Publications for All Faculty

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Moore KJ, Freeman MW

Targeting Innate Immunity for CV Benefit.

Drug Discov Today Ther Strateg. 2011;5(1):15-23 - PMID: 19430537 - PMCID: PMC2678718 - DOI: 10.1016/j.ddstr.2008.05.007
Païdassi H, Acharya M, Zhang A, Mukhopadhyay S, Kwon M, Chow C, Stuart LM, Savill J, Lacy-Hulbert A

Preferential expression of integrin avb8 promotes generation of regulatory T cells by mouse CD103+ dendritic cells.

Gastroenterology. 2011;141(5):1813-20 - PMID: 21745448 - PMCID: PMC3202651 - DOI: 10.1053/j.gastro.2011.06.076
Hill MN, McLaughlin RJ, Pan B, Fitzgerald ML, Roberts CJ, Lee TT, Karatsoreos IN, Mackie K, Viau V, Pickel VM, McEwen BS, Liu QS, Gorzalka BB, Hillard CJ

Recruitment of prefrontal cortical endocannabinoid signaling by glucocorticoids contributes to termination of the stress response.

J Neurosci. 2011;31(29):10506-15 - PMID: 21775596 - PMCID: PMC3179266 - DOI: 10.1523/JNEUROSCI.0496-11.2011
Tena G, Boudsocq M, Sheen J

Protein kinase signaling networks in plant innate immunity.

Curr Opin Plant Biol. 2011;14(5):519-29 - PMID: 21704551 - PMCID: PMC3191242 - DOI: 10.1016/j.pbi.2011.05.006
Tanaka N, Abe-Dohmae S, Iwamoto N, Fitzgerald ML, Yokoyama S

HMG-CoA reductase inhibitors enhance phagocytosis by upregulating ATP-binding cassette transporter A7.

Atherosclerosis. 2011;217(2):407-14 - PMID: 21762915 - PMCID: PMC3150192 - DOI: 10.1016/j.atherosclerosis.2011.06.031
Pukkila-Worley R, Ausubel FM, Mylonakis E

Candida albicans infection of Caenorhabditis elegans induces antifungal immune defenses.

PLoS Pathog. 2011;7(6):e1002074 - PMID: 21731485 - PMCID: PMC3121877 - DOI: 10.1371/journal.ppat.1002074
Xu B, Feng Y, Cheng H, Song Y, Lv B, Wu Y, Wang C, Li S, Xu M, Du J, Peng K, Dong J, Zhang W, Zhang T, Zhu L, Ding H, Sheng Z, Welihinda A, Roberge JY, Seed B, Chen Y

C-aryl glucosides substituted at the 4'-position as potent and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes.

Bioorg Med Chem Lett. 2011;21(15):4465-70 - PMID: 21737266 - DOI: 10.1016/j.bmcl.2011.06.032
Khor B, Gardet A, Xavier RJ

Genetics and pathogenesis of inflammatory bowel disease.

Nature. 2011;474(7351):307-17 - PMID: 21677747 - PMCID: PMC3204665 - DOI: 10.1038/nature10209
Hipp J, Flotte T, Monaco J, Cheng J, Madabhushi A, Yagi Y, Rodriguez-Canales J, Emmert-Buck M, Dugan MC, Hewitt S, Toner M, Tompkins RG, Lucas D, Gilbertson JR, Balis UJ

Computer aided diagnostic tools aim to empower rather than replace pathologists: Lessons learned from computational chess.

J Pathol Inform. 2011;2:25 - PMID: 21773056 - PMCID: PMC3132993 - DOI: 10.4103/2153-3539.82050
Russo BC, Horzempa J, O'Dee DM, Schmitt DM, Brown MJ, Carlson PE, Xavier RJ, Nau GJ

A Francisella tularensis locus required for spermine responsiveness is necessary for virulence.

Infect Immun. 2011;79(9):3665-76 - PMID: 21670171 - PMCID: PMC3165480 - DOI: 10.1128/IAI.00135-11
Wang S, Villablanca EJ, De Calisto J, Gomes DC, Nguyen DD, Mizoguchi E, Kagan JC, Reinecker HC, Hacohen N, Nagler C, Xavier RJ, Rossi-Bergmann B, Chen YB, Blomhoff R, Snapper SB, Mora JR

MyD88-dependent TLR1/2 signals educate dendritic cells with gut-specific imprinting properties.

J Immunol. 2011;187(1):141-50 - PMID: 21646294 - PMCID: PMC3119749 - DOI: 10.4049/jimmunol.1003740
Freeman MW, Dervan AP

The path from bench to bedside: considerations before starting the journey.

