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Szostak JW

DNA ends: just the beginning (Nobel lecture).

Angew Chem Int Ed Engl. 2010;49(41):7386-404 - PMID: 20818632 - DOI: 10.1002/anie.201000635
Sheen J

Discover and connect cellular signaling.

Plant Physiol. 2010;154(2):562-6 - PMID: 20921185 - PMCID: PMC2949017 - DOI: 10.1104/pp.110.161364
Raviv TR, Ljosa V, Conery AL, Ausubel FM, Carpenter AE, Golland P, Wählby C

Morphology-guided graph search for untangling objects: C. elegans analysis.

Med Image Comput Comput Assist Interv. 2010;13(Pt 3):634-41 - PMID: 20879454 - PMCID: PMC3050593 - DOI: 10.1007/978-3-642-15711-0_79
Hirota SA, Ng J, Lueng A, Khajah M, Parhar K, Li Y, Lam V, Potentier MS, Ng K, Bawa M, McCafferty DM, Rioux KP, Ghosh S, Xavier RJ, Colgan SP, Tschopp J, Muruve D, MacDonald JA, Beck PL

NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis.

Inflamm Bowel Dis. 2011;17(6):1359-72 - PMID: 20872834 - PMCID: PMC3026862 - DOI: 10.1002/ibd.21478
Mujawar Z, Tamehiro N, Grant A, Sviridov D, Bukrinsky M, Fitzgerald ML

Mutation of the ATP cassette binding transporter A1 (ABCA1) C-terminus disrupts HIV-1 Nef binding but does not block the Nef enhancement of ABCA1 protein degradation.

Biochemistry. 2010;49(38):8338-49 - PMID: 20731376 - PMCID: PMC2943568 - DOI: 10.1021/bi100466q
Qian WJ, Petritis BO, Kaushal A, Finnerty CC, Jeschke MG, Monroe ME, Moore RJ, Schepmoes AA, Xiao W, Moldawer LL, Davis RW, Tompkins RG, Herndon DN, Camp DG, Smith RD,

Plasma proteome response to severe burn injury revealed by 18O-labeled "universal" reference-based quantitative proteomics.

J Proteome Res. 2010;9(9):4779-89 - PMID: 20698492 - PMCID: PMC2945297 - DOI: 10.1021/pr1005026
Bonab AA, Carter EA, Paul K, Kaneki M, Yu YM, Tompkins RG, Fischman AJ

Effect of simvastatin on burn-induced alterations in tissue specific glucose metabolism: implications for burn associated insulin resistance.

Int J Mol Med. 2010;26(3):311-6 - PMID: 20664945 - PMCID: PMC4090513
Smillie C, Garcillán-Barcia MP, Francia MV, Rocha EP, de la Cruz F

Mobility of plasmids.

Microbiol Mol Biol Rev. 2010;74(3):434-52 - PMID: 20805406 - PMCID: PMC2937521 - DOI: 10.1128/MMBR.00020-10
Kotz KT, Xiao W, Miller-Graziano C, Qian WJ, Russom A, Warner EA, Moldawer LL, De A, Bankey PE, Petritis BO, Camp DG, Rosenbach AE, Goverman J, Fagan SP, Brownstein BH, Irimia D, Xu W, Wilhelmy J, Mindrinos MN, Smith RD, Davis RW, Tompkins RG, Toner M,

Clinical microfluidics for neutrophil genomics and proteomics.

Nat Med. 2010;16(9):1042-7 - PMID: 20802500 - PMCID: PMC3136804 - DOI: 10.1038/nm.2205
Bekpen C, Xavier RJ, Eichler EE

Human IRGM gene "to be or not to be".

Semin Immunopathol. 2010;32(4):437-44 - PMID: 20737271 - DOI: 10.1007/s00281-010-0224-x
Söllü C, Pars K, Cornu TI, Thibodeau-Beganny S, Maeder ML, Joung JK, Heilbronn R, Cathomen T

Autonomous zinc-finger nuclease pairs for targeted chromosomal deletion.

Nucleic Acids Res. 2010;38(22):8269-76 - PMID: 20716517 - PMCID: PMC3001086 - DOI: 10.1093/nar/gkq720
Thibodeau-Beganny S, Maeder ML, Joung JK

Engineering single Cys2His2 zinc finger domains using a bacterial cell-based two-hybrid selection system.

Methods Mol Biol. 2010;649:31-50 - PMID: 20680826 - DOI: 10.1007/978-1-60761-753-2_2
Elenko MP, Szostak JW, van Oijen AM

Single-molecule binding experiments on long time scales.

