Publications for All Faculty

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Nguyen-Hackley DH, Ramm E, Taylor CM, Joung JK, Dervan PB, Pabo CO

Allosteric inhibition of zinc-finger binding in the major groove of DNA by minor-groove binding ligands.
Biochemistry. 2004;43(13):3880-90 - PMID: 15049695 - DOI: 10.1021/bi030223c

Carothers JM, Oestreich SC, Davis JH, Szostak JW

Informational complexity and functional activity of RNA structures.
J Am Chem Soc. 2004;126(16):5130-7 - PMID: 15099096 - PMCID: PMC5042360 - DOI: 10.1021/ja031504a

Apidianakis Y, Rahme LG, Heitman J, Ausubel FM, Calderwood SB, Mylonakis E

Challenge of Drosophila melanogaster with Cryptococcus neoformans and role of the innate immune response.
Eukaryot Cell. 2004;3(2):413-9 - PMID: 15075271 - PMCID: PMC387633 - DOI: 10.1128/ec.3.2.413-419.2004

Mak HY, Ruvkun G

Intercellular signaling of reproductive development by the C. elegans DAF-9 cytochrome P450.
Development. 2004;131(8):1777-86 - PMID: 15084462 - DOI: 10.1242/dev.01069

Björkbacka H, Kunjathoor VV, Moore KJ, Koehn S, Ordija CM, Lee MA, Means T, Halmen K, Luster AD, Golenbock DT, Freeman MW

Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways.
Nat Med. 2004;10(4):416-21 - PMID: 15034566 - DOI: 10.1038/nm1008

Beck PL, Wong JF, Li Y, Swaminathan S, Xavier RJ, Devaney KL, Podolsky DK

Chemotherapy- and radiotherapy-induced intestinal damage is regulated by intestinal trefoil factor.
Gastroenterology. 2004;126(3):796-808 - PMID: 14988834 - DOI: 10.1053/j.gastro.2003.12.004

Thibodeau SA, Fang R, Joung JK

High-throughput beta-galactosidase assay for bacterial cell-based reporter systems.
Biotechniques. 2004;36(3):410-5 - PMID: 15038156 - DOI: 10.2144/04363BM07

Shou H, Bordallo P, Fan JB, Yeakley JM, Bibikova M, Sheen J, Wang K

Expression of an active tobacco mitogen-activated protein kinase kinase kinase enhances freezing tolerance in transgenic maize.
Proc Natl Acad Sci U S A. 2004;101(9):3298-303 - PMID: 14960727 - PMCID: PMC365784 - DOI: 10.1073/pnas.0308095100

Tewari M, Hu PJ, Ahn JS, Ayivi-Guedehoussou N, Vidalain PO, Li S, Milstein S, Armstrong CM, Boxem M, Butler MD, Busiguina S, Rual JF, Ibarrola N, Chaklos ST, Bertin N, Vaglio P, Edgley ML, King KV, Albert PS, Vandenhaute J, Pandey A, Riddle DL, Ruvkun G, Vidal M

Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network.
Mol Cell. 2004;13(4):469-82 - PMID: 14992718 - DOI: 10.1016/s1097-2765(04)00033-4

Kennedy S, Wang D, Ruvkun G

A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans.
Nature. 2004;427(6975):645-9 - PMID: 14961122 - DOI: 10.1038/nature02302

Chroni A, Liu T, Fitzgerald ML, Freeman MW, Zannis VI

Cross-linking and lipid efflux properties of apoA-I mutants suggest direct association between apoA-I helices and ABCA1.
Biochemistry. 2004;43(7):2126-39 - PMID: 14967052 - DOI: 10.1021/bi035813p

Shen Y, Jacobs JM, Camp DG, Fang R, Moore RJ, Smith RD, Xiao W, Davis RW, Tompkins RG

Ultra-high-efficiency strong cation exchange LC/RPLC/MS/MS for high dynamic range characterization of the human plasma proteome.
Anal Chem. 2004;76(4):1134-44 - PMID: 14961748 - DOI: 10.1021/ac034869m

