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Mansy SS, Szostak JW

Thermostability of model protocell membranes.

Proc Natl Acad Sci U S A. 2008;105(36):13351-5 - PMID: 18768808 - PMCID: PMC2528865 - DOI: 10.1073/pnas.0805086105
McCarroll SA, Huett A, Kuballa P, Chilewski SD, Landry A, Goyette P, Zody MC, Hall JL, Brant SR, Cho JH, Duerr RH, Silverberg MS, Taylor KD, Rioux JD, Altshuler D, Daly MJ, Xavier RJ

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease.

Nat Genet. 2008;40(9):1107-12 - PMID: 19165925 - PMCID: PMC2731799 - DOI: 10.1038/ng.215
KJ Moore and MW Freeman

Targeting innate immunity for CV benefit

Drug Discovery Today: Therapeutic Strategies. 2008;5:15-23
Krishnan MN, Ng A, Sukumaran B, Gilfoy FD, Uchil PD, Sultana H, Brass AL, Adametz R, Tsui M, Qian F, Montgomery RR, Lev S, Mason PW, Koski RA, Elledge SJ, Xavier RJ, Agaisse H, Fikrig E

RNA interference screen for human genes associated with West Nile virus infection.

Nature. 2008;455(7210):242-5 - PMID: 18690214 - PMCID: PMC3136529 - DOI: 10.1038/nature07207
Medoff BD, Landry AL, Wittbold KA, Sandall BP, Derby MC, Cao Z, Adams JC, Xavier RJ

CARMA3 mediates lysophosphatidic acid-stimulated cytokine secretion by bronchial epithelial cells.

Am J Respir Cell Mol Biol. 2009;40(3):286-94 - PMID: 18757306 - PMCID: PMC2645526 - DOI: 10.1165/rcmb.2008-0129OC
Baena-González E, Sheen J

Convergent energy and stress signaling.

Trends Plant Sci. 2008;13(9):474-82 - PMID: 18701338 - PMCID: PMC3075853 - DOI: 10.1016/j.tplants.2008.06.006
Xavier RJ, Rioux JD

Genome-wide association studies: a new window into immune-mediated diseases.

Nat Rev Immunol. 2008;8(8):631-43 - PMID: 18654571 - PMCID: PMC2750781 - DOI: 10.1038/nri2361
Xavier RJ, Rioux JD

Genome-wide association studies: a new window into immune-mediated diseases.

Nat Rev Immunol. 2008;8(8):631-43 - PMID: 18654571 - PMCID: PMC2750781 - DOI: 10.1038/nri2361
Labbé C, Goyette P, Lefebvre C, Stevens C, Green T, Tello-Ruiz MK, Cao Z, Landry AL, Stempak J, Annese V, Latiano A, Brant SR, Duerr RH, Taylor KD, Cho JH, Steinhart AH, Daly MJ, Silverberg MS, Xavier RJ, Rioux JD

MAST3: a novel IBD risk factor that modulates TLR4 signaling.

Genes Immun. 2008;9(7):602-12 - PMID: 18650832 - PMCID: PMC2574831 - DOI: 10.1038/gene.2008.57
Fujiki K, Duerr EM, Kikuchi H, Ng A, Xavier RJ, Mizukami Y, Imamura T, Kulke MH, Chung DC

Hoxc6 is overexpressed in gastrointestinal carcinoids and interacts with JunD to regulate tumor growth.

Gastroenterology. 2008;135(3):907-16, 916.e1-2 - PMID: 18655788 - PMCID: PMC3777410 - DOI: 10.1053/j.gastro.2008.06.034
Upadhyay G, Goessling W, North TE, Xavier R, Zon LI, Yajnik V

Molecular association between beta-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/beta-catenin signaling.

Oncogene. 2008;27(44):5845-55 - PMID: 18641688 - PMCID: PMC4774646 - DOI: 10.1038/onc.2008.202
Friedman CS, O'Donnell MA, Legarda-Addison D, Ng A, Cárdenas WB, Yount JS, Moran TM, Basler CF, Komuro A, Horvath CM, Xavier R, Ting AT

The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response.

EMBO Rep. 2008;9(9):930-6 - PMID: 18636086 - PMCID: PMC2529351 - DOI: 10.1038/embor.2008.136
Maheswaran S, Sequist LV, Nagrath S, Ulkus L, Brannigan B, Collura CV, Inserra E, Diederichs S, Iafrate AJ, Bell DW, Digumarthy S, Muzikansky A, Irimia D, Settleman J, Tompkins RG, Lynch TJ, Toner M, Haber DA

Detection of mutations in EGFR in circulating lung-cancer cells.

