Publications for All Faculty

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Bruckner RJ, Mansy SS, Ricardo A, Mahadevan L, Szostak JW

Flip-flop-induced relaxation of bending energy: implications for membrane remodeling.

Biophys J. 2009;97(12):3113-22 - PMID: 20006948 - PMCID: PMC2793357 - DOI: 10.1016/j.bpj.2009.09.025
Fujii H, Chinnusamy V, Rodrigues A, Rubio S, Antoni R, Park SY, Cutler SR, Sheen J, Rodriguez PL, Zhu JK

In vitro reconstitution of an abscisic acid signalling pathway.

Nature. 2009;462(7273):660-4 - PMID: 19924127 - PMCID: PMC2803041 - DOI: 10.1038/nature08599
Imielinski M, Baldassano RN, Griffiths A, Russell RK, Annese V, Dubinsky M, Kugathasan S, Bradfield JP, Walters TD, Sleiman P, Kim CE, Muise A, Wang K, Glessner JT, Saeed S, Zhang H, Frackelton EC, Hou C, Flory JH, Otieno G, Chiavacci RM, Grundmeier R, Castro M, Latiano A, Dallapiccola B, Stempak J, Abrams DJ, Taylor K, McGovern D, , Silber G, Wrobel I, Quiros A, , Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmuda MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO, Murtha MT, Regueiro MD, Rotter JI, Schumm LP, Steinhart AH, Targan SR, Xavier RJ, , Libioulle C, Sandor C, Lathrop M, Belaiche J, Dewit O, Gut I, Heath S, Laukens D, Mni M, Rutgeerts P, Van Gossum A, Zelenika D, Franchimont D, Hugot JP, de Vos M, Vermeire S, Louis E, , , Cardon LR, Anderson CA, Drummond H, Nimmo E, Ahmad T, Prescott NJ, Onnie CM, Fisher SA, Marchini J, Ghori J, Bumpstead S, Gwillam R, Tremelling M, Delukas P, Mansfield J, Jewell D, Satsangi J, Mathew CG, Parkes M, Georges M, Daly MJ, Heyman MB, Ferry GD, Kirschner B, Lee J, Essers J, Grand R, Stephens M, Levine A, Piccoli D, Van Limbergen J, Cucchiara S, Monos DS, Guthery SL, Denson L, Wilson DC, Grant SF, Daly M, Silverberg MS, Satsangi J, Hakonarson H

Common variants at five new loci associated with early-onset inflammatory bowel disease.

Nat Genet. 2009;41(12):1335-40 - PMID: 19915574 - PMCID: PMC3267927 - DOI: 10.1038/ng.489
Spandidos A, Wang X, Wang H, Seed B

PrimerBank: a resource of human and mouse PCR primer pairs for gene expression detection and quantification.

Nucleic Acids Res. 2010;38(Database issue):D792-9 - PMID: 19906719 - PMCID: PMC2808898 - DOI: 10.1093/nar/gkp1005
Jarvik T, Smillie C, Groisman EA, Ochman H

Short-term signatures of evolutionary change in the Salmonella enterica serovar typhimurium 14028 genome.

J Bacteriol. 2010;192(2):560-7 - PMID: 19897643 - PMCID: PMC2805332 - DOI: 10.1128/JB.01233-09
O'Rourke EJ, Soukas AA, Carr CE, Ruvkun G

C. elegans major fats are stored in vesicles distinct from lysosome-related organelles.

Cell Metab. 2009;10(5):430-5 - PMID: 19883620 - PMCID: PMC2921818 - DOI: 10.1016/j.cmet.2009.10.002
Heath RJ, Xavier RJ

Autophagy, immunity and human disease.

Curr Opin Gastroenterol. 2009;25(6):512-20 - PMID: 19826372 - PMCID: PMC2849745 - DOI: 10.1097/MOG.0b013e32833104f1
Yagi H, Parekkadan B, Suganuma K, Soto-Gutierrez A, Tompkins RG, Tilles AW, Yarmush ML

Long-term superior performance of a stem cell/hepatocyte device for the treatment of acute liver failure.

Tissue Eng Part A. 2009;15(11):3377-88 - PMID: 19397469 - PMCID: PMC2792056 - DOI: 10.1089/ten.TEA.2008.0681
Lv B, Xu B, Feng Y, Peng K, Xu G, Du J, Zhang L, Zhang W, Zhang T, Zhu L, Ding H, Sheng Z, Welihinda A, Seed B, Chen Y

Exploration of O-spiroketal C-arylglucosides as novel and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors.

Bioorg Med Chem Lett. 2009;19(24):6877-81 - PMID: 19896374 - DOI: 10.1016/j.bmcl.2009.10.088
Maslowski KM, Vieira AT, Ng A, Kranich J, Sierro F, Yu D, Schilter HC, Rolph MS, Mackay F, Artis D, Xavier RJ, Teixeira MM, Mackay CR

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43.

