Publications for All Faculty

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Li Q, Brass AL, Ng A, Hu Z, Xavier RJ, Liang TJ, Elledge SJ

A genome-wide genetic screen for host factors required for hepatitis C virus propagation.
Proc Natl Acad Sci U S A. 2009;106(38):16410-5 - PMID: 19717417 - PMCID: PMC2752535 - DOI: 10.1073/pnas.0907439106

Huett A, Xavier R

Building complex biological networks based upon model organisms: mapping the human autophagy interactome via a hybrid yeast-human protein interaction network.
Autophagy. 2009;5(6):884-6 - PMID: 19535904 - DOI: 10.4161/auto.9094

Xu B, Lv B, Feng Y, Xu G, Du J, Welihinda A, Sheng Z, Seed B, Chen Y

O-Spiro C-aryl glucosides as novel sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors.
Bioorg Med Chem Lett. 2009;19(19):5632-5 - PMID: 19700318 - DOI: 10.1016/j.bmcl.2009.08.030

Barczak AK, Hung DT

Productive steps toward an antimicrobial targeting virulence.
Curr Opin Microbiol. 2009;12(5):490-6 - PMID: 19631578 - PMCID: PMC2763366 - DOI: 10.1016/j.mib.2009.06.012

Tamehiro N, Mujawar Z, Zhou S, Zhuang DZ, Hornemann T, von Eckardstein A, Fitzgerald ML

Cell polarity factor Par3 binds SPTLC1 and modulates monocyte serine palmitoyltransferase activity and chemotaxis.
J Biol Chem. 2009;284(37):24881-90 - PMID: 19592499 - PMCID: PMC2757191 - DOI: 10.1074/jbc.M109.014365

Stephenson LM, Miller BC, Ng A, Eisenberg J, Zhao Z, Cadwell K, Graham DB, Mizushima NN, Xavier R, Virgin HW, Swat W

Identification of Atg5-dependent transcriptional changes and increases in mitochondrial mass in Atg5-deficient T lymphocytes.
Autophagy. 2009;5(5):625-35 - PMID: 19276668 - PMCID: PMC3737142 - DOI: 10.4161/auto.5.5.8133

Budin I, Bruckner RJ, Szostak JW

Formation of protocell-like vesicles in a thermal diffusion column.
J Am Chem Soc. 2009;131(28):9628-9 - PMID: 19601679 - PMCID: PMC2710859 - DOI: 10.1021/ja9029818

Ip WK, Takahashi K, Ezekowitz RA, Stuart LM

Mannose-binding lectin and innate immunity.
Immunol Rev. 2009;230(1):9-21 - PMID: 19594626 - DOI: 10.1111/j.1600-065X.2009.00789.x

Elenko MP, Szostak JW, van Oijen AM

Single-molecule imaging of an in vitro-evolved RNA aptamer reveals homogeneous ligand binding kinetics.
J Am Chem Soc. 2009;131(29):9866-7 - PMID: 19572753 - PMCID: PMC2716146 - DOI: 10.1021/ja901880v

Moy TI, Conery AL, Larkins-Ford J, Wu G, Mazitschek R, Casadei G, Lewis K, Carpenter AE, Ausubel FM

High-throughput screen for novel antimicrobials using a whole animal infection model.
ACS Chem Biol. 2009;4(7):527-33 - PMID: 19572548 - PMCID: PMC2745594 - DOI: 10.1021/cb900084v

Raychaudhuri S, Plenge RM, Rossin EJ, Ng AC, , Purcell SM, Sklar P, Scolnick EM, Xavier RJ, Altshuler D, Daly MJ

Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions.
PLoS Genet. 2009;5(6):e1000534 - PMID: 19557189 - PMCID: PMC2694358 - DOI: 10.1371/journal.pgen.1000534

Zou J, Maeder ML, Mali P, Pruett-Miller SM, Thibodeau-Beganny S, Chou BK, Chen G, Ye Z, Park IH, Daley GQ, Porteus MH, Joung JK, Cheng L

Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells.
Cell Stem Cell. 2009;5(1):97-110 - PMID: 19540188 - PMCID: PMC2720132 - DOI: 10.1016/j.stem.2009.05.023

Curran SP, Wu X, Riedel CG, Ruvkun G

A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants.
Nature. 2009;459(7250):1079-84 - PMID: 19506556 - PMCID: PMC2716045 - DOI: 10.1038/nature08106

