Publications for All Faculty

Sort by:
Reset
Ashrafi K, Chang FY, Watts JL, Fraser AG, Kamath RS, Ahringer J, Ruvkun G

Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes.

Nature. 2003;421(6920):268-72 - PMID: 12529643 - DOI: 10.1038/nature01279
Ferrari S, Vairo D, Ausubel FM, Cervone F, De Lorenzo G

Tandemly duplicated Arabidopsis genes that encode polygalacturonase-inhibiting proteins are regulated coordinately by different signal transduction pathways in response to fungal infection.

Plant Cell. 2003;15(1):93-106 - PMID: 12509524 - PMCID: PMC143454 - DOI: 10.1105/tpc.005165
Aballay A, Drenkard E, Hilbun LR, Ausubel FM

Caenorhabditis elegans innate immune response triggered by Salmonella enterica requires intact LPS and is mediated by a MAPK signaling pathway.

Curr Biol. 2003;13(1):47-52 - PMID: 12526744 - DOI: 10.1016/s0960-9822(02)01396-9
Chaput JC, Ichida JK, Szostak JW

DNA polymerase-mediated DNA synthesis on a TNA template.

J Am Chem Soc. 2003;125(4):856-7 - PMID: 12537469 - DOI: 10.1021/ja028589k
Mouse Genome Sequencing Consortium, Waterston RH, Lindblad-Toh K, Birney E, Rogers J, Abril JF, Agarwal P, Agarwala R, Ainscough R, Alexandersson M, An P, Antonarakis SE, Attwood J, Baertsch R, Bailey J, Barlow K, Beck S, Berry E, Birren B, Bloom T, Bork P, Botcherby M, Bray N, Brent MR, Brown DG, Brown SD, Bult C, Burton J, Butler J, Campbell RD, Carninci P, Cawley S, Chiaromonte F, Chinwalla AT, Church DM, Clamp M, Clee C, Collins FS, Cook LL, Copley RR, Coulson A, Couronne O, Cuff J, Curwen V, Cutts T, Daly M, David R, Davies J, Delehaunty KD, Deri J, Dermitzakis ET, Dewey C, Dickens NJ, Diekhans M, Dodge S, Dubchak I, Dunn DM, Eddy SR, Elnitski L, Emes RD, Eswara P, Eyras E, Felsenfeld A, Fewell GA, Flicek P, Foley K, Frankel WN, Fulton LA, Fulton RS, Furey TS, Gage D, Gibbs RA, Glusman G, Gnerre S, Goldman N, Goodstadt L, Grafham D, Graves TA, Green ED, Gregory S, Guigó R, Guyer M, Hardison RC, Haussler D, Hayashizaki Y, Hillier LW, Hinrichs A, Hlavina W, Holzer T, Hsu F, Hua A, Hubbard T, Hunt A, Jackson I, Jaffe DB, Johnson LS, Jones M, Jones TA, Joy A, Kamal M, Karlsson EK, Karolchik D, Kasprzyk A, Kawai J, Keibler E, Kells C, Kent WJ, Kirby A, Kolbe DL, Korf I, Kucherlapati RS, Kulbokas EJ, Kulp D, Landers T, Leger JP, Leonard S, Letunic I, Levine R, Li J, Li M, Lloyd C, Lucas S, Ma B, Maglott DR, Mardis ER, Matthews L, Mauceli E, Mayer JH, McCarthy M, McCombie WR, McLaren S, McLay K, McPherson JD, Meldrim J, Meredith B, Mesirov JP, Miller W, Miner TL, Mongin E, Montgomery KT, Morgan M, Mott R, Mullikin JC, Muzny DM, Nash WE, Nelson JO, Nhan MN, Nicol R, Ning Z, Nusbaum C, O'Connor MJ, Okazaki Y, Oliver K, Overton-Larty E, Pachter L, Parra G, Pepin KH, Peterson J, Pevzner P, Plumb R, Pohl CS, Poliakov A, Ponce TC, Ponting CP, Potter S, Quail M, Reymond A, Roe BA, Roskin KM, Rubin EM, Rust AG, Santos R, Sapojnikov V, Schultz B, Schultz J, Schwartz MS, Schwartz S, Scott C, Seaman S, Searle S, Sharpe T, Sheridan A, Shownkeen R, Sims S, Singer JB, Slater G, Smit A, Smith DR, Spencer B, Stabenau A, Stange-Thomann N, Sugnet C, Suyama M, Tesler G, Thompson J, Torrents D, Trevaskis E, Tromp J, Ucla C, Ureta-Vidal A, Vinson JP, Von Niederhausern AC, Wade CM, Wall M, Weber RJ, Weiss RB, Wendl MC, West AP, Wetterstrand K, Wheeler R, Whelan S, Wierzbowski J, Willey D, Williams S, Wilson RK, Winter E, Worley KC, Wyman D, Yang S, Yang SP, Zdobnov EM, Zody MC, Lander ES

