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Irazoqui JE, Ng A, Xavier RJ, Ausubel FM

Role for beta-catenin and HOX transcription factors in Caenorhabditis elegans and mammalian host epithelial-pathogen interactions.
Proc Natl Acad Sci U S A. 2008;105(45):17469-74 - PMID: 18981407 - PMCID: PMC2582251 - DOI: 10.1073/pnas.0809527105

Wang MC, O'Rourke EJ, Ruvkun G

Fat metabolism links germline stem cells and longevity in C. elegans.
Science. 2008;322(5903):957-60 - PMID: 18988854 - PMCID: PMC2760269 - DOI: 10.1126/science.1162011

Zuo Y, Zhuang DZ, Han R, Isaac G, Tobin JJ, McKee M, Welti R, Brissette JL, Fitzgerald ML, Freeman MW

ABCA12 maintains the epidermal lipid permeability barrier by facilitating formation of ceramide linoleic esters.
J Biol Chem. 2008;283(52):36624-35 - PMID: 18957418 - PMCID: PMC2605993 - DOI: 10.1074/jbc.M807377200

Manning-Tobin JJ, Moore KJ, Seimon TA, Bell SA, Sharuk M, Alvarez-Leite JI, de Winther MP, Tabas I, Freeman MW

Loss of SR-A and CD36 activity reduces atherosclerotic lesion complexity without abrogating foam cell formation in hyperlipidemic mice.
Arterioscler Thromb Vasc Biol. 2009;29(1):19-26 - PMID: 18948635 - PMCID: PMC2666043 - DOI: 10.1161/ATVBAHA.108.176644

Ramon M, Rolland F, Sheen J

Sugar sensing and signaling.
Arabidopsis Book. 2008;6:e0117 - PMID: 22303242 - PMCID: PMC3243355 - DOI: 10.1199/tab.0117

Isenbarger TA, Carr CE, Johnson SS, Finney M, Church GM, Gilbert W, Zuber MT, Ruvkun G

The most conserved genome segments for life detection on Earth and other planets.
Orig Life Evol Biosph. 2008;38(6):517-33 - PMID: 18853276 - DOI: 10.1007/s11084-008-9148-z

Kuballa P, Huett A, Rioux JD, Daly MJ, Xavier RJ

Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant.
PLoS One. 2008;3(10):e3391 - PMID: 18852889 - PMCID: PMC2566595 - DOI: 10.1371/journal.pone.0003391

Cadwell K, Liu JY, Brown SL, Miyoshi H, Loh J, Lennerz JK, Kishi C, Kc W, Carrero JA, Hunt S, Stone CD, Brunt EM, Xavier RJ, Sleckman BP, Li E, Mizushima N, Stappenbeck TS, Virgin HW

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells.
Nature. 2008;456(7219):259-63 - PMID: 18849966 - PMCID: PMC2695978 - DOI: 10.1038/nature07416

Ruvkun G

The perfect storm of tiny RNAs.
Nat Med. 2008;14(10):1041-5 - PMID: 18841145 - DOI: 10.1038/nm1008-1041

Huang R, Barber TA, Schmidt MA, Tompkins RG, Toner M, Bianchi DW, Kapur R, Flejter WL

A microfluidics approach for the isolation of nucleated red blood cells (NRBCs) from the peripheral blood of pregnant women.
Prenat Diagn. 2008;28(10):892-9 - PMID: 18821715 - PMCID: PMC4482103 - DOI: 10.1002/pd.2079

Litovchick A, Szostak JW

Selection of cyclic peptide aptamers to HCV IRES RNA using mRNA display.
Proc Natl Acad Sci U S A. 2008;105(40):15293-8 - PMID: 18824687 - PMCID: PMC2556359 - DOI: 10.1073/pnas.0805837105

Finnerty CC, Jeschke MG, Herndon DN, Gamelli R, Gibran N, Klein M, Silver G, Arnoldo B, Remick D, Tompkins RG,

Temporal cytokine profiles in severely burned patients: a comparison of adults and children.
Mol Med. 2008;14(9-10):553-60 - PMID: 18548133 - PMCID: PMC2424320 - DOI: 10.2119/2007-00132.Finnerty

Fu F, Sander JD, Maeder M, Thibodeau-Beganny S, Joung JK, Dobbs D, Miller L, Voytas DF

