Publications for All Faculty

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Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A, Green T, Kuballa P, Barmada MM, Datta LW, Shugart YY, Griffiths AM, Targan SR, Ippoliti AF, Bernard EJ, Mei L, Nicolae DL, Regueiro M, Schumm LP, Steinhart AH, Rotter JI, Duerr RH, Cho JH, Daly MJ, Brant SR

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.
Nat Genet. 2007;39(5):596-604 - PMID: 17435756 - PMCID: PMC2757939 - DOI: 10.1038/ng2032

Wright DA, Thibodeau-Beganny S, Sander JD, Winfrey RJ, Hirsh AS, Eichtinger M, Fu F, Porteus MH, Dobbs D, Voytas DF, Joung JK

Standardized reagents and protocols for engineering zinc finger nucleases by modular assembly.
Nat Protoc. 2007;1(3):1637-52 - PMID: 17406455 - DOI: 10.1038/nprot.2006.259

Begun J, Gaiani JM, Rohde H, Mack D, Calderwood SB, Ausubel FM, Sifri CD

Staphylococcal biofilm exopolysaccharide protects against Caenorhabditis elegans immune defenses.
PLoS Pathog. 2007;3(4):e57 - PMID: 17447841 - PMCID: PMC1853117 - DOI: 10.1371/journal.ppat.0030057

Klein MB, Hayden D, Elson C, Nathens AB, Gamelli RL, Gibran NS, Herndon DN, Arnoldo B, Silver G, Schoenfeld D, Tompkins RG

The association between fluid administration and outcome following major burn: a multicenter study.
Ann Surg. 2007;245(4):622-8 - PMID: 17414612 - PMCID: PMC1877030 - DOI: 10.1097/01.sla.0000252572.50684.49

Hayes GD, Ruvkun G

Misexpression of the Caenorhabditis elegans miRNA let-7 is sufficient to drive developmental programs.
Cold Spring Harb Symp Quant Biol. 2007;71:21-7 - PMID: 17381276 - DOI: 10.1101/sqb.2006.71.018

Ferrari S, Galletti R, Denoux C, De Lorenzo G, Ausubel FM, Dewdney J

Resistance to Botrytis cinerea induced in Arabidopsis by elicitors is independent of salicylic acid, ethylene, or jasmonate signaling but requires PHYTOALEXIN DEFICIENT3.
Plant Physiol. 2007;144(1):367-79 - PMID: 17384165 - PMCID: PMC1913806 - DOI: 10.1104/pp.107.095596

Silver GM, Klein MB, Herndon DN, Gamelli RL, Gibran NS, Altstein L, McDonald-Smith GP, Tompkins RG, Hunt JL,

Standard operating procedures for the clinical management of patients enrolled in a prospective study of Inflammation and the Host Response to Thermal Injury.
J Burn Care Res. 2007;28(2):222-30 - PMID: 17351437 - DOI: 10.1097/BCR.0B013E318031AA44

Nathens AB, McMurray MK, Cuschieri J, Durr EA, Moore EE, Bankey PE, Freeman B, Harbrecht BG, Johnson JL, Minei JP, McKinley BA, Moore FA, Shapiro MB, West MA, Tompkins RG, Maier RV

The practice of venous thromboembolism prophylaxis in the major trauma patient.
J Trauma. 2007;62(3):557-62; discussion 562-3 - PMID: 17414328 - DOI: 10.1097/TA.0b013e318031b5f5

Giesecke AV, Joung JK

The bacterial two-hybrid system as a reporter system for analyzing protein-protein interactions.
CSH Protoc. 2007;2007:pdb.prot4672 - PMID: 21357036 - DOI: 10.1101/pdb.prot4672

Sheen J, He P

Nuclear actions in innate immune signaling.
Cell. 2007;128(5):821-3 - PMID: 17350565 - DOI: 10.1016/j.cell.2007.02.019

Cho YH, Yoo SD, Sheen J

Glucose signaling through nuclear hexokinase1 complex in Arabidopsis.
Plant Signal Behav. 2007;2(2):123-4 - PMID: 19704756 - PMCID: PMC2633915 - DOI: 10.4161/psb.2.2.3894

Curran SP, Ruvkun G

Lifespan regulation by evolutionarily conserved genes essential for viability.
PLoS Genet. 2007;3(4):e56 - PMID: 17411345 - PMCID: PMC1847696 - DOI: 10.1371/journal.pgen.0030056

Meena , Sam M, Pierce K, Szostak JW, McLaughlin LW

2',3'-Dideoxy-3'-thionucleoside triphosphates: syntheses and polymerase substrate activities.
Org Lett. 2007;9(6):1161-3 - PMID: 17319676 - DOI: 10.1021/ol070147w

