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Osborn MJ, Starker CG, McElroy AN, Webber BR, Riddle MJ, Xia L, Defeo AP, Gabriel R, Schmidt M, Von Kalle C, Carlson DF, Maeder ML, Joung JK, Wagner JE, Voytas DF, Blazar BR, Tolar J

TALEN-based Gene Correction for Epidermolysis Bullosa.
Mol Ther. 2013;21(6):1151-1159 - PMID: 23546300 - PMCID: PMC3677309 - DOI: 10.1038/mt.2013.56

Kirienko NV, Kirienko DR, Larkins-Ford J, Wählby C, Ruvkun G, Ausubel FM

Pseudomonas aeruginosa Disrupts Caenorhabditis elegans Iron Homeostasis, Causing a Hypoxic Response and Death.
Cell Host Microbe. 2013;13(4):406-16 - PMID: 23601103 - PMCID: PMC3641844 - DOI: 10.1016/j.chom.2013.03.003

Kirienko NV, Kirienko DR, Larkins-Ford J, Wählby C, Ruvkun G, Ausubel FM

Pseudomonas aeruginosa Disrupts Caenorhabditis elegans Iron Homeostasis, Causing a Hypoxic Response and Death.
Cell Host Microbe. 2013;13(4):406-16 - PMID: 23601103 - PMCID: PMC3641844 - DOI: 10.1016/j.chom.2013.03.003

Montgomery TA, Ruvkun G

MicroRNAs Visit the ER.
Cell. 2013;153(3):511-2 - PMID: 23622236 - DOI: 10.1016/j.cell.2013.04.014

Xiong Y, McCormack M, Li L, Hall Q, Xiang C, Sheen J

Glucose-TOR signalling reprograms the transcriptome and activates meristems.
Nature. 2013;496(7444):181-6 - PMID: 23542588 - PMCID: PMC4140196 - DOI: 10.1038/nature12030

Tannahill GM, Curtis AM, Adamik J, Palsson-McDermott EM, McGettrick AF, Goel G, Frezza C, Bernard NJ, Kelly B, Foley NH, Zheng L, Gardet A, Tong Z, Jany SS, Corr SC, Haneklaus M, Caffrey BE, Pierce K, Walmsley S, Beasley FC, Cummins E, Nizet V, Whyte M, Taylor CT, Lin H, Masters SL, Gottlieb E, Kelly VP, Clish C, Auron PE, Xavier RJ, O'Neill LA

Succinate is an inflammatory signal that induces IL-1? through HIF-1?.
Nature. 2013;496(7444):238-42 - PMID: 23535595 - PMCID: PMC4031686 - DOI: 10.1038/nature11986

Lupfer C, Thomas PG, Anand PK, Vogel P, Milasta S, Martinez J, Huang G, Green M, Kundu M, Chi H, Xavier RJ, Green DR, Lamkanfi M, Dinarello CA, Doherty PC, Kanneganti TD

Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection.
Nat Immunol. 2013;14(5):480-8 - PMID: 23525089 - PMCID: PMC3631456 - DOI: 10.1038/ni.2563

Righi V, Constantinou C, Mintzopoulos D, Khan N, Mupparaju SP, Rahme LG, Swartz HM, Szeto HH, Tompkins RG, Tzika AA

Mitochondria-targeted antioxidant promotes recovery of skeletal muscle mitochondrial function after burn trauma assessed by in vivo 31P nuclear magnetic resonance and electron paramagnetic resonance spectroscopy.
FASEB J. 2013;27(6):2521-30 - PMID: 23482635 - PMCID: PMC3659352 - DOI: 10.1096/fj.12-220764

Hosokawa S, Nagashima M, Maeyama Y, Koseki H, Yomogida K, Mehr C, Rutledge M, Greenfeld H, Kaneki M, Tompkins RG, Martyn JJ, Yasuhara SE

Efficacy of Phosphodiesterase 5 inhibitor on distant burn-induced muscle autophagy, microcirculation and survival rate.
Am J Physiol Endocrinol Metab. 2013;304(9):E922-33 - PMID: 23512808 - DOI: 10.1152/ajpendo.00078.2013

