Publications for All Faculty

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Wang D, Ruvkun G

Regulation of Caenorhabditis elegans RNA interference by the daf-2 insulin stress and longevity signaling pathway.
Cold Spring Harb Symp Quant Biol. 2005;69:429-31 - PMID: 16117677 - DOI: 10.1101/sqb.2004.69.429

Lee ML, Whitmore GA, Björkbacka H, Freeman MW

Nonparametric methods for microarray data based on exchangeability and borrowed power.
J Biopharm Stat. 2005;15(5):783-97 - PMID: 16078385 - DOI: 10.1081/BIP-200067778

Vinson JP, Jaffe DB, O'Neill K, Karlsson EK, Stange-Thomann N, Anderson S, Mesirov JP, Satoh N, Satou Y, Nusbaum C, Birren B, Galagan JE, Lander ES

Assembly of polymorphic genomes: algorithms and application to Ciona savignyi.
Genome Res. 2005;15(8):1127-35 - PMID: 16077012 - PMCID: PMC1182225 - DOI: 10.1101/gr.3722605

Moore KJ, Kunjathoor VV, Koehn SL, Manning JJ, Tseng AA, Silver JM, McKee M, Freeman MW

Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice.
J Clin Invest. 2005;115(8):2192-201 - PMID: 16075060 - PMCID: PMC1180534 - DOI: 10.1172/JCI24061

Stuart LM, Deng J, Silver JM, Takahashi K, Tseng AA, Hennessy EJ, Ezekowitz RA, Moore KJ

Response to Staphylococcus aureus requires CD36-mediated phagocytosis triggered by the COOH-terminal cytoplasmic domain.
J Cell Biol. 2005;170(3):477-85 - PMID: 16061696 - PMCID: PMC2171464 - DOI: 10.1083/jcb.200501113

Josephson K, Hartman MC, Szostak JW

Ribosomal synthesis of unnatural peptides.
J Am Chem Soc. 2005;127(33):11727-35 - PMID: 16104750 - DOI: 10.1021/ja0515809

Vallet-Gely I, Donovan KE, Fang R, Joung JK, Dove SL

Repression of phase-variable cup gene expression by H-NS-like proteins in Pseudomonas aeruginosa.
Proc Natl Acad Sci U S A. 2005;102(31):11082-7 - PMID: 16043713 - PMCID: PMC1182424 - DOI: 10.1073/pnas.0502663102

Laberge MA, Moore KJ, Freeman MW

Atherosclerosis and innate immune signaling.
Ann Med. 2005;37(2):130-40 - PMID: 16026120 - DOI: 10.1080/07853890510007304

Ting A, Lichtenthaler S, Xavier R, Na SY, Rabizadeh S, Holmes T, Seed B

Large-scale screens for cDNAs with in vivo activity.
Novartis Found Symp. 2005;267:219-29; discussion 229-30 - PMID: 15999809

Barnich N, Aguirre JE, Reinecker HC, Xavier R, Podolsky DK

Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognition.
J Cell Biol. 2005;170(1):21-6 - PMID: 15998797 - PMCID: PMC2171381 - DOI: 10.1083/jcb.200502153

Wang D, Kennedy S, Conte D, Kim JK, Gabel HW, Kamath RS, Mello CC, Ruvkun G

Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants.
Nature. 2005;436(7050):593-7 - PMID: 16049496 - DOI: 10.1038/nature04010

Sieburth D, Ch'ng Q, Dybbs M, Tavazoie M, Kennedy S, Wang D, Dupuy D, Rual JF, Hill DE, Vidal M, Ruvkun G, Kaplan JM

Systematic analysis of genes required for synapse structure and function.
Nature. 2005;436(7050):510-7 - PMID: 16049479 - DOI: 10.1038/nature03809

