Publications for All Faculty

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Kaufmann BB, Hung DT

The fast track to multidrug resistance.
Mol Cell. 2010;37(3):297-8 - PMID: 20159549 - DOI: 10.1016/j.molcel.2010.01.027

Fitzgerald ML, Mujawar Z, Tamehiro N

ABC transporters, atherosclerosis and inflammation.
Atherosclerosis. 2010;211(2):361-70 - PMID: 20138281 - PMCID: PMC2888932 - DOI: 10.1016/j.atherosclerosis.2010.01.011

Estes KA, Dunbar TL, Powell JR, Ausubel FM, Troemel ER

bZIP transcription factor zip-2 mediates an early response to Pseudomonas aeruginosa infection in Caenorhabditis elegans.
Proc Natl Acad Sci U S A. 2010;107(5):2153-8 - PMID: 20133860 - PMCID: PMC2836710 - DOI: 10.1073/pnas.0914643107

Li JF, Li L, Sheen J

Protocol: a rapid and economical procedure for purification of plasmid or plant DNA with diverse applications in plant biology.
Plant Methods. 2010;6(1):1 - PMID: 20180960 - PMCID: PMC2829548 - DOI: 10.1186/1746-4811-6-1

Mosier MJ, Pham TN, Klein MB, Gibran NS, Arnoldo BD, Gamelli RL, Tompkins RG, Herndon DN

Early acute kidney injury predicts progressive renal dysfunction and higher mortality in severely burned adults.
J Burn Care Res. 2010;31(1):83-92 - PMID: 20061841 - PMCID: PMC3045668 - DOI: 10.1097/BCR.0b013e3181cb8c87

Kueng HJ, Manta C, Haiderer D, Leb VM, Schmetterer KG, Neunkirchner A, Byrne RA, Scheinecker C, Steinberger P, Seed B, Pickl WF

Fluorosomes: a convenient new reagent to detect and block multivalent and complex receptor-ligand interactions.
FASEB J. 2010;24(5):1572-82 - PMID: 20056716 - PMCID: PMC2879947 - DOI: 10.1096/fj.09-137281

Irazoqui JE, Urbach JM, Ausubel FM

Evolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebrates.
Nat Rev Immunol. 2010;10(1):47-58 - PMID: 20029447 - PMCID: PMC2965059 - DOI: 10.1038/nri2689

Huett A, Xavier RJ

Autophagy at the gut interface: mucosal responses to stress and the consequences for inflammatory bowel diseases.
Inflamm Bowel Dis. 2010;16(1):152-74 - PMID: 19575363 - PMCID: PMC3954538 - DOI: 10.1002/ibd.20991

Stewart CR, Stuart LM, Wilkinson K, van Gils JM, Deng J, Halle A, Rayner KJ, Boyer L, Zhong R, Frazier WA, Lacy-Hulbert A, El Khoury J, Golenbock DT, Moore KJ

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer.
Nat Immunol. 2010;11(2):155-61 - PMID: 20037584 - PMCID: PMC2809046 - DOI: 10.1038/ni.1836

Cho YH, Sheen J, Yoo SD

Low glucose uncouples hexokinase1-dependent sugar signaling from stress and defense hormone abscisic acid and C2H4 responses in Arabidopsis.
Plant Physiol. 2010;152(3):1180-2 - PMID: 20034964 - PMCID: PMC2832269 - DOI: 10.1104/pp.109.148957

Foley JE, Maeder ML, Pearlberg J, Joung JK, Peterson RT, Yeh JR

Targeted mutagenesis in zebrafish using customized zinc-finger nucleases.
Nat Protoc. 2009;4(12):1855-67 - PMID: 20010934 - PMCID: PMC2814337 - DOI: 10.1038/nprot.2009.209

Sebastiani P, Montano M, Puca A, Solovieff N, Kojima T, Wang MC, Melista E, Meltzer M, Fischer SE, Andersen S, Hartley SH, Sedgewick A, Arai Y, Bergman A, Barzilai N, Terry DF, Riva A, Anselmi CV, Malovini A, Kitamoto A, Sawabe M, Arai T, Gondo Y, Steinberg MH, Hirose N, Atzmon G, Ruvkun G, Baldwin CT, Perls TT

RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans.
PLoS One. 2009;4(12):e8210 - PMID: 20011587 - PMCID: PMC2788130 - DOI: 10.1371/journal.pone.0008210

Stanley SA, Hung DT

Toward a systems-level analysis of infection biology: a new method for conducting genetic screens in human cells.
Sci Transl Med. 2009;1(11):11ps13 - PMID: 20371455 - DOI: 10.1126/scitranslmed.3000550

Hett EC, Hung DT

Targeting multiple biofilm pathways.
Chem Biol. 2009;16(12):1216-8 - PMID: 20064430 - DOI: 10.1016/j.chembiol.2009.12.003

Brass AL, Huang IC, Benita Y, John SP, Krishnan MN, Feeley EM, Ryan BJ, Weyer JL, van der Weyden L, Fikrig E, Adams DJ, Xavier RJ, Farzan M, Elledge SJ

