Publications for All Faculty

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Tzika AA, Mintzopoulos D, Mindrinos M, Zhang J, Rahme LG, Tompkins RG

Microarray analysis suggests that burn injury results in mitochondrial dysfunction in human skeletal muscle.

Int J Mol Med. 2009;24(3):387-92 - PMID: 19639232 - PMCID: PMC3207251 - DOI: 10.3892/ijmm_00000244
M Freeman, Consultant editor, 4th edition. Buckley, Rita

What to do about high cholesterol

President and Fellows of Harvard College. Harvard Health Publications. 2009;:ePub
MW Freeman

Approach to the patient with hypercholesterolemia. In: Goroll A, May L, Mulley A, eds

Primary Care Medicine, 6th Edition. 2009;:ePub
Haydock GS and MW Freeman

Screening for hyperlipidemia. In: Goroll A and Mulley A, eds.

Primary Care Medicine, 6th Edition. 2009;:ePub
Li Q, Brass AL, Ng A, Hu Z, Xavier RJ, Liang TJ, Elledge SJ

A genome-wide genetic screen for host factors required for hepatitis C virus propagation.

Proc Natl Acad Sci U S A. 2009;106(38):16410-5 - PMID: 19717417 - PMCID: PMC2752535 - DOI: 10.1073/pnas.0907439106
Huett A, Xavier R

Building complex biological networks based upon model organisms: mapping the human autophagy interactome via a hybrid yeast-human protein interaction network.

Autophagy. 2009;5(6):884-6 - PMID: 19535904 - DOI: 10.4161/auto.9094
Xu B, Lv B, Feng Y, Xu G, Du J, Welihinda A, Sheng Z, Seed B, Chen Y

O-Spiro C-aryl glucosides as novel sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors.

Bioorg Med Chem Lett. 2009;19(19):5632-5 - PMID: 19700318 - DOI: 10.1016/j.bmcl.2009.08.030
Barczak AK, Hung DT

Productive steps toward an antimicrobial targeting virulence.

Curr Opin Microbiol. 2009;12(5):490-6 - PMID: 19631578 - PMCID: PMC2763366 - DOI: 10.1016/j.mib.2009.06.012
Tamehiro N, Mujawar Z, Zhou S, Zhuang DZ, Hornemann T, von Eckardstein A, Fitzgerald ML

Cell polarity factor Par3 binds SPTLC1 and modulates monocyte serine palmitoyltransferase activity and chemotaxis.

J Biol Chem. 2009;284(37):24881-90 - PMID: 19592499 - PMCID: PMC2757191 - DOI: 10.1074/jbc.M109.014365
Stephenson LM, Miller BC, Ng A, Eisenberg J, Zhao Z, Cadwell K, Graham DB, Mizushima NN, Xavier R, Virgin HW, Swat W

Identification of Atg5-dependent transcriptional changes and increases in mitochondrial mass in Atg5-deficient T lymphocytes.

Autophagy. 2009;5(5):625-35 - PMID: 19276668 - PMCID: PMC3737142 - DOI: 10.4161/auto.5.5.8133
Budin I, Bruckner RJ, Szostak JW

Formation of protocell-like vesicles in a thermal diffusion column.

J Am Chem Soc. 2009;131(28):9628-9 - PMID: 19601679 - PMCID: PMC2710859 - DOI: 10.1021/ja9029818
Ip WK, Takahashi K, Ezekowitz RA, Stuart LM

Mannose-binding lectin and innate immunity.

Immunol Rev. 2009;230(1):9-21 - PMID: 19594626 - DOI: 10.1111/j.1600-065X.2009.00789.x
Elenko MP, Szostak JW, van Oijen AM

Single-molecule imaging of an in vitro-evolved RNA aptamer reveals homogeneous ligand binding kinetics.

J Am Chem Soc. 2009;131(29):9866-7 - PMID: 19572753 - PMCID: PMC2716146 - DOI: 10.1021/ja901880v
Moy TI, Conery AL, Larkins-Ford J, Wu G, Mazitschek R, Casadei G, Lewis K, Carpenter AE, Ausubel FM

High-throughput screen for novel antimicrobials using a whole animal infection model.