Kiss RS, Kavaslar N, Okuhira K, Freeman MW, Walter S, Milne RW, McPherson R, Marcel YL

Genetic etiology of isolated low HDL syndrome: incidence and heterogeneity of efflux defects.
Arterioscler Thromb Vasc Biol. 2007;27(5):1139-45 - PMID: 17303779 - DOI: 10.1161/ATVBAHA.106.137646

Gavi S, Stuart LM, Kelly P, Melendez MM, Mynarcik DC, Gelato MC, McNurlan MA

Retinol-binding protein 4 is associated with insulin resistance and body fat distribution in nonobese subjects without type 2 diabetes.
J Clin Endocrinol Metab. 2007;92(5):1886-90 - PMID: 17299074 - DOI: 10.1210/jc.2006-1815

Shakhnovich EA, Hung DT, Pierson E, Lee K, Mekalanos JJ

Virstatin inhibits dimerization of the transcriptional activator ToxT.
Proc Natl Acad Sci U S A. 2007;104(7):2372-7 - PMID: 17283330 - PMCID: PMC1892951 - DOI: 10.1073/pnas.0611643104

Breger J, Fuchs BB, Aperis G, Moy TI, Ausubel FM, Mylonakis E

Antifungal chemical compounds identified using a C. elegans pathogenicity assay.
PLoS Pathog. 2007;3(2):e18 - PMID: 17274686 - PMCID: PMC1790726 - DOI: 10.1371/journal.ppat.0030018

He P, Shan L, Sheen J

The use of protoplasts to study innate immune responses.
Methods Mol Biol. 2006;354:1-9 - PMID: 17172739 - DOI: 10.1385/1-59259-966-4:1

Mahoney ZX, Sammut B, Xavier RJ, Cunningham J, Go G, Brim KL, Stappenbeck TS, Miner JH, Swat W

Discs-large homolog 1 regulates smooth muscle orientation in the mouse ureter.
Proc Natl Acad Sci U S A. 2006;103(52):19872-7 - PMID: 17172448 - PMCID: PMC1750896 - DOI: 10.1073/pnas.0609326103

Volkman SK, Sabeti PC, DeCaprio D, Neafsey DE, Schaffner SF, Milner DA, Daily JP, Sarr O, Ndiaye D, Ndir O, Mboup S, Duraisingh MT, Lukens A, Derr A, Stange-Thomann N, Waggoner S, Onofrio R, Ziaugra L, Mauceli E, Gnerre S, Jaffe DB, Zainoun J, Wiegand RC, Birren BW, Hartl DL, Galagan JE, Lander ES, Wirth DF

A genome-wide map of diversity in Plasmodium falciparum.
Nat Genet. 2007;39(1):113-9 - PMID: 17159979 - DOI: 10.1038/ng1930

Miletic AV, Graham DB, Montgrain V, Fujikawa K, Kloeppel T, Brim K, Weaver B, Schreiber R, Xavier R, Swat W

Vav proteins control MyD88-dependent oxidative burst.
Blood. 2007;109(8):3360-8 - PMID: 17158234 - PMCID: PMC1852252 - DOI: 10.1182/blood-2006-07-033662

Miletic AV, Graham DB, Montgrain V, Fujikawa K, Kloeppel T, Brim K, Weaver B, Schreiber R, Xavier R, Swat W

Vav proteins control MyD88-dependent oxidative burst.
Blood. 2007;109(8):3360-8 - PMID: 17158234 - PMCID: PMC1852252 - DOI: 10.1182/blood-2006-07-033662

Stuart LM, Boulais J, Charriere GM, Hennessy EJ, Brunet S, Jutras I, Goyette G, Rondeau C, Letarte S, Huang H, Ye P, Morales F, Kocks C, Bader JS, Desjardins M, Ezekowitz RA

A systems biology analysis of the Drosophila phagosome.
Nature. 2007;445(7123):95-101 - PMID: 17151602 - DOI: 10.1038/nature05380

Lewis K, Ausubel FM

Prospects for plant-derived antibacterials.
Nat Biotechnol. 2006;24(12):1504-7 - PMID: 17160050 - DOI: 10.1038/nbt1206-1504

Fitzgerald ML, Xavier R, Haley KJ, Welti R, Goss JL, Brown CE, Zhuang DZ, Bell SA, Lu N, McKee M, Seed B, Freeman MW

ABCA3 inactivation in mice causes respiratory failure, loss of pulmonary surfactant, and depletion of lung phosphatidylglycerol.
J Lipid Res. 2007;48(3):621-32 - PMID: 17142808 - DOI: 10.1194/jlr.M600449-JLR200
Total: 2489