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Keefe AD, Szostak JW

Functional proteins from a random-sequence library.

Nature. 2001;410(6829):715-8 - PMID: 11287961 - PMCID: PMC4476321 - DOI: 10.1038/35070613
Wilson DS, Keefe AD, Szostak JW

The use of mRNA display to select high-affinity protein-binding peptides.

Proc Natl Acad Sci U S A. 2001;98(7):3750-5 - PMID: 11274392 - PMCID: PMC31124 - DOI: 10.1073/pnas.061028198
Pierce SB, Costa M, Wisotzkey R, Devadhar S, Homburger SA, Buchman AR, Ferguson KC, Heller J, Platt DM, Pasquinelli AA, Liu LX, Doberstein SK, Ruvkun G

Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family.

Genes Dev. 2001;15(6):672-86 - PMID: 11274053 - PMCID: PMC312654 - DOI: 10.1101/gad.867301
Bürglin TR, Ruvkun G

Regulation of ectodermal and excretory function by the C. elegans POU homeobox gene ceh-6.

Development. 2001;128(5):779-90 - PMID: 11171402 - DOI: 10.1242/dev.128.5.779
Yu YM, Ryan CM, Castillo L, Lu XM, Beaumier L, Tompkins RG, Young VR

Arginine and ornithine kinetics in severely burned patients: increased rate of arginine disposal.

Am J Physiol Endocrinol Metab. 2001;280(3):E509-17 - PMID: 11171607 - DOI: 10.1152/ajpendo.2001.280.3.E509
Rigotti A, Freeman MW

Manipulating intestinal cholesterol absorption and hepatic cholesterol and bile acid metabolism by activation of deorphanized nuclear receptors.

Gastroenterology. 2001;120(4):1054-5 - PMID: 11231965 - DOI: 10.1016/s0016-5085(01)83919-6
Aballay A, Ausubel FM

Programmed cell death mediated by ced-3 and ced-4 protects Caenorhabditis elegans from Salmonella typhimurium-mediated killing.

Proc Natl Acad Sci U S A. 2001;98(5):2735-9 - PMID: 11226309 - PMCID: PMC30208 - DOI: 10.1073/pnas.041613098
Merscher S, Funke B, Epstein JA, Heyer J, Puech A, Lu MM, Xavier RJ, Demay MB, Russell RG, Factor S, Tokooya K, Jore BS, Lopez M, Pandita RK, Lia M, Carrion D, Xu H, Schorle H, Kobler JB, Scambler P, Wynshaw-Boris A, Skoultchi AI, Morrow BE, Kucherlapati R

TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome.

Cell. 2001;104(4):619-29 - PMID: 11239417 - DOI: 10.1016/s0092-8674(01)00247-1
Sachidanandam R, Weissman D, Schmidt SC, Kakol JM, Stein LD, Marth G, Sherry S, Mullikin JC, Mortimore BJ, Willey DL, Hunt SE, Cole CG, Coggill PC, Rice CM, Ning Z, Rogers J, Bentley DR, Kwok PY, Mardis ER, Yeh RT, Schultz B, Cook L, Davenport R, Dante M, Fulton L, Hillier L, Waterston RH, McPherson JD, Gilman B, Schaffner S, Van Etten WJ, Reich D, Higgins J, Daly MJ, Blumenstiel B, Baldwin J, Stange-Thomann N, Zody MC, Linton L, Lander ES, Altshuler D,

A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms.

