Publications for All Faculty

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Rajamani S, Ichida JK, Antal T, Treco DA, Leu K, Nowak MA, Szostak JW, Chen IA

Effect of stalling after mismatches on the error catastrophe in nonenzymatic nucleic acid replication.
J Am Chem Soc. 2010;132(16):5880-5 - PMID: 20359213 - PMCID: PMC2857888 - DOI: 10.1021/ja100780p

Millet YA, Danna CH, Clay NK, Songnuan W, Simon MD, Werck-Reichhart D, Ausubel FM

Innate immune responses activated in Arabidopsis roots by microbe-associated molecular patterns.
Plant Cell. 2010;22(3):973-90 - PMID: 20348432 - PMCID: PMC2861455 - DOI: 10.1105/tpc.109.069658

Okuhira K, Fitzgerald ML, Tamehiro N, Ohoka N, Suzuki K, Sawada J, Naito M, Nishimaki-Mogami T

Binding of PDZ-RhoGEF to ATP-binding cassette transporter A1 (ABCA1) induces cholesterol efflux through RhoA activation and prevention of transporter degradation.
J Biol Chem. 2010;285(21):16369-77 - PMID: 20348106 - PMCID: PMC2871504 - DOI: 10.1074/jbc.M109.061424

Meli VS, Osuna B, Ruvkun G, Frand AR

MLT-10 defines a family of DUF644 and proline-rich repeat proteins involved in the molting cycle of Caenorhabditis elegans.
Mol Biol Cell. 2010;21(10):1648-61 - PMID: 20335506 - PMCID: PMC2869372 - DOI: 10.1091/mbc.E08-07-0708

Beck PL, Ihara E, Hirota SA, MacDonald JA, Meng D, Nanthakumar NN, Podolsky DK, Xavier RJ

Exploring the interplay of barrier function and leukocyte recruitment in intestinal inflammation by targeting fucosyltransferase VII and trefoil factor 3.
Am J Physiol Gastrointest Liver Physiol. 2010;299(1):G43-53 - PMID: 20299601 - PMCID: PMC2904110 - DOI: 10.1152/ajpgi.00228.2009

McGovern DP, Gardet A, Törkvist L, Goyette P, Essers J, Taylor KD, Neale BM, Ong RT, Lagacé C, Li C, Green T, Stevens CR, Beauchamp C, Fleshner PR, Carlson M, D'Amato M, Halfvarson J, Hibberd ML, Lördal M, Padyukov L, Andriulli A, Colombo E, Latiano A, Palmieri O, Bernard EJ, Deslandres C, Hommes DW, de Jong DJ, Stokkers PC, Weersma RK, , Sharma Y, Silverberg MS, Cho JH, Wu J, Roeder K, Brant SR, Schumm LP, Duerr RH, Dubinsky MC, Glazer NL, Haritunians T, Ippoliti A, Melmed GY, Siscovick DS, Vasiliauskas EA, Targan SR, Annese V, Wijmenga C, Pettersson S, Rotter JI, Xavier RJ, Daly MJ, Rioux JD, Seielstad M

Genome-wide association identifies multiple ulcerative colitis susceptibility loci.
Nat Genet. 2010;42(4):332-7 - PMID: 20228799 - PMCID: PMC3087600 - DOI: 10.1038/ng.549

Stott SL, Lee RJ, Nagrath S, Yu M, Miyamoto DT, Ulkus L, Inserra EJ, Ulman M, Springer S, Nakamura Z, Moore AL, Tsukrov DI, Kempner ME, Dahl DM, Wu CL, Iafrate AJ, Smith MR, Tompkins RG, Sequist LV, Toner M, Haber DA, Maheswaran S

Isolation and characterization of circulating tumor cells from patients with localized and metastatic prostate cancer.
Sci Transl Med. 2010;2(25):25ra23 - PMID: 20424012 - PMCID: PMC3141292 - DOI: 10.1126/scitranslmed.3000403

Boudsocq M, Willmann MR, McCormack M, Lee H, Shan L, He P, Bush J, Cheng SH, Sheen J

Differential innate immune signalling via Ca(2+) sensor protein kinases.
Nature. 2010;464(7287):418-22 - PMID: 20164835 - PMCID: PMC2841715 - DOI: 10.1038/nature08794

Henn MR, Sullivan MB, Stange-Thomann N, Osburne MS, Berlin AM, Kelly L, Yandava C, Kodira C, Zeng Q, Weiand M, Sparrow T, Saif S, Giannoukos G, Young SK, Nusbaum C, Birren BW, Chisholm SW

Analysis of high-throughput sequencing and annotation strategies for phage genomes.
PLoS One. 2010;5(2):e9083 - PMID: 20140207 - PMCID: PMC2816706 - DOI: 10.1371/journal.pone.0009083

Kaufmann BB, Hung DT

The fast track to multidrug resistance.
Mol Cell. 2010;37(3):297-8 - PMID: 20159549 - DOI: 10.1016/j.molcel.2010.01.027

