Publications for All Faculty

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Plummer KA, Carothers JM, Yoshimura M, Szostak JW, Verdine GL

In vitro selection of RNA aptamers against a composite small molecule-protein surface.

Nucleic Acids Res. 2005;33(17):5602-10 - PMID: 16199752 - PMCID: PMC1240114 - DOI: 10.1093/nar/gki867
Okuhira K, Fitzgerald ML, Sarracino DA, Manning JJ, Bell SA, Goss JL, Freeman MW

Purification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol efflux.

J Biol Chem. 2005;280(47):39653-64 - PMID: 16192269 - DOI: 10.1074/jbc.M510187200
Ichida JK, Horhota A, Zou K, McLaughlin LW, Szostak JW

High fidelity TNA synthesis by Therminator polymerase.

Nucleic Acids Res. 2005;33(16):5219-25 - PMID: 16157867 - PMCID: PMC1214552 - DOI: 10.1093/nar/gki840
Storey JD, Xiao W, Leek JT, Tompkins RG, Davis RW

Significance analysis of time course microarray experiments.

Proc Natl Acad Sci U S A. 2005;102(36):12837-42 - PMID: 16141318 - PMCID: PMC1201697 - DOI: 10.1073/pnas.0504609102
Sin A, Murthy SK, Revzin A, Tompkins RG, Toner M

Enrichment using antibody-coated microfluidic chambers in shear flow: model mixtures of human lymphocytes.

Biotechnol Bioeng. 2005;91(7):816-26 - PMID: 16037988 - DOI: 10.1002/bit.20556
Astrakas LG, Goljer I, Yasuhara S, Padfield KE, Zhang Q, Gopalan S, Mindrinos MN, Dai G, Yu YM, Martyn JA, Tompkins RG, Rahme LG, Tzika AA

Proton NMR spectroscopy shows lipids accumulate in skeletal muscle in response to burn trauma-induced apoptosis.

FASEB J. 2005;19(11):1431-40 - PMID: 16126910 - DOI: 10.1096/fj.04-2005com
Chen IA, Salehi-Ashtiani K, Szostak JW

RNA catalysis in model protocell vesicles.

J Am Chem Soc. 2005;127(38):13213-9 - PMID: 16173749 - PMCID: PMC5072289 - DOI: 10.1021/ja051784p
M Freeman, Consultant editor 3rd edition Junge C, Skerret PJ, and Emond, SD.

What to do about high cholesterol

President and Fellows of Harvard College. Harvard Health Publications. 2005;:ePub
MW Freeman

Approach to the patient with hypercholesterolemia. In: Goroll A, May L, Mulley A, eds

Primary Care Medicine, 5th Edition. 2005;:ePub
Lu XM, Lu M, Tompkins RG, Fischman AJ

Site-specific detection of S-nitrosylated PKB alpha/Akt1 from rat soleus muscle using CapLC-Q-TOF(micro) mass spectrometry.

J Mass Spectrom. 2005;40(9):1140-8 - PMID: 16041729 - DOI: 10.1002/jms.885
Gilmore O’Neill and MW Freeman

Tangier Disease and Neuropathy. In: Dyck, PJ and Thomas, PK, Eds

Peripheral Neuropathy 4th edition. 2005;:ePub
Laberge MA, Moore KJ, and MW Freeman.

Atherosclerosis and innate immunity signaling

Annals of Medicine. 2005;37:130-140
Yang M, Hase H, Legarda-Addison D, Varughese L, Seed B, Ting AT

B cell maturation antigen, the receptor for a proliferation-inducing ligand and B cell-activating factor of the TNF family, induces antigen presentation in B cells.

J Immunol. 2005;175(5):2814-24 - PMID: 16116167 - DOI: 10.4049/jimmunol.175.5.2814
Calvano SE, Xiao W, Richards DR, Felciano RM, Baker HV, Cho RJ, Chen RO, Brownstein BH, Cobb JP, Tschoeke SK, Miller-Graziano C, Moldawer LL, Mindrinos MN, Davis RW, Tompkins RG, Lowry SF,

A network-based analysis of systemic inflammation in humans.

Nature. 2005;437(7061):1032-7 - PMID: 16136080 - DOI: 10.1038/nature03985
Frand AR, Russel S, Ruvkun G

Functional genomic analysis of C. elegans molting.

PLoS Biol. 2005;3(10):e312 - PMID: 16122351 - PMCID: PMC1233573 - DOI: 10.1371/journal.pbio.0030312
Wang D, Ruvkun G

Regulation of Caenorhabditis elegans RNA interference by the daf-2 insulin stress and longevity signaling pathway.

Cold Spring Harb Symp Quant Biol. 2005;69:429-31 - PMID: 16117677 - DOI: 10.1101/sqb.2004.69.429
Lee ML, Whitmore GA, Björkbacka H, Freeman MW

Nonparametric methods for microarray data based on exchangeability and borrowed power.

J Biopharm Stat. 2005;15(5):783-97 - PMID: 16078385 - DOI: 10.1081/BIP-200067778
Vinson JP, Jaffe DB, O'Neill K, Karlsson EK, Stange-Thomann N, Anderson S, Mesirov JP, Satoh N, Satou Y, Nusbaum C, Birren B, Galagan JE, Lander ES

Assembly of polymorphic genomes: algorithms and application to Ciona savignyi.

Genome Res. 2005;15(8):1127-35 - PMID: 16077012 - PMCID: PMC1182225 - DOI: 10.1101/gr.3722605
Stuart LM, Deng J, Silver JM, Takahashi K, Tseng AA, Hennessy EJ, Ezekowitz RA, Moore KJ

Response to Staphylococcus aureus requires CD36-mediated phagocytosis triggered by the COOH-terminal cytoplasmic domain.

J Cell Biol. 2005;170(3):477-85 - PMID: 16061696 - PMCID: PMC2171464 - DOI: 10.1083/jcb.200501113
Moore KJ, Kunjathoor VV, Koehn SL, Manning JJ, Tseng AA, Silver JM, McKee M, Freeman MW

Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice.

J Clin Invest. 2005;115(8):2192-201 - PMID: 16075060 - PMCID: PMC1180534 - DOI: 10.1172/JCI24061
Josephson K, Hartman MC, Szostak JW

Ribosomal synthesis of unnatural peptides.

J Am Chem Soc. 2005;127(33):11727-35 - PMID: 16104750 - DOI: 10.1021/ja0515809
Vallet-Gely I, Donovan KE, Fang R, Joung JK, Dove SL

Repression of phase-variable cup gene expression by H-NS-like proteins in Pseudomonas aeruginosa.

Proc Natl Acad Sci U S A. 2005;102(31):11082-7 - PMID: 16043713 - PMCID: PMC1182424 - DOI: 10.1073/pnas.0502663102
Laberge MA, Moore KJ, Freeman MW

Atherosclerosis and innate immune signaling.

Ann Med. 2005;37(2):130-40 - PMID: 16026120 - DOI: 10.1080/07853890510007304
Ting A, Lichtenthaler S, Xavier R, Na SY, Rabizadeh S, Holmes T, Seed B

Large-scale screens for cDNAs with in vivo activity.

Novartis Found Symp. 2005;267:219-29; discussion 229-30 - PMID: 15999809
Wang D, Kennedy S, Conte D, Kim JK, Gabel HW, Kamath RS, Mello CC, Ruvkun G

Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants.

Nature. 2005;436(7050):593-7 - PMID: 16049496 - DOI: 10.1038/nature04010
Total: 2466