Watada S, Yu YM, Fischman AJ, Kurihara T, Shen CA, Tompkins RG, Fagan S

Evaluation of Intragastric Vs Intraperitoneal Glucose Tolerance Tests in the Evaluation of Insulin Resistance in a Rodent Model of Burn Injury and Glucagon-Like Polypeptide-1 Treatment.
J Burn Care Res. 2013;35(1):e66-72 - PMID: 23511296 - PMCID: PMC4053788 - DOI: 10.1097/BCR.0b013e31828a8ede

Finnerty CC, Jeschke MG, Qian WJ, Kaushal A, Xiao W, Liu T, Gritsenko MA, Moore RJ, Camp DG, Moldawer LL, Elson C, Schoenfeld D, Gamelli R, Gibran N, Klein M, Arnoldo B, Remick D, Smith RD, Davis R, Tompkins RG, Herndon DN,

Determination of Burn Patient Outcome by Large-Scale Quantitative Discovery Proteomics.
Crit Care Med. 2013;41(6):1421-1434 - PMID: 23507713 - PMCID: PMC3660437 - DOI: 10.1097/CCM.0b013e31827c072e

Djonovi? S, Urbach JM, Drenkard E, Bush J, Feinbaum R, Ausubel JL, Traficante D, Risech M, Kocks C, Fischbach MA, Priebe GP, Ausubel FM

Trehalose biosynthesis promotes Pseudomonas aeruginosa pathogenicity in plants.
PLoS Pathog. 2013;9(3):e1003217 - PMID: 23505373 - PMCID: PMC3591346 - DOI: 10.1371/journal.ppat.1003217

Gmyrek GB, Graham DB, Sandoval G, Blaufuss GS, Akilesh HM, Fujikawa K, Xavier RJ, Swat W

Polarity gene discs large homolog 1 regulates the generation of memory T cells.
Eur J Immunol. 2013;43(5):1185-94 - PMID: 23436244 - PMCID: PMC3894631 - DOI: 10.1002/eji.201142362

Kurihara T, Jones CN, Yu YM, Fischman AJ, Watada S, Tompkins RG, Fagan SP, Irimia D

Resolvin D2 restores neutrophil directionality and improves survival after burns.
FASEB J. 2013;27(6):2270-81 - PMID: 23430978 - PMCID: PMC3659356 - DOI: 10.1096/fj.12-219519

Sandoval GJ, Graham DB, Bhattacharya D, Sleckman BP, Xavier RJ, Swat W

Cutting Edge: cell-autonomous control of IL-7 response revealed in a novel stage of precursor B cells.
J Immunol. 2013;190(6):2485-9 - PMID: 23420891 - PMCID: PMC3649847 - DOI: 10.4049/jimmunol.1203208

Stuart LM, Paquette N, Boyer L

Effector-triggered versus pattern-triggered immunity: how animals sense pathogens.
Nat Rev Immunol. 2013;13(3):199-206 - PMID: 23411798 - PMCID: PMC4121468 - DOI: 10.1038/nri3398

Martin ES, Belmont PJ, Sinnamon MJ, Georgeon Richard L, Yuan J, Coffee EM, Roper J, Lee L, Heidari P, Lunt SY, Goel G, Ji C, Xie J, Xie T, Lamb J, Weinrich S, Vanarsdale TL, Bronson RT, Xavier RJ, Vander Heiden M, Kan JL, Mahmood U, Hung KE

Development of a Colon Cancer GEMM-Derived Orthotopic Transplant Model for Drug Discovery and Validation.
Clin Cancer Res. 2013;19(11):2929-40 - PMID: 23403635 - PMCID: PMC3951107 - DOI: 10.1158/1078-0432.CCR-12-2307

Seok J, Warren HS, Cuenca AG, Mindrinos MN, Baker HV, Xu W, Richards DR, McDonald-Smith GP, Gao H, Hennessy L, Finnerty CC, López CM, Honari S, Moore EE, Minei JP, Cuschieri J, Bankey PE, Johnson JL, Sperry J, Nathens AB, Billiar TR, West MA, Jeschke MG, Klein MB, Gamelli RL, Gibran NS, Brownstein BH, Miller-Graziano C, Calvano SE, Mason PH, Cobb JP, Rahme LG, Lowry SF, Maier RV, Moldawer LL, Herndon DN, Davis RW, Xiao W, Tompkins RG,

Genomic responses in mouse models poorly mimic human inflammatory diseases.
Proc Natl Acad Sci U S A. 2013;110(9):3507-12 - PMID: 23401516 - PMCID: PMC3587220 - DOI: 10.1073/pnas.1222878110

