Publications for All Faculty

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Shan L, He P, Li J, Heese A, Peck SC, Nürnberger T, Martin GB, Sheen J

Bacterial effectors target the common signaling partner BAK1 to disrupt multiple MAMP receptor-signaling complexes and impede plant immunity.
Cell Host Microbe. 2008;4(1):17-27 - PMID: 18621007 - PMCID: PMC2830012 - DOI: 10.1016/j.chom.2008.05.017

Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmada MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO, Murtha MT, Regueiro MD, Rotter JI, Schumm LP, Steinhart AH, Targan SR, Xavier RJ, , Libioulle C, Sandor C, Lathrop M, Belaiche J, Dewit O, Gut I, Heath S, Laukens D, Mni M, Rutgeerts P, Van Gossum A, Zelenika D, Franchimont D, Hugot JP, de Vos M, Vermeire S, Louis E, , , Cardon LR, Anderson CA, Drummond H, Nimmo E, Ahmad T, Prescott NJ, Onnie CM, Fisher SA, Marchini J, Ghori J, Bumpstead S, Gwilliam R, Tremelling M, Deloukas P, Mansfield J, Jewell D, Satsangi J, Mathew CG, Parkes M, Georges M, Daly MJ

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.
Nat Genet. 2008;40(8):955-62 - PMID: 18587394 - PMCID: PMC2574810 - DOI: 10.1038/ng.175

Sena MJ, Utter GH, Cuschieri J, Maier RV, Tompkins RG, Harbrecht BG, Moore EE, O'Keefe GE

Early supplemental parenteral nutrition is associated with increased infectious complications in critically ill trauma patients.
J Am Coll Surg. 2008;207(4):459-67 - PMID: 18926446 - PMCID: PMC4002002 - DOI: 10.1016/j.jamcollsurg.2008.04.028

Ruvkun G

Tiny RNA: Where do we come from? What are we? Where are we going?
Trends Plant Sci. 2008;13(7):313-6 - PMID: 18562240 - DOI: 10.1016/j.tplants.2008.05.005

Cathomen T, Joung JK

Zinc-finger nucleases: the next generation emerges.
Mol Ther. 2008;16(7):1200-7 - PMID: 18545224 - DOI: 10.1038/mt.2008.114

Lemaitre B, Ausubel FM

Animal models for host-pathogen interactions.
Curr Opin Microbiol. 2008;11(3):249-50 - PMID: 18539076 - DOI: 10.1016/j.mib.2008.05.002

Mansy SS, Schrum JP, Krishnamurthy M, Tobé S, Treco DA, Szostak JW

Template-directed synthesis of a genetic polymer in a model protocell.
Nature. 2008;454(7200):122-5 - PMID: 18528332 - PMCID: PMC2743009 - DOI: 10.1038/nature07018

Samuelson AV, Klimczak RR, Thompson DB, Carr CE, Ruvkun G

Identification of Caenorhabditis elegans genes regulating longevity using enhanced RNAi-sensitive strains.
Cold Spring Harb Symp Quant Biol. 2008;72:489-97 - PMID: 18419309 - DOI: 10.1101/sqb.2007.72.068

Ketteler R, Seed B

Quantitation of autophagy by luciferase release assay.
Autophagy. 2008;4(6):801-6 - PMID: 18641457 - PMCID: PMC2910585 - DOI: 10.4161/auto.6401

Tzika AA, Astrakas LG, Cao H, Mintzopoulos D, Zhang Q, Padfield K, Yu H, Mindrinos MN, Rahme LG, Tompkins RG

Murine intramyocellular lipids quantified by NMR act as metabolic biomarkers in burn trauma.
Int J Mol Med. 2008;21(6):825-32 - PMID: 18506378

Freeman RM, Wu M, Cordonnier-Pratt MM, Pratt LH, Gruber CE, Smith M, Lander ES, Stange-Thomann N, Lowe CJ, Gerhart J, Kirschner M

cDNA sequences for transcription factors and signaling proteins of the hemichordate Saccoglossus kowalevskii: efficacy of the expressed sequence tag (EST) approach for evolutionary and developmental studies of a new organism.
Biol Bull. 2008;214(3):284-302 - PMID: 18574105 - DOI: 10.2307/25470670

Denoux C, Galletti R, Mammarella N, Gopalan S, Werck D, De Lorenzo G, Ferrari S, Ausubel FM, Dewdney J

