Publications for All Faculty

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Vaish NK, Larralde R, Fraley AW, Szostak JW, McLaughlin LW

A novel, modification-dependent ATP-binding aptamer selected from an RNA library incorporating a cationic functionality.
Biochemistry. 2003;42(29):8842-51 - PMID: 12873145 - DOI: 10.1021/bi027354i

Lau GW, Goumnerov BC, Walendziewicz CL, Hewitson J, Xiao W, Mahajan-Miklos S, Tompkins RG, Perkins LA, Rahme LG

The Drosophila melanogaster toll pathway participates in resistance to infection by the gram-negative human pathogen Pseudomonas aeruginosa.
Infect Immun. 2003;71(7):4059-66 - PMID: 12819096 - PMCID: PMC162001 - DOI: 10.1128/iai.71.7.4059-4066.2003

Pasquinelli AE, McCoy A, Jiménez E, Saló E, Ruvkun G, Martindale MQ, Baguñà J

Expression of the 22 nucleotide let-7 heterochronic RNA throughout the Metazoa: a role in life history evolution?
Evol Dev. 2003;5(4):372-8 - PMID: 12823453 - DOI: 10.1046/j.1525-142x.2003.03044.x

El Khoury JB, Moore KJ, Means TK, Leung J, Terada K, Toft M, Freeman MW, Luster AD

CD36 mediates the innate host response to beta-amyloid.
J Exp Med. 2003;197(12):1657-66 - PMID: 12796468 - PMCID: PMC2193948 - DOI: 10.1084/jem.20021546

Garsin DA, Villanueva JM, Begun J, Kim DH, Sifri CD, Calderwood SB, Ruvkun G, Ausubel FM

Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens.
Science. 2003;300(5627):1921 - PMID: 12817143 - DOI: 10.1126/science.1080147

Garsin DA, Villanueva JM, Begun J, Kim DH, Sifri CD, Calderwood SB, Ruvkun G, Ausubel FM

Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens.
Science. 2003;300(5627):1921 - PMID: 12817143 - DOI: 10.1126/science.1080147

Lowe CJ, Wu M, Salic A, Evans L, Lander E, Stange-Thomann N, Gruber CE, Gerhart J, Kirschner M

Anteroposterior patterning in hemichordates and the origins of the chordate nervous system.
Cell. 2003;113(7):853-65 - PMID: 12837244 - DOI: 10.1016/s0092-8674(03)00469-0

Szostak JW

Functional information: Molecular messages.
Nature. 2003;423(6941):689 - PMID: 12802312 - DOI: 10.1038/423689a

Mylonakis E, Ausubel FM, Tang RJ, Calderwood SB

The art of serendipity: killing of Caenorhabditis elegans by human pathogens as a model of bacterial and fungal pathogenesis.
Expert Rev Anti Infect Ther. 2003;1(1):167-73 - PMID: 15482109 - DOI: 10.1586/14787210.1.1.167

Brown E, McKee T, diTomaso E, Pluen A, Seed B, Boucher Y, Jain RK

Dynamic imaging of collagen and its modulation in tumors in vivo using second-harmonic generation.
Nat Med. 2003;9(6):796-800 - PMID: 12754503 - DOI: 10.1038/nm879

Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J

Computational and experimental identification of C. elegans microRNAs.
Mol Cell. 2003;11(5):1253-63 - PMID: 12769849 - DOI: 10.1016/s1097-2765(03)00153-9

Wang X, Seed B

Selection of oligonucleotide probes for protein coding sequences.
Bioinformatics. 2003;19(7):796-802 - PMID: 12724288 - DOI: 10.1093/bioinformatics/btg086

Miyata S, Casey M, Frank DW, Ausubel FM, Drenkard E

Use of the Galleria mellonella caterpillar as a model host to study the role of the type III secretion system in Pseudomonas aeruginosa pathogenesis.
Infect Immun. 2003;71(5):2404-13 - PMID: 12704110 - PMCID: PMC153283 - DOI: 10.1128/iai.71.5.2404-2413.2003

Shito M, Tilles AW, Tompkins RG, Yarmush ML, Toner M

Efficacy of an extracorporeal flat-plate bioartificial liver in treating fulminant hepatic failure.
J Surg Res. 2003;111(1):53-62 - PMID: 12842448 - DOI: 10.1016/s0022-4804(03)00048-9