N Engl J Med. 2008;359(4):366-77 - PMID: 18596266 - PMCID: PMC3551471 - DOI: 10.1056/NEJMoa0800668
Adonizio A, Leal SM, Ausubel FM, Mathee K

Attenuation of Pseudomonas aeruginosa virulence by medicinal plants in a Caenorhabditis elegans model system.

J Med Microbiol. 2008;57(Pt 7):809-813 - PMID: 18566137 - DOI: 10.1099/jmm.0.47802-0
Shan L, He P, Li J, Heese A, Peck SC, Nürnberger T, Martin GB, Sheen J

Bacterial effectors target the common signaling partner BAK1 to disrupt multiple MAMP receptor-signaling complexes and impede plant immunity.

Cell Host Microbe. 2008;4(1):17-27 - PMID: 18621007 - PMCID: PMC2830012 - DOI: 10.1016/j.chom.2008.05.017
Maeder ML, Thibodeau-Beganny S, Osiak A, Wright DA, Anthony RM, Eichtinger M, Jiang T, Foley JE, Winfrey RJ, Townsend JA, Unger-Wallace E, Sander JD, Müller-Lerch F, Fu F, Pearlberg J, Göbel C, Dassie JP, Pruett-Miller SM, Porteus MH, Sgroi DC, Iafrate AJ, Dobbs D, McCray PB, Cathomen T, Voytas DF, Joung JK

Rapid open-source engineering of customized zinc-finger nucleases for highly efficient gene modification.

Mol Cell. 2008;31(2):294-301 - PMID: 18657511 - PMCID: PMC2535758 - DOI: 10.1016/j.molcel.2008.06.016
Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmada MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO, Murtha MT, Regueiro MD, Rotter JI, Schumm LP, Steinhart AH, Targan SR, Xavier RJ, , Libioulle C, Sandor C, Lathrop M, Belaiche J, Dewit O, Gut I, Heath S, Laukens D, Mni M, Rutgeerts P, Van Gossum A, Zelenika D, Franchimont D, Hugot JP, de Vos M, Vermeire S, Louis E, , , Cardon LR, Anderson CA, Drummond H, Nimmo E, Ahmad T, Prescott NJ, Onnie CM, Fisher SA, Marchini J, Ghori J, Bumpstead S, Gwilliam R, Tremelling M, Deloukas P, Mansfield J, Jewell D, Satsangi J, Mathew CG, Parkes M, Georges M, Daly MJ

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.

Nat Genet. 2008;40(8):955-62 - PMID: 18587394 - PMCID: PMC2574810 - DOI: 10.1038/ng.175
Sena MJ, Utter GH, Cuschieri J, Maier RV, Tompkins RG, Harbrecht BG, Moore EE, O'Keefe GE

Early supplemental parenteral nutrition is associated with increased infectious complications in critically ill trauma patients.

J Am Coll Surg. 2008;207(4):459-67 - PMID: 18926446 - PMCID: PMC4002002 - DOI: 10.1016/j.jamcollsurg.2008.04.028
Ruvkun G

Tiny RNA: Where do we come from? What are we? Where are we going?

Trends Plant Sci. 2008;13(7):313-6 - PMID: 18562240 - DOI: 10.1016/j.tplants.2008.05.005
Cathomen T, Joung JK

Zinc-finger nucleases: the next generation emerges.

Mol Ther. 2008;16(7):1200-7 - PMID: 18545224 - DOI: 10.1038/mt.2008.114
Lemaitre B, Ausubel FM

Animal models for host-pathogen interactions.

Curr Opin Microbiol. 2008;11(3):249-50 - PMID: 18539076 - DOI: 10.1016/j.mib.2008.05.002
Mansy SS, Schrum JP, Krishnamurthy M, Tobé S, Treco DA, Szostak JW

Template-directed synthesis of a genetic polymer in a model protocell.

Nature. 2008;454(7200):122-5 - PMID: 18528332 - PMCID: PMC2743009 - DOI: 10.1038/nature07018
Samuelson AV, Klimczak RR, Thompson DB, Carr CE, Ruvkun G

Identification of Caenorhabditis elegans genes regulating longevity using enhanced RNAi-sensitive strains.

Cold Spring Harb Symp Quant Biol. 2008;72:489-97 - PMID: 18419309 - DOI: 10.1101/sqb.2007.72.068
Ketteler R, Seed B

Quantitation of autophagy by luciferase release assay.

Autophagy. 2008;4(6):801-6 - PMID: 18641457 - PMCID: PMC2910585 - DOI: 10.4161/auto.6401
Tzika AA, Astrakas LG, Cao H, Mintzopoulos D, Zhang Q, Padfield K, Yu H, Mindrinos MN, Rahme LG, Tompkins RG

Murine intramyocellular lipids quantified by NMR act as metabolic biomarkers in burn trauma.

Int J Mol Med. 2008;21(6):825-32 - PMID: 18506378
Total: 2473