Publications for All Faculty

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Duerr EM, Mizukami Y, Moriichi K, Gala M, Jo WS, Kikuchi H, Xavier RJ, Chung DC

ONCOGENIC KRAS REGULATES BMP4 EXPRESSION IN COLON CANCER CELL LINES.

Am J Physiol Gastrointest Liver Physiol. 2012;302(10):G1223-30 - PMID: 22383492 - PMCID: PMC3362092 - DOI: 10.1152/ajpgi.00047.2011
Ramirez CL, Certo MT, Mussolino C, Goodwin MJ, Cradick TJ, McCaffrey AP, Cathomen T, Scharenberg AM, Joung JK

Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects.

Nucleic Acids Res. 2012;40(12):5560-8 - PMID: 22373919 - PMCID: PMC3384306 - DOI: 10.1093/nar/gks179
O'Brien JA, Daudi A, Finch P, Butt VS, Whitelegge JP, Souda P, Ausubel FM, Bolwell GP

A Peroxidase-Dependent Apoplastic Oxidative Burst in Cultured Arabidopsis Cells Functions in MAMP-Elicited Defense.

Plant Physiol. 2012;158(4):2013-27 - PMID: 22319074 - PMCID: PMC3320203 - DOI: 10.1104/pp.111.190140
Grad YH, Lipsitch M, Feldgarden M, Arachchi HM, Cerqueira GC, Fitzgerald M, Godfrey P, Haas BJ, Murphy CI, Russ C, Sykes S, Walker BJ, Wortman JR, Young S, Zeng Q, Abouelleil A, Bochicchio J, Chauvin S, Desmet T, Gujja S, McCowan C, Montmayeur A, Steelman S, Frimodt-Møller J, Petersen AM, Struve C, Krogfelt KA, Bingen E, Weill FX, Lander ES, Nusbaum C, Birren BW, Hung DT, Hanage WP

Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011.

Proc Natl Acad Sci U S A. 2012;109(8):3065-70 - PMID: 22315421 - PMCID: PMC3286951 - DOI: 10.1073/pnas.1121491109
Zhang N, Zhang S, Szostak JW

Activated ribonucleotides undergo a sugar pucker switch upon binding to a single-stranded RNA template.

J Am Chem Soc. 2012;134(8):3691-4 - PMID: 22296305 - PMCID: PMC3448298 - DOI: 10.1021/ja212027q
Jeschke MG, Finnerty CC, Herndon DN, Song J, Boehning D, Tompkins RG, Baker HV, Gauglitz GG

Severe injury is associated with insulin resistance, endoplasmic reticulum stress response, and unfolded protein response.

Ann Surg. 2012;255(2):370-8 - PMID: 22241293 - PMCID: PMC3395076 - DOI: 10.1097/SLA.0b013e31823e76e7
Szostak JW

Attempts to define life do not help to understand the origin of life.

J Biomol Struct Dyn. 2012;29(4):599-600 - PMID: 22208251 - PMCID: PMC4208307 - DOI: 10.1080/073911012010524998
Tompkins RG

Survival of children with burn injuries.

Lancet. 2012;379(9820):983-4 - PMID: 22296811 - PMCID: PMC4019221 - DOI: 10.1016/S0140-6736(11)61626-7
Song J, Finnerty CC, Herndon DN, Kraft R, Boehning D, Brooks NC, Tompkins RG, Jeschke MG

Thermal Injury Activates eEF2k-Dependent eEF2 Pathway in Pediatric Patients.

JPEN J Parenter Enteral Nutr. 2012;36(5):596-602 - PMID: 22269896 - PMCID: PMC3580832 - DOI: 10.1177/0148607111422234
Wei SC, Rosenberg IM, Cao Z, Huett AS, Xavier RJ, Podolsky DK

Tribbles 2 (Trib2) is a novel regulator of toll-like receptor 5 signaling.

Inflamm Bowel Dis. 2012;18(5):877-88 - PMID: 22271508 - PMCID: PMC3881418 - DOI: 10.1002/ibd.22883
Cui HL, Grant A, Mukhamedova N, Pushkarsky T, Jennelle L, Dubrovsky L, Gaus K, Fitzgerald ML, Sviridov D, Bukrinsky M

HIV-1 Nef mobilizes lipid rafts in macrophages through a pathway that competes with ABCA1-dependent cholesterol efflux.

J Lipid Res. 2012;53(4):696-708 - PMID: 22262807 - PMCID: PMC3307646 - DOI: 10.1194/jlr.M023119
Gewurz BE, Towfic F, Mar JC, Shinners NP, Takasaki K, Zhao B, Cahir-McFarland ED, Quackenbush J, Xavier RJ, Kieff E

Genome-wide siRNA screen for mediators of NF-?B activation.

Proc Natl Acad Sci U S A. 2012;109(7):2467-72 - PMID: 22308454 - PMCID: PMC3289371 - DOI: 10.1073/pnas.1120542109
Daudi A, Cheng Z, O'Brien JA, Mammarella N, Khan S, Ausubel FM, Bolwell GP

The apoplastic oxidative burst peroxidase in Arabidopsis is a major component of pattern-triggered immunity.

