Publications for All Faculty

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Xu W, Seok J, Mindrinos MN, Schweitzer AC, Jiang H, Wilhelmy J, Clark TA, Kapur K, Xing Y, Faham M, Storey JD, Moldawer LL, Maier RV, Tompkins RG, Wong WH, Davis RW, Xiao W,

Human transcriptome array for high-throughput clinical studies.

Proc Natl Acad Sci U S A. 2011;108(9):3707-12 - PMID: 21317363 - PMCID: PMC3048146 - DOI: 10.1073/pnas.1019753108
Anderson CA, Boucher G, Lees CW, Franke A, D'Amato M, Taylor KD, Lee JC, Goyette P, Imielinski M, Latiano A, Lagacé C, Scott R, Amininejad L, Bumpstead S, Baidoo L, Baldassano RN, Barclay M, Bayless TM, Brand S, Büning C, Colombel JF, Denson LA, De Vos M, Dubinsky M, Edwards C, Ellinghaus D, Fehrmann RS, Floyd JA, Florin T, Franchimont D, Franke L, Georges M, Glas J, Glazer NL, Guthery SL, Haritunians T, Hayward NK, Hugot JP, Jobin G, Laukens D, Lawrance I, Lémann M, Levine A, Libioulle C, Louis E, McGovern DP, Milla M, Montgomery GW, Morley KI, Mowat C, Ng A, Newman W, Ophoff RA, Papi L, Palmieri O, Peyrin-Biroulet L, Panés J, Phillips A, Prescott NJ, Proctor DD, Roberts R, Russell R, Rutgeerts P, Sanderson J, Sans M, Schumm P, Seibold F, Sharma Y, Simms LA, Seielstad M, Steinhart AH, Targan SR, van den Berg LH, Vatn M, Verspaget H, Walters T, Wijmenga C, Wilson DC, Westra HJ, Xavier RJ, Zhao ZZ, Ponsioen CY, Andersen V, Torkvist L, Gazouli M, Anagnou NP, Karlsen TH, Kupcinskas L, Sventoraityte J, Mansfield JC, Kugathasan S, Silverberg MS, Halfvarson J, Rotter JI, Mathew CG, Griffiths AM, Gearry R, Ahmad T, Brant SR, Chamaillard M, Satsangi J, Cho JH, Schreiber S, Daly MJ, Barrett JC, Parkes M, Annese V, Hakonarson H, Radford-Smith G, Duerr RH, Vermeire S, Weersma RK, Rioux JD

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

Nat Genet. 2011;43(3):246-52 - PMID: 21297633 - PMCID: PMC3084597 - DOI: 10.1038/ng.764
Shen CA, Fagan S, Fischman AJ, Carter EE, Chai JK, Lu XM, Yu YM, Tompkins RG

Effects of glucagon-like peptide 1 on glycemia control and its metabolic consequence after severe thermal injury--studies in an animal model.

Surgery. 2011;149(5):635-44 - PMID: 21295809 - PMCID: PMC3079016 - DOI: 10.1016/j.surg.2010.11.017
Rosenbach AE, Koria P, Goverman J, Kotz KT, Gupta A, Yu M, Fagan SP, Irimia D, Tompkins RG

Microfluidics for T- lymphocyte cell separation and inflammation monitoring in burn patients.

Clin Transl Sci. 2011;4(1):63-8 - PMID: 21348958 - PMCID: PMC3057059 - DOI: 10.1111/j.1752-8062.2010.00255.x
Gomez JE, Clatworthy A, Hung DT

Probing bacterial pathogenesis with genetics, genomics, and chemical biology: past, present, and future approaches.

Crit Rev Biochem Mol Biol. 2011;46(1):41-66 - PMID: 21250782 - DOI: 10.3109/10409238.2010.538663
Reyon D, Kirkpatrick JR, Sander JD, Zhang F, Voytas DF, Joung JK, Dobbs D, Coffman CR

ZFNGenome: a comprehensive resource for locating zinc finger nuclease target sites in model organisms.

BMC Genomics. 2011;12:83 - PMID: 21276248 - PMCID: PMC3042413 - DOI: 10.1186/1471-2164-12-83
Gopalan S, Ausubel FM

A high throughput amenable Arabidopsis-P. aeruginosa system reveals a rewired regulatory module and the utility to identify potent anti-infectives.

PLoS One. 2011;6(1):e16381 - PMID: 21283656 - PMCID: PMC3025032 - DOI: 10.1371/journal.pone.0016381
Zhang C, Montgomery TA, Gabel HW, Fischer SE, Phillips CM, Fahlgren N, Sullivan CM, Carrington JC, Ruvkun G

mut-16 and other mutator class genes modulate 22G and 26G siRNA pathways in Caenorhabditis elegans.

Proc Natl Acad Sci U S A. 2011;108(4):1201-8 - PMID: 21245313 - PMCID: PMC3029761 - DOI: 10.1073/pnas.1018695108
Wang MC, Min W, Freudiger CW, Ruvkun G, Xie XS

RNAi screening for fat regulatory genes with SRS microscopy.

Nat Methods. 2011;8(2):135-8 - PMID: 21240281 - PMCID: PMC3061290 - DOI: 10.1038/nmeth.1556
Rossin EJ, Lage K, Raychaudhuri S, Xavier RJ, Tatar D, Benita Y, , Cotsapas C, Daly MJ

Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology.

PLoS Genet. 2011;7(1):e1001273 - PMID: 21249183 - PMCID: PMC3020935 - DOI: 10.1371/journal.pgen.1001273
Mosier MJ, Pham TN, Klein MB, Gibran NS, Arnoldo BD, Gamelli RL, Tompkins RG, Herndon DN

Early enteral nutrition in burns: compliance with guidelines and associated outcomes in a multicenter study.