Nature. 2001;409(6822):928-33 - PMID: 11237013 - DOI: 10.1038/35057149
Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, Devon K, Dewar K, Doyle M, FitzHugh W, Funke R, Gage D, Harris K, Heaford A, Howland J, Kann L, Lehoczky J, LeVine R, McEwan P, McKernan K, Meldrim J, Mesirov JP, Miranda C, Morris W, Naylor J, Raymond C, Rosetti M, Santos R, Sheridan A, Sougnez C, Stange-Thomann N, Stojanovic N, Subramanian A, Wyman D, Rogers J, Sulston J, Ainscough R, Beck S, Bentley D, Burton J, Clee C, Carter N, Coulson A, Deadman R, Deloukas P, Dunham A, Dunham I, Durbin R, French L, Grafham D, Gregory S, Hubbard T, Humphray S, Hunt A, Jones M, Lloyd C, McMurray A, Matthews L, Mercer S, Milne S, Mullikin JC, Mungall A, Plumb R, Ross M, Shownkeen R, Sims S, Waterston RH, Wilson RK, Hillier LW, McPherson JD, Marra MA, Mardis ER, Fulton LA, Chinwalla AT, Pepin KH, Gish WR, Chissoe SL, Wendl MC, Delehaunty KD, Miner TL, Delehaunty A, Kramer JB, Cook LL, Fulton RS, Johnson DL, Minx PJ, Clifton SW, Hawkins T, Branscomb E, Predki P, Richardson P, Wenning S, Slezak T, Doggett N, Cheng JF, Olsen A, Lucas S, Elkin C, Uberbacher E, Frazier M, Gibbs RA, Muzny DM, Scherer SE, Bouck JB, Sodergren EJ, Worley KC, Rives CM, Gorrell JH, Metzker ML, Naylor SL, Kucherlapati RS, Nelson DL, Weinstock GM, Sakaki Y, Fujiyama A, Hattori M, Yada T, Toyoda A, Itoh T, Kawagoe C, Watanabe H, Totoki Y, Taylor T, Weissenbach J, Heilig R, Saurin W, Artiguenave F, Brottier P, Bruls T, Pelletier E, Robert C, Wincker P, Smith DR, Doucette-Stamm L, Rubenfield M, Weinstock K, Lee HM, Dubois J, Rosenthal A, Platzer M, Nyakatura G, Taudien S, Rump A, Yang H, Yu J, Wang J, Huang G, Gu J, Hood L, Rowen L, Madan A, Qin S, Davis RW, Federspiel NA, Abola AP, Proctor MJ, Myers RM, Schmutz J, Dickson M, Grimwood J, Cox DR, Olson MV, Kaul R, Raymond C, Shimizu N, Kawasaki K, Minoshima S, Evans GA, Athanasiou M, Schultz R, Roe BA, Chen F, Pan H, Ramser J, Lehrach H, Reinhardt R, McCombie WR, de la Bastide M, Dedhia N, Blöcker H, Hornischer K, Nordsiek G, Agarwala R, Aravind L, Bailey JA, Bateman A, Batzoglou S, Birney E, Bork P, Brown DG, Burge CB, Cerutti L, Chen HC, Church D, Clamp M, Copley RR, Doerks T, Eddy SR, Eichler EE, Furey TS, Galagan J, Gilbert JG, Harmon C, Hayashizaki Y, Haussler D, Hermjakob H, Hokamp K, Jang W, Johnson LS, Jones TA, Kasif S, Kaspryzk A, Kennedy S, Kent WJ, Kitts P, Koonin EV, Korf I, Kulp D, Lancet D, Lowe TM, McLysaght A, Mikkelsen T, Moran JV, Mulder N, Pollara VJ, Ponting CP, Schuler G, Schultz J, Slater G, Smit AF, Stupka E, Szustakowski J, Thierry-Mieg D, Thierry-Mieg J, Wagner L, Wallis J, Wheeler R, Williams A, Wolf YI, Wolfe KH, Yang SP, Yeh RF, Collins F, Guyer MS, Peterson J, Felsenfeld A, Wetterstrand KA, Patrinos A, Morgan MJ, de Jong P, Catanese JJ, Osoegawa K, Shizuya H, Choi S, Chen YJ; International Human Genome Sequencing Consortium

Initial sequencing and analysis of the human genome.

Nature. 2001;409(6822):860-921 - PMID: 11237011 - DOI: 10.1038/35057062
Reinhart BJ, Ruvkun G

Isoform-specific mutations in the Caenorhabditis elegans heterochronic gene lin-14 affect stage-specific patterning.

Genetics. 2001;157(1):199-209 - PMID: 11139502 - PMCID: PMC1461488 - DOI: 10.1093/genetics/157.1.199
Kausch AP, Owen TP, Zachwieja SJ, Flynn AR, Sheen J

Mesophyll-specific, light and metabolic regulation of the C4 PPCZm1 promoter in transgenic maize.

