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Cheng WH, Endo A, Zhou L, Penney J, Chen HC, Arroyo A, Leon P, Nambara E, Asami T, Seo M, Koshiba T, Sheen J

A unique short-chain dehydrogenase/reductase in Arabidopsis glucose signaling and abscisic acid biosynthesis and functions.
Plant Cell. 2002;14(11):2723-43 - PMID: 12417697 - PMCID: PMC152723 - DOI: 10.1105/tpc.006494

Wolkow CA, Muñoz MJ, Riddle DL, Ruvkun G

Insulin receptor substrate and p55 orthologous adaptor proteins function in the Caenorhabditis elegans daf-2/insulin-like signaling pathway.
J Biol Chem. 2002;277(51):49591-7 - PMID: 12393910 - DOI: 10.1074/jbc.M207866200

Kunjathoor VV, Febbraio M, Podrez EA, Moore KJ, Andersson L, Koehn S, Rhee JS, Silverstein R, Hoff HF, Freeman MW

Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages.
J Biol Chem. 2002;277(51):49982-8 - PMID: 12376530 - DOI: 10.1074/jbc.M209649200

Yang KK, Dorner BG, Merkel U, Ryffel B, Schütt C, Golenbock D, Freeman MW, Jack RS

Neutrophil influx in response to a peritoneal infection with Salmonella is delayed in lipopolysaccharide-binding protein or CD14-deficient mice.
J Immunol. 2002;169(8):4475-80 - PMID: 12370383 - DOI: 10.4049/jimmunol.169.8.4475

Henneke P, Takeuchi O, Malley R, Lien E, Ingalls RR, Freeman MW, Mayadas T, Nizet V, Akira S, Kasper DL, Golenbock DT

Cellular activation, phagocytosis, and bactericidal activity against group B streptococcus involve parallel myeloid differentiation factor 88-dependent and independent signaling pathways.
J Immunol. 2002;169(7):3970-7 - PMID: 12244198 - DOI: 10.4049/jimmunol.169.7.3970

Szostak JW

Molecular biology: RNA gets a grip on translation.
Nature. 2002;419(6910):890-1 - PMID: 12410294 - DOI: 10.1038/419890a

Sifri CD, Mylonakis E, Singh KV, Qin X, Garsin DA, Murray BE, Ausubel FM, Calderwood SB

Virulence effect of Enterococcus faecalis protease genes and the quorum-sensing locus fsr in Caenorhabditis elegans and mice.
Infect Immun. 2002;70(10):5647-50 - PMID: 12228293 - PMCID: PMC128331 - DOI: 10.1128/iai.70.10.5647-5650.2002

Xu J, Fei Z, Yu YM, Xu W, Rhodes A, Tompkins RG, Schulz JT

In vivo rabbit hindquarter model for assessment of regional burn hypermetabolism.
J Appl Physiol. 2003;94(1):135-40 - PMID: 12391055 - DOI: 10.1152/japplphysiol.00513.2002

Ryan CM, Schoenfeld DA, Malloy M, Schulz JT, Sheridan RL, Tompkins RG

Use of Integra artificial skin is associated with decreased length of stay for severely injured adult burn survivors.
J Burn Care Rehabil. 2002;23(5):311-7 - PMID: 12352131 - DOI: 10.1097/00004630-200209000-00002

Moore KJ, El Khoury J, Medeiros LA, Terada K, Geula C, Luster AD, Freeman MW

A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid.
J Biol Chem. 2002;277(49):47373-9 - PMID: 12239221 - DOI: 10.1074/jbc.M208788200

MW Freeman

The Treatment of Dyslipidemia: LDL Reduction and Beyond
In Endocrinology Rounds. 2002;1, Issue 8:ePub

Weber JM, Sheridan RL, Schulz JT, Tompkins RG, Ryan CM

Effectiveness of bacteria-controlled nursing units in preventing cross-colonization with resistant bacteria in severely burned children.
Infect Control Hosp Epidemiol. 2002;23(9):549-51 - PMID: 12269456 - DOI: 10.1086/502106

