Publications for All Faculty

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Merquiol E, Uzi D, Mueller T, Goldenberg D, Nahmias Y, Xavier RJ, Tirosh B, Shibolet O

HCV causes chronic endoplasmic reticulum stress leading to adaptation and interference with the unfolded protein response.

PLoS One. 2011;6(9):e24660 - PMID: 21949742 - PMCID: PMC3176279 - DOI: 10.1371/journal.pone.0024660
Warner EA, Kotz KT, Ungaro RF, Abouhamze AS, Lopez MC, Cuenca AG, Kelly-Scumpia KM, Moreno C, O'Malley KA, Lanz JD, Baker HV, Martin LC, Toner M, Tompkins RG, Efron PA, Moldawer LL

Microfluidics-based capture of human neutrophils for expression analysis in blood and bronchoalveolar lavage.

Lab Invest. 2011;91(12):1787-95 - PMID: 21931299 - PMCID: PMC3957199 - DOI: 10.1038/labinvest.2011.94
Sander JD, Yeh JR, Peterson RT, Joung JK

Engineering zinc finger nucleases for targeted mutagenesis of zebrafish.

Methods Cell Biol. 2011;104:51-8 - PMID: 21924156 - DOI: 10.1016/B978-0-12-374814-0.00003-3
Desai KH, Tan CS, Leek JT, Maier RV, Tompkins RG, Storey JD,

Dissecting inflammatory complications in critically injured patients by within-patient gene expression changes: a longitudinal clinical genomics study.

PLoS Med. 2011;8(9):e1001093 - PMID: 21931541 - PMCID: PMC3172280 - DOI: 10.1371/journal.pmed.1001093
Carter EA, Bonab AA, Paul K, Yerxa J, Tompkins RG, Fischman AJ

Association of heat production with 18F-FDG accumulation in murine brown adipose tissue after stress.

J Nucl Med. 2011;52(10):1616-20 - PMID: 21914754 - PMCID: PMC4082963 - DOI: 10.2967/jnumed.111.090175
Stoddard FJ, White GW, Kazis LE, Murphy JM, Sorrentino EA, Hinson M, Kim Stubbs T, Chan G, Sheridan RL, Palmieri T, Kagan R, Herndon D, Tompkins RG

Patterns of medication administration from 2001 to 2009 in the treatment of children with acute burn injuries: a multicenter study.

J Burn Care Res. 2011;32(5):519-28 - PMID: 21811176 - DOI: 10.1097/BCR.0b013e31822bef92
Ryan CM, Antoon A, Fagan SP, Goverman J, Lawlor D, Sheridan RL, Tompkins RG

Considerations for preparedness for a pediatric burn disaster.

J Burn Care Res. 2011;32(5):e165-6 - PMID: 21772149 - DOI: 10.1097/BCR.0b013e31822ac9a4
Lindquist S, Karitkina D, Langnaese K, Posevitz-Fejfar A, Schraven B, Xavier R, Seed B, Lindquist JA

Phosphoprotein associated with glycosphingolipid-enriched microdomains differentially modulates SRC kinase activity in brain maturation.

PLoS One. 2011;6(9):e23978 - PMID: 21915273 - PMCID: PMC3167820 - DOI: 10.1371/journal.pone.0023978
Cuenca AG, Maier RV, Cuschieri J, Moore EE, Moldawer LL, Tompkins RG,

The Glue Grant experience: characterizing the post injury genomic response.

Eur J Trauma Emerg Surg. 2011;37(6):549-58 - PMID: 26815465 - PMCID: PMC6541206 - DOI: 10.1007/s00068-011-0148-8
Zhao Y, Alonso C, Ballester I, Song JH, Chang SY, Guleng B, Arihiro S, Murray PJ, Xavier R, Kobayashi KS, Reinecker HC

Control of NOD2 and Rip2-dependent innate immune activation by GEF-H1.

Inflamm Bowel Dis. 2012;18(4):603-12 - PMID: 21887730 - PMCID: PMC3594873 - DOI: 10.1002/ibd.21851
Ng A, Xavier RJ

Leucine-rich repeat (LRR) proteins: integrators of pattern recognition and signaling in immunity.

Autophagy. 2011;7(9):1082-4 - PMID: 21606681 - PMCID: PMC3901792 - DOI: 10.4161/auto.7.9.16464
MW Freeman

Lipoprotein Metabolism and the Treatment of Lipid Disorders, Chapter 42. In: DeGroot LJ and JL Jameson, eds

Endocrinology, 6th edition. 2010;:ePub
Hamel LP, Benchabane M, Nicole MC, Major IT, Morency MJ, Pelletier G, Beaudoin N, Sheen J, Séguin A

Stress-responsive mitogen-activated protein kinases interact with the EAR motif of a poplar zinc finger protein and mediate its degradation through the 26S proteasome.

