Publications for All Faculty

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Moy TI, Conery AL, Larkins-Ford J, Wu G, Mazitschek R, Casadei G, Lewis K, Carpenter AE, Ausubel FM

High-throughput screen for novel antimicrobials using a whole animal infection model.
ACS Chem Biol. 2009;4(7):527-33 - PMID: 19572548 - PMCID: PMC2745594 - DOI: 10.1021/cb900084v

Raychaudhuri S, Plenge RM, Rossin EJ, Ng AC, , Purcell SM, Sklar P, Scolnick EM, Xavier RJ, Altshuler D, Daly MJ

Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions.
PLoS Genet. 2009;5(6):e1000534 - PMID: 19557189 - PMCID: PMC2694358 - DOI: 10.1371/journal.pgen.1000534

Zou J, Maeder ML, Mali P, Pruett-Miller SM, Thibodeau-Beganny S, Chou BK, Chen G, Ye Z, Park IH, Daley GQ, Porteus MH, Joung JK, Cheng L

Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells.
Cell Stem Cell. 2009;5(1):97-110 - PMID: 19540188 - PMCID: PMC2720132 - DOI: 10.1016/j.stem.2009.05.023

Curran SP, Wu X, Riedel CG, Ruvkun G

A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants.
Nature. 2009;459(7250):1079-84 - PMID: 19506556 - PMCID: PMC2716045 - DOI: 10.1038/nature08106

Leb VM, Jahn-Schmid B, Kueng HJ, Schmetterer KG, Haiderer D, Neunkirchner A, Fischer GF, Hartl A, Thalhamer J, Steinberger P, Bohle B, Seed B, Pickl WF

Modulation of allergen-specific T-lymphocyte function by virus-like particles decorated with HLA class II molecules.
J Allergy Clin Immunol. 2009;124(1):121-8 - PMID: 19500826 - DOI: 10.1016/j.jaci.2009.04.008

Benita Y, Kikuchi H, Smith AD, Zhang MQ, Chung DC, Xavier RJ

An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia.
Nucleic Acids Res. 2009;37(14):4587-602 - PMID: 19491311 - PMCID: PMC2724271 - DOI: 10.1093/nar/gkp425

Szostak JW

Origins of life: Systems chemistry on early Earth.
Nature. 2009;459(7244):171-2 - PMID: 19444196 - DOI: 10.1038/459171a

Luong MX, Tam J, Lin Q, Hagendoorn J, Moore KJ, Padera TP, Seed B, Fukumura D, Kucherlapati R, Jain RK

Lack of lymphatic vessel phenotype in LYVE-1/CD44 double knockout mice.
J Cell Physiol. 2009;219(2):430-7 - PMID: 19170073 - PMCID: PMC2665001 - DOI: 10.1002/jcp.21686

Townsend JA, Wright DA, Winfrey RJ, Fu F, Maeder ML, Joung JK, Voytas DF

High-frequency modification of plant genes using engineered zinc-finger nucleases.
Nature. 2009;459(7245):442-5 - PMID: 19404258 - PMCID: PMC2743854 - DOI: 10.1038/nature07845

Litovchick A, Szostak JW

Retraction for Litovchick and Szostak. "Selection of cyclic peptide aptamers to HCV IRES RNA using mRNA display".
Proc Natl Acad Sci U S A. 2009;106(17):7263 - PMID: 19380733 - PMCID: PMC2678432 - DOI: 10.1073/pnas.0903110106

Yoo SD, Cho Y, Sheen J

Emerging connections in the ethylene signaling network.
Trends Plant Sci. 2009;14(5):270-9 - PMID: 19375376 - PMCID: PMC3063992 - DOI: 10.1016/j.tplants.2009.02.007

Huett A, Leong JM, Podolsky DK, Xavier RJ

The cytoskeletal scaffold Shank3 is recruited to pathogen-induced actin rearrangements.
Exp Cell Res. 2009;315(12):2001-11 - PMID: 19371741 - PMCID: PMC2693461 - DOI: 10.1016/j.yexcr.2009.04.003

Warren HS, Elson CM, Hayden DL, Schoenfeld DA, Cobb JP, Maier RV, Moldawer LL, Moore EE, Harbrecht BG, Pelak K, Cuschieri J, Herndon DN, Jeschke MG, Finnerty CC, Brownstein BH, Hennessy L, Mason PH, Tompkins RG,

A genomic score prognostic of outcome in trauma patients.
Mol Med. 2009;15(7-8):220-7 - PMID: 19593405 - PMCID: PMC2707513 - DOI: 10.2119/molmed.2009.00027

