Publications for All Faculty

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Zhang Q, Carter EA, Ma B, Fischman AJ, Tompkins RG

Burn-related metabolic and signaling changes in rat brain.
J Burn Care Res. 2008;29(2):346-52 - PMID: 18354292 - DOI: 10.1097/BCR.0b013e3181667387

Ketteler R, Sun Z, Kovacs KF, He WW, Seed B

A pathway sensor for genome-wide screens of intracellular proteolytic cleavage.
Genome Biol. 2008;9(4):R64 - PMID: 18387192 - PMCID: PMC2643935 - DOI: 10.1186/gb-2008-9-4-r64

Russom A, Sethu P, Irimia D, Mindrinos MN, Calvano SE, Garcia I, Finnerty C, Tannahill C, Abouhamze A, Wilhelmy J, López MC, Baker HV, Herndon DN, Lowry SF, Maier RV, Davis RW, Moldawer LL, Tompkins RG, Toner M,

Microfluidic leukocyte isolation for gene expression analysis in critically ill hospitalized patients.
Clin Chem. 2008;54(5):891-900 - PMID: 18375483 - PMCID: PMC4011019 - DOI: 10.1373/clinchem.2007.099150

Powell JR, Ausubel FM

Models of Caenorhabditis elegans infection by bacterial and fungal pathogens.
Methods Mol Biol. 2008;415:403-27 - PMID: 18370168 - DOI: 10.1007/978-1-59745-570-1_24

Schöbel S, Neumann S, Hertweck M, Dislich B, Kuhn PH, Kremmer E, Seed B, Baumeister R, Haass C, Lichtenthaler SF

A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein.
J Biol Chem. 2008;283(21):14257-68 - PMID: 18353773 - DOI: 10.1074/jbc.M801531200

Pruett-Miller SM, Connelly JP, Maeder ML, Joung JK, Porteus MH

Comparison of zinc finger nucleases for use in gene targeting in mammalian cells.
Mol Ther. 2008;16(4):707-17 - PMID: 18334988 - DOI: 10.1038/mt.2008.20

Thibodeau-Beganny S, Joung JK

Engineering Cys2His2 zinc finger domains using a bacterial cell-based two-hybrid selection system.
Methods Mol Biol. 2008;408:317-34 - PMID: 18314590 - DOI: 10.1007/978-1-59745-547-3_17

Duerr EM, Mizukami Y, Ng A, Xavier RJ, Kikuchi H, Deshpande V, Warshaw AL, Glickman J, Kulke MH, Chung DC

Defining molecular classifications and targets in gastroenteropancreatic neuroendocrine tumors through DNA microarray analysis.
Endocr Relat Cancer. 2008;15(1):243-56 - PMID: 18310291 - DOI: 10.1677/ERC-07-0194

Sims KB, Pastores GM, Weinreb NJ, Barranger J, Rosenbloom BE, Packman S, Kaplan P, Mankin H, Xavier R, Angell J, Fitzpatrick MA, Rosenthal D

Improvement of bone disease by imiglucerase (Cerezyme) therapy in patients with skeletal manifestations of type 1 Gaucher disease: results of a 48-month longitudinal cohort study.
Clin Genet. 2008;73(5):430-40 - PMID: 18312448 - PMCID: PMC2440418 - DOI: 10.1111/j.1399-0004.2008.00978.x

Di Carlo D, Edd JF, Irimia D, Tompkins RG, Toner M

Equilibrium separation and filtration of particles using differential inertial focusing.
Anal Chem. 2008;80(6):2204-11 - PMID: 18275222 - DOI: 10.1021/ac702283m

Xavier RJ, Huett A, Rioux JD

Autophagy as an important process in gut homeostasis and Crohn's disease pathogenesis.
Gut. 2008;57(6):717-20 - PMID: 18272545 - PMCID: PMC2735854 - DOI: 10.1136/gut.2007.134254

Monnard PA, Szostak JW

Metal-ion catalyzed polymerization in the eutectic phase in water-ice: a possible approach to template-directed RNA polymerization.
J Inorg Biochem. 2008;102(5-6):1104-11 - PMID: 18329104 - DOI: 10.1016/j.jinorgbio.2008.01.026