Leb VM, Jahn-Schmid B, Kueng HJ, Schmetterer KG, Haiderer D, Neunkirchner A, Fischer GF, Hartl A, Thalhamer J, Steinberger P, Bohle B, Seed B, Pickl WF

Modulation of allergen-specific T-lymphocyte function by virus-like particles decorated with HLA class II molecules.
J Allergy Clin Immunol. 2009;124(1):121-8 - PMID: 19500826 - DOI: 10.1016/j.jaci.2009.04.008

Benita Y, Kikuchi H, Smith AD, Zhang MQ, Chung DC, Xavier RJ

An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia.
Nucleic Acids Res. 2009;37(14):4587-602 - PMID: 19491311 - PMCID: PMC2724271 - DOI: 10.1093/nar/gkp425

Szostak JW

Origins of life: Systems chemistry on early Earth.
Nature. 2009;459(7244):171-2 - PMID: 19444196 - DOI: 10.1038/459171a

Luong MX, Tam J, Lin Q, Hagendoorn J, Moore KJ, Padera TP, Seed B, Fukumura D, Kucherlapati R, Jain RK

Lack of lymphatic vessel phenotype in LYVE-1/CD44 double knockout mice.
J Cell Physiol. 2009;219(2):430-7 - PMID: 19170073 - PMCID: PMC2665001 - DOI: 10.1002/jcp.21686

Townsend JA, Wright DA, Winfrey RJ, Fu F, Maeder ML, Joung JK, Voytas DF

High-frequency modification of plant genes using engineered zinc-finger nucleases.
Nature. 2009;459(7245):442-5 - PMID: 19404258 - PMCID: PMC2743854 - DOI: 10.1038/nature07845

Litovchick A, Szostak JW

Retraction for Litovchick and Szostak. "Selection of cyclic peptide aptamers to HCV IRES RNA using mRNA display".
Proc Natl Acad Sci U S A. 2009;106(17):7263 - PMID: 19380733 - PMCID: PMC2678432 - DOI: 10.1073/pnas.0903110106

Yoo SD, Cho Y, Sheen J

Emerging connections in the ethylene signaling network.
Trends Plant Sci. 2009;14(5):270-9 - PMID: 19375376 - PMCID: PMC3063992 - DOI: 10.1016/j.tplants.2009.02.007

Huett A, Leong JM, Podolsky DK, Xavier RJ

The cytoskeletal scaffold Shank3 is recruited to pathogen-induced actin rearrangements.
Exp Cell Res. 2009;315(12):2001-11 - PMID: 19371741 - PMCID: PMC2693461 - DOI: 10.1016/j.yexcr.2009.04.003

Warren HS, Elson CM, Hayden DL, Schoenfeld DA, Cobb JP, Maier RV, Moldawer LL, Moore EE, Harbrecht BG, Pelak K, Cuschieri J, Herndon DN, Jeschke MG, Finnerty CC, Brownstein BH, Hennessy L, Mason PH, Tompkins RG,

A genomic score prognostic of outcome in trauma patients.
Mol Med. 2009;15(7-8):220-7 - PMID: 19593405 - PMCID: PMC2707513 - DOI: 10.2119/molmed.2009.00027

Tran C, Ouk S, Clegg NJ, Chen Y, Watson PA, Arora V, Wongvipat J, Smith-Jones PM, Yoo D, Kwon A, Wasielewska T, Welsbie D, Chen CD, Higano CS, Beer TM, Hung DT, Scher HI, Jung ME, Sawyers CL

Development of a second-generation antiandrogen for treatment of advanced prostate cancer.
Science. 2009;324(5928):787-90 - PMID: 19359544 - PMCID: PMC2981508 - DOI: 10.1126/science.1168175

Zhu TF, Szostak JW

Preparation of large monodisperse vesicles.
PLoS One. 2009;4(4):e5009 - PMID: 19347043 - PMCID: PMC2661144 - DOI: 10.1371/journal.pone.0005009

Urbach JM, Wei T, Liberati N, Grenfell-Lee D, Villanueva J, Wu G, Ausubel FM

Using PATIMDB to create bacterial transposon insertion mutant libraries.
Curr Protoc Mol Biol. 2009;Chapter 19:Unit 19.7 - PMID: 19343706 - PMCID: PMC4492697 - DOI: 10.1002/0471142727.mb1907s86
Total: 2498