Nature. 2009;461(7268):1282-6 - PMID: 19865172 - PMCID: PMC3256734 - DOI: 10.1038/nature08530
Schrum JP, Ricardo A, Krishnamurthy M, Blain JC, Szostak JW

Efficient and rapid template-directed nucleic acid copying using 2'-amino-2',3'-dideoxyribonucleoside-5'-phosphorimidazolide monomers.

J Am Chem Soc. 2009;131(40):14560-70 - PMID: 19757789 - PMCID: PMC2759813 - DOI: 10.1021/ja906557v
Cobb JP, Moore EE, Hayden DL, Minei JP, Cuschieri J, Yang J, Li Q, Lin N, Brownstein BH, Hennessy L, Mason PH, Schierding WS, Dixon DJ, Tompkins RG, Warren HS, Schoenfeld DA, Maier RV

Validation of the riboleukogram to detect ventilator-associated pneumonia after severe injury.

Ann Surg. 2009;250(4):531-9 - PMID: 19730236 - PMCID: PMC3047595 - DOI: 10.1097/SLA.0b013e3181b8fbd5
Lu XM, Hamrahi VF, Tompkins RG, Fischman AJ

Effect of insulin levels on the phosphorylation of specific amino acid residues in IRS-1: implications for burn-induced insulin resistance.

Int J Mol Med. 2009;24(4):531-8 - PMID: 19724894 - PMCID: PMC4084762 - DOI: 10.3892/ijmm_00000262
Stoddard FJ, Sorrentino EA, Ceranoglu TA, Saxe G, Murphy JM, Drake JE, Ronfeldt H, White GW, Kagan J, Snidman N, Sheridan RL, Tompkins RG

Preliminary evidence for the effects of morphine on posttraumatic stress disorder symptoms in one- to four-year-olds with burns.

J Burn Care Res. 2009;30(5):836-43 - PMID: 19692914 - DOI: 10.1097/BCR.0b013e3181b48102
Maeder ML, Thibodeau-Beganny S, Sander JD, Voytas DF, Joung JK

Oligomerized pool engineering (OPEN): an 'open-source' protocol for making customized zinc-finger arrays.

Nat Protoc. 2009;4(10):1471-501 - PMID: 19798082 - PMCID: PMC2858690 - DOI: 10.1038/nprot.2009.98
Okoli I, Coleman JJ, Tampakakis E, Tempakakis E, An WF, Holson E, Wagner F, Conery AL, Larkins-Ford J, Wu G, Stern A, Ausubel FM, Mylonakis E

Identification of antifungal compounds active against Candida albicans using an improved high-throughput Caenorhabditis elegans assay.

PLoS One. 2009;4(9):e7025 - PMID: 19750012 - PMCID: PMC2737148 - DOI: 10.1371/journal.pone.0007025
Lapaquette P, Glasser AL, Huett A, Xavier RJ, Darfeuille-Michaud A

Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly.

Cell Microbiol. 2010;12(1):99-113 - PMID: 19747213 - PMCID: PMC3743084 - DOI: 10.1111/j.1462-5822.2009.01381.x
Mansy SS, Szostak JW

Reconstructing the emergence of cellular life through the synthesis of model protocells.

Cold Spring Harb Symp Quant Biol. 2009;74:47-54 - PMID: 19734203 - DOI: 10.1101/sqb.2009.74.014
Ricardo A, Szostak JW

Origin of life on earth.

Sci Am. 2009;301(3):54-61 - PMID: 19708528 - DOI: 10.1038/scientificamerican0909-54
Lin S, Horning DP, Szostak JW, Chaput JC

Conformational analysis of DNA repair intermediates by time-resolved fluorescence spectroscopy.

J Phys Chem A. 2009;113(35):9585-7 - PMID: 19673467 - PMCID: PMC2733762 - DOI: 10.1021/jp906746w
Stanley SA, Hung DT

Chemical tools for dissecting bacterial physiology and virulence.

Biochemistry. 2009;48(37):8776-86 - PMID: 19653697 - DOI: 10.1021/bi9009083
Tzika AA, Mintzopoulos D, Mindrinos M, Zhang J, Rahme LG, Tompkins RG

Microarray analysis suggests that burn injury results in mitochondrial dysfunction in human skeletal muscle.

Int J Mol Med. 2009;24(3):387-92 - PMID: 19639232 - PMCID: PMC3207251 - DOI: 10.3892/ijmm_00000244
M Freeman, Consultant editor, 4th edition. Buckley, Rita

What to do about high cholesterol

President and Fellows of Harvard College. Harvard Health Publications. 2009;:ePub
MW Freeman

Approach to the patient with hypercholesterolemia. In: Goroll A, May L, Mulley A, eds

Primary Care Medicine, 6th Edition. 2009;:ePub
Haydock GS and MW Freeman

Screening for hyperlipidemia. In: Goroll A and Mulley A, eds.

Primary Care Medicine, 6th Edition. 2009;:ePub
Total: 2473