Hamilton B, Dong Y, Shindo M, Liu W, Odell I, Ruvkun G, Lee SS

A systematic RNAi screen for longevity genes in C. elegans.
Genes Dev. 2005;19(13):1544-55 - PMID: 15998808 - PMCID: PMC1172061 - DOI: 10.1101/gad.1308205

Heller EA, Liu E, Tager AM, Sinha S, Roberts JD, Koehn SL, Libby P, Aikawa ER, Chen JQ, Huang P, Freeman MW, Moore KJ, Luster AD, Gerszten RE

Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment.
Circulation. 2005;112(4):578-86 - PMID: 16043658 - DOI: 10.1161/CIRCULATIONAHA.105.545616

Mylonakis E, Moreno R, El Khoury JB, Idnurm A, Heitman J, Calderwood SB, Ausubel FM, Diener A

Galleria mellonella as a model system to study Cryptococcus neoformans pathogenesis.
Infect Immun. 2005;73(7):3842-50 - PMID: 15972469 - PMCID: PMC1168598 - DOI: 10.1128/IAI.73.7.3842-3850.2005

Ruvkun GB

The tiny RNA world.
Harvey Lect. 2005;99:1-21 - PMID: 15984549

Zhang Q, Carter EA, Ma BY, White M, Fischman AJ, Tompkins RG

Molecular mechanism(s) of burn-induced insulin resistance in murine skeletal muscle: role of IRS phosphorylation.
Life Sci. 2005;77(24):3068-77 - PMID: 15982669 - DOI: 10.1016/j.lfs.2005.02.034

Diener AC, Ausubel FM

RESISTANCE TO FUSARIUM OXYSPORUM 1, a dominant Arabidopsis disease-resistance gene, is not race specific.
Genetics. 2005;171(1):305-21 - PMID: 15965251 - PMCID: PMC1456520 - DOI: 10.1534/genetics.105.042218

Iwasaki H, Mizuno S, Mayfield R, Shigematsu H, Arinobu Y, Seed B, Gurish MF, Takatsu K, Akashi K

Identification of eosinophil lineage-committed progenitors in the murine bone marrow.
J Exp Med. 2005;201(12):1891-7 - PMID: 15955840 - PMCID: PMC2212039 - DOI: 10.1084/jem.20050548

Xavier R, Seed B

PDZ domains and the politics of polarity in lymphocytes.
Immunity. 2005;22(6):655-6 - PMID: 15963778 - DOI: 10.1016/j.immuni.2005.06.003

Stuart LM, Ezekowitz RA

Phagocytosis: elegant complexity.
Immunity. 2005;22(5):539-50 - PMID: 15894272 - DOI: 10.1016/j.immuni.2005.05.002

Horhota A, Zou K, Ichida JK, Yu B, McLaughlin LW, Szostak JW, Chaput JC

Kinetic analysis of an efficient DNA-dependent TNA polymerase.
J Am Chem Soc. 2005;127(20):7427-34 - PMID: 15898792 - PMCID: PMC5042361 - DOI: 10.1021/ja0428255

Lu XM, Lu MY, Fischman AJ, Tompkins RG

A new approach for sequencing human IRS1 phosphotyrosine-containing peptides using CapLC-Q-TOF(micro).
J Mass Spectrom. 2005;40(5):599-607 - PMID: 15739155 - DOI: 10.1002/jms.826

Shen X, Valencia CA, Szostak JW, Szostak J, Dong B, Liu R

Scanning the human proteome for calmodulin-binding proteins.
Proc Natl Acad Sci U S A. 2005;102(17):5969-74 - PMID: 15840729 - PMCID: PMC1087907 - DOI: 10.1073/pnas.0407928102

Sacerdote MG, Szostak JW

Semipermeable lipid bilayers exhibit diastereoselectivity favoring ribose.
Proc Natl Acad Sci U S A. 2005;102(17):6004-8 - PMID: 15831588 - PMCID: PMC556129 - DOI: 10.1073/pnas.0408440102
Total: 2501