Activation of defense response pathways by OGs and Flg22 elicitors in Arabidopsis seedlings.
Mol Plant. 2008;1(3):423-45 - PMID: 19825551 - PMCID: PMC2954645 - DOI: 10.1093/mp/ssn019

Patel DS, Fang LL, Svy DK, Ruvkun G, Li W

Genetic identification of HSD-1, a conserved steroidogenic enzyme that directs larval development in Caenorhabditis elegans.
Development. 2008;135(13):2239-49 - PMID: 18495818 - DOI: 10.1242/dev.016972

Tamehiro N, Zhou S, Okuhira K, Benita Y, Brown CE, Zhuang DZ, Latz E, Hornemann T, von Eckardstein A, Xavier RJ, Freeman MW, Fitzgerald ML

SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter.
Biochemistry. 2008;47(23):6138-47 - PMID: 18484747 - PMCID: PMC2504083 - DOI: 10.1021/bi800182t

Huett A, Xavier RJ

Neither hide nor hair: the difficulty of identifying useful disease biomarkers.
Gastroenterology. 2008;134(7):2164-8 - PMID: 18486617 - DOI: 10.1053/j.gastro.2008.04.013

Karve A, Rauh BL, Xia X, Kandasamy M, Meagher RB, Sheen J, Moore BD

Expression and evolutionary features of the hexokinase gene family in Arabidopsis.
Planta. 2008;228(3):411-25 - PMID: 18481082 - PMCID: PMC2953952 - DOI: 10.1007/s00425-008-0746-9

Müller B, Sheen J

Cytokinin and auxin interaction in root stem-cell specification during early embryogenesis.
Nature. 2008;453(7198):1094-7 - PMID: 18463635 - PMCID: PMC2601652 - DOI: 10.1038/nature06943

Simon DJ, Madison JM, Conery AL, Thompson-Peer KL, Soskis M, Ruvkun GB, Kaplan JM, Kim JK

The microRNA miR-1 regulates a MEF-2-dependent retrograde signal at neuromuscular junctions.
Cell. 2008;133(5):903-15 - PMID: 18510933 - PMCID: PMC2553566 - DOI: 10.1016/j.cell.2008.04.035

Ramirez CL, Foley JE, Wright DA, Müller-Lerch F, Rahman SH, Cornu TI, Winfrey RJ, Sander JD, Fu F, Townsend JA, Cathomen T, Voytas DF, Joung JK

Unexpected failure rates for modular assembly of engineered zinc fingers.
Nat Methods. 2008;5(5):374-5 - PMID: 18446154 - PMCID: PMC7880305 - DOI: 10.1038/nmeth0508-374

Cabral CB, Bullock KH, Bischoff DJ, Tompkins RG, Yu YM, Kelleher JK

Estimating glutathione synthesis with deuterated water: a model for peptide biosynthesis.
Anal Biochem. 2008;379(1):40-4 - PMID: 18486587 - PMCID: PMC4065382 - DOI: 10.1016/j.ab.2008.04.042

Gabel HW, Ruvkun G

The exonuclease ERI-1 has a conserved dual role in 5.8S rRNA processing and RNAi.
Nat Struct Mol Biol. 2008;15(5):531-3 - PMID: 18438419 - PMCID: PMC2910399 - DOI: 10.1038/nsmb.1411

Seed B, Xavier R

Spinophilin and the immune synapse.
J Cell Biol. 2008;181(2):181-3 - PMID: 18411314 - PMCID: PMC2315665 - DOI: 10.1083/jcb.200803120

Subtelny AO, Hartman MC, Szostak JW

Ribosomal synthesis of N-methyl peptides.
J Am Chem Soc. 2008;130(19):6131-6 - PMID: 18402453 - PMCID: PMC2728122 - DOI: 10.1021/ja710016v

Liberati NT, Urbach JM, Thurber TK, Wu G, Ausubel FM

Comparing insertion libraries in two Pseudomonas aeruginosa strains to assess gene essentiality.
Methods Mol Biol. 2008;416:153-69 - PMID: 18392966 - DOI: 10.1007/978-1-59745-321-9_10

Zhang Q, Ma B, Fischman AJ, Tompkins RG, Carter EA

Increased uncoupling protein 1 mRNA expression in mice brown adipose tissue after burn injury.
J Burn Care Res. 2008;29(2):358-62 - PMID: 18354294 - DOI: 10.1097/BCR.0b013e318166739c
Total: 2483