Plant Cell. 2012;24(1):275-87 - PMID: 22247251 - PMCID: PMC3289579 - DOI: 10.1105/tpc.111.093039
Pukkila-Worley R, Ausubel FM

Immune defense mechanisms in the Caenorhabditis elegans intestinal epithelium.

Curr Opin Immunol. 2012;24(1):3-9 - PMID: 22236697 - PMCID: PMC3660727 - DOI: 10.1016/j.coi.2011.10.004
van Gils JM, Derby MC, Fernandes LR, Ramkhelawon B, Ray TD, Rayner KJ, Parathath S, Distel E, Feig JL, Alvarez-Leite JI, Rayner AJ, McDonald TO, O'Brien KD, Stuart LM, Fisher EA, Lacy-Hulbert A, Moore KJ

The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques.

Nat Immunol. 2012;13(2):136-43 - PMID: 22231519 - PMCID: PMC3262880 - DOI: 10.1038/ni.2205
Weber JM, Sheridan RL, Fagan S, Ryan CM, Pasternack MS, Tompkins RG

Incidence of Catheter-Associated Bloodstream Infection After Introduction of Minocycline and Rifampin Antimicrobial-Coated Catheters in a Pediatric Burn Population.

J Burn Care Res. 2012;33(4):539-43 - PMID: 22210071 - DOI: 10.1097/BCR.0b013e31823c4cd5
Zhou L, Kawate T, Liu X, Kim YB, Zhao Y, Feng G, Banerji J, Nash H, Whitehurst C, Jindal S, Siddiqui A, Seed B, Wolfe JL

STAT6 phosphorylation inhibitors block eotaxin-3 secretion in bronchial epithelial cells.

Bioorg Med Chem. 2012;20(2):750-8 - PMID: 22217933 - DOI: 10.1016/j.bmc.2011.12.006
Lu XM, Tompkins RG, Fischman AJ

SILAM for quantitative proteomics of liver Akt1/PKB? after burn injury.

Int J Mol Med. 2012;29(3):461-71 - PMID: 22179310 - PMCID: PMC3981641 - DOI: 10.3892/ijmm.2011.861
Lee J, Kim HR, Quinley C, Kim J, Gonzalez-Navajas J, Xavier R, Raz E

Autophagy suppresses interleukin-1? (IL-1?) signaling by activation of p62 degradation via lysosomal and proteasomal pathways.

J Biol Chem. 2012;287(6):4033-40 - PMID: 22167182 - PMCID: PMC3281713 - DOI: 10.1074/jbc.M111.280065
Wivagg CN, Hung DT

Resuscitation-promoting factors are required for ?-lactam tolerance and the permeability barrier in Mycobacterium tuberculosis.

Antimicrob Agents Chemother. 2012;56(3):1591-4 - PMID: 22155826 - PMCID: PMC3294900 - DOI: 10.1128/AAC.06027-11
Xiong Y, Sheen J

Rapamycin and glucose-target of rapamycin (TOR) protein signaling in plants.

J Biol Chem. 2012;287(4):2836-42 - PMID: 22134914 - PMCID: PMC3268441 - DOI: 10.1074/jbc.M111.300749
Orvedahl A, Sumpter R, Xiao G, Ng A, Zou Z, Tang Y, Narimatsu M, Gilpin C, Sun Q, Roth M, Forst CV, Wrana JL, Zhang YE, Luby-Phelps K, Xavier RJ, Xie Y, Levine B

Image-based genome-wide siRNA screen identifies selective autophagy factors.

Nature. 2011;480(7375):113-7 - PMID: 22020285 - PMCID: PMC3229641 - DOI: 10.1038/nature10546
Lee HY, Kaneki M, Andreas J, Tompkins RG, Martyn JA

Novel mitochondria-targeted antioxidant peptide ameliorates burn-induced apoptosis and endoplasmic reticulum stress in the skeletal muscle of mice.

Shock. 2011;36(6):580-5 - PMID: 21937949 - PMCID: PMC3230221 - DOI: 10.1097/SHK.0b013e3182366872
Duffy AM, Fitzgerald ML, Chan J, Robinson DC, Milner TA, Mackie K, Pickel VM

Acetylcholine ?7 nicotinic and dopamine D(2) receptors are targeted to many of the same postsynaptic dendrites and astrocytes in the rodent prefrontal cortex.

Synapse. 2011;65(12):1350-67 - PMID: 21858872 - PMCID: PMC3356922 - DOI: 10.1002/syn.20977
Boyer L, Paquette N, Silverman N, Stuart LM

Bacterial effectors: learning on the fly.

Adv Exp Med Biol. 2011;710:29-36 - PMID: 22127883 - PMCID: PMC3427734 - DOI: 10.1007/978-1-4419-5638-5_4
Total: 2467