Initial sequencing and comparative analysis of the mouse genome.

Nature. 2002;420(6915):520-62 - PMID: 12466850 - DOI: 10.1038/nature01262
Lee SS, Lee RY, Fraser AG, Kamath RS, Ahringer J, Ruvkun G

A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity.

Nat Genet. 2003;33(1):40-8 - PMID: 12447374 - DOI: 10.1038/ng1056
Mylonakis E, Ausubel FM, Perfect JR, Heitman J, Calderwood SB

Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis.

Proc Natl Acad Sci U S A. 2002;99(24):15675-80 - PMID: 12438649 - PMCID: PMC137775 - DOI: 10.1073/pnas.232568599
Cheng WH, Endo A, Zhou L, Penney J, Chen HC, Arroyo A, Leon P, Nambara E, Asami T, Seo M, Koshiba T, Sheen J

A unique short-chain dehydrogenase/reductase in Arabidopsis glucose signaling and abscisic acid biosynthesis and functions.

Plant Cell. 2002;14(11):2723-43 - PMID: 12417697 - PMCID: PMC152723 - DOI: 10.1105/tpc.006494
Wolkow CA, Muñoz MJ, Riddle DL, Ruvkun G

Insulin receptor substrate and p55 orthologous adaptor proteins function in the Caenorhabditis elegans daf-2/insulin-like signaling pathway.

J Biol Chem. 2002;277(51):49591-7 - PMID: 12393910 - DOI: 10.1074/jbc.M207866200
Kunjathoor VV, Febbraio M, Podrez EA, Moore KJ, Andersson L, Koehn S, Rhee JS, Silverstein R, Hoff HF, Freeman MW

Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages.

J Biol Chem. 2002;277(51):49982-8 - PMID: 12376530 - DOI: 10.1074/jbc.M209649200
Sifri CD, Mylonakis E, Singh KV, Qin X, Garsin DA, Murray BE, Ausubel FM, Calderwood SB

Virulence effect of Enterococcus faecalis protease genes and the quorum-sensing locus fsr in Caenorhabditis elegans and mice.

Infect Immun. 2002;70(10):5647-50 - PMID: 12228293 - PMCID: PMC128331 - DOI: 10.1128/iai.70.10.5647-5650.2002
Yang KK, Dorner BG, Merkel U, Ryffel B, Schütt C, Golenbock D, Freeman MW, Jack RS

Neutrophil influx in response to a peritoneal infection with Salmonella is delayed in lipopolysaccharide-binding protein or CD14-deficient mice.

J Immunol. 2002;169(8):4475-80 - PMID: 12370383 - DOI: 10.4049/jimmunol.169.8.4475
Henneke P, Takeuchi O, Malley R, Lien E, Ingalls RR, Freeman MW, Mayadas T, Nizet V, Akira S, Kasper DL, Golenbock DT

Cellular activation, phagocytosis, and bactericidal activity against group B streptococcus involve parallel myeloid differentiation factor 88-dependent and independent signaling pathways.