J Investig Med. 2011;59(5):746-51 - PMID: 21441830 - PMCID: PMC4255460 - DOI: 10.2310/JIM.0b013e3182160d70
Danna CH, Millet YA, Koller T, Han SW, Bent AF, Ronald PC, Ausubel FM

The Arabidopsis flagellin receptor FLS2 mediates the perception of Xanthomonas Ax21 secreted peptides.

Proc Natl Acad Sci U S A. 2011;108(22):9286-91 - PMID: 21576467 - PMCID: PMC3107323 - DOI: 10.1073/pnas.1106366108
Le LP, Nielsen GP, Rosenberg AE, Thomas D, Batten JM, Deshpande V, Schwab J, Duan Z, Xavier RJ, Hornicek FJ, Iafrate AJ

Recurrent chromosomal copy number alterations in sporadic chordomas.

PLoS One. 2011;6(5):e18846 - PMID: 21602918 - PMCID: PMC3094331 - DOI: 10.1371/journal.pone.0018846
Carter EA, Bonab AA, Hamrahi V, Pitman J, Winter D, Macintosh LJ, Cyr EM, Paul K, Yerxa J, Jung W, Tompkins RG, Fischman AJ

Effects of burn injury, cold stress and cutaneous wound injury on the morphology and energy metabolism of murine brown adipose tissue (BAT) in vivo.

Life Sci. 2011;89(3-4):78-85 - PMID: 21565200 - PMCID: PMC4081480 - DOI: 10.1016/j.lfs.2011.04.014
Seebeck FP, Ricardo A, Szostak JW

Artificial lantipeptides from in vitro translations.

Chem Commun (Camb). 2011;47(21):6141-3 - PMID: 21528125 - DOI: 10.1039/c0cc05663d
Chand NS, Lee JS, Clatworthy AE, Golas AJ, Smith RS, Hung DT

The sensor kinase KinB regulates virulence in acute Pseudomonas aeruginosa infection.

J Bacteriol. 2011;193(12):2989-99 - PMID: 21515773 - PMCID: PMC3133189 - DOI: 10.1128/JB.01546-10
Lee H, Chah OK, Sheen J

Stem-cell-triggered immunity through CLV3p-FLS2 signalling.

Nature. 2011;473(7347):376-9 - PMID: 21499263 - PMCID: PMC3098311 - DOI: 10.1038/nature09958
Heath RJ, Leong JM, Visegrády B, Machesky LM, Xavier RJ

Bacterial and host determinants of MAL activation upon EPEC infection: the roles of Tir, ABRA, and FLRT3.

PLoS Pathog. 2011;7(4):e1001332 - PMID: 21490959 - PMCID: PMC3072376 - DOI: 10.1371/journal.ppat.1001332
Curtin SJ, Zhang F, Sander JD, Haun WJ, Starker C, Baltes NJ, Reyon D, Dahlborg EJ, Goodwin MJ, Coffman AP, Dobbs D, Joung JK, Voytas DF, Stupar RM

Targeted mutagenesis of duplicated genes in soybean with zinc-finger nucleases.

Plant Physiol. 2011;156(2):466-73 - PMID: 21464476 - PMCID: PMC3177250 - DOI: 10.1104/pp.111.172981
Stappenbeck TS, Rioux JD, Mizoguchi A, Saitoh T, Huett A, Darfeuille-Michaud A, Wileman T, Mizushima N, Carding S, Akira S, Parkes M, Xavier RJ

Crohn disease: a current perspective on genetics, autophagy and immunity.

Autophagy. 2011;7(4):355-74 - PMID: 20729636 - PMCID: PMC3842289 - DOI: 10.4161/auto.7.2.13074
Fitzgerald ML, Lupica CR, Pickel VM

Decreased parvalbumin immunoreactivity in the cortex and striatum of mice lacking the CB1 receptor.

Synapse. 2011;65(8):827-31 - PMID: 21445945 - PMCID: PMC3107909 - DOI: 10.1002/syn.20911
Budin I, Szostak JW

Physical effects underlying the transition from primitive to modern cell membranes.

Proc Natl Acad Sci U S A. 2011;108(13):5249-54 - PMID: 21402937 - PMCID: PMC3069173 - DOI: 10.1073/pnas.1100498108
Subtelny AO, Hartman MC, Szostak JW

Optimal codon choice can improve the efficiency and fidelity of N-methyl amino acid incorporation into peptides by in-vitro translation.

Angew Chem Int Ed Engl. 2011;50(14):3164-7 - PMID: 21381166 - PMCID: PMC4006073 - DOI: 10.1002/anie.201007686
Berthiaume F, Tompkins RG, Yarmush ML

Isolation and long-term maintenance of adult rat hepatocytes in culture.

Methods Mol Med. 2011;18:447-56 - PMID: 21370195 - DOI: 10.1385/0-89603-516-6:447
Total: 2470