Publications for All Faculty

Sort by:
Hanczyc MM, Szostak JW

Replicating vesicles as models of primitive cell growth and division.

Curr Opin Chem Biol. 2004;8(6):660-4 - PMID: 15556412 - DOI: 10.1016/j.cbpa.2004.10.002
Kim WS, Fitzgerald ML, Kang K, Okuhira K, Bell SA, Manning JJ, Koehn SL, Lu N, Moore KJ, Freeman MW

Abca7 null mice retain normal macrophage phosphatidylcholine and cholesterol efflux activity despite alterations in adipose mass and serum cholesterol levels.

J Biol Chem. 2005;280(5):3989-95 - PMID: 15550377 - DOI: 10.1074/jbc.M412602200
Sethu P, Anahtar M, Moldawer LL, Tompkins RG, Toner M

Continuous flow microfluidic device for rapid erythrocyte lysis.

Anal Chem. 2004;76(21):6247-53 - PMID: 15516115 - DOI: 10.1021/ac049429p
Feezor RJ, Baker HV, Mindrinos M, Hayden D, Tannahill CL, Brownstein BH, Fay A, MacMillan S, Laramie J, Xiao W, Moldawer LL, Cobb JP, Laudanski K, Miller-Graziano CL, Maier RV, Schoenfeld D, Davis RW, Tompkins RG,

Whole blood and leukocyte RNA isolation for gene expression analyses.

Physiol Genomics. 2004;19(3):247-54 - PMID: 15548831 - DOI: 10.1152/physiolgenomics.00020.2004
Garsin DA, Urbach J, Huguet-Tapia JC, Peters JE, Ausubel FM

Construction of an Enterococcus faecalis Tn917-mediated-gene-disruption library offers insight into Tn917 insertion patterns.

J Bacteriol. 2004;186(21):7280-9 - PMID: 15489440 - PMCID: PMC523214 - DOI: 10.1128/JB.186.21.7280-7289.2004
Ricci R, Sumara G, Sumara I, Rozenberg I, Kurrer M, Akhmedov A, Hersberger M, Eriksson U, Eberli FR, Becher B, Borén J, Chen M, Cybulsky MI, Moore KJ, Freeman MW, Wagner EF, Matter CM, Lüscher TF

Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis.

Science. 2004;306(5701):1558-61 - PMID: 15567863 - DOI: 10.1126/science.1101909
Rojo E, Martín R, Carter C, Zouhar J, Pan S, Plotnikova J, Jin H, Paneque M, Sánchez-Serrano JJ, Baker B, Ausubel FM, Raikhel NV

VPEgamma exhibits a caspase-like activity that contributes to defense against pathogens.

Curr Biol. 2004;14(21):1897-906 - PMID: 15530390 - DOI: 10.1016/j.cub.2004.09.056
Revzin A, Sekine K, Sin A, Tompkins RG, Toner M

Development of a microfabricated cytometry platform for characterization and sorting of individual leukocytes.

Lab Chip. 2005;5(1):30-7 - PMID: 15616737 - DOI: 10.1039/b405557h
Irimia D, Tompkins RG, Toner M

Single-cell chemical lysis in picoliter-scale closed volumes using a microfabricated device.

Anal Chem. 2004;76(20):6137-43 - PMID: 15481964 - DOI: 10.1021/ac0497508
Mylonakis E, Idnurm A, Moreno R, El Khoury J, Rottman JB, Ausubel FM, Heitman J, Calderwood SB

Cryptococcus neoformans Kin1 protein kinase homologue, identified through a Caenorhabditis elegans screen, promotes virulence in mammals.

Mol Microbiol. 2004;54(2):407-19 - PMID: 15469513 - DOI: 10.1111/j.1365-2958.2004.04310.x
Carter EA, Burks D, Fischman AJ, White M, Tompkins RG

Insulin resistance in thermally-injured rats is associated with post-receptor alterations in skeletal muscle, liver and adipose tissue.

Int J Mol Med. 2004;14(4):653-8 - PMID: 15375597
Jaillon O, Aury JM, Brunet F, Petit JL, Stange-Thomann N, Mauceli E, Bouneau L, Fischer C, Ozouf-Costaz C, Bernot A, Nicaud S, Jaffe D, Fisher S, Lutfalla G, Dossat C, Segurens B, Dasilva C, Salanoubat M, Levy M, Boudet N, Castellano S, Anthouard V, Jubin C, Castelli V, Katinka M, Vacherie B, Biémont C, Skalli Z, Cattolico L, Poulain J, De Berardinis V, Cruaud C, Duprat S, Brottier P, Coutanceau JP, Gouzy J, Parra G, Lardier G, Chapple C, McKernan KJ, McEwan P, Bosak S, Kellis M, Volff JN, Guigó R, Zody MC, Mesirov J, Lindblad-Toh K, Birren B, Nusbaum C, Kahn D, Robinson-Rechavi M, Laudet V, Schachter V, Quétier F, Saurin W, Scarpelli C, Wincker P, Lander ES, Weissenbach J, Roest Crollius H

Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype.

