Publications for All Faculty

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Wyatt KD, Stuart LM, Brito JP, Carranza Leon B, Domecq JP, Prutsky GJ, Egginton JS, Calvin AD, Shah ND, Murad MH, Montori VM

Out of Context: Clinical Practice Guidelines and Patients With Multiple Chronic Conditions: A Systematic Review.
Med Care. 2014;52 Suppl 3:S92-S100 - PMID: 23969592 - DOI: 10.1097/MLR.0b013e3182a51b3d

Conway KL, Kuballa P, Song JH, Patel KK, Castoreno AB, Yilmaz OH, Jijon HB, Zhang M, Aldrich LN, Villablanca EJ, Peloquin JM, Goel G, Lee IA, Mizoguchi E, Shi HN, Bhan AK, Shaw SY, Schreiber SL, Virgin HW, Shamji AF, Stappenbeck TS, Reinecker HC, Xavier RJ

Atg16l1 is Required for Autophagy in Intestinal Epithelial Cells and Protection of Mice from Salmonella Infection.
Gastroenterology. 2013;145(6):1347-57 - PMID: 23973919 - PMCID: PMC3840157 - DOI: 10.1053/j.gastro.2013.08.035

Rae L, Pham TN, Carrougher G, Honari S, Gibran NS, Arnoldo BD, Gamelli RL, Tompkins RG, Herndon DN

Differences in Resuscitation in Morbidly Obese Burn Patients May Contribute to High Mortality.
J Burn Care Res. 2013;34(5):507-14 - PMID: 23966116 - PMCID: PMC3800202 - DOI: 10.1097/BCR.0b013e3182a2a771

Sander JD, Ramirez CL, Linder SJ, Pattanayak V, Shoresh N, Ku M, Foden JA, Reyon D, Bernstein BE, Liu DR, Joung JK

In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites.
Nucleic Acids Res. 2013;41(19):e181 - PMID: 23945932 - PMCID: PMC3799455 - DOI: 10.1093/nar/gkt716

He C, Wei Y, Sun K, Li B, Dong X, Zou Z, Liu Y, Kinch LN, Khan S, Sinha S, Xavier RJ, Grishin NV, Xiao G, Eskelinen EL, Scherer PE, Whistler JL, Levine B

Beclin 2 Functions in Autophagy, Degradation of G Protein-Coupled Receptors, and Metabolism.
Cell. 2013;154(5):1085-99 - PMID: 23954414 - PMCID: PMC4231430 - DOI: 10.1016/j.cell.2013.07.035

Wang SC, Tsai CH, Hou CP, Lee SY, Ko SF, Hsiao CC, Chen YC, Chuang JH, Sheen JM

Dislodgement of port-A catheters in pediatric oncology patients: 11 years of experience.
World J Surg Oncol. 2013;11(1):191 - PMID: 23941644 - PMCID: PMC3765137 - DOI: 10.1186/1477-7819-11-191

Li JF, Norville JE, Aach J, McCormack M, Zhang D, Bush J, Church GM, Sheen J

Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9.
Nat Biotechnol. 2013;31(8):688-91 - PMID: 23929339 - PMCID: PMC4078740 - DOI: 10.1038/nbt.2654

Warren HS, Tompkins RG, Mindrinos MN, Xiao W, Davis RW

Reply to Cauwels et al.: Of men, not mice, and inflammation.
Proc Natl Acad Sci U S A. 2013;110(34):E3151 - PMID: 24137663 - PMCID: PMC3752239 - DOI: 10.1073/pnas.1308943110

Börnigen D, Morgan XC, Franzosa EA, Ren B, Xavier RJ, Garrett WS, Huttenhower C

Functional profiling of the gut microbiome in disease-associated inflammation.
Genome Med. 2013;5(7):65 - PMID: 23906180 - PMCID: PMC3978847 - DOI: 10.1186/gm469

Candy PA, Phillips MR, Redfern AD, Colley SM, Davidson JA, Stuart LM, Wood BA, Zeps N, Leedman PJ

Notch-induced transcription factors are predictive of survival and 5-fluorouracil response in colorectal cancer patients.
Br J Cancer. 2013;109(4):1023-30 - PMID: 23900217 - PMCID: PMC3749585 - DOI: 10.1038/bjc.2013.431

Grant SS, Kawate T, Nag PP, Silvis MR, Gordon K, Stanley SA, Kazyanskaya E, Nietupski R, Golas A, Fitzgerald M, Cho S, Franzblau SG, Hung DT

Identification of novel inhibitors of non-replicating M. tuberculosis using a carbon starvation model.
ACS Chem Biol. 2013;8(10):2224-34 - PMID: 23898841 - PMCID: PMC3864639 - DOI: 10.1021/cb4004817

Maeder ML, Linder SJ, Cascio VM, Fu Y, Ho QH, Joung JK

CRISPR RNA-guided activation of endogenous human genes.
Nat Methods. 2013;10(10):977-9 - PMID: 23892898 - PMCID: PMC3794058 - DOI: 10.1038/nmeth.2598