J Immunol. 2002;169(7):3970-7 - PMID: 12244198 - DOI: 10.4049/jimmunol.169.7.3970
Szostak JW

Molecular biology: RNA gets a grip on translation.

Nature. 2002;419(6910):890-1 - PMID: 12410294 - DOI: 10.1038/419890a
Ryan CM, Schoenfeld DA, Malloy M, Schulz JT, Sheridan RL, Tompkins RG

Use of Integra artificial skin is associated with decreased length of stay for severely injured adult burn survivors.

J Burn Care Rehabil. 2002;23(5):311-7 - PMID: 12352131 - DOI: 10.1097/00004630-200209000-00002
Xu J, Fei Z, Yu YM, Xu W, Rhodes A, Tompkins RG, Schulz JT

In vivo rabbit hindquarter model for assessment of regional burn hypermetabolism.

J Appl Physiol. 2003;94(1):135-40 - PMID: 12391055 - DOI: 10.1152/japplphysiol.00513.2002
Moore KJ, El Khoury J, Medeiros LA, Terada K, Geula C, Luster AD, Freeman MW

A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid.

J Biol Chem. 2002;277(49):47373-9 - PMID: 12239221 - DOI: 10.1074/jbc.M208788200
Weber JM, Sheridan RL, Schulz JT, Tompkins RG, Ryan CM

Effectiveness of bacteria-controlled nursing units in preventing cross-colonization with resistant bacteria in severely burned children.

Infect Control Hosp Epidemiol. 2002;23(9):549-51 - PMID: 12269456 - DOI: 10.1086/502106
MW Freeman

The Treatment of Dyslipidemia: LDL Reduction and Beyond

In Endocrinology Rounds. 2002;1, Issue 8:ePub
Baggio R, Burgstaller P, Hale SP, Putney AR, Lane M, Lipovsek D, Wright MC, Roberts RW, Liu R, Szostak JW, Wagner RW

Identification of epitope-like consensus motifs using mRNA display.

J Mol Recognit. 2002;15(3):126-34 - PMID: 12203838 - DOI: 10.1002/jmr.567
Davis JH, Szostak JW

Isolation of high-affinity GTP aptamers from partially structured RNA libraries.

Proc Natl Acad Sci U S A. 2002;99(18):11616-21 - PMID: 12185247 - PMCID: PMC129318 - DOI: 10.1073/pnas.182095699
Sze JY, Zhang S, Li J, Ruvkun G

The C. elegans POU-domain transcription factor UNC-86 regulates the tph-1 tryptophan hydroxylase gene and neurite outgrowth in specific serotonergic neurons.

Development. 2002;129(16):3901-11 - PMID: 12135927 - DOI: 10.1242/dev.129.16.3901
Mylonakis E, Engelbert M, Qin X, Sifri CD, Murray BE, Ausubel FM, Gilmore MS, Calderwood SB

The Enterococcus faecalis fsrB gene, a key component of the fsr quorum-sensing system, is associated with virulence in the rabbit endophthalmitis model.

Infect Immun. 2002;70(8):4678-81 - PMID: 12117982 - PMCID: PMC128160 - DOI: 10.1128/iai.70.8.4678-4681.2002
Lee SS, Ruvkun G

Longevity: don't hold your breath.

Nature. 2002;418(6895):287-8 - PMID: 12124610 - DOI: 10.1038/418287a
Kim DH, Feinbaum R, Alloing G, Emerson FE, Garsin DA, Inoue H, Tanaka-Hino M, Hisamoto N, Matsumoto K, Tan MW, Ausubel FM

A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity.

Science. 2002;297(5581):623-6 - PMID: 12142542 - DOI: 10.1126/science.1073759
Total: 2467