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Ye R, Lin Z, Liu KH, Sheen J, Chen S

Dynamic Proximity Tagging in Living Plant Cells with Pupylation-Based Interaction Tagging.
Methods Mol Biol. 2023;2690:137-147 - PMID: 37450145 - DOI: 10.1007/978-1-0716-3327-4_14

Aitken HRM, Wright TH, Radakovic A, Szostak JW

Small-Molecule Organocatalysis Facilitates In Situ Nucleotide Activation and RNA Copying.
J Am Chem Soc. 2023;145(29):16142-16149 - PMID: 37431761 - PMCID: PMC10375519 - DOI: 10.1021/jacs.3c04635

Halvorsen YD, Conery AL, Lock JP, Zhou W, Freeman MW

Bexagliflozin as an adjunct to metformin for the treatment of type 2 diabetes in adults: A 24-week, randomized, double-blind, placebo-controlled trial.
Diabetes Obes Metab. 2023;25(10):2954-2962 - PMID: 37409573 - DOI: 10.1111/dom.15192

Xu J, Kong L, Oliver BA, Li B, Creasey EA, Guzman G, Schenone M, Carey KL, Carr SA, Graham DB, Deguine J, Xavier RJ

Constitutively active autophagy in macrophages dampens inflammation through metabolic and post-transcriptional regulation of cytokine production.
Cell Rep. 2023;42(7):112708 - PMID: 37392388 - PMCID: PMC10503440 - DOI: 10.1016/j.celrep.2023.112708

Strazar M, Park J, Abelin JG, Taylor HB, Pedersen TK, Plichta DR, Brown EM, Eraslan B, Hung YM, Ortiz K, Clauser KR, Carr SA, Xavier RJ, Graham DB

HLA-II immunopeptidome profiling and deep learning reveal features of antigenicity to inform antigen discovery.
Immunity. 2023;56(7):1681-1698.e13 - PMID: 37301199 - PMCID: PMC10519123 - DOI: 10.1016/j.immuni.2023.05.009

Zhang SJ, Lowe LA, Anees P, Krishnan Y, Fai TG, Szostak JW, Wang A

Passive endocytosis in model protocells.
Proc Natl Acad Sci U S A. 2023;120(24):e2221064120 - PMID: 37276401 - PMCID: PMC10268330 - DOI: 10.1073/pnas.2221064120

Ding D, Zhang SJ, Szostak JW

Enhanced nonenzymatic RNA copying with in-situ activation of short oligonucleotides.
Nucleic Acids Res. 2023;51(13):6528-6539 - PMID: 37247941 - PMCID: PMC10359593 - DOI: 10.1093/nar/gkad439

Kalam H, Chou CH, Kadoki M, Graham DB, Deguine J, Hung DT, Xavier RJ

Identification of host regulators of Mycobacterium tuberculosis phenotypes uncovers a role for the MMGT1-GPR156 lipid droplet axis in persistence.
Cell Host Microbe. 2023;31(6):978-992.e5 - PMID: 37269834 - PMCID: PMC10373099 - DOI: 10.1016/j.chom.2023.05.009

Fan Z, Deckel Y, Lowe LA, Loo DWK, Yomo T, Szostak JW, Nisler C, Wang A

Lipid Exchange Promotes Fusion of Model Protocells.
Small Methods. 2023;7(12):e2300126 - PMID: 37246261 - DOI: 10.1002/smtd.202300126

Graham DB, Xavier RJ

Conditioning of the immune system by the microbiome.
Trends Immunol. 2023;44(7):499-511 - PMID: 37236891 - DOI: 10.1016/j.it.2023.05.002

DasGupta S, Zhang SJ, Smela MP, Szostak JW

RNA-catalyzed RNA Ligation within Prebiotically Plausible Model Protocells.
Chemistry. 2023;29(43):e202301376 - PMID: 37216492 - DOI: 10.1002/chem.202301376

Johansen J, Atarashi K, Arai Y, Hirose N, Sørensen SJ, Vatanen T, Knip M, Honda K, Xavier RJ, Rasmussen S, Plichta DR

Centenarians have a diverse gut virome with the potential to modulate metabolism and promote healthy lifespan.
Nat Microbiol. 2023;8(6):1064-1078 - PMID: 37188814 - DOI: 10.1038/s41564-023-01370-6

Warnhoff K, Snoozy J, Breen PC, Ruvkun G

Hypoxia-inducible factor promotes cysteine homeostasis in Caenorhabditis elegans.
bioRxiv. 2023;:ePub - PMID: 37205365 - PMCID: PMC10187278 - DOI: 10.1101/2023.05.04.538701

Zhang SJ, Lowe LA, Anees P, Krishnan Y, Fai TG, Szostak JW, Wang A

Passive endocytosis in model protocells.
bioRxiv. 2023;:ePub - PMID: 37205531 - PMCID: PMC10187163 - DOI: 10.1101/2023.01.07.522792

Lee JWJ, Plichta DR, Asher S, Delsignore M, Jeong T, McGoldrick J, Staller K, Khalili H, Xavier RJ, Chung DC

Association of distinct microbial signatures with premalignant colorectal adenomas.
Cell Host Microbe. 2023;31(5):827-838.e3 - PMID: 37130517 - PMCID: PMC10477964 - DOI: 10.1016/j.chom.2023.04.007

Thakku SG, Lirette J, Murugesan K, Chen J, Theron G, Banaei N, Blainey PC, Gomez J, Wong SY, Hung DT

Genome-wide tiled detection of circulating Mycobacterium tuberculosis cell-free DNA using Cas13.
Nat Commun. 2023;14(1):1803 - PMID: 37002219 - PMCID: PMC10064635 - DOI: 10.1038/s41467-023-37183-8

Ding D, Zhou L, Mittal S, Szostak JW

Experimental Tests of the Virtual Circular Genome Model for Nonenzymatic RNA Replication.
J Am Chem Soc. 2023;145(13):7504-7515 - PMID: 36963403 - PMCID: PMC10080680 - DOI: 10.1021/jacs.3c00612

Huang XW, Pan W, Zhong MZ, Chhonker YS, Steele AD, Keohane CE, Mishra B, Felix Raj Lucas LO, Murry DJ, Ausubel FM, Wuest WM, Li CX, Mylonakis E

Biological Evaluation of the Antibacterial Retinoid CD437 in Cutibacterium acnes Infection.
Antimicrob Agents Chemother. 2023;67(4):e0167922 - PMID: 36943064 - PMCID: PMC10112217 - DOI: 10.1128/aac.01679-22

Halvorsen SC, Benita Y, Hopton M, Hoppe B, Gunnlaugsson HO, Korgaonkar P, Vanderburg CR, Nielsen GP, Trepanowski N, Cheah JH, Frosch MP, Schwab JH, Rosenberg AE, Hornicek FJ, Sassi S

Transcriptional Profiling Supports the Notochordal Origin of Chordoma and Its Dependence on a TGFΒ1-TBXT Network.
Am J Pathol. 2023;193(5):532-547 - PMID: 36804377 - DOI: 10.1016/j.ajpath.2023.01.014

Freeman MW, Bond M, Murphy B, Hui J, Isaacsohn J

Results From a Randomized, Open-Label, Crossover Study Evaluating the Effect of the Aldosterone Synthase Inhibitor Baxdrostat on the Pharmacokinetics of Metformin in Healthy Human Subjects.
Am J Cardiovasc Drugs. 2023;23(3):277-286 - PMID: 36790596 - PMCID: PMC9930700 - DOI: 10.1007/s40256-023-00572-x

Scheid JF, Eraslan B, Hudak A, Brown EM, Sergio D, Delorey TM, Phillips D, Lefkovith A, Jess AT, Duck LW, Elson CO, Vlamakis H, Plichta DR, Deguine J, Ananthakrishnan AN, Graham DB, Regev A, Xavier RJ

Remodeling of colon plasma cell repertoire within ulcerative colitis patients.
J Exp Med. 2023;220(4):ePub - PMID: 36752797 - PMCID: PMC9949229 - DOI: 10.1084/jem.20220538

Brown EM, Clardy J, Xavier RJ

Gut microbiome lipid metabolism and its impact on host physiology.
Cell Host Microbe. 2023;31(2):173-186 - PMID: 36758518 - PMCID: PMC10124142 - DOI: 10.1016/j.chom.2023.01.009

Ma P, Amemiya HM, He LL, Gandhi SJ, Nicol R, Bhattacharyya RP, Smillie CS, Hung DT

Bacterial droplet-based single-cell RNA-seq reveals antibiotic-associated heterogeneous cellular states.
Cell. 2023;186(4):877-891.e14 - PMID: 36708705 - PMCID: PMC10014032 - DOI: 10.1016/j.cell.2023.01.002

Kong L, Pokatayev V, Lefkovith A, Carter GT, Creasey EA, Krishna C, Subramanian S, Kochar B, Ashenberg O, Lau H, Ananthakrishnan AN, Graham DB, Deguine J, Xavier RJ

The landscape of immune dysregulation in Crohn's disease revealed through single-cell transcriptomic profiling in the ileum and colon.
Immunity. 2023;56(2):444-458.e5 - PMID: 36720220 - PMCID: PMC9957882 - DOI: 10.1016/j.immuni.2023.01.002

Vatanen T, Jabbar KS, Ruohtula T, Honkanen J, Avila-Pacheco J, Siljander H, Stražar M, Oikarinen S, Hyöty H, Ilonen J, Mitchell CM, Yassour M, Virtanen SM, Clish CB, Plichta DR, Vlamakis H, Knip M, Xavier RJ

Mobile genetic elements from the maternal microbiome shape infant gut microbial assembly and metabolism.
Cell. 2022;185(26):4921-4936.e15 - PMID: 36563663 - PMCID: PMC9869402 - DOI: 10.1016/j.cell.2022.11.023
Total: 2489