Sheridan RL, Tompkins RG

What's new in burns and metabolism.
J Am Coll Surg. 2004;198(2):243-63 - PMID: 14759783 - DOI: 10.1016/j.jamcollsurg.2003.11.007

Mokuno Y, Berthiaume F, Tompkins RG, Balis UJ, Yarmush ML

Technique for expanding the donor liver pool: heat shock preconditioning in a rat fatty liver model.
Liver Transpl. 2004;10(2):264-72 - PMID: 14762865 - DOI: 10.1002/lt.20014

Déziel E, Lépine F, Milot S, He J, Mindrinos MN, Tompkins RG, Rahme LG

Analysis of Pseudomonas aeruginosa 4-hydroxy-2-alkylquinolines (HAQs) reveals a role for 4-hydroxy-2-heptylquinoline in cell-to-cell communication.
Proc Natl Acad Sci U S A. 2004;101(5):1339-44 - PMID: 14739337 - PMCID: PMC337054 - DOI: 10.1073/pnas.0307694100

Beck PL, Xavier R, Wong J, Ezedi I, Mashimo H, Mizoguchi A, Mizoguchi E, Bhan AK, Podolsky DK

Paradoxical roles of different nitric oxide synthase isoforms in colonic injury.
Am J Physiol Gastrointest Liver Physiol. 2004;286(1):G137-47 - PMID: 14665440 - DOI: 10.1152/ajpgi.00309.2003

Ruvkun G, Wightman B, Ha I

The 20 years it took to recognize the importance of tiny RNAs.
Cell. 2004;116(2 Suppl):S93-6, 2 p following S96 - PMID: 15055593 - DOI: 10.1016/s0092-8674(04)00034-0

Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G

Identification of many microRNAs that copurify with polyribosomes in mammalian neurons.
Proc Natl Acad Sci U S A. 2004;101(1):360-5 - PMID: 14691248 - PMCID: PMC314190 - DOI: 10.1073/pnas.2333854100

Luftig M, Yasui T, Soni V, Kang MS, Jacobson N, Cahir-McFarland E, Seed B, Kieff E

Epstein-Barr virus latent infection membrane protein 1 TRAF-binding site induces NIK/IKK alpha-dependent noncanonical NF-kappaB activation.
Proc Natl Acad Sci U S A. 2004;101(1):141-6 - PMID: 14691250 - PMCID: PMC314152 - DOI: 10.1073/pnas.2237183100

Thibodeau SA, Joung JK

An improved strategy for constructing "designer" Cys2His2 zinc finger proteins.
Discov Med. 2003;3(19):32-5 - PMID: 20705034

Komaroff AL, Ruvkun G

Unraveling the secrets of the cell.
Newsweek. 2003;142(23):96 - PMID: 14712576

Wang X, Seed B

A PCR primer bank for quantitative gene expression analysis.
Nucleic Acids Res. 2003;31(24):e154 - PMID: 14654707 - PMCID: PMC291882 - DOI: 10.1093/nar/gng154

Huang Z, Szostak JW

Evolution of aptamers with a new specificity and new secondary structures from an ATP aptamer.
RNA. 2003;9(12):1456-63 - PMID: 14624002 - PMCID: PMC1370500 - DOI: 10.1261/rna.5990203

Ishiguro K, Xavier R

Homer-3 regulates activation of serum response element in T cells via its EVH1 domain.
Blood. 2004;103(6):2248-56 - PMID: 14645007 - DOI: 10.1182/blood-2003-08-2671

Fitzgerald ML, Morris AL, Chroni A, Mendez AJ, Zannis VI, Freeman MW

ABCA1 and amphipathic apolipoproteins form high-affinity molecular complexes required for cholesterol efflux.
J Lipid Res. 2004;45(2):287-94 - PMID: 14617740 - DOI: 10.1194/jlr.M300355-JLR200
Total: 2489