Publications for All Faculty
pH and Proton Sensor GPR65 Determine Susceptibility to Atopic Dermatitis.
The CDK8 inhibitor DCA promotes a tolerogenic chemical immunophenotype in CD4+ T cells via a novel CDK8-GATA3-FOXP3 pathway.
Structure-based protein function prediction using graph convolutional networks.
Translating the human microbiome: a path to improving health.
Longitudinal proteomic analysis of plasma from patients with severe COVID-19 reveal patient survival-associated signatures, tissue-specific cell death, and cell-cell interactions.
Capsular polysaccharide correlates with immune response to the human gut microbe Ruminococcus gnavus.
CRISPR prime editing with ribonucleoprotein complexes in zebrafish and primary human cells.
Dual transcriptional analysis reveals adaptation of host and pathogen to intracellular survival of Pseudomonas aeruginosa associated with urinary tract infection.
B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV.
Genetic determinants facilitating the evolution of resistance to carbapenem antibiotics.
Genome-wide enhancer maps link risk variants to disease genes.
Cytokine-specific autoantibodies shape the gut microbiome in autoimmune polyendocrine syndrome type 1.
Single-cell analyses of Crohn's disease tissues reveal intestinal intraepithelial T cells heterogeneity and altered subset distributions.
Elevated rates of horizontal gene transfer in the industrialized human microbiome.
Competition between bridged dinucleotides and activated mononucleotides determines the error frequency of nonenzymatic RNA primer extension.
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics.
γδ T cells regulate the intestinal response to nutrient sensing.
Congruent microbiome signatures in fibrosis-prone autoimmune diseases: IgG4-related disease and systemic sclerosis.
The Emergence of RNA from the Heterogeneous Products of Prebiotic Nucleotide Synthesis.
A Code of Ethics for Gene Drive Research.
In search of the RNA world on Mars.
A Potential Role for Aminoacylation in Primordial RNA Copying Chemistry.
Shielding from UV Photodamage: Implications for Surficial Origins of Life Chemistry on the Early Earth.
QRICH1 dictates the outcome of ER stress through transcriptional control of proteostasis.
Protein-bound molybdenum cofactor is bioavailable and rescues molybdenum cofactor-deficient C. elegans.