Fitzgerald ML, Mujawar Z, Tamehiro N

ABC transporters, atherosclerosis and inflammation.
Atherosclerosis. 2010;211(2):361-70 - PMID: 20138281 - PMCID: PMC2888932 - DOI: 10.1016/j.atherosclerosis.2010.01.011

Estes KA, Dunbar TL, Powell JR, Ausubel FM, Troemel ER

bZIP transcription factor zip-2 mediates an early response to Pseudomonas aeruginosa infection in Caenorhabditis elegans.
Proc Natl Acad Sci U S A. 2010;107(5):2153-8 - PMID: 20133860 - PMCID: PMC2836710 - DOI: 10.1073/pnas.0914643107

Li JF, Li L, Sheen J

Protocol: a rapid and economical procedure for purification of plasmid or plant DNA with diverse applications in plant biology.
Plant Methods. 2010;6(1):1 - PMID: 20180960 - PMCID: PMC2829548 - DOI: 10.1186/1746-4811-6-1

Mosier MJ, Pham TN, Klein MB, Gibran NS, Arnoldo BD, Gamelli RL, Tompkins RG, Herndon DN

Early acute kidney injury predicts progressive renal dysfunction and higher mortality in severely burned adults.
J Burn Care Res. 2010;31(1):83-92 - PMID: 20061841 - PMCID: PMC3045668 - DOI: 10.1097/BCR.0b013e3181cb8c87

Kueng HJ, Manta C, Haiderer D, Leb VM, Schmetterer KG, Neunkirchner A, Byrne RA, Scheinecker C, Steinberger P, Seed B, Pickl WF

Fluorosomes: a convenient new reagent to detect and block multivalent and complex receptor-ligand interactions.
FASEB J. 2010;24(5):1572-82 - PMID: 20056716 - PMCID: PMC2879947 - DOI: 10.1096/fj.09-137281

Irazoqui JE, Urbach JM, Ausubel FM

Evolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebrates.
Nat Rev Immunol. 2010;10(1):47-58 - PMID: 20029447 - PMCID: PMC2965059 - DOI: 10.1038/nri2689

Huett A, Xavier RJ

Autophagy at the gut interface: mucosal responses to stress and the consequences for inflammatory bowel diseases.
Inflamm Bowel Dis. 2010;16(1):152-74 - PMID: 19575363 - PMCID: PMC3954538 - DOI: 10.1002/ibd.20991

Stewart CR, Stuart LM, Wilkinson K, van Gils JM, Deng J, Halle A, Rayner KJ, Boyer L, Zhong R, Frazier WA, Lacy-Hulbert A, El Khoury J, Golenbock DT, Moore KJ

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer.
Nat Immunol. 2010;11(2):155-61 - PMID: 20037584 - PMCID: PMC2809046 - DOI: 10.1038/ni.1836

Cho YH, Sheen J, Yoo SD

Low glucose uncouples hexokinase1-dependent sugar signaling from stress and defense hormone abscisic acid and C2H4 responses in Arabidopsis.
Plant Physiol. 2010;152(3):1180-2 - PMID: 20034964 - PMCID: PMC2832269 - DOI: 10.1104/pp.109.148957

Foley JE, Maeder ML, Pearlberg J, Joung JK, Peterson RT, Yeh JR

Targeted mutagenesis in zebrafish using customized zinc-finger nucleases.
Nat Protoc. 2009;4(12):1855-67 - PMID: 20010934 - PMCID: PMC2814337 - DOI: 10.1038/nprot.2009.209

Sebastiani P, Montano M, Puca A, Solovieff N, Kojima T, Wang MC, Melista E, Meltzer M, Fischer SE, Andersen S, Hartley SH, Sedgewick A, Arai Y, Bergman A, Barzilai N, Terry DF, Riva A, Anselmi CV, Malovini A, Kitamoto A, Sawabe M, Arai T, Gondo Y, Steinberg MH, Hirose N, Atzmon G, Ruvkun G, Baldwin CT, Perls TT

RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans.
PLoS One. 2009;4(12):e8210 - PMID: 20011587 - PMCID: PMC2788130 - DOI: 10.1371/journal.pone.0008210

Stanley SA, Hung DT

Toward a systems-level analysis of infection biology: a new method for conducting genetic screens in human cells.
Sci Transl Med. 2009;1(11):11ps13 - PMID: 20371455 - DOI: 10.1126/scitranslmed.3000550

Hett EC, Hung DT

Targeting multiple biofilm pathways.
Chem Biol. 2009;16(12):1216-8 - PMID: 20064430 - DOI: 10.1016/j.chembiol.2009.12.003

Brass AL, Huang IC, Benita Y, John SP, Krishnan MN, Feeley EM, Ryan BJ, Weyer JL, van der Weyden L, Fikrig E, Adams DJ, Xavier RJ, Farzan M, Elledge SJ

The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus.
Cell. 2009;139(7):1243-54 - PMID: 20064371 - PMCID: PMC2824905 - DOI: 10.1016/j.cell.2009.12.017

Voytas DF, Joung JK

Plant science. DNA binding made easy.
Science. 2009;326(5959):1491-2 - PMID: 20007890 - PMCID: PMC7814878 - DOI: 10.1126/science.1183604
Total: 2498