Publications for All Faculty

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Hurt JA, Thibodeau SA, Hirsh AS, Pabo CO, Joung JK

Highly specific zinc finger proteins obtained by directed domain shuffling and cell-based selection.
Proc Natl Acad Sci U S A. 2003;100(21):12271-6 - PMID: 14527993 - PMCID: PMC218748 - DOI: 10.1073/pnas.2135381100

Yanagisawa S, Yoo SD, Sheen J

Differential regulation of EIN3 stability by glucose and ethylene signalling in plants.
Nature. 2003;425(6957):521-5 - PMID: 14523448 - DOI: 10.1038/nature01984

Kim WS, Ordija CM, Freeman MW

Activation of signaling pathways by putative scavenger receptor class A (SR-A) ligands requires CD14 but not SR-A.
Biochem Biophys Res Commun. 2003;310(2):542-9 - PMID: 14521944 - DOI: 10.1016/j.bbrc.2003.09.049

Hanczyc MM, Fujikawa SM, Szostak JW

Experimental models of primitive cellular compartments: encapsulation, growth, and division.
Science. 2003;302(5645):618-22 - PMID: 14576428 - PMCID: PMC4484575 - DOI: 10.1126/science.1089904

Chen CL, Fei Z, Carter EA, Lu XM, Hu RH, Young VR, Tompkins RG, Yu YM

Metabolic fate of extrahepatic arginine in liver after burn injury.
Metabolism. 2003;52(10):1232-9 - PMID: 14564672 - DOI: 10.1016/s0026-0495(03)00282-8

Pawlik TM, Carter EA, Bode BP, Fischman AJ, Tompkins RG

Central role of interleukin-6 in burn induced stimulation of hepatic amino acid transport.
Int J Mol Med. 2003;12(4):541-8 - PMID: 12964032

Lichtenthaler SF, Dominguez DI, Westmeyer GG, Reiss K, Haass C, Saftig P, De Strooper B, Seed B

The cell adhesion protein P-selectin glycoprotein ligand-1 is a substrate for the aspartyl protease BACE1.
J Biol Chem. 2003;278(49):48713-9 - PMID: 14507929 - DOI: 10.1074/jbc.M303861200

Lucas M, Stuart LM, Savill J, Lacy-Hulbert A

Apoptotic cells and innate immune stimuli combine to regulate macrophage cytokine secretion.
J Immunol. 2003;171(5):2610-5 - PMID: 12928413 - DOI: 10.4049/jimmunol.171.5.2610

Ruvinsky I, Ruvkun G

Functional tests of enhancer conservation between distantly related species.
Development. 2003;130(21):5133-42 - PMID: 12944426 - DOI: 10.1242/dev.00711

Aspöck G, Ruvkun G, Bürglin TR

The Caenorhabditis elegans ems class homeobox gene ceh-2 is required for M3 pharynx motoneuron function.
Development. 2003;130(15):3369-78 - PMID: 12810585 - DOI: 10.1242/dev.00551

Chaput JC, Szostak JW

TNA synthesis by DNA polymerases.
J Am Chem Soc. 2003;125(31):9274-5 - PMID: 12889939 - DOI: 10.1021/ja035917n

Sze JY, Ruvkun G

Activity of the Caenorhabditis elegans UNC-86 POU transcription factor modulates olfactory sensitivity.
Proc Natl Acad Sci U S A. 2003;100(16):9560-5 - PMID: 12883006 - PMCID: PMC170957 - DOI: 10.1073/pnas.1530752100

Lutfalla G, Roest Crollius H, Stange-Thomann N, Jaillon O, Mogensen K, Monneron D

Comparative genomic analysis reveals independent expansion of a lineage-specific gene family in vertebrates: the class II cytokine receptors and their ligands in mammals and fish.
BMC Genomics. 2003;4(1):29 - PMID: 12869211 - PMCID: PMC179897 - DOI: 10.1186/1471-2164-4-29

