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Gopalan S, Ausubel FM

A high throughput amenable Arabidopsis-P. aeruginosa system reveals a rewired regulatory module and the utility to identify potent anti-infectives.
PLoS One. 2011;6(1):e16381 - PMID: 21283656 - PMCID: PMC3025032 - DOI: 10.1371/journal.pone.0016381

Zhang C, Montgomery TA, Gabel HW, Fischer SE, Phillips CM, Fahlgren N, Sullivan CM, Carrington JC, Ruvkun G

mut-16 and other mutator class genes modulate 22G and 26G siRNA pathways in Caenorhabditis elegans.
Proc Natl Acad Sci U S A. 2011;108(4):1201-8 - PMID: 21245313 - PMCID: PMC3029761 - DOI: 10.1073/pnas.1018695108

Wang MC, Min W, Freudiger CW, Ruvkun G, Xie XS

RNAi screening for fat regulatory genes with SRS microscopy.
Nat Methods. 2011;8(2):135-8 - PMID: 21240281 - PMCID: PMC3061290 - DOI: 10.1038/nmeth.1556

Rossin EJ, Lage K, Raychaudhuri S, Xavier RJ, Tatar D, Benita Y, , Cotsapas C, Daly MJ

Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology.
PLoS Genet. 2011;7(1):e1001273 - PMID: 21249183 - PMCID: PMC3020935 - DOI: 10.1371/journal.pgen.1001273

Mosier MJ, Pham TN, Klein MB, Gibran NS, Arnoldo BD, Gamelli RL, Tompkins RG, Herndon DN

Early enteral nutrition in burns: compliance with guidelines and associated outcomes in a multicenter study.
J Burn Care Res. 2011;32(1):104-9 - PMID: 21116188 - PMCID: PMC3850279 - DOI: 10.1097/BCR.0b013e318204b3be

Zhang W, Welihinda A, Mechanic J, Ding H, Zhu L, Lu Y, Deng Z, Sheng Z, Lv B, Chen Y, Roberge JY, Seed B, Wang YX

EGT1442, a potent and selective SGLT2 inhibitor, attenuates blood glucose and HbA(1c) levels in db/db mice and prolongs the survival of stroke-prone rats.
Pharmacol Res. 2011;63(4):284-93 - PMID: 21215314 - DOI: 10.1016/j.phrs.2011.01.001

Tam JM, Castro CE, Heath RJ, Cardenas ML, Xavier RJ, Lang MJ, Vyas JM

Control and manipulation of pathogens with an optical trap for live cell imaging of intercellular interactions.
PLoS One. 2010;5(12):e15215 - PMID: 21217821 - PMCID: PMC3013098 - DOI: 10.1371/journal.pone.0015215

Sander JD, Dahlborg EJ, Goodwin MJ, Cade L, Zhang F, Cifuentes D, Curtin SJ, Blackburn JS, Thibodeau-Beganny S, Qi Y, Pierick CJ, Hoffman E, Maeder ML, Khayter C, Reyon D, Dobbs D, Langenau DM, Stupar RM, Giraldez AJ, Voytas DF, Peterson RT, Yeh JR, Joung JK

Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA).
Nat Methods. 2011;8(1):67-9 - PMID: 21151135 - PMCID: PMC3018472 - DOI: 10.1038/nmeth.1542

Beffa DC, Fischman AJ, Fagan SP, Hamrahi VF, Paul KW, Kaneki M, Yu YM, Tompkins RG, Carter EA

Simvastatin treatment improves survival in a murine model of burn sepsis: Role of interleukin 6.
Burns. 2011;37(2):222-6 - PMID: 21145172 - PMCID: PMC4085785 - DOI: 10.1016/j.burns.2010.10.010

Wu X, Ruvkun G

Cancer. Germ cell genes and cancer.
Science. 2010;330(6012):1761-2 - PMID: 21205660 - DOI: 10.1126/science.1200772

Kuballa P, Xavier RJ

Failure and exploitation of autophagy in human pathologies-cellular integrity between inflammation, infection, and cell survival.
Semin Immunopathol. 2010;32(4):319-22 - PMID: 21107575 - DOI: 10.1007/s00281-010-0229-5

Prelack K, Yu YM, Dylewski M, Lydon M, Sheridan RL, Tompkins RG

The contribution of muscle to whole-body protein turnover throughout the course of burn injury in children.
J Burn Care Res. 2010;31(6):942-8 - PMID: 21105320 - PMCID: PMC4084779 - DOI: 10.1097/BCR.0b013e3181f938e1

Acharya M, Mukhopadhyay S, Païdassi H, Jamil T, Chow C, Kissler S, Stuart LM, Hynes RO, Lacy-Hulbert A

av Integrin expression by DCs is required for Th17 cell differentiation and development of experimental autoimmune encephalomyelitis in mice.
J Clin Invest. 2010;120(12):4445-52 - PMID: 21099114 - PMCID: PMC2993596 - DOI: 10.1172/JCI43796