J Burn Care Res. 2011;32(1):104-9 - PMID: 21116188 - PMCID: PMC3850279 - DOI: 10.1097/BCR.0b013e318204b3be
Zhang W, Welihinda A, Mechanic J, Ding H, Zhu L, Lu Y, Deng Z, Sheng Z, Lv B, Chen Y, Roberge JY, Seed B, Wang YX

EGT1442, a potent and selective SGLT2 inhibitor, attenuates blood glucose and HbA(1c) levels in db/db mice and prolongs the survival of stroke-prone rats.

Pharmacol Res. 2011;63(4):284-93 - PMID: 21215314 - DOI: 10.1016/j.phrs.2011.01.001
Tam JM, Castro CE, Heath RJ, Cardenas ML, Xavier RJ, Lang MJ, Vyas JM

Control and manipulation of pathogens with an optical trap for live cell imaging of intercellular interactions.

PLoS One. 2010;5(12):e15215 - PMID: 21217821 - PMCID: PMC3013098 - DOI: 10.1371/journal.pone.0015215
Sander JD, Dahlborg EJ, Goodwin MJ, Cade L, Zhang F, Cifuentes D, Curtin SJ, Blackburn JS, Thibodeau-Beganny S, Qi Y, Pierick CJ, Hoffman E, Maeder ML, Khayter C, Reyon D, Dobbs D, Langenau DM, Stupar RM, Giraldez AJ, Voytas DF, Peterson RT, Yeh JR, Joung JK

Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA).

Nat Methods. 2011;8(1):67-9 - PMID: 21151135 - PMCID: PMC3018472 - DOI: 10.1038/nmeth.1542
Beffa DC, Fischman AJ, Fagan SP, Hamrahi VF, Paul KW, Kaneki M, Yu YM, Tompkins RG, Carter EA

Simvastatin treatment improves survival in a murine model of burn sepsis: Role of interleukin 6.

Burns. 2011;37(2):222-6 - PMID: 21145172 - PMCID: PMC4085785 - DOI: 10.1016/j.burns.2010.10.010
Wu X, Ruvkun G

Cancer. Germ cell genes and cancer.

Science. 2010;330(6012):1761-2 - PMID: 21205660 - DOI: 10.1126/science.1200772
Kuballa P, Xavier RJ

Failure and exploitation of autophagy in human pathologies-cellular integrity between inflammation, infection, and cell survival.

Semin Immunopathol. 2010;32(4):319-22 - PMID: 21107575 - DOI: 10.1007/s00281-010-0229-5
Prelack K, Yu YM, Dylewski M, Lydon M, Sheridan RL, Tompkins RG

The contribution of muscle to whole-body protein turnover throughout the course of burn injury in children.

J Burn Care Res. 2010;31(6):942-8 - PMID: 21105320 - PMCID: PMC4084779 - DOI: 10.1097/BCR.0b013e3181f938e1
Acharya M, Mukhopadhyay S, Païdassi H, Jamil T, Chow C, Kissler S, Stuart LM, Hynes RO, Lacy-Hulbert A

av Integrin expression by DCs is required for Th17 cell differentiation and development of experimental autoimmune encephalomyelitis in mice.

J Clin Invest. 2010;120(12):4445-52 - PMID: 21099114 - PMCID: PMC2993596 - DOI: 10.1172/JCI43796
Whiteman NK, Groen SC, Chevasco D, Bear A, Beckwith N, Gregory TR, Denoux C, Mammarella N, Ausubel FM, Pierce NE

Mining the plant-herbivore interface with a leafmining Drosophila of Arabidopsis.

Mol Ecol. 2011;20(5):995-1014 - PMID: 21073583 - PMCID: PMC3062943 - DOI: 10.1111/j.1365-294X.2010.04901.x
Butler KL, Goverman J, Ma H, Fischman A, Yu YM, Bilodeau M, Rad AM, Bonab AA, Tompkins RG, Fagan SP

Stem cells and burns: review and therapeutic implications.

J Burn Care Res. 2010;31(6):874-81 - PMID: 20859216 - DOI: 10.1097/BCR.0b013e3181f9353a
Sander JD, Reyon D, Maeder ML, Foley JE, Thibodeau-Beganny S, Li X, Regan MR, Dahlborg EJ, Goodwin MJ, Fu F, Voytas DF, Joung JK, Dobbs D

Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences.

BMC Bioinformatics. 2010;11:543 - PMID: 21044337 - PMCID: PMC3098093 - DOI: 10.1186/1471-2105-11-543
Powner MW, Sutherland JD, Szostak JW

Chemoselective multicomponent one-pot assembly of purine precursors in water.

J Am Chem Soc. 2010;132(46):16677-88 - PMID: 21043502 - PMCID: PMC2984373 - DOI: 10.1021/ja108197s
Riley BE, Kaiser SE, Shaler TA, Ng AC, Hara T, Hipp MS, Lage K, Xavier RJ, Ryu KY, Taguchi K, Yamamoto M, Tanaka K, Mizushima N, Komatsu M, Kopito RR

Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection.

J Cell Biol. 2010;191(3):537-52 - PMID: 21041446 - PMCID: PMC3003313 - DOI: 10.1083/jcb.201005012
Gardet A, Benita Y, Li C, Sands BE, Ballester I, Stevens C, Korzenik JR, Rioux JD, Daly MJ, Xavier RJ, Podolsky DK

LRRK2 is involved in the IFN-gamma response and host response to pathogens.

J Immunol. 2010;185(9):5577-85 - PMID: 20921534 - PMCID: PMC3156100 - DOI: 10.4049/jimmunol.1000548
Total: 2468