Publications for All Faculty

Sort by:
Kleinnijenhuis J, Quintin J, Preijers F, Benn CS, Joosten LA, Jacobs C, van Loenhout J, Xavier RJ, Aaby P, van der Meer JW, van Crevel R, Netea MG

Long-Lasting Effects of BCG Vaccination on Both Heterologous Th1/Th17 Responses and Innate Trained Immunity.

J Innate Immun. 2013;6(2):152-8 - PMID: 24192057 - PMCID: PMC3944069 - DOI: 10.1159/000355628
Shaw SY, Tran K, Castoreno AB, Peloquin JM, Lassen KG, Khor B, Aldrich LN, Tan PH, Graham DB, Kuballa P, Goel G, Daly MJ, Shamji AF, Schreiber SL, Xavier RJ

Selective Modulation of Autophagy, Innate Immunity, and Adaptive Immunity by Small Molecules.

ACS Chem Biol. 2013;8(12):2724-33 - PMID: 24168452 - PMCID: PMC3951132 - DOI: 10.1021/cb400352d
Soukas AA, Carr CE, Ruvkun G

Genetic Regulation of Caenorhabditis elegans Lysosome Related Organelle Function.

PLoS Genet. 2013;9(10):e1003908 - PMID: 24204312 - PMCID: PMC3812091 - DOI: 10.1371/journal.pgen.1003908
Josephson K, Ricardo A, Szostak JW

mRNA display: from basic principles to macrocycle drug discovery.

Drug Discov Today. 2014;19(4):388-99 - PMID: 24157402 - DOI: 10.1016/j.drudis.2013.10.011
Maeder ML, Angstman JF, Richardson ME, Linder SJ, Cascio VM, Tsai SQ, Ho QH, Sander JD, Reyon D, Bernstein BE, Costello JF, Wilkinson MF, Joung JK

Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins.

Nat Biotechnol. 2013;31(12):1137-42 - PMID: 24108092 - PMCID: PMC3858462 - DOI: 10.1038/nbt.2726
Zhang S, Blain JC, Zielinska D, Gryaznov SM, Szostak JW

Fast and accurate nonenzymatic copying of an RNA-like synthetic genetic polymer.

Proc Natl Acad Sci U S A. 2013;110(44):17732-7 - PMID: 24101473 - PMCID: PMC3816440 - DOI: 10.1073/pnas.1312329110
Sandoval GJ, Graham DB, Gmyrek GB, Akilesh HM, Fujikawa K, Sammut B, Bhattacharya D, Srivatsan S, Kim A, Shaw AS, Yang-Iott K, Bassing CH, Duncavage E, Xavier RJ, Swat W

Novel Mechanism of Tumor Suppression by Polarity Gene Discs Large 1 (DLG1) Revealed in a Murine Model of Pediatric B-ALL.

Cancer Immunol Res. 2013;1(6):426-37 - PMID: 24778134 - PMCID: PMC4006353 - DOI: 10.1158/2326-6066.CIR-13-0065
Knights D, Lassen KG, Xavier RJ

Advances in inflammatory bowel disease pathogenesis: linking host genetics and the microbiome.

Gut. 2013;62(10):1505-10 - PMID: 24037875 - PMCID: PMC3822528 - DOI: 10.1136/gutjnl-2012-303954
Tabach Y, Golan T, Hernández-Hernández A, Messer AR, Fukuda T, Kouznetsova A, Liu JG, Lilienthal I, Levy C, Ruvkun G

Human disease locus discovery and mapping to molecular pathways through phylogenetic profiling.

Mol Syst Biol. 2013;9:692 - PMID: 24084807 - PMCID: PMC3817400 - DOI: 10.1038/msb.2013.50
Tzika AA, Constantinou C, Bandyopadhaya A, Psychogios N, Lee S, Mindrinos M, Martyn JA, Tompkins RG, Rahme LG

A Small Volatile Bacterial Molecule Triggers Mitochondrial Dysfunction in Murine Skeletal Muscle.

PLoS One. 2013;8(9):e74528 - PMID: 24098655 - PMCID: PMC3787027 - DOI: 10.1371/journal.pone.0074528
Vandussen KL, Liu TC, Li D, Towfic F, Modiano N, Winter R, Haritunians T, Taylor KD, Dhall D, Targan SR, Xavier RJ, McGovern DP, Stappenbeck TS

Genetic Variants Synthesize to Produce Paneth Cell Phenotypes that Define Subtypes of Crohn's Disease.

Gastroenterology. 2014;146(1):200-9 - PMID: 24076061 - PMCID: PMC3899786 - DOI: 10.1053/j.gastro.2013.09.048
Kawate T, Iwase N, Shimizu M, Stanley SA, Wellington S, Kazyanskaya E, Hung DT

Synthesis and structure-activity relationships of phenyl-substituted coumarins with anti-tubercular activity that target FadD32.

Bioorg Med Chem Lett. 2013;23(22):6052-9 - PMID: 24103299 - DOI: 10.1016/j.bmcl.2013.09.035
Shi Z, Hayes G, Ruvkun G

Dual Regulation of the lin-14 Target mRNA by the lin-4 miRNA.