Lee SS, Kennedy S, Tolonen AC, Ruvkun G

DAF-16 target genes that control C. elegans life-span and metabolism.
Science. 2003;300(5619):644-7 - PMID: 12690206 - DOI: 10.1126/science.1083614

Moore B, Zhou L, Rolland F, Hall Q, Cheng WH, Liu YX, Hwang I, Jones T, Sheen J

Role of the Arabidopsis glucose sensor HXK1 in nutrient, light, and hormonal signaling.
Science. 2003;300(5617):332-6 - PMID: 12690200 - DOI: 10.1126/science.1080585

Galagan JE, Calvo SE, Borkovich KA, Selker EU, Read ND, Jaffe D, FitzHugh W, Ma LJ, Smirnov S, Purcell S, Rehman B, Elkins T, Engels R, Wang S, Nielsen CB, Butler J, Endrizzi M, Qui D, Ianakiev P, Bell-Pedersen D, Nelson MA, Werner-Washburne M, Selitrennikoff CP, Kinsey JA, Braun EL, Zelter A, Schulte U, Kothe GO, Jedd G, Mewes W, Staben C, Marcotte E, Greenberg D, Roy A, Foley K, Naylor J, Stange-Thomann N, Barrett R, Gnerre S, Kamal M, Kamvysselis M, Mauceli E, Bielke C, Rudd S, Frishman D, Krystofova S, Rasmussen C, Metzenberg RL, Perkins DD, Kroken S, Cogoni C, Macino G, Catcheside D, Li W, Pratt RJ, Osmani SA, DeSouza CP, Glass L, Orbach MJ, Berglund JA, Voelker R, Yarden O, Plamann M, Seiler S, Dunlap J, Radford A, Aramayo R, Natvig DO, Alex LA, Mannhaupt G, Ebbole DJ, Freitag M, Paulsen I, Sachs MS, Lander ES, Nusbaum C, Birren B

The genome sequence of the filamentous fungus Neurospora crassa.
Nature. 2003;422(6934):859-68 - PMID: 12712197 - DOI: 10.1038/nature01554

Huang Z, Szostak JW

Selective labeling and detection of specific RNAs in an RNA mixture.
Anal Biochem. 2003;315(1):129-33 - PMID: 12672421 - DOI: 10.1016/s0003-2697(02)00701-7

Sifri CD, Begun J, Ausubel FM, Calderwood SB

Caenorhabditis elegans as a model host for Staphylococcus aureus pathogenesis.
Infect Immun. 2003;71(4):2208-17 - PMID: 12654843 - PMCID: PMC152095 - DOI: 10.1128/iai.71.4.2208-2217.2003

Tilles AW, Berthiaume F, Yarmush ML, Tompkins RG, Toner M

Bioengineering of liver assist devices.
J Hepatobiliary Pancreat Surg. 2003;9(6):686-96 - PMID: 12658402 - DOI: 10.1007/s005340200095

Li W, Kennedy SG, Ruvkun G

daf-28 encodes a C. elegans insulin superfamily member that is regulated by environmental cues and acts in the DAF-2 signaling pathway.
Genes Dev. 2003;17(7):844-58 - PMID: 12654727 - PMCID: PMC196030 - DOI: 10.1101/gad.1066503

Yang Y, Seed B

Site-specific gene targeting in mouse embryonic stem cells with intact bacterial artificial chromosomes.
Nat Biotechnol. 2003;21(4):447-51 - PMID: 12627171 - DOI: 10.1038/nbt803

León P, Sheen J

Sugar and hormone connections.
Trends Plant Sci. 2003;8(3):110-6 - PMID: 12663220 - DOI: 10.1016/S1360-1385(03)00011-6

Ambros V, Bartel B, Bartel DP, Burge CB, Carrington JC, Chen X, Dreyfuss G, Eddy SR, Griffiths-Jones S, Marshall M, Matzke M, Ruvkun G, Tuschl T

A uniform system for microRNA annotation.
RNA. 2003;9(3):277-9 - PMID: 12592000 - PMCID: PMC1370393 - DOI: 10.1261/rna.2183803

Xu Y, Stange-Thomann N, Weber G, Bo R, Dodge S, David RG, Foley K, Beheshti J, Harris NL, Birren B, Lander ES, Meyerson M

Pathogen discovery from human tissue by sequence-based computational subtraction.
Genomics. 2003;81(3):329-35 - PMID: 12659816 - DOI: 10.1016/s0888-7543(02)00043-5
Total: 2498