The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus.
Cell. 2009;139(7):1243-54 - PMID: 20064371 - PMCID: PMC2824905 - DOI: 10.1016/j.cell.2009.12.017

Voytas DF, Joung JK

Plant science. DNA binding made easy.
Science. 2009;326(5959):1491-2 - PMID: 20007890 - PMCID: PMC7814878 - DOI: 10.1126/science.1183604

Bruckner RJ, Mansy SS, Ricardo A, Mahadevan L, Szostak JW

Flip-flop-induced relaxation of bending energy: implications for membrane remodeling.
Biophys J. 2009;97(12):3113-22 - PMID: 20006948 - PMCID: PMC2793357 - DOI: 10.1016/j.bpj.2009.09.025

Fujii H, Chinnusamy V, Rodrigues A, Rubio S, Antoni R, Park SY, Cutler SR, Sheen J, Rodriguez PL, Zhu JK

In vitro reconstitution of an abscisic acid signalling pathway.
Nature. 2009;462(7273):660-4 - PMID: 19924127 - PMCID: PMC2803041 - DOI: 10.1038/nature08599

Imielinski M, Baldassano RN, Griffiths A, Russell RK, Annese V, Dubinsky M, Kugathasan S, Bradfield JP, Walters TD, Sleiman P, Kim CE, Muise A, Wang K, Glessner JT, Saeed S, Zhang H, Frackelton EC, Hou C, Flory JH, Otieno G, Chiavacci RM, Grundmeier R, Castro M, Latiano A, Dallapiccola B, Stempak J, Abrams DJ, Taylor K, McGovern D, , Silber G, Wrobel I, Quiros A, , Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmuda MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO, Murtha MT, Regueiro MD, Rotter JI, Schumm LP, Steinhart AH, Targan SR, Xavier RJ, , Libioulle C, Sandor C, Lathrop M, Belaiche J, Dewit O, Gut I, Heath S, Laukens D, Mni M, Rutgeerts P, Van Gossum A, Zelenika D, Franchimont D, Hugot JP, de Vos M, Vermeire S, Louis E, , , Cardon LR, Anderson CA, Drummond H, Nimmo E, Ahmad T, Prescott NJ, Onnie CM, Fisher SA, Marchini J, Ghori J, Bumpstead S, Gwillam R, Tremelling M, Delukas P, Mansfield J, Jewell D, Satsangi J, Mathew CG, Parkes M, Georges M, Daly MJ, Heyman MB, Ferry GD, Kirschner B, Lee J, Essers J, Grand R, Stephens M, Levine A, Piccoli D, Van Limbergen J, Cucchiara S, Monos DS, Guthery SL, Denson L, Wilson DC, Grant SF, Daly M, Silverberg MS, Satsangi J, Hakonarson H

Common variants at five new loci associated with early-onset inflammatory bowel disease.
Nat Genet. 2009;41(12):1335-40 - PMID: 19915574 - PMCID: PMC3267927 - DOI: 10.1038/ng.489

Spandidos A, Wang X, Wang H, Seed B

PrimerBank: a resource of human and mouse PCR primer pairs for gene expression detection and quantification.
Nucleic Acids Res. 2010;38(Database issue):D792-9 - PMID: 19906719 - PMCID: PMC2808898 - DOI: 10.1093/nar/gkp1005

Jarvik T, Smillie C, Groisman EA, Ochman H

Short-term signatures of evolutionary change in the Salmonella enterica serovar typhimurium 14028 genome.
J Bacteriol. 2010;192(2):560-7 - PMID: 19897643 - PMCID: PMC2805332 - DOI: 10.1128/JB.01233-09

O'Rourke EJ, Soukas AA, Carr CE, Ruvkun G

C. elegans major fats are stored in vesicles distinct from lysosome-related organelles.
Cell Metab. 2009;10(5):430-5 - PMID: 19883620 - PMCID: PMC2921818 - DOI: 10.1016/j.cmet.2009.10.002

Heath RJ, Xavier RJ

Autophagy, immunity and human disease.
Curr Opin Gastroenterol. 2009;25(6):512-20 - PMID: 19826372 - PMCID: PMC2849745 - DOI: 10.1097/MOG.0b013e32833104f1

Yagi H, Parekkadan B, Suganuma K, Soto-Gutierrez A, Tompkins RG, Tilles AW, Yarmush ML

Long-term superior performance of a stem cell/hepatocyte device for the treatment of acute liver failure.
Tissue Eng Part A. 2009;15(11):3377-88 - PMID: 19397469 - PMCID: PMC2792056 - DOI: 10.1089/ten.TEA.2008.0681

Lv B, Xu B, Feng Y, Peng K, Xu G, Du J, Zhang L, Zhang W, Zhang T, Zhu L, Ding H, Sheng Z, Welihinda A, Seed B, Chen Y

Exploration of O-spiroketal C-arylglucosides as novel and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors.
Bioorg Med Chem Lett. 2009;19(24):6877-81 - PMID: 19896374 - DOI: 10.1016/j.bmcl.2009.10.088
Total: 2489