ACS Chem Biol. 2009;4(7):527-33 - PMID: 19572548 - PMCID: PMC2745594 - DOI: 10.1021/cb900084v
Raychaudhuri S, Plenge RM, Rossin EJ, Ng AC, , Purcell SM, Sklar P, Scolnick EM, Xavier RJ, Altshuler D, Daly MJ

Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions.

PLoS Genet. 2009;5(6):e1000534 - PMID: 19557189 - PMCID: PMC2694358 - DOI: 10.1371/journal.pgen.1000534
Zou J, Maeder ML, Mali P, Pruett-Miller SM, Thibodeau-Beganny S, Chou BK, Chen G, Ye Z, Park IH, Daley GQ, Porteus MH, Joung JK, Cheng L

Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells.

Cell Stem Cell. 2009;5(1):97-110 - PMID: 19540188 - PMCID: PMC2720132 - DOI: 10.1016/j.stem.2009.05.023
Curran SP, Wu X, Riedel CG, Ruvkun G

A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants.

Nature. 2009;459(7250):1079-84 - PMID: 19506556 - PMCID: PMC2716045 - DOI: 10.1038/nature08106
Leb VM, Jahn-Schmid B, Kueng HJ, Schmetterer KG, Haiderer D, Neunkirchner A, Fischer GF, Hartl A, Thalhamer J, Steinberger P, Bohle B, Seed B, Pickl WF

Modulation of allergen-specific T-lymphocyte function by virus-like particles decorated with HLA class II molecules.

J Allergy Clin Immunol. 2009;124(1):121-8 - PMID: 19500826 - DOI: 10.1016/j.jaci.2009.04.008
Benita Y, Kikuchi H, Smith AD, Zhang MQ, Chung DC, Xavier RJ

An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia.

Nucleic Acids Res. 2009;37(14):4587-602 - PMID: 19491311 - PMCID: PMC2724271 - DOI: 10.1093/nar/gkp425
Szostak JW

Origins of life: Systems chemistry on early Earth.

Nature. 2009;459(7244):171-2 - PMID: 19444196 - DOI: 10.1038/459171a
Luong MX, Tam J, Lin Q, Hagendoorn J, Moore KJ, Padera TP, Seed B, Fukumura D, Kucherlapati R, Jain RK

Lack of lymphatic vessel phenotype in LYVE-1/CD44 double knockout mice.

J Cell Physiol. 2009;219(2):430-7 - PMID: 19170073 - PMCID: PMC2665001 - DOI: 10.1002/jcp.21686
Townsend JA, Wright DA, Winfrey RJ, Fu F, Maeder ML, Joung JK, Voytas DF

High-frequency modification of plant genes using engineered zinc-finger nucleases.

Nature. 2009;459(7245):442-5 - PMID: 19404258 - PMCID: PMC2743854 - DOI: 10.1038/nature07845
Litovchick A, Szostak JW

Retraction for Litovchick and Szostak. "Selection of cyclic peptide aptamers to HCV IRES RNA using mRNA display".

Proc Natl Acad Sci U S A. 2009;106(17):7263 - PMID: 19380733 - PMCID: PMC2678432 - DOI: 10.1073/pnas.0903110106
Yoo SD, Cho Y, Sheen J

Emerging connections in the ethylene signaling network.

Trends Plant Sci. 2009;14(5):270-9 - PMID: 19375376 - PMCID: PMC3063992 - DOI: 10.1016/j.tplants.2009.02.007
Huett A, Leong JM, Podolsky DK, Xavier RJ

The cytoskeletal scaffold Shank3 is recruited to pathogen-induced actin rearrangements.

Exp Cell Res. 2009;315(12):2001-11 - PMID: 19371741 - PMCID: PMC2693461 - DOI: 10.1016/j.yexcr.2009.04.003
Total: 2477