabditis elegans mitochondrial dynamics through vitamin B12 metabolism.
Proc Natl Acad Sci U S A. 2020;117(33):19970-19981 - PMID: 32737159 - PMCID: PMC7443905 - DOI: 10.1073/pnas.2008021117

Khader R, Tharmalingam N, Mishra B, Felix L, Ausubel FM, Kelso MJ, Mylonakis E

Characterization of Five Novel Anti-MRSA Compounds Identified Using a Whole-Animal Caenorhabditis elegans/Galleria mellonella Sequential-Screening Approach.
Antibiotics (Basel). 2020;9(8):ePub - PMID: 32726955 - PMCID: PMC7459823 - DOI: 10.3390/antibiotics9080449

Gomes ALC, Johns NI, Yang A, Velez-Cortes F, Smillie CS, Smith MB, Alm EJ, Wang HH

Genome and sequence determinants governing the expression of horizontally acquired DNA in bacteria.
ISME J. 2020;14(9):2347-2357 - PMID: 32514119 - PMCID: PMC7608860 - DOI: 10.1038/s41396-020-0696-1

Strecker J, Ladha A, Makarova KS, Koonin EV, Zhang F

Response to Comment on "RNA-guided DNA insertion with CRISPR-associated transposases".
Science. 2020;368(6495):ePub - PMID: 32499411 - DOI: 10.1126/science.abb2920

Grünewald J, Zhou R, Lareau CA, Garcia SP, Iyer S, Miller BR, Langner LM, Hsu JY, Aryee MJ, Joung JK

A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing.
Nat Biotechnol. 2020;38(7):861-864 - PMID: 32483364 - PMCID: PMC7723518 - DOI: 10.1038/s41587-020-0535-y

Zhou L, O'Flaherty DK, Szostak JW

Template-directed copying of RNA by non-enzymatic ligation.
Angew Chem Int Ed Engl. 2020;59(36):15682-15687 - PMID: 32558121 - PMCID: PMC7496532 - DOI: 10.1002/anie.202004934

Kenny DJ, Plichta DR, Shungin D, Koppel N, Hall AB, Fu B, Vasan RS, Shaw SY, Vlamakis H, Balskus EP, Xavier RJ

Cholesterol Metabolism by Uncultured Human Gut Bacteria Influences Host Cholesterol Level.
Cell Host Microbe. 2020;28(2):245-257.e6 - PMID: 32544460 - PMCID: PMC7435688 - DOI: 10.1016/j.chom.2020.05.013

Varma M, Kadoki M, Lefkovith A, Conway KL, Gao K, Mohanan V, Tusi BK, Graham DB, Latorre IJ, Tolonen AC, Khor B, Ng A, Xavier RJ

Cell Type- and Stimulation-Dependent Transcriptional Programs Regulated by Atg16L1 and Its Crohn's Disease Risk Variant T300A.
J Immunol. 2020;205(2):414-424 - PMID: 32522834 - PMCID: PMC7364322 - DOI: 10.4049/jimmunol.1900750

Kim W, Zou G, Pan W, Fricke N, Faizi HA, Kim SM, Khader R, Li S, Lee K, Escorba I, Vlahovska PM, Gao H, Ausubel FM, Mylonakis E

The Neutrally Charged Diarylurea Compound PQ401 Kills Antibiotic-Resistant and Antibiotic-Tolerant Staphylococcus aureus.
MBio. 2020;11(3):ePub - PMID: 32605985 - PMCID: PMC7327171 - DOI: 10.1128/mBio.01140-20

Kindt JT, Szostak JW, Wang A

Bulk Self-Assembly of Giant, Unilamellar Vesicles.
ACS Nano. 2020;14(11):14627-14634 - PMID: 32602696 - PMCID: PMC8172239 - DOI: 10.1021/acsnano.0c03125
Total: 2489