Nature. 2004;431(7011):946-57 - PMID: 15496914 - DOI: 10.1038/nature03025
Björkbacka H, Fitzgerald KA, Huet F, Li X, Gregory JA, Lee MA, Ordija CM, Dowley NE, Golenbock DT, Freeman MW

The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades.

Physiol Genomics. 2004;19(3):319-30 - PMID: 15367722 - DOI: 10.1152/physiolgenomics.00128.2004
Mansfield JH, Harfe BD, Nissen R, Obenauer J, Srineel J, Chaudhuri A, Farzan-Kashani R, Zuker M, Pasquinelli AE, Ruvkun G, Sharp PA, Tabin CJ, McManus MT

MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression.

Nat Genet. 2004;36(10):1079-83 - PMID: 15361871 - DOI: 10.1038/ng1421
Fitzgerald ML, Okuhira K, Short GF, Manning JJ, Bell SA, Freeman MW

ATP-binding cassette transporter A1 contains a novel C-terminal VFVNFA motif that is required for its cholesterol efflux and ApoA-I binding activities.

J Biol Chem. 2004;279(46):48477-85 - PMID: 15347662 - DOI: 10.1074/jbc.M409848200
Duda DG, Fukumura D, Munn LL, Booth MF, Brown EB, Huang P, Seed B, Jain RK

Differential transplantability of tumor-associated stromal cells.

Cancer Res. 2004;64(17):5920-4 - PMID: 15342367 - DOI: 10.1158/0008-5472.CAN-04-1268
Austin CP, Battey JF, Bradley A, Bucan M, Capecchi M, Collins FS, Dove WF, Duyk G, Dymecki S, Eppig JT, Grieder FB, Heintz N, Hicks G, Insel TR, Joyner A, Koller BH, Lloyd KC, Magnuson T, Moore MW, Nagy A, Pollock JD, Roses AD, Sands AT, Seed B, Skarnes WC, Snoddy J, Soriano P, Stewart DJ, Stewart F, Stillman B, Varmus H, Varticovski L, Verma IM, Vogt TF, von Melchner H, Witkowski J, Woychik RP, Wurst W, Yancopoulos GD, Young SG, Zambrowicz B

The knockout mouse project.

Nat Genet. 2004;36(9):921-4 - PMID: 15340423 - PMCID: PMC2716027 - DOI: 10.1038/ng0904-921
Chen IA, Roberts RW, Szostak JW

The emergence of competition between model protocells.

Science. 2004;305(5689):1474-6 - PMID: 15353806 - PMCID: PMC4484590 - DOI: 10.1126/science.1100757
Jaffe JD, Stange-Thomann N, Smith C, DeCaprio D, Fisher S, Butler J, Calvo S, Elkins T, FitzGerald MG, Hafez N, Kodira CD, Major J, Wang S, Wilkinson J, Nicol R, Nusbaum C, Birren B, Berg HC, Church GM

The complete genome and proteome of Mycoplasma mobile.

Genome Res. 2004;14(8):1447-61 - PMID: 15289470 - PMCID: PMC509254 - DOI: 10.1101/gr.2674004
Moy TI, Mylonakis E, Calderwood SB, Ausubel FM

Cytotoxicity of hydrogen peroxide produced by Enterococcus faecium.

Infect Immun. 2004;72(8):4512-20 - PMID: 15271910 - PMCID: PMC470665 - DOI: 10.1128/IAI.72.8.4512-4520.2004
Chen IA, Szostak JW

A kinetic study of the growth of fatty acid vesicles.

Biophys J. 2004;87(2):988-98 - PMID: 15298905 - PMCID: PMC1304506 - DOI: 10.1529/biophysj.104.039875
Kim DH, Liberati NT, Mizuno T, Inoue H, Hisamoto N, Matsumoto K, Ausubel FM

Integration of Caenorhabditis elegans MAPK pathways mediating immunity and stress resistance by MEK-1 MAPK kinase and VHP-1 MAPK phosphatase.

Proc Natl Acad Sci U S A. 2004;101(30):10990-4 - PMID: 15256594 - PMCID: PMC503731 - DOI: 10.1073/pnas.0403546101
Xavier R, Rabizadeh S, Ishiguro K, Andre N, Ortiz JB, Wachtel H, Morris DG, Lopez-Ilasaca M, Shaw AC, Swat W, Seed B

Discs large (Dlg1) complexes in lymphocyte activation.

J Cell Biol. 2004;166(2):173-8 - PMID: 15263016 - PMCID: PMC2172307 - DOI: 10.1083/jcb.200309044
Sazani PL, Larralde R, Szostak JW

A small aptamer with strong and specific recognition of the triphosphate of ATP.

J Am Chem Soc. 2004;126(27):8370-1 - PMID: 15237981 - PMCID: PMC4983724 - DOI: 10.1021/ja049171k
Herndon DN, Tompkins RG

Support of the metabolic response to burn injury.

Lancet. 2004;363(9424):1895-902 - PMID: 15183630 - DOI: 10.1016/S0140-6736(04)16360-5
Total: 2473