Rev Sci Instrum. 2010;81(8):083705 - PMID: 20815611 - DOI: 10.1063/1.3473936
Asztalos BF, Mujawar Z, Morrow MP, Grant A, Pushkarsky T, Wanke C, Shannon R, Geyer M, Kirchhoff F, Sviridov D, Fitzgerald ML, Bukrinsky M, Mansfield KG

Circulating Nef induces dyslipidemia in simian immunodeficiency virus-infected macaques by suppressing cholesterol efflux.

J Infect Dis. 2010;202(4):614-23 - PMID: 20617930 - PMCID: PMC2932757 - DOI: 10.1086/654817
Butler KL, Ambravaneswaran V, Agrawal N, Bilodeau M, Toner M, Tompkins RG, Fagan S, Irimia D

Burn injury reduces neutrophil directional migration speed in microfluidic devices.

PLoS One. 2010;5(7):e11921 - PMID: 20689600 - PMCID: PMC2912851 - DOI: 10.1371/journal.pone.0011921
Yagi H, Soto-Gutierrez A, Navarro-Alvarez N, Nahmias Y, Goldwasser Y, Kitagawa Y, Tilles AW, Tompkins RG, Parekkadan B, Yarmush ML

Reactive bone marrow stromal cells attenuate systemic inflammation via sTNFR1.

Mol Ther. 2010;18(10):1857-64 - PMID: 20664529 - PMCID: PMC2951565 - DOI: 10.1038/mt.2010.155
Lipinski MM, Zheng B, Lu T, Yan Z, Py BF, Ng A, Xavier RJ, Li C, Yankner BA, Scherzer CR, Yuan J

Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease.

Proc Natl Acad Sci U S A. 2010;107(32):14164-9 - PMID: 20660724 - PMCID: PMC2922576 - DOI: 10.1073/pnas.1009485107
Yoon JC, Ng A, Kim BH, Bianco A, Xavier RJ, Elledge SJ

Wnt signaling regulates mitochondrial physiology and insulin sensitivity.

Genes Dev. 2010;24(14):1507-18 - PMID: 20634317 - PMCID: PMC2904941 - DOI: 10.1101/gad.1924910
Irazoqui JE, Troemel ER, Feinbaum RL, Luhachack LG, Cezairliyan BO, Ausubel FM

Distinct pathogenesis and host responses during infection of C. elegans by P. aeruginosa and S. aureus.

PLoS Pathog. 2010;6:e1000982 - PMID: 20617181 - PMCID: PMC2895663 - DOI: 10.1371/journal.ppat.1000982
Huett A, Goel G, Xavier RJ

A systems biology viewpoint on autophagy in health and disease.

Curr Opin Gastroenterol. 2010;26(4):302-9 - PMID: 20571384 - DOI: 10.1097/MOG.0b013e32833ae2ed
Ng AC, Eisenberg JM, Heath RJ, Huett A, Robinson CM, Nau GJ, Xavier RJ

Human leucine-rich repeat proteins: a genome-wide bioinformatic categorization and functional analysis in innate immunity.

Proc Natl Acad Sci U S A. 2011;108 Suppl 1:4631-8 - PMID: 20616063 - PMCID: PMC3063585 - DOI: 10.1073/pnas.1000093107
Kim H, Seed B

The transcription factor MafB antagonizes antiviral responses by blocking recruitment of coactivators to the transcription factor IRF3.

Nat Immunol. 2010;11(8):743-50 - PMID: 20581830 - PMCID: PMC3050627 - DOI: 10.1038/ni.1897
Yagi H, Soto-Gutierrez A, Kitagawa Y, Tilles AW, Tompkins RG, Yarmush ML

Bone marrow mesenchymal stromal cells attenuate organ injury induced by LPS and burn.

Cell Transplant. 2010;19(6):823-30 - PMID: 20573305 - PMCID: PMC2957544 - DOI: 10.3727/096368910X508942
Mashima R, Honda K, Yang Y, Morita Y, Inoue A, Arimura S, Nishina H, Ema H, Nakauchi H, Seed B, Oda H, Yamanashi Y

Mice lacking Dok-1, Dok-2, and Dok-3 succumb to aggressive histiocytic sarcoma.

Lab Invest. 2010;90(9):1357-64 - PMID: 20548287 - DOI: 10.1038/labinvest.2010.121
Yagi H, Soto-Gutierrez A, Parekkadan B, Kitagawa Y, Tompkins RG, Kobayashi N, Yarmush ML

Mesenchymal stem cells: Mechanisms of immunomodulation and homing.

Cell Transplant. 2010;19(6):667-79 - PMID: 20525442 - PMCID: PMC2957533 - DOI: 10.3727/096368910X508762
Total: 2468