Publications for All Faculty

Sort by:
Reset
Gupta A, Christensen RG, Bell HA, Goodwin M, Patel RY, Pandey M, Enuameh MS, Rayla AL, Zhu C, Thibodeau-Beganny S, Brodsky MH, Joung JK, Wolfe SA, Stormo GD

An improved predictive recognition model for Cys(2)-His(2) zinc finger proteins.

Nucleic Acids Res. 2014;42(8):4800-12 - PMID: 24523353 - PMCID: PMC4005693 - DOI: 10.1093/nar/gku132
Sheng J, Li L, Engelhart AE, Gan J, Wang J, Szostak JW

Structural insights into the effects of 2'-5' linkages on the RNA duplex.

Proc Natl Acad Sci U S A. 2014;111(8):3050-5 - PMID: 24516151 - PMCID: PMC3939906 - DOI: 10.1073/pnas.1317799111
Li L, Szostak JW

The Free Energy Landscape of Pseudorotation in 3'-5' and 2'-5' Linked Nucleic Acids.

J Am Chem Soc. 2014;136(7):2858-65 - PMID: 24499340 - PMCID: PMC3982932 - DOI: 10.1021/ja412079b
Fu Y, Sander JD, Reyon D, Cascio VM, Joung JK

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs.

Nat Biotechnol. 2014;32(3):279-84 - PMID: 24463574 - PMCID: PMC3988262 - DOI: 10.1038/nbt.2808
Fowler SA, Ananthakrishnan AN, Gardet A, Stevens CR, Korzenik JR, Sands BE, Daly MJ, Xavier RJ, Yajnik V

SMAD3 gene variant is a risk factor for recurrent surgery in patients with Crohn's disease.

J Crohns Colitis. 2014;8(8):845-51 - PMID: 24461721 - PMCID: PMC4237062 - DOI: 10.1016/j.crohns.2014.01.003
Ananthakrishnan AN, Huang H, Nguyen DD, Sauk J, Yajnik V, Xavier RJ

Differential Effect of Genetic Burden on Disease Phenotypes in Crohn's Disease and Ulcerative Colitis: Analysis of a North American Cohort.

Am J Gastroenterol. 2014;109(3):395-400 - PMID: 24419484 - PMCID: PMC4225079 - DOI: 10.1038/ajg.2013.464
Lee E, Koo Y, Ng A, Wei Y, Luby-Phelps K, Juraszek A, Xavier RJ, Cleaver O, Levine B, Amatruda JF

Autophagy is essential for cardiac morphogenesis during vertebrate development.

Autophagy. 2014;10(4):572-87 - PMID: 24441423 - PMCID: PMC4091146 - DOI: 10.4161/auto.27649
Zhao G, Yu YM, Shoup TM, Elmaleh DR, Bonab AA, Tompkins RG, Fischman AJ

Membrane potential-dependent uptake of (18)F-triphenylphosphonium-a new voltage sensor as an imaging agent for detecting burn-induced apoptosis.

J Surg Res. 2014;188(2):473-9 - PMID: 24582214 - PMCID: PMC3988254 - DOI: 10.1016/j.jss.2014.01.011
Blain JC, Ricardo A, Szostak JW

Synthesis and Non-Enzymatic Template-Directed Polymerization of 2'-Amino-2'-Deoxythreose Nucleotides.

J Am Chem Soc. 2014;136(5):2033-9 - PMID: 24409991 - PMCID: PMC4105081 - DOI: 10.1021/ja411950n
Pauli A, Norris ML, Valen E, Chew GL, Gagnon JA, Zimmerman S, Mitchell A, Ma J, Dubrulle J, Reyon D, Tsai SQ, Joung JK, Saghatelian A, Schier AF

Toddler: an embryonic signal that promotes cell movement via Apelin receptors.

Science. 2014;343(6172):1248636 - PMID: 24407481 - PMCID: PMC4107353 - DOI: 10.1126/science.1248636
Xiong Y, Sheen J

TOR Signaling Networks in Plant Growth and Metabolism.

Plant Physiol. 2014;164(2):499-512 - PMID: 24385567 - PMCID: PMC3912084 - DOI: 10.1104/pp.113.229948
Slater LH, Clatworthy AE, Hung DT

Bacterial toxins and small molecules elucidate endosomal trafficking.

Trends Microbiol. 2014;22(2):53-5 - PMID: 24370463 - DOI: 10.1016/j.tim.2013.12.002
Low BE, Krebs MP, Joung JK, Tsai SQ, Nishina PM, Wiles MV

Correction of Crb1rd8 allele and retinal phenotype in C57BL/6N mice via TALEN-mediated homology-directed repair.

Invest Ophthalmol Vis Sci. 2014;55(1):387-395 - PMID: 24346171 - PMCID: PMC3921157 - DOI: 10.1167/iovs.13-13278
Hamel LP, Sheen J, Séguin A

Ancient signals: comparative genomics of green plant CDPKs.