Miyata S, Begun J, Troemel ER, Ausubel FM

DAF-16-dependent suppression of immunity during reproduction in Caenorhabditis elegans.
Genetics. 2008;178(2):903-18 - PMID: 18245330 - PMCID: PMC2248360 - DOI: 10.1534/genetics.107.083923

Toner M, Tompkins RG

Invention, innovation, entrepreneurship in academic medical centers.
Surgery. 2008;143(2):168-71 - PMID: 18242329 - PMCID: PMC2408552 - DOI: 10.1016/j.surg.2007.11.004

Stuart LM, Ezekowitz RA

Phagocytosis and comparative innate immunity: learning on the fly.
Nat Rev Immunol. 2008;8(2):131-41 - PMID: 18219310 - DOI: 10.1038/nri2240

Tzika AA, Mintzopoulos D, Padfield K, Wilhelmy J, Mindrinos MN, Yu H, Cao H, Zhang Q, Astrakas LG, Zhang J, Yu YM, Rahme LG, Tompkins RG

Reduced rate of adenosine triphosphate synthesis by in vivo 31P nuclear magnetic resonance spectroscopy and downregulation of PGC-1beta in distal skeletal muscle following burn.
Int J Mol Med. 2008;21(2):201-8 - PMID: 18204786

Sugimoto K, Ogawa A, Mizoguchi E, Shimomura Y, Andoh A, Bhan AK, Blumberg RS, Xavier RJ, Mizoguchi A

IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis.
J Clin Invest. 2008;118(2):534-44 - PMID: 18172556 - PMCID: PMC2157567 - DOI: 10.1172/JCI33194

Yoo SD, Cho YH, Tena G, Xiong Y, Sheen J

Dual control of nuclear EIN3 by bifurcate MAPK cascades in C2H4 signalling.
Nature. 2008;451(7180):789-95 - PMID: 18273012 - PMCID: PMC3488589 - DOI: 10.1038/nature06543

Gavi S, Qurashi S, Stuart LM, Lau R, Melendez MM, Mynarcik DC, McNurlan MA, Gelato MC

Influence of age on the association of retinol-binding protein 4 with metabolic syndrome.
Obesity (Silver Spring). 2008;16(4):893-5 - PMID: 18239568 - DOI: 10.1038/oby.2007.138

Goyette P, Lefebvre C, Ng A, Brant SR, Cho JH, Duerr RH, Silverberg MS, Taylor KD, Latiano A, Aumais G, Deslandres C, Jobin G, Annese V, Daly MJ, Xavier RJ, Rioux JD

Gene-centric association mapping of chromosome 3p implicates MST1 in IBD pathogenesis.
Mucosal Immunol. 2008;1(2):131-8 - PMID: 19079170 - PMCID: PMC4550306 - DOI: 10.1038/mi.2007.15

Yagi T, Giallourakis C, Mohanty S, Scheidig C, Shen J, Zheng H, Xavier RJ, Shaw AC

Defective signal transduction in B lymphocytes lacking presenilin proteins.
Proc Natl Acad Sci U S A. 2008;105(3):979-84 - PMID: 18195359 - PMCID: PMC2242696 - DOI: 10.1073/pnas.0707755105

Brass AL, Dykxhoorn DM, Benita Y, Yan N, Engelman A, Xavier RJ, Lieberman J, Elledge SJ

Identification of host proteins required for HIV infection through a functional genomic screen.
Science. 2008;319(5865):921-6 - PMID: 18187620 - DOI: 10.1126/science.1152725

Pierce ML, Weston MD, Fritzsch B, Gabel HW, Ruvkun G, Soukup GA

MicroRNA-183 family conservation and ciliated neurosensory organ expression.
Evol Dev. 2008;10(1):106-13 - PMID: 18184361 - PMCID: PMC2637451 - DOI: 10.1111/j.1525-142X.2007.00217.x

Ip WK, Takahashi K, Moore KJ, Stuart LM, Ezekowitz RA

Mannose-binding lectin enhances Toll-like receptors 2 and 6 signaling from the phagosome.
J Exp Med. 2008;205(1):169-81 - PMID: 18180310 - PMCID: PMC2234382 - DOI: 10.1084/jem.20071164

Huett A, Xavier R

SNPping away at the pathogenesis of Crohn's disease.
Inflamm Bowel Dis. 2008;14(1):136-7 - PMID: 17941076 - DOI: 10.1002/ibd.20306
Total: 2533