Mizoguchi E, Xavier RJ, Reinecker HC, Uchino H, Bhan AK, Podolsky DK, Mizoguchi A

Colonic epithelial functional phenotype varies with type and phase of experimental colitis.
Gastroenterology. 2003;125(1):148-61 - PMID: 12851880 - DOI: 10.1016/s0016-5085(03)00665-6

Ferrari S, Plotnikova JM, De Lorenzo G, Ausubel FM

Arabidopsis local resistance to Botrytis cinerea involves salicylic acid and camalexin and requires EDS4 and PAD2, but not SID2, EDS5 or PAD4.
Plant J. 2003;35(2):193-205 - PMID: 12848825 - DOI: 10.1046/j.1365-313x.2003.01794.x

Bashirullah A, Pasquinelli AE, Kiger AA, Perrimon N, Ruvkun G, Thummel CS

Coordinate regulation of small temporal RNAs at the onset of Drosophila metamorphosis.
Dev Biol. 2003;259(1):1-8 - PMID: 12812783 - DOI: 10.1016/s0012-1606(03)00063-0

Vaish NK, Larralde R, Fraley AW, Szostak JW, McLaughlin LW

A novel, modification-dependent ATP-binding aptamer selected from an RNA library incorporating a cationic functionality.
Biochemistry. 2003;42(29):8842-51 - PMID: 12873145 - DOI: 10.1021/bi027354i

Lau GW, Goumnerov BC, Walendziewicz CL, Hewitson J, Xiao W, Mahajan-Miklos S, Tompkins RG, Perkins LA, Rahme LG

The Drosophila melanogaster toll pathway participates in resistance to infection by the gram-negative human pathogen Pseudomonas aeruginosa.
Infect Immun. 2003;71(7):4059-66 - PMID: 12819096 - PMCID: PMC162001 - DOI: 10.1128/iai.71.7.4059-4066.2003

Pasquinelli AE, McCoy A, Jiménez E, Saló E, Ruvkun G, Martindale MQ, Baguñà J

Expression of the 22 nucleotide let-7 heterochronic RNA throughout the Metazoa: a role in life history evolution?
Evol Dev. 2003;5(4):372-8 - PMID: 12823453 - DOI: 10.1046/j.1525-142x.2003.03044.x

El Khoury JB, Moore KJ, Means TK, Leung J, Terada K, Toft M, Freeman MW, Luster AD

CD36 mediates the innate host response to beta-amyloid.
J Exp Med. 2003;197(12):1657-66 - PMID: 12796468 - PMCID: PMC2193948 - DOI: 10.1084/jem.20021546

Garsin DA, Villanueva JM, Begun J, Kim DH, Sifri CD, Calderwood SB, Ruvkun G, Ausubel FM

Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens.
Science. 2003;300(5627):1921 - PMID: 12817143 - DOI: 10.1126/science.1080147

Garsin DA, Villanueva JM, Begun J, Kim DH, Sifri CD, Calderwood SB, Ruvkun G, Ausubel FM

Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens.
Science. 2003;300(5627):1921 - PMID: 12817143 - DOI: 10.1126/science.1080147

Lowe CJ, Wu M, Salic A, Evans L, Lander E, Stange-Thomann N, Gruber CE, Gerhart J, Kirschner M

Anteroposterior patterning in hemichordates and the origins of the chordate nervous system.
Cell. 2003;113(7):853-65 - PMID: 12837244 - DOI: 10.1016/s0092-8674(03)00469-0

Szostak JW

Functional information: Molecular messages.
Nature. 2003;423(6941):689 - PMID: 12802312 - DOI: 10.1038/423689a

Mylonakis E, Ausubel FM, Tang RJ, Calderwood SB

The art of serendipity: killing of Caenorhabditis elegans by human pathogens as a model of bacterial and fungal pathogenesis.
Expert Rev Anti Infect Ther. 2003;1(1):167-73 - PMID: 15482109 - DOI: 10.1586/14787210.1.1.167
Total: 2489