Baggio R, Burgstaller P, Hale SP, Putney AR, Lane M, Lipovsek D, Wright MC, Roberts RW, Liu R, Szostak JW, Wagner RW

Identification of epitope-like consensus motifs using mRNA display.
J Mol Recognit. 2002;15(3):126-34 - PMID: 12203838 - DOI: 10.1002/jmr.567

Davis JH, Szostak JW

Isolation of high-affinity GTP aptamers from partially structured RNA libraries.
Proc Natl Acad Sci U S A. 2002;99(18):11616-21 - PMID: 12185247 - PMCID: PMC129318 - DOI: 10.1073/pnas.182095699

Sze JY, Zhang S, Li J, Ruvkun G

The C. elegans POU-domain transcription factor UNC-86 regulates the tph-1 tryptophan hydroxylase gene and neurite outgrowth in specific serotonergic neurons.
Development. 2002;129(16):3901-11 - PMID: 12135927 - DOI: 10.1242/dev.129.16.3901

Mylonakis E, Engelbert M, Qin X, Sifri CD, Murray BE, Ausubel FM, Gilmore MS, Calderwood SB

The Enterococcus faecalis fsrB gene, a key component of the fsr quorum-sensing system, is associated with virulence in the rabbit endophthalmitis model.
Infect Immun. 2002;70(8):4678-81 - PMID: 12117982 - PMCID: PMC128160 - DOI: 10.1128/iai.70.8.4678-4681.2002

Kim DH, Feinbaum R, Alloing G, Emerson FE, Garsin DA, Inoue H, Tanaka-Hino M, Hisamoto N, Matsumoto K, Tan MW, Ausubel FM

A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity.
Science. 2002;297(5581):623-6 - PMID: 12142542 - DOI: 10.1126/science.1073759

Lee SS, Ruvkun G

Longevity: don't hold your breath.
Nature. 2002;418(6895):287-8 - PMID: 12124610 - DOI: 10.1038/418287a

Fitzgerald ML, Morris AL, Rhee JS, Andersson LP, Mendez AJ, Freeman MW

Naturally occurring mutations in the largest extracellular loops of ABCA1 can disrupt its direct interaction with apolipoprotein A-I.
J Biol Chem. 2002;277(36):33178-87 - PMID: 12084722 - DOI: 10.1074/jbc.M204996200

Schiffmann R, Mankin H, Dambrosia JM, Xavier RJ, Kreps C, Hill SC, Barton NW, Rosenthal DI

Decreased bone density in splenectomized Gaucher patients receiving enzyme replacement therapy.
Blood Cells Mol Dis. 2002;28(2):288-96 - PMID: 12064924 - DOI: 10.1006/bcmd.2002.0517

Rolland F, Moore B, Sheen J

Sugar sensing and signaling in plants.
Plant Cell. 2002;14 Suppl:S185-205 - PMID: 12045277 - PMCID: PMC151255 - DOI: 10.1105/tpc.010455

Hwang I, Chen HC, Sheen J

Two-component signal transduction pathways in Arabidopsis.
Plant Physiol. 2002;129(2):500-15 - PMID: 12068096 - PMCID: PMC161668 - DOI: 10.1104/pp.005504

Cheng SH, Willmann MR, Chen HC, Sheen J

Calcium signaling through protein kinases. The Arabidopsis calcium-dependent protein kinase gene family.
Plant Physiol. 2002;129(2):469-85 - PMID: 12068094 - PMCID: PMC1540234 - DOI: 10.1104/pp.005645

Cui J, Jander G, Racki LR, Kim PD, Pierce NE, Ausubel FM

Signals involved in Arabidopsis resistance to Trichoplusia ni caterpillars induced by virulent and avirulent strains of the phytopathogen Pseudomonas syringae.
Plant Physiol. 2002;129(2):551-64 - PMID: 12068100 - PMCID: PMC161673 - DOI: 10.1104/pp.010815

Sheen J

Phosphorelay and transcription control in cytokinin signal transduction.
Science. 2002;296(5573):1650-2 - PMID: 12040183 - DOI: 10.1126/science.1071883
Total: 2485