Whiteman NK, Groen SC, Chevasco D, Bear A, Beckwith N, Gregory TR, Denoux C, Mammarella N, Ausubel FM, Pierce NE

Mining the plant-herbivore interface with a leafmining Drosophila of Arabidopsis.
Mol Ecol. 2011;20(5):995-1014 - PMID: 21073583 - PMCID: PMC3062943 - DOI: 10.1111/j.1365-294X.2010.04901.x

Butler KL, Goverman J, Ma H, Fischman A, Yu YM, Bilodeau M, Rad AM, Bonab AA, Tompkins RG, Fagan SP

Stem cells and burns: review and therapeutic implications.
J Burn Care Res. 2010;31(6):874-81 - PMID: 20859216 - DOI: 10.1097/BCR.0b013e3181f9353a

Sander JD, Reyon D, Maeder ML, Foley JE, Thibodeau-Beganny S, Li X, Regan MR, Dahlborg EJ, Goodwin MJ, Fu F, Voytas DF, Joung JK, Dobbs D

Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences.
BMC Bioinformatics. 2010;11:543 - PMID: 21044337 - PMCID: PMC3098093 - DOI: 10.1186/1471-2105-11-543

Powner MW, Sutherland JD, Szostak JW

Chemoselective multicomponent one-pot assembly of purine precursors in water.
J Am Chem Soc. 2010;132(46):16677-88 - PMID: 21043502 - PMCID: PMC2984373 - DOI: 10.1021/ja108197s

Riley BE, Kaiser SE, Shaler TA, Ng AC, Hara T, Hipp MS, Lage K, Xavier RJ, Ryu KY, Taguchi K, Yamamoto M, Tanaka K, Mizushima N, Komatsu M, Kopito RR

Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection.
J Cell Biol. 2010;191(3):537-52 - PMID: 21041446 - PMCID: PMC3003313 - DOI: 10.1083/jcb.201005012

Gardet A, Benita Y, Li C, Sands BE, Ballester I, Stevens C, Korzenik JR, Rioux JD, Daly MJ, Xavier RJ, Podolsky DK

LRRK2 is involved in the IFN-gamma response and host response to pathogens.
J Immunol. 2010;185(9):5577-85 - PMID: 20921534 - PMCID: PMC3156100 - DOI: 10.4049/jimmunol.1000548

Szostak JW

DNA ends: just the beginning (Nobel lecture).
Angew Chem Int Ed Engl. 2010;49(41):7386-404 - PMID: 20818632 - DOI: 10.1002/anie.201000635

Sheen J

Discover and connect cellular signaling.
Plant Physiol. 2010;154(2):562-6 - PMID: 20921185 - PMCID: PMC2949017 - DOI: 10.1104/pp.110.161364

Raviv TR, Ljosa V, Conery AL, Ausubel FM, Carpenter AE, Golland P, Wählby C

Morphology-guided graph search for untangling objects: C. elegans analysis.
Med Image Comput Comput Assist Interv. 2010;13(Pt 3):634-41 - PMID: 20879454 - PMCID: PMC3050593 - DOI: 10.1007/978-3-642-15711-0_79

Hirota SA, Ng J, Lueng A, Khajah M, Parhar K, Li Y, Lam V, Potentier MS, Ng K, Bawa M, McCafferty DM, Rioux KP, Ghosh S, Xavier RJ, Colgan SP, Tschopp J, Muruve D, MacDonald JA, Beck PL

NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis.
Inflamm Bowel Dis. 2011;17(6):1359-72 - PMID: 20872834 - PMCID: PMC3026862 - DOI: 10.1002/ibd.21478

Mujawar Z, Tamehiro N, Grant A, Sviridov D, Bukrinsky M, Fitzgerald ML

Mutation of the ATP cassette binding transporter A1 (ABCA1) C-terminus disrupts HIV-1 Nef binding but does not block the Nef enhancement of ABCA1 protein degradation.
Biochemistry. 2010;49(38):8338-49 - PMID: 20731376 - PMCID: PMC2943568 - DOI: 10.1021/bi100466q

Qian WJ, Petritis BO, Kaushal A, Finnerty CC, Jeschke MG, Monroe ME, Moore RJ, Schepmoes AA, Xiao W, Moldawer LL, Davis RW, Tompkins RG, Herndon DN, Camp DG, Smith RD,

Plasma proteome response to severe burn injury revealed by 18O-labeled "universal" reference-based quantitative proteomics.
J Proteome Res. 2010;9(9):4779-89 - PMID: 20698492 - PMCID: PMC2945297 - DOI: 10.1021/pr1005026
Total: 2512