Publications for All Faculty

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Duda DG, Fukumura D, Munn LL, Booth MF, Brown EB, Huang P, Seed B, Jain RK

Differential transplantability of tumor-associated stromal cells.
Cancer Res. 2004;64(17):5920-4 - PMID: 15342367 - DOI: 10.1158/0008-5472.CAN-04-1268

Austin CP, Battey JF, Bradley A, Bucan M, Capecchi M, Collins FS, Dove WF, Duyk G, Dymecki S, Eppig JT, Grieder FB, Heintz N, Hicks G, Insel TR, Joyner A, Koller BH, Lloyd KC, Magnuson T, Moore MW, Nagy A, Pollock JD, Roses AD, Sands AT, Seed B, Skarnes WC, Snoddy J, Soriano P, Stewart DJ, Stewart F, Stillman B, Varmus H, Varticovski L, Verma IM, Vogt TF, von Melchner H, Witkowski J, Woychik RP, Wurst W, Yancopoulos GD, Young SG, Zambrowicz B

The knockout mouse project.
Nat Genet. 2004;36(9):921-4 - PMID: 15340423 - PMCID: PMC2716027 - DOI: 10.1038/ng0904-921

Chen IA, Roberts RW, Szostak JW

The emergence of competition between model protocells.
Science. 2004;305(5689):1474-6 - PMID: 15353806 - PMCID: PMC4484590 - DOI: 10.1126/science.1100757

Jaffe JD, Stange-Thomann N, Smith C, DeCaprio D, Fisher S, Butler J, Calvo S, Elkins T, FitzGerald MG, Hafez N, Kodira CD, Major J, Wang S, Wilkinson J, Nicol R, Nusbaum C, Birren B, Berg HC, Church GM

The complete genome and proteome of Mycoplasma mobile.
Genome Res. 2004;14(8):1447-61 - PMID: 15289470 - PMCID: PMC509254 - DOI: 10.1101/gr.2674004

Chen IA, Szostak JW

A kinetic study of the growth of fatty acid vesicles.
Biophys J. 2004;87(2):988-98 - PMID: 15298905 - PMCID: PMC1304506 - DOI: 10.1529/biophysj.104.039875

Moy TI, Mylonakis E, Calderwood SB, Ausubel FM

Cytotoxicity of hydrogen peroxide produced by Enterococcus faecium.
Infect Immun. 2004;72(8):4512-20 - PMID: 15271910 - PMCID: PMC470665 - DOI: 10.1128/IAI.72.8.4512-4520.2004

Kim DH, Liberati NT, Mizuno T, Inoue H, Hisamoto N, Matsumoto K, Ausubel FM

Integration of Caenorhabditis elegans MAPK pathways mediating immunity and stress resistance by MEK-1 MAPK kinase and VHP-1 MAPK phosphatase.
Proc Natl Acad Sci U S A. 2004;101(30):10990-4 - PMID: 15256594 - PMCID: PMC503731 - DOI: 10.1073/pnas.0403546101

Xavier R, Rabizadeh S, Ishiguro K, Andre N, Ortiz JB, Wachtel H, Morris DG, Lopez-Ilasaca M, Shaw AC, Swat W, Seed B

Discs large (Dlg1) complexes in lymphocyte activation.
J Cell Biol. 2004;166(2):173-8 - PMID: 15263016 - PMCID: PMC2172307 - DOI: 10.1083/jcb.200309044

Sazani PL, Larralde R, Szostak JW

A small aptamer with strong and specific recognition of the triphosphate of ATP.
J Am Chem Soc. 2004;126(27):8370-1 - PMID: 15237981 - PMCID: PMC4983724 - DOI: 10.1021/ja049171k

Chaput JC, Szostak JW

Evolutionary optimization of a nonbiological ATP binding protein for improved folding stability.
Chem Biol. 2004;11(6):865-74 - PMID: 15217619 - DOI: 10.1016/j.chembiol.2004.04.006

Tenor JL, McCormick BA, Ausubel FM, Aballay A

Caenorhabditis elegans-based screen identifies Salmonella virulence factors required for conserved host-pathogen interactions.
Curr Biol. 2004;14(11):1018-24 - PMID: 15182677 - DOI: 10.1016/j.cub.2004.05.050