PLoS One. 2013;8(9):e75475 - PMID: 24058689 - PMCID: PMC3772890 - DOI: 10.1371/journal.pone.0075475
Beaudoin M, Goyette P, Boucher G, Lo KS, Rivas MA, Stevens C, Alikashani A, Ladouceur M, Ellinghaus D, Törkvist L, Goel G, Lagacé C, Annese V, Bitton A, Begun J, Brant SR, Bresso F, Cho JH, Duerr RH, Halfvarson J, McGovern DP, Radford-Smith G, Schreiber S, Schumm PL, Sharma Y, Silverberg MS, Weersma RK, , , , D'Amato M, Vermeire S, Franke A, Lettre G, Xavier RJ, Daly MJ, Rioux JD

Deep Resequencing of GWAS Loci Identifies Rare Variants in CARD9, IL23R and RNF186 That Are Associated with Ulcerative Colitis.

PLoS Genet. 2013;9(9):e1003723 - PMID: 24068945 - PMCID: PMC3772057 - DOI: 10.1371/journal.pgen.1003723
Giles KM, Kalinowski FC, Candy PA, Epis MR, Zhang PM, Redfern AD, Stuart LM, Goodall GJ, Leedman PJ

Axl mediates acquired resistance of head and neck cancer cells to the epidermal growth factor receptor inhibitor erlotinib.

Mol Cancer Ther. 2013;12(11):2541-58 - PMID: 24026012 - DOI: 10.1158/1535-7163.MCT-13-0170
Mendenhall EM, Williamson KE, Reyon D, Zou JY, Ram O, Joung JK, Bernstein BE

Locus-specific editing of histone modifications at endogenous enhancers.

Nat Biotechnol. 2013;31(12):1133-6 - PMID: 24013198 - PMCID: PMC3858395 - DOI: 10.1038/nbt.2701
Cheng C, Gao X, Feng B, Sheen J, Shan L, He P

Plant immune response to pathogens differs with changing temperatures.

Nat Commun. 2013;4:2530 - PMID: 24067909 - PMCID: PMC3901997 - DOI: 10.1038/ncomms3530
Tompkins RG, Warren HS, Mindrinos MN, Xiao W, Davis RW

Reply to Osterburg et al.: To study human inflammatory diseases in humans.

Proc Natl Acad Sci U S A. 2013;110(36):E3371 - PMID: 24137798 - PMCID: PMC3767510 - DOI: 10.1073/pnas.1307452110
Qi Y, Li X, Zhang Y, Starker CG, Baltes NJ, Zhang F, Sander JD, Reyon D, Joung JK, Voytas DF

Targeted Deletion and Inversion of Tandemly Arrayed Genes in Arabidopsis thaliana Using Zinc Finger Nucleases.

G3 (Bethesda). 2013;3(10):1707-1715 - PMID: 23979943 - PMCID: PMC3789795 - DOI: 10.1534/g3.113.006270
Wyatt KD, Stuart LM, Brito JP, Carranza Leon B, Domecq JP, Prutsky GJ, Egginton JS, Calvin AD, Shah ND, Murad MH, Montori VM

Out of Context: Clinical Practice Guidelines and Patients With Multiple Chronic Conditions: A Systematic Review.

Med Care. 2014;52 Suppl 3:S92-S100 - PMID: 23969592 - DOI: 10.1097/MLR.0b013e3182a51b3d
Conway KL, Kuballa P, Song JH, Patel KK, Castoreno AB, Yilmaz OH, Jijon HB, Zhang M, Aldrich LN, Villablanca EJ, Peloquin JM, Goel G, Lee IA, Mizoguchi E, Shi HN, Bhan AK, Shaw SY, Schreiber SL, Virgin HW, Shamji AF, Stappenbeck TS, Reinecker HC, Xavier RJ

Atg16l1 is Required for Autophagy in Intestinal Epithelial Cells and Protection of Mice from Salmonella Infection.

Gastroenterology. 2013;145(6):1347-57 - PMID: 23973919 - PMCID: PMC3840157 - DOI: 10.1053/j.gastro.2013.08.035
Rae L, Pham TN, Carrougher G, Honari S, Gibran NS, Arnoldo BD, Gamelli RL, Tompkins RG, Herndon DN

Differences in Resuscitation in Morbidly Obese Burn Patients May Contribute to High Mortality.

J Burn Care Res. 2013;34(5):507-14 - PMID: 23966116 - PMCID: PMC3800202 - DOI: 10.1097/BCR.0b013e3182a2a771
Sander JD, Ramirez CL, Linder SJ, Pattanayak V, Shoresh N, Ku M, Foden JA, Reyon D, Bernstein BE, Liu DR, Joung JK

In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites.

Nucleic Acids Res. 2013;41(19):e181 - PMID: 23945932 - PMCID: PMC3799455 - DOI: 10.1093/nar/gkt716
He C, Wei Y, Sun K, Li B, Dong X, Zou Z, Liu Y, Kinch LN, Khan S, Sinha S, Xavier RJ, Grishin NV, Xiao G, Eskelinen EL, Scherer PE, Whistler JL, Levine B

Beclin 2 Functions in Autophagy, Degradation of G Protein-Coupled Receptors, and Metabolism.

Cell. 2013;154(5):1085-99 - PMID: 23954414 - PMCID: PMC4231430 - DOI: 10.1016/j.cell.2013.07.035
Wang SC, Tsai CH, Hou CP, Lee SY, Ko SF, Hsiao CC, Chen YC, Chuang JH, Sheen JM

Dislodgement of port-A catheters in pediatric oncology patients: 11 years of experience.

World J Surg Oncol. 2013;11(1):191 - PMID: 23941644 - PMCID: PMC3765137 - DOI: 10.1186/1477-7819-11-191
Total: 2467