Jeschke MG, Finnerty CC, Emdad F, Rivero HG, Kraft R, Williams FN, Gamelli RL, Gibran NS, Klein MB, Arnoldo BD, Tompkins RG, Herndon DN

Mild Obesity Is Protective After Severe Burn Injury.
Ann Surg. 2013;258(6):1119-29 - PMID: 23877367 - PMCID: PMC3963145 - DOI: 10.1097/SLA.0b013e3182984d19

Ananthakrishnan AN, Oxford EC, Nguyen DD, Sauk J, Yajnik V, Xavier RJ

Genetic risk factors for Clostridium difficile infection in ulcerative colitis.
Aliment Pharmacol Ther. 2013;38(5):522-30 - PMID: 23848254 - PMCID: PMC3755009 - DOI: 10.1111/apt.12425

Poutahidis T, Kleinewietfeld M, Smillie C, Levkovich T, Perrotta A, Bhela S, Varian BJ, Ibrahim YM, Lakritz JR, Kearney SM, Chatzigiagkos A, Hafler DA, Alm EJ, Erdman SE

Microbial reprogramming inhibits Western diet-associated obesity.
PLoS One. 2013;8(7):e68596 - PMID: 23874682 - PMCID: PMC3707834 - DOI: 10.1371/journal.pone.0068596

Hwang WY, Fu Y, Reyon D, Maeder ML, Kaini P, Sander JD, Joung JK, Peterson RT, Yeh JR

Heritable and Precise Zebrafish Genome Editing Using a CRISPR-Cas System.
PLoS One. 2013;8(7):e68708 - PMID: 23874735 - PMCID: PMC3706373 - DOI: 10.1371/journal.pone.0068708

Hett EC, Slater LH, Mark KG, Kawate T, Monks BG, Stutz A, Latz E, Hung DT

Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis.
Nat Chem Biol. 2013;9(7):466 - PMID: 23774875

Adamala K, Szostak JW

Competition between model protocells driven by an encapsulated catalyst.
Nat Chem. 2013;5(7):634 - PMID: 23787756

Reyon D, Maeder ML, Khayter C, Tsai SQ, Foley JE, Sander JD, Joung JK

Engineering Customized TALE Nucleases (TALENs) and TALE Transcription Factors by Fast Ligation-Based Automatable Solid-Phase High-Throughput (FLASH) Assembly.
Curr Protoc Mol Biol. 2013;Chapter 12:Unit12.16 - PMID: 23821439 - PMCID: PMC3767754 - DOI: 10.1002/0471142727.mb1216s103

Karlsson EK, Harris JB, Tabrizi S, Rahman A, Shlyakhter I, Patterson N, O'Dushlaine C, Schaffner SF, Gupta S, Chowdhury F, Sheikh A, Shin OS, Ellis C, Becker CE, Stuart LM, Calderwood SB, Ryan ET, Qadri F, Sabeti PC, Larocque RC

Natural selection in a bangladeshi population from the cholera-endemic ganges river delta.
Sci Transl Med. 2013;5(192):192ra86 - PMID: 23825302 - PMCID: PMC4367964 - DOI: 10.1126/scitranslmed.3006338

Sheedy FJ, Grebe A, Rayner KJ, Kalantari P, Ramkhelawon B, Carpenter SB, Becker CE, Ediriweera HN, Mullick AE, Golenbock DT, Stuart LM, Latz E, Fitzgerald KA, Moore KJ

CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation.
Nat Immunol. 2013;14(8):812-20 - PMID: 23812099 - PMCID: PMC3720827 - DOI: 10.1038/ni.2639

Stanley SA, Kawate T, Iwase N, Shimizu M, Clatworthy AE, Kazyanskaya E, Sacchettini JC, Ioerger TR, Siddiqi NA, Minami S, Aquadro JA, Schmidt Grant S, Rubin EJ, Hung DT

Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32.
Proc Natl Acad Sci U S A. 2013;110(28):11565-70 - PMID: 23798446 - PMCID: PMC3710825 - DOI: 10.1073/pnas.1302114110

Fu Y, Foden JA, Khayter C, Maeder ML, Reyon D, Joung JK, Sander JD

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells.
Nat Biotechnol. 2013;31(9):822-6 - PMID: 23792628 - PMCID: PMC3773023 - DOI: 10.1038/nbt.2623

Smeekens SP, Huttenhower C, Riza A, van de Veerdonk FL, Zeeuwen PL, Schalkwijk J, van der Meer JW, Xavier RJ, Netea MG, Gevers D

Skin Microbiome Imbalance in Patients with STAT1/STAT3 Defects Impairs Innate Host Defense Responses.
J Innate Immun. 2013;6(3):253-62 - PMID: 23796786 - PMCID: PMC4045018 - DOI: 10.1159/000351912

Xiong Y, Sheen J

Moving beyond translation: glucose-TOR signaling in the transcriptional control of cell cycle.
Cell Cycle. 2013;12(13):1989-90 - PMID: 23759578 - PMCID: PMC3737295 - DOI: 10.4161/cc.25308
Total: 2498