Zinc Finger Database (ZiFDB): a repository for information on C2H2 zinc fingers and engineered zinc-finger arrays.
Nucleic Acids Res. 2009;37(Database issue):D279-83 - PMID: 18812396 - PMCID: PMC2686427 - DOI: 10.1093/nar/gkn606

Galletti R, Denoux C, Gambetta S, Dewdney J, Ausubel FM, De Lorenzo G, Ferrari S

The AtrbohD-mediated oxidative burst elicited by oligogalacturonides in Arabidopsis is dispensable for the activation of defense responses effective against Botrytis cinerea.
Plant Physiol. 2008;148(3):1695-706 - PMID: 18790995 - PMCID: PMC2577270 - DOI: 10.1104/pp.108.127845

Fischer SE, Butler MD, Pan Q, Ruvkun G

Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7.
Nature. 2008;455(7212):491-6 - PMID: 18784652 - PMCID: PMC2756026 - DOI: 10.1038/nature07274

Thomson CE, McCulloch M, Sorenson A, Barnett SC, Seed BV, Griffiths IR, McLaughlin M

Myelinated, synapsing cultures of murine spinal cord--validation as an in vitro model of the central nervous system.
Eur J Neurosci. 2008;28(8):1518-35 - PMID: 18793322 - PMCID: PMC2777255 - DOI: 10.1111/j.1460-9568.2008.06415.x

Mansy SS, Szostak JW

Thermostability of model protocell membranes.
Proc Natl Acad Sci U S A. 2008;105(36):13351-5 - PMID: 18768808 - PMCID: PMC2528865 - DOI: 10.1073/pnas.0805086105

McCarroll SA, Huett A, Kuballa P, Chilewski SD, Landry A, Goyette P, Zody MC, Hall JL, Brant SR, Cho JH, Duerr RH, Silverberg MS, Taylor KD, Rioux JD, Altshuler D, Daly MJ, Xavier RJ

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease.
Nat Genet. 2008;40(9):1107-12 - PMID: 19165925 - PMCID: PMC2731799 - DOI: 10.1038/ng.215

Krishnan MN, Ng A, Sukumaran B, Gilfoy FD, Uchil PD, Sultana H, Brass AL, Adametz R, Tsui M, Qian F, Montgomery RR, Lev S, Mason PW, Koski RA, Elledge SJ, Xavier RJ, Agaisse H, Fikrig E

RNA interference screen for human genes associated with West Nile virus infection.
Nature. 2008;455(7210):242-5 - PMID: 18690214 - PMCID: PMC3136529 - DOI: 10.1038/nature07207

KJ Moore and MW Freeman

Targeting innate immunity for CV benefit
Drug Discovery Today: Therapeutic Strategies. 2008;5:15-23

Medoff BD, Landry AL, Wittbold KA, Sandall BP, Derby MC, Cao Z, Adams JC, Xavier RJ

CARMA3 mediates lysophosphatidic acid-stimulated cytokine secretion by bronchial epithelial cells.
Am J Respir Cell Mol Biol. 2009;40(3):286-94 - PMID: 18757306 - PMCID: PMC2645526 - DOI: 10.1165/rcmb.2008-0129OC

Baena-González E, Sheen J

Convergent energy and stress signaling.
Trends Plant Sci. 2008;13(9):474-82 - PMID: 18701338 - PMCID: PMC3075853 - DOI: 10.1016/j.tplants.2008.06.006

Xavier RJ, Rioux JD

Genome-wide association studies: a new window into immune-mediated diseases.
Nat Rev Immunol. 2008;8(8):631-43 - PMID: 18654571 - PMCID: PMC2750781 - DOI: 10.1038/nri2361

Xavier RJ, Rioux JD

Genome-wide association studies: a new window into immune-mediated diseases.
Nat Rev Immunol. 2008;8(8):631-43 - PMID: 18654571 - PMCID: PMC2750781 - DOI: 10.1038/nri2361

Labbé C, Goyette P, Lefebvre C, Stevens C, Green T, Tello-Ruiz MK, Cao Z, Landry AL, Stempak J, Annese V, Latiano A, Brant SR, Duerr RH, Taylor KD, Cho JH, Steinhart AH, Daly MJ, Silverberg MS, Xavier RJ, Rioux JD

MAST3: a novel IBD risk factor that modulates TLR4 signaling.
Genes Immun. 2008;9(7):602-12 - PMID: 18650832 - PMCID: PMC2574831 - DOI: 10.1038/gene.2008.57
Total: 2489