Engelbert M, Mylonakis E, Ausubel FM, Calderwood SB, Gilmore MS

Contribution of gelatinase, serine protease, and fsr to the pathogenesis of Enterococcus faecalis endophthalmitis.
Infect Immun. 2004;72(6):3628-33 - PMID: 15155673 - PMCID: PMC415677 - DOI: 10.1128/IAI.72.6.3628-3633.2004

Herndon DN, Tompkins RG

Support of the metabolic response to burn injury.
Lancet. 2004;363(9424):1895-902 - PMID: 15183630 - DOI: 10.1016/S0140-6736(04)16360-5

Sheridan RL, Prelack K, Yu YM, Lydon M, Petras L, Young VR, Tompkins RG

Short-term enteral glutamine does not enhance protein accretion in burned children: a stable isotope study.
Surgery. 2004;135(6):671-8 - PMID: 15179374 - DOI: 10.1016/j.surg.2003.11.014

Chen IA, Szostak JW

Membrane growth can generate a transmembrane pH gradient in fatty acid vesicles.
Proc Natl Acad Sci U S A. 2004;101(21):7965-70 - PMID: 15148394 - PMCID: PMC419540 - DOI: 10.1073/pnas.0308045101

Sugimachi K, Sosef MN, Baust JM, Fowler A, Tompkins RG, Toner M

Long-term function of cryopreserved rat hepatocytes in a coculture system.
Cell Transplant. 2004;13(2):187-95 - PMID: 15129765 - DOI: 10.3727/000000004773301799

Mizuno T, Hisamoto N, Terada T, Kondo T, Adachi M, Nishida E, Kim DH, Ausubel FM, Matsumoto K

The Caenorhabditis elegans MAPK phosphatase VHP-1 mediates a novel JNK-like signaling pathway in stress response.
EMBO J. 2004;23(11):2226-34 - PMID: 15116070 - PMCID: PMC419906 - DOI: 10.1038/sj.emboj.7600226

Rabizadeh S, Xavier RJ, Ishiguro K, Bernabeortiz J, Lopez-Ilasaca M, Khokhlatchev A, Mollahan P, Pfeifer GP, Avruch J, Seed B

The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death.
J Biol Chem. 2004;279(28):29247-54 - PMID: 15075335 - DOI: 10.1074/jbc.M401699200

Liberati NT, Fitzgerald KA, Kim DH, Feinbaum R, Golenbock DT, Ausubel FM

Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response.
Proc Natl Acad Sci U S A. 2004;101(17):6593-8 - PMID: 15123841 - PMCID: PMC404090 - DOI: 10.1073/pnas.0308625101

Nguyen-Hackley DH, Ramm E, Taylor CM, Joung JK, Dervan PB, Pabo CO

Allosteric inhibition of zinc-finger binding in the major groove of DNA by minor-groove binding ligands.
Biochemistry. 2004;43(13):3880-90 - PMID: 15049695 - DOI: 10.1021/bi030223c

Carothers JM, Oestreich SC, Davis JH, Szostak JW

Informational complexity and functional activity of RNA structures.
J Am Chem Soc. 2004;126(16):5130-7 - PMID: 15099096 - PMCID: PMC5042360 - DOI: 10.1021/ja031504a

Apidianakis Y, Rahme LG, Heitman J, Ausubel FM, Calderwood SB, Mylonakis E

Challenge of Drosophila melanogaster with Cryptococcus neoformans and role of the innate immune response.
Eukaryot Cell. 2004;3(2):413-9 - PMID: 15075271 - PMCID: PMC387633 - DOI: 10.1128/ec.3.2.413-419.2004

Mak HY, Ruvkun G

Intercellular signaling of reproductive development by the C. elegans DAF-9 cytochrome P450.
Development. 2004;131(8):1777-86 - PMID: 15084462 - DOI: 10.1242/dev.01069

Björkbacka H, Kunjathoor VV, Moore KJ, Koehn S, Ordija CM, Lee MA, Means T, Halmen K, Luster AD, Golenbock DT, Freeman MW

Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways.
Nat Med. 2004;10(4):416-21 - PMID: 15034566 - DOI: 10.1038/nm1008

Beck PL, Wong JF, Li Y, Swaminathan S, Xavier RJ, Devaney KL, Podolsky DK

Chemotherapy- and radiotherapy-induced intestinal damage is regulated by intestinal trefoil factor.
Gastroenterology. 2004;126(3):796-808 - PMID: 14988834 - DOI: 10.1053/j.gastro.2003.12.004
Total: 2483