Plant Physiol. 2011;157(3):1379-93 - PMID: 21873571 - PMCID: PMC3252155 - DOI: 10.1104/pp.111.178343
Yang W, Yamada M, Tamura Y, Chang K, Mao J, Zou L, Feng Y, Kida K, Scherrer-Crosbie M, Chao W, Ichinose F, Yu YM, Fischman AJ, Tompkins RG, Yao S, Kaneki M

Farnesyltransferase inhibitor FTI-277 reduces mortality of septic mice along with improved bacterial clearance.

J Pharmacol Exp Ther. 2011;339(3):832-41 - PMID: 21873557 - PMCID: PMC3226365 - DOI: 10.1124/jpet.111.183558
Trevino SG, Zhang N, Elenko MP, Lupták A, Szostak JW

Evolution of functional nucleic acids in the presence of nonheritable backbone heterogeneity.

Proc Natl Acad Sci U S A. 2011;108(33):13492-7 - PMID: 21825162 - PMCID: PMC3158193 - DOI: 10.1073/pnas.1107113108
Pattanayak V, Ramirez CL, Joung JK, Liu DR

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection.

Nat Methods. 2011;8(9):765-70 - PMID: 21822273 - PMCID: PMC3164905 - DOI: 10.1038/nmeth.1670
Sander JD, Cade L, Khayter C, Reyon D, Peterson RT, Joung JK, Yeh JR

Targeted gene disruption in somatic zebrafish cells using engineered TALENs.

Nat Biotechnol. 2011;29(8):697-8 - PMID: 21822241 - PMCID: PMC3154023 - DOI: 10.1038/nbt.1934
Tamayo AG, Slater L, Taylor-Parker J, Bharti A, Harrison R, Hung DT, Murphy JR

GRP78(BiP) facilitates the cytosolic delivery of anthrax lethal factor (LF) in vivo and functions as an unfoldase in vitro.

Mol Microbiol. 2011;81(5):1390-401 - PMID: 21797942 - PMCID: PMC4041151 - DOI: 10.1111/j.1365-2958.2011.07770.x
Tam JM, Castro CE, Heath RJ, Mansour MK, Cardenas ML, Xavier RJ, Lang MJ, Vyas JM

Use of an optical trap for study of host-pathogen interactions for dynamic live cell imaging.

J Vis Exp. 2011;(53):ePub - PMID: 21841755 - PMCID: PMC3197446 - DOI: 10.3791/3123
Rahman SH, Maeder ML, Joung JK, Cathomen T

Zinc-finger nucleases for somatic gene therapy: the next frontier.

Hum Gene Ther. 2011;22(8):925-33 - PMID: 21631241 - PMCID: PMC3159524 - DOI: 10.1089/hum.2011.087
Lee J, Hirsh AS, Wittner BS, Maeder ML, Singavarapu R, Lang M, Janarthanan S, McDermott U, Yajnik V, Ramaswamy S, Joung JK, Sgroi DC

Induction of stable drug resistance in human breast cancer cells using a combinatorial zinc finger transcription factor library.

PLoS One. 2011;6(7):e21112 - PMID: 21818254 - PMCID: PMC3139592 - DOI: 10.1371/journal.pone.0021112
Carter EA, Bonab AA, Goverman J, Paul K, Yerxa J, Tompkins RG, Fischman AJ

Evaluation of the antioxidant peptide SS31 for treatment of burn-induced insulin resistance.

Int J Mol Med. 2011;28(4):589-94 - PMID: 21805045 - PMCID: PMC4090514 - DOI: 10.3892/ijmm.2011.752
Moore KJ, Freeman MW

Targeting Innate Immunity for CV Benefit.

Drug Discov Today Ther Strateg. 2011;5(1):15-23 - PMID: 19430537 - PMCID: PMC2678718 - DOI: 10.1016/j.ddstr.2008.05.007
Païdassi H, Acharya M, Zhang A, Mukhopadhyay S, Kwon M, Chow C, Stuart LM, Savill J, Lacy-Hulbert A

Preferential expression of integrin avb8 promotes generation of regulatory T cells by mouse CD103+ dendritic cells.

Gastroenterology. 2011;141(5):1813-20 - PMID: 21745448 - PMCID: PMC3202651 - DOI: 10.1053/j.gastro.2011.06.076
Hill MN, McLaughlin RJ, Pan B, Fitzgerald ML, Roberts CJ, Lee TT, Karatsoreos IN, Mackie K, Viau V, Pickel VM, McEwen BS, Liu QS, Gorzalka BB, Hillard CJ

Recruitment of prefrontal cortical endocannabinoid signaling by glucocorticoids contributes to termination of the stress response.

J Neurosci. 2011;31(29):10506-15 - PMID: 21775596 - PMCID: PMC3179266 - DOI: 10.1523/JNEUROSCI.0496-11.2011
Total: 2467