Plant Mol Biol. 2001;45(1):1-15 - PMID: 11247600 - DOI: 10.1023/a:1006487326533
Moore KJ, Rosen ED, Fitzgerald ML, Randow F, Andersson LP, Altshuler D, Milstone DS, Mortensen RM, Spiegelman BM, Freeman MW

The role of PPAR-gamma in macrophage differentiation and cholesterol uptake.

Nat Med. 2001;7(1):41-7 - PMID: 11135614 - DOI: 10.1038/83328
Szostak JW, Bartel DP, Luisi PL

Synthesizing life.

Nature. 2001;409(6818):387-90 - PMID: 11201752 - DOI: 10.1038/35053176
Cahill CM, Tzivion G, Nasrin N, Ogg S, Dore J, Ruvkun G, Alexander-Bridges M

Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways.

J Biol Chem. 2001;276(16):13402-10 - PMID: 11124266 - DOI: 10.1074/jbc.M010042200
Ausubel FM

Arabidopsis genome. A milestone in plant biology.

Plant Physiol. 2000;124(4):1451-4 - PMID: 11115856 - PMCID: PMC1539293 - DOI: 10.1104/pp.124.4.1451
Plotnikova JM, Rahme LG, Ausubel FM

Pathogenesis of the human opportunistic pathogen Pseudomonas aeruginosa PA14 in Arabidopsis.

Plant Physiol. 2000;124(4):1766-74 - PMID: 11115892 - PMCID: PMC59873 - DOI: 10.1104/pp.124.4.1766
Drenkard E, Richter BG, Rozen S, Stutius LM, Angell NA, Mindrinos M, Cho RJ, Oefner PJ, Davis RW, Ausubel FM

A simple procedure for the analysis of single nucleotide polymorphisms facilitates map-based cloning in Arabidopsis.

Plant Physiol. 2000;124(4):1483-92 - PMID: 11115864 - PMCID: PMC1539302 - DOI: 10.1104/pp.124.4.1483
Tao Y, Yuan F, Leister RT, Ausubel FM, Katagiri F

Mutational analysis of the Arabidopsis nucleotide binding site-leucine-rich repeat resistance gene RPS2.

Plant Cell. 2000;12(12):2541-2554 - PMID: 11148296 - PMCID: PMC102236 - DOI: 10.1105/tpc.12.12.2541
Li Z, Kako Y, Pang L, Freeman MW, Glick JM, Wang X, Goldberg IJ

Effects of overexpression of the amino-terminal fragment of apolipoprotein B on apolipoprotein B and lipoprotein production.

J Lipid Res. 2000;41(12):1912-20 - PMID: 11108724
Wang X, Zeng W, Murakawa M, Freeman MW, Seed B

Episomal segregation of the adenovirus enhancer sequence by conditional genome rearrangement abrogates late viral gene expression.

J Virol. 2000;74(23):11296-303 - PMID: 11070029 - PMCID: PMC113234 - DOI: 10.1128/jvi.74.23.11296-11303.2000
Holler N, Zaru R, Micheau O, Thome M, Attinger A, Valitutti S, Bodmer JL, Schneider P, Seed B, Tschopp J

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule.

Nat Immunol. 2000;1(6):489-95 - PMID: 11101870 - DOI: 10.1038/82732
Wang X, Zeng W, Murakawa M, Freeman MW, Seed B

Episomal segregation of the adenovirus enhancer sequence by conditional genome rearrangement abrogates late viral gene expression.

J Virol. 2000;74(23):11296-303 - PMID: 11070029 - PMCID: PMC113234 - DOI: 10.1128/jvi.74.23.11296-11303.2000
Kagoshima H, Sommer R, Reinhart BJ, Cassata G, Ruvkun G, Bürglin TR

Graded expression of ceh-14 reporters in the hypodermis is induced by a gonadal signal.

Dev Genes Evol. 2000;210(11):564-9 - PMID: 11180807 - DOI: 10.1007/s004270000099
Pasquinelli AE, Reinhart BJ, Slack F, Martindale MQ, Kuroda MI, Maller B, Hayward DC, Ball EE, Degnan B, Müller P, Spring J, Srinivasan A, Fishman M, Finnerty J, Corbo J, Levine M, Leahy P, Davidson E, Ruvkun G

Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA.

Nature. 2000;408(6808):86-9 - PMID: 11081512 - DOI: 10.1038/35040556
Total: 2470