Tran C, Ouk S, Clegg NJ, Chen Y, Watson PA, Arora V, Wongvipat J, Smith-Jones PM, Yoo D, Kwon A, Wasielewska T, Welsbie D, Chen CD, Higano CS, Beer TM, Hung DT, Scher HI, Jung ME, Sawyers CL

Development of a second-generation antiandrogen for treatment of advanced prostate cancer.
Science. 2009;324(5928):787-90 - PMID: 19359544 - PMCID: PMC2981508 - DOI: 10.1126/science.1168175

Zhu TF, Szostak JW

Preparation of large monodisperse vesicles.
PLoS One. 2009;4(4):e5009 - PMID: 19347043 - PMCID: PMC2661144 - DOI: 10.1371/journal.pone.0005009

Urbach JM, Wei T, Liberati N, Grenfell-Lee D, Villanueva J, Wu G, Ausubel FM

Using PATIMDB to create bacterial transposon insertion mutant libraries.
Curr Protoc Mol Biol. 2009;Chapter 19:Unit 19.7 - PMID: 19343706 - PMCID: PMC4492697 - DOI: 10.1002/0471142727.mb1907s86

Huett A, Ng A, Cao Z, Kuballa P, Komatsu M, Daly MJ, Podolsky DK, Xavier RJ

A novel hybrid yeast-human network analysis reveals an essential role for FNBP1L in antibacterial autophagy.
J Immunol. 2009;182(8):4917-30 - PMID: 19342671 - PMCID: PMC2752416 - DOI: 10.4049/jimmunol.0803050

Zhu TF, Szostak JW

Coupled growth and division of model protocell membranes.
J Am Chem Soc. 2009;131(15):5705-13 - PMID: 19323552 - PMCID: PMC2669828 - DOI: 10.1021/ja900919c

Yin HN, Chai JK, Yu YM, Shen CA, Wu YQ, Yao YM, Liu H, Liang LM, Tompkins RG, Sheng ZY

Regulation of signaling pathways downstream of IGF-I/insulin by androgen in skeletal muscle of glucocorticoid-treated rats.
J Trauma. 2009;66(4):1083-90 - PMID: 19359918 - PMCID: PMC4085982 - DOI: 10.1097/TA.0b013e31817e7420

Chen JJ, Tsai CH, Cai X, Horhota AT, McLaughlin LW, Szostak JW

Enzymatic primer-extension with glycerol-nucleoside triphosphates on DNA templates.
PLoS One. 2009;4(3):e4949 - PMID: 19305495 - PMCID: PMC2654545 - DOI: 10.1371/journal.pone.0004949

Adams JC, Seed B, Lu N, Landry A, Xavier RJ

Selective activation of nuclear factor kappa B in the cochlea by sensory and inflammatory stress.
Neuroscience. 2009;160(2):530-9 - PMID: 19285117 - PMCID: PMC2673023 - DOI: 10.1016/j.neuroscience.2009.02.073

Adams JC, Seed B, Lu N, Landry A, Xavier RJ

Selective activation of nuclear factor kappa B in the cochlea by sensory and inflammatory stress.
Neuroscience. 2009;160(2):530-9 - PMID: 19285117 - PMCID: PMC2673023 - DOI: 10.1016/j.neuroscience.2009.02.073

Tai AW, Benita Y, Peng LF, Kim SS, Sakamoto N, Xavier RJ, Chung RT

A functional genomic screen identifies cellular cofactors of hepatitis C virus replication.
Cell Host Microbe. 2009;5(3):298-307 - PMID: 19286138 - PMCID: PMC2756022 - DOI: 10.1016/j.chom.2009.02.001

Foley JE, Yeh JR, Maeder ML, Reyon D, Sander JD, Peterson RT, Joung JK

Rapid mutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool ENgineering (OPEN).
PLoS One. 2009;4(2):e4348 - PMID: 19198653 - PMCID: PMC2634973 - DOI: 10.1371/journal.pone.0004348

Festen EA, Goyette P, Scott R, Annese V, Zhernakova A, Lian J, Lefèbvre C, Brant SR, Cho JH, Silverberg MS, Taylor KD, de Jong DJ, Stokkers PC, Mcgovern D, Palmieri O, Achkar JP, Xavier RJ, Daly MJ, Duerr RH, Wijmenga C, Weersma RK, Rioux JD

Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis.
Gut. 2009;58(6):799-804 - PMID: 19201773 - PMCID: PMC2757103 - DOI: 10.1136/gut.2008.166918
Total: 2489