Trends Plant Sci. 2014;19(2):79-89 - PMID: 24342084 - PMCID: PMC3932502 - DOI: 10.1016/j.tplants.2013.10.009
De Nardo D, Labzin LI, Kono H, Seki R, Schmidt SV, Beyer M, Xu D, Zimmer S, Lahrmann C, Schildberg FA, Vogelhuber J, Kraut M, Ulas T, Kerksiek A, Krebs W, Bode N, Grebe A, Fitzgerald ML, Hernandez NJ, Williams BR, Knolle P, Kneilling M, Röcken M, Lütjohann D, Wright SD, Schultze JL, Latz E

High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3.

Nat Immunol. 2014;15(2):152-60 - PMID: 24317040 - PMCID: PMC4009731 - DOI: 10.1038/ni.2784
Fischer SE, Pan Q, Breen PC, Qi Y, Shi Z, Zhang C, Ruvkun G

Multiple small RNA pathways regulate the silencing of repeated and foreign genes in C. elegans.

Genes Dev. 2013;27(24):2678-95 - PMID: 24352423 - PMCID: PMC3877757 - DOI: 10.1101/gad.233254.113
Kieffer-Kwon KR, Tang Z, Mathe E, Qian J, Sung MH, Li G, Resch W, Baek S, Pruett N, Grøntved L, Vian L, Nelson S, Zare H, Hakim O, Reyon D, Yamane A, Nakahashi H, Kovalchuk AL, Zou J, Joung JK, Sartorelli V, Wei CL, Ruan X, Hager GL, Ruan Y, Casellas R

Interactome maps of mouse gene regulatory domains reveal basic principles of transcriptional regulation.

Cell. 2013;155(7):1507-20 - PMID: 24360274 - PMCID: PMC3905448 - DOI: 10.1016/j.cell.2013.11.039
Haller JF, Cavallaro P, Hernandez NJ, Dolat L, Soscia SJ, Welti R, Grabowski GA, Fitzgerald ML, Freeman MW

Endogenous ?-glucocerebrosidase activity in Abca12-/-epidermis elevates ceramide levels after topical lipid application but does not restore barrier function.

J Lipid Res. 2014;55(3):493-503 - PMID: 24293640 - PMCID: PMC3934733 - DOI: 10.1194/jlr.M044941
Groen SC, Whiteman NK, Bahrami AK, Wilczek AM, Cui J, Russell JA, Cibrian-Jaramillo A, Butler IA, Rana JD, Huang GH, Bush J, Ausubel FM, Pierce NE

Pathogen-Triggered Ethylene Signaling Mediates Systemic-Induced Susceptibility to Herbivory in Arabidopsis.

Plant Cell. 2013;25(11):4755-66 - PMID: 24285796 - PMCID: PMC3875748 - DOI: 10.1105/tpc.113.113415
Liu Y, Shoji-Kawata S, Sumpter RM, Wei Y, Ginet V, Zhang L, Posner B, Tran KA, Green DR, Xavier RJ, Shaw SY, Clarke PG, Puyal J, Levine B

Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia.

Proc Natl Acad Sci U S A. 2013;110(51):20364-71 - PMID: 24277826 - PMCID: PMC3870705 - DOI: 10.1073/pnas.1319661110
Zhou GL, Beloiartsev A, Yu B, Baron DM, Zhou W, Niedra R, Lu N, Tainsh LT, Zapol WM, Seed B, Bloch KD

Deletion of the Murine Cytochrome P450 Cyp2j Locus by Fused BAC-Mediated Recombination Identifies a Role for Cyp2j in the Pulmonary Vascular Response to Hypoxia.

PLoS Genet. 2013;9(11):e1003950 - PMID: 24278032 - PMCID: PMC3836722 - DOI: 10.1371/journal.pgen.1003950
Schwartz S, Agarwala SD, Mumbach MR, Jovanovic M, Mertins P, Shishkin A, Tabach Y, Mikkelsen TS, Satija R, Ruvkun G, Carr SA, Lander ES, Fink GR, Regev A

High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis.

Cell. 2013;155(6):1409-21 - PMID: 24269006 - PMCID: PMC3956118 - DOI: 10.1016/j.cell.2013.10.047
Zhou J, Wu S, Chen X, Liu C, Sheen J, Shan L, He P

Pseudomonas syringae Effector HopF2 Suppresses Arabidopsis Immunity by Targeting BAK1.

Plant J. 2014;77(2):235-45 - PMID: 24237140 - PMCID: PMC4224013 - DOI: 10.1111/tpj.12381
Smeekens SP, Malireddi RK, Plantinga TS, Buffen K, Oosting M, Joosten LA, Kullberg BJ, Perfect JR, Scott WK, van de Veerdonk FL, Xavier RJ, van de Vosse E, Kanneganti TD, Johnson MD, Netea MG

Autophagy is redundant for the host defense against systemic Candida albicans infections.

Eur J Clin Microbiol Infect Dis. 2014;33(5):711-22 - PMID: 24202731 - DOI: 10.1007/s10096-013-2002-x
Zhu TF, Budin I, Szostak JW

Preparation of Fatty Acid micelles.

Methods Enzymol. 2013;533:283-8 - PMID: 24182934 - PMCID: PMC4310231 - DOI: 10.1016/B978-0-12-420067-8.00022-2
Total: 2473