Maeder ML, Linder SJ, Reyon D, Angstman JF, Fu Y, Sander JD, Joung JK

Robust, synergistic regulation of human gene expression using TALE activators.
Nat Methods. 2013;10(3):243-5 - PMID: 23396285 - PMCID: PMC3584229 - DOI: 10.1038/nmeth.2366

Kirby A, Gnirke A, Jaffe DB, Barešová V, Pochet N, Blumenstiel B, Ye C, Aird D, Stevens C, Robinson JT, Cabili MN, Gat-Viks I, Kelliher E, Daza R, Defelice M, H?lková H, Sovová J, Vylet'al P, Antignac C, Guttman M, Handsaker RE, Perrin D, Steelman S, Sigurdsson S, Scheinman SJ, Sougnez C, Cibulskis K, Parkin M, Green T, Rossin E, Zody MC, Xavier RJ, Pollak MR, Alper SL, Lindblad-Toh K, Gabriel S, Hart PS, Regev A, Nusbaum C, Kmoch S, Bleyer AJ, Lander ES, Daly MJ

Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing.
Nat Genet. 2013;45(3):299-303 - PMID: 23396133 - PMCID: PMC3901305 - DOI: 10.1038/ng.2543

Fukumoto T, Kano A, Ohtani K, Inoue M, Yoshihara A, Izumori K, Tajima S, Shigematsu Y, Tanaka K, Ohkouchi T, Ishida Y, Nishizawa Y, Tada Y, Ichimura K, Gomi K, Yoo SD, Sheen J, Akimitsu K

Phosphorylation of D-allose by hexokinase involved in regulation of OsABF1 expression for growth inhibition in Oryza sativa L.
Planta. 2013;237(5):1379-91 - PMID: 23397192 - DOI: 10.1007/s00425-013-1853-9

O'Rourke EJ, Kuballa P, Xavier R, Ruvkun G

?-6 Polyunsaturated fatty acids extend life span through the activation of autophagy.
Genes Dev. 2013;27(4):429-40 - PMID: 23392608 - PMCID: PMC3589559 - DOI: 10.1101/gad.205294.112

Buffen K, Oosting M, Mennens S, Anand PK, Plantinga TS, Sturm P, van de Veerdonk FL, van der Meer JW, Xavier RJ, Kannegati TD, Netea MG, Joosten LA

Autophagy modulates Borrelia burgdorferi-induced production of interleukin-1? (IL-1?).
J Biol Chem. 2013;288(12):8658-66 - PMID: 23386602 - PMCID: PMC3605684 - DOI: 10.1074/jbc.M112.412841

Cuenca AG, Gentile LF, Lopez MC, Ungaro R, Liu H, Xiao W, Seok J, Mindrinos MN, Ang D, Ozrazgat Baslanti T, Bihorac A, Efron PA, Cuschieri J, Warren HS, Tompkins RG, Maier RV, Baker HV, Moldawer LL,

Development of a Genomic Metric That Can Be Rapidly Used to Predict Clinical Outcome in Severely Injured Trauma Patients.
Crit Care Med. 2013;41(5):1175-1185 - PMID: 23388514 - PMCID: PMC3652285 - DOI: 10.1097/CCM.0b013e318277131c

Tremblay JP, Xiao X, Aartsma-Rus A, Barbas C, Blau HM, Bogdanove AJ, Boycott K, Braun S, Breakefield XO, Bueren JA, Buschmann M, Byrne BJ, Calos M, Cathomen T, Chamberlain J, Chuah M, Cornetta K, Davies KE, Dickson JG, Duchateau P, Flotte TR, Gaudet D, Gersbach CA, Gilbert R, Glorioso J, Herzog RW, High KA, Huang W, Huard J, Joung JK, Liu D, Liu D, Lochmüller H, Lustig L, Martens J, Massie B, Mavilio F, Mendell JR, Nathwani A, Ponder K, Porteus M, Puymirat J, Samulski J, Takeda S, Thrasher A, Vandendriessche T, Wei Y, Wilson JM, Wilton SD, Wolfe JH, Gao G

Translating the Genomics Revolution: The Need for an International Gene Therapy Consortium for Monogenic Diseases.
Mol Ther. 2013;21(2):266-268 - PMID: 23369965 - PMCID: PMC3594019 - DOI: 10.1038/mt.2013.4
Total: 2498