Publications for All Faculty

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Sugimachi K, Roach KL, Rhoads DB, Tompkins RG, Toner M

Nonmetabolizable glucose compounds impart cryotolerance to primary rat hepatocytes.
Tissue Eng. 2006;12(3):579-88 - PMID: 16579691 - DOI: 10.1089/ten.2006.12.579

Carothers JM, Davis JH, Chou JJ, Szostak JW

Solution structure of an informationally complex high-affinity RNA aptamer to GTP.
RNA. 2006;12(4):567-79 - PMID: 16510427 - PMCID: PMC1421093 - DOI: 10.1261/rna.2251306

Kulasakara H, Lee V, Brencic A, Liberati N, Urbach J, Miyata S, Lee DG, Neely AN, Hyodo M, Hayakawa Y, Ausubel FM, Lory S

Analysis of Pseudomonas aeruginosa diguanylate cyclases and phosphodiesterases reveals a role for bis-(3'-5')-cyclic-GMP in virulence.
Proc Natl Acad Sci U S A. 2006;103(8):2839-44 - PMID: 16477007 - PMCID: PMC1413825 - DOI: 10.1073/pnas.0511090103

Liberati NT, Urbach JM, Miyata S, Lee DG, Drenkard E, Wu G, Villanueva J, Wei T, Ausubel FM

An ordered, nonredundant library of Pseudomonas aeruginosa strain PA14 transposon insertion mutants.
Proc Natl Acad Sci U S A. 2006;103(8):2833-8 - PMID: 16477005 - PMCID: PMC1413827 - DOI: 10.1073/pnas.0511100103

Mak HY, Nelson LS, Basson M, Johnson CD, Ruvkun G

Polygenic control of Caenorhabditis elegans fat storage.
Nat Genet. 2006;38(3):363-8 - PMID: 16462744 - DOI: 10.1038/ng1739

Meng X, Smith RM, Giesecke AV, Joung JK, Wolfe SA

Counter-selectable marker for bacterial-based interaction trap systems.
Biotechniques. 2006;40(2):179-84 - PMID: 16526407 - DOI: 10.2144/000112049

Cho GS, Szostak JW

Directed evolution of ATP binding proteins from a zinc finger domain by using mRNA display.
Chem Biol. 2006;13(2):139-47 - PMID: 16492562 - DOI: 10.1016/j.chembiol.2005.10.015

Freeman MW

Statins, cholesterol, and the prevention of coronary heart disease.
FASEB J. 2006;20(2):200-1 - PMID: 16449790 - DOI: 10.1096/fj.06-0202ufm

Schöbel S, Neumann S, Seed B, Lichtenthaler SF

Expression cloning screen for modifiers of amyloid precursor protein shedding.
Int J Dev Neurosci. 2006;24(2-3):141-8 - PMID: 16446073 - DOI: 10.1016/j.ijdevneu.2005.11.003

Stuart LM, Henson PM, Vandivier RW

Collectins: opsonins for apoptotic cells and regulators of inflammation.
Curr Dir Autoimmun. 2006;9:143-61 - PMID: 16394659 - DOI: 10.1159/000090778

Duchaine TF, Wohlschlegel JA, Kennedy S, Bei Y, Conte D, Pang K, Brownell DR, Harding S, Mitani S, Ruvkun G, Yates JR, Mello CC

Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways.
Cell. 2006;124(2):343-54 - PMID: 16439208 - DOI: 10.1016/j.cell.2005.11.036

Ruvkun G

Clarifications on miRNA and cancer.
Science. 2006;311(5757):36-7 - PMID: 16400132 - DOI: 10.1126/science.311.5757.36d

Hung DT, Zhu J, Sturtevant D, Mekalanos JJ

Bile acids stimulate biofilm formation in Vibrio cholerae.
Mol Microbiol. 2006;59(1):193-201 - PMID: 16359328 - DOI: 10.1111/j.1365-2958.2005.04846.x

Lindblad-Toh K, Wade CM, Mikkelsen TS, Karlsson EK, Jaffe DB, Kamal M, Clamp M, Chang JL, Kulbokas EJ, Zody MC, Mauceli E, Xie X, Breen M, Wayne RK, Ostrander EA, Ponting CP, Galibert F, Smith DR, DeJong PJ, Kirkness E, Alvarez P, Biagi T, Brockman W, Butler J, Chin CW, Cook A, Cuff J, Daly MJ, DeCaprio D, Gnerre S, Grabherr M, Kellis M, Kleber M, Bardeleben C, Goodstadt L, Heger A, Hitte C, Kim L, Koepfli KP, Parker HG, Pollinger JP, Searle SM, Sutter NB, Thomas R, Webber C, Baldwin J, Abebe A, Abouelleil A, Aftuck L, Ait-Zahra M, Aldredge T, Allen N, An P, Anderson S, Antoine C, Arachchi H, Aslam A, Ayotte L, Bachantsang P, Barry A, Bayul T, Benamara M, Berlin A, Bessette D, Blitshteyn B, Bloom T, Blye J, Boguslavskiy L, Bonnet C, Boukhgalter B, Brown A, Cahill P, Calixte N, Camarata J, Cheshatsang Y, Chu J, Citroen M, Collymore A, Cooke P, Dawoe T, Daza R, Decktor K, DeGray S, Dhargay N, Dooley K, Dooley K, Dorje P, Dorjee K, Dorris L, Duffey N, Dupes A, Egbiremolen O, Elong R, Falk J, Farina A, Faro S, Ferguson D, Ferreira P, Fisher S, FitzGerald M, Foley K, Foley C, Franke A, Friedrich D, Gage D, Garber M, Gearin G, Giannoukos G, Goode T, Goyette A, Graham J, Grandbois E, Gyaltsen K, Hafez N, Hagopian D, Hagos B, Hall J, Healy C, Hegarty R, Honan T, Horn A, Houde N, Hughes L, Hunnicutt L, Husby M, Jester B, Jones C, Kamat A, Kanga B, Kells C, Khazanovich D, Kieu AC, Kisner P, Kumar M, Lance K, Landers T, Lara M, Lee W, Leger JP, Lennon N, Leuper L, LeVine S, Liu J, Liu X, Lokyitsang Y, Lokyitsang T, Lui A, Macdonald J, Major J, Marabella R, Maru K, Matthews C, McDonough S, Mehta T, Meldrim J, Melnikov A, Meneus L, Mihalev A, Mihova T, Miller K, Mittelman R, Mlenga V, Mulrain L, Munson G, Navidi A, Naylor J, Nguyen T, Nguyen N, Nguyen C, Nguyen T, Nicol R, Norbu N, Norbu C, Novod N, Nyima T, Olandt P, O'Neill B, O'Neill K, Osman S, Oyono L, Patti C, Perrin D, Phunkhang P, Pierre F, Priest M, Rachupka A, Raghuraman S, Rameau R, Ray V, Raymond C, Rege F, Rise C, Rogers J, Rogov P, Sahalie J, Settipalli S, Sharpe T, Shea T, Sheehan M, Sherpa N, Shi J, Shih D, Sloan J, Smith C, Sparrow T, Stalker J, Stange-Thomann N, Stavropoulos S, Stone C, Stone S, Sykes S, Tchuinga P, Tenzing P, Tesfaye S, Thoulutsang D, Thoulutsang Y, Topham K, Topping I, Tsamla T, Vassiliev H, Venkataraman V, Vo A, Wangchuk T, Wangdi T, Weiand M, Wilkinson J, Wilson A, Yadav S, Yang S, Yang X, Young G, Yu Q, Zainoun J, Zembek L, Zimmer A, Lander ES

Genome sequence, comparative analysis and haplotype structure of the domestic dog.
Nature. 2005;438(7069):803-19 - PMID: 16341006 - DOI: 10.1038/nature04338

Fujikawa SM, Chen IA, Szostak JW

Shrink-wrap vesicles.
Langmuir. 2005;21(26):12124-9 - PMID: 16342983 - PMCID: PMC2548281 - DOI: 10.1021/la052590q

De AK, Miller-Graziano CL, Calvano SE, Laudanski K, Lowry SF, Moldawer LL, Remick DG, Rajicic N, Schoenfeld D, Tompkins RG

Selective activation of peripheral blood T cell subsets by endotoxin infusion in healthy human subjects corresponds to differential chemokine activation.
J Immunol. 2005;175(9):6155-62 - PMID: 16237112 - DOI: 10.4049/jimmunol.175.9.6155

Hung DT, Shakhnovich EA, Pierson E, Mekalanos JJ

Small-molecule inhibitor of Vibrio cholerae virulence and intestinal colonization.
Science. 2005;310(5748):670-4 - PMID: 16223984 - DOI: 10.1126/science.1116739

Kocks C, Cho JH, Nehme N, Ulvila J, Pearson AM, Meister M, Strom C, Conto SL, Hetru C, Stuart LM, Stehle T, Hoffmann JA, Reichhart JM, Ferrandon D, Rämet M, Ezekowitz RA

Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila.
Cell. 2005;123(2):335-46 - PMID: 16239149 - DOI: 10.1016/j.cell.2005.08.034

Ausubel FM

Are innate immune signaling pathways in plants and animals conserved?
Nat Immunol. 2005;6(10):973-9 - PMID: 16177805 - DOI: 10.1038/ni1253

Plummer KA, Carothers JM, Yoshimura M, Szostak JW, Verdine GL

In vitro selection of RNA aptamers against a composite small molecule-protein surface.
Nucleic Acids Res. 2005;33(17):5602-10 - PMID: 16199752 - PMCID: PMC1240114 - DOI: 10.1093/nar/gki867

Okuhira K, Fitzgerald ML, Sarracino DA, Manning JJ, Bell SA, Goss JL, Freeman MW

Purification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol efflux.
J Biol Chem. 2005;280(47):39653-64 - PMID: 16192269 - DOI: 10.1074/jbc.M510187200

Ichida JK, Horhota A, Zou K, McLaughlin LW, Szostak JW

High fidelity TNA synthesis by Therminator polymerase.
Nucleic Acids Res. 2005;33(16):5219-25 - PMID: 16157867 - PMCID: PMC1214552 - DOI: 10.1093/nar/gki840

Storey JD, Xiao W, Leek JT, Tompkins RG, Davis RW

Significance analysis of time course microarray experiments.
Proc Natl Acad Sci U S A. 2005;102(36):12837-42 - PMID: 16141318 - PMCID: PMC1201697 - DOI: 10.1073/pnas.0504609102

M Freeman, Consultant editor 3rd edition Junge C, Skerret PJ, and Emond, SD.

What to do about high cholesterol
President and Fellows of Harvard College. Harvard Health Publications. 2005;:ePub

MW Freeman

Approach to the patient with hypercholesterolemia. In: Goroll A, May L, Mulley A, eds
Primary Care Medicine